产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
缺氧诱导因子1A
目录 :
20960-1-AP
规格 :
150UL
价格 :
299美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀
更多信息或购买 :
文章摘录数: 144
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 4a
Xiang J, Hu Q, Qin Y, Ji S, Xu W, Liu W, et al. TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer. Cell Death Dis. 2018;9:321 pubmed 出版商
  • 免疫印迹; 大鼠; 1:800; 图 4
Li X, Chen Y, Wang L, Shang G, Zhang C, Zhao Z, et al. Quercetin alleviates pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. Braz J Med Biol Res. 2016;49: pubmed 出版商
Wang Y, Yang B, Lai Q, Shi J, Peng J, Zhang Y, et al. Reprogramming of m6A epitranscriptome is crucial for shaping of transcriptome and proteome in response to hypoxia. RNA Biol. 2020;:1-13 pubmed 出版商
Wang X, Lin Y, Zheng Y. Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration. Mol Med Rep. 2020;22:2318-2328 pubmed 出版商
Zhong L, Wang R, Wang Y, Peng S, Ma Y, Ding S, et al. Dual inhibition of VEGF and PARP suppresses KRAS-mutant colorectal cancer. Neoplasia. 2020;22:365-375 pubmed 出版商
Yan X, Yang C, Hu W, Chen T, Wang Q, Pan F, et al. Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway. Oncol Rep. 2020;44:103-114 pubmed 出版商
Ndibalema A, Kabuye D, Wen S, Li L, Li X, Fan Q. Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha. Diabetes Metab Syndr Obes. 2020;13:1953-1967 pubmed 出版商
Wang S, Zhong X, Wang C, Luo H, Lin L, Sun H, et al. USP22 positively modulates ERα action via its deubiquitinase activity in breast cancer. Cell Death Differ. 2020;: pubmed 出版商
Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, et al. Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells. Life Sci. 2020;255:117846 pubmed 出版商
Han X, Ma W, Zhu Y, Sun X, Liu N. Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway. Mol Cell Endocrinol. 2020;514:110878 pubmed 出版商
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D. Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway. Life Sci. 2020;255:117719 pubmed 出版商
Hua Q, Mi B, Xu F, Wen J, Zhao L, Liu J, et al. Hypoxia-induced lncRNA-AC020978 promotes proliferation and glycolytic metabolism of non-small cell lung cancer by regulating PKM2/HIF-1α axis. Theranostics. 2020;10:4762-4778 pubmed 出版商
Lin H, Zhou W, Huang Y, Ren M, Xu F, Wang H. Systemic hypoxia potentiates anti-tumor effects of metformin in hepatocellular carcinoma in mice. Acta Biochim Biophys Sin (Shanghai). 2020;52:421-429 pubmed 出版商
Luo J, Luo X, Liu X, Fang Z, Xu J, Li L. DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway. Onco Targets Ther. 2020;13:1321-1330 pubmed 出版商
Tang B, Tang M, Xu Q, Guo J, Xuan L, Zhou J, et al. MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α. J Biosci. 2020;45: pubmed
Yin X, Xia J, Sun Y, Zhang Z. CHCHD2 is a potential prognostic factor for NSCLC and is associated with HIF-1a expression. BMC Pulm Med. 2020;20:40 pubmed 出版商
Cai Q, Wang X, Wang S, Jin L, Ding J, Zhou D, et al. Gallbladder Cancer Progression Is Reversed by Nanomaterial-Induced Photothermal Therapy in Combination with Chemotherapy and Autophagy Inhibition. Int J Nanomedicine. 2020;15:253-262 pubmed 出版商
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Qin S, Yi M, Jiao D, Li A, Wu K. Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma. J Cancer. 2020;11:153-167 pubmed 出版商
Gao P, Wang L, Liu J, Dong F, Song W, Liao L, et al. Dihydroartemisinin inhibits endothelial cell tube formation by suppression of the STAT3 signaling pathway. Life Sci. 2020;242:117221 pubmed 出版商
Xiao T, Sun J, Xing Z, Xie F, Yang L, Ding W. MTFP1 overexpression promotes the growth of oral squamous cell carcinoma by inducing ROS production. Cell Biol Int. 2020;44:821-829 pubmed 出版商
Xu W, Zheng H, Yang R, Jiang L, Jiang S. HIF-1α Regulates Glucocorticoid-Induced Osteoporosis Through PDK1/AKT/mTOR Signaling Pathway. Front Endocrinol (Lausanne). 2019;10:922 pubmed 出版商
Zhang X, Ma N, Yao W, Li S, Ren Z. RAD51 is a potential marker for prognosis and regulates cell proliferation in pancreatic cancer. Cancer Cell Int. 2019;19:356 pubmed 出版商
Pan C, Liu Q, Wu X. HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells. Cancer Manag Res. 2019;11:10145-10156 pubmed 出版商
Chai X, Le Y, Wang J, Mei C, Feng J, Zhao H, et al. Carpesium abrotanoides (L.) Root as a Potential Source of Natural Anticancer Compounds: Targeting Glucose Metabolism and PKM2/HIF-1α Axis of Breast Cancer Cells. J Food Sci. 2019;84:3825-3832 pubmed 出版商
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X. Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts. Int J Mol Med. 2019;: pubmed 出版商
Xu W, Zheng H, Yang R, Liu T, Yu W, Zheng X, et al. Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy. Exp Mol Med. 2019;51:140 pubmed 出版商
Sun C, Li X, Guo E, Li N, Zhou B, Lu H, et al. MCP-1/CCR-2 axis in adipocytes and cancer cell respectively facilitates ovarian cancer peritoneal metastasis. Oncogene. 2019;: pubmed 出版商
Ohta S, Morine Y, Imura S, Ikemoto T, Arakawa Y, Iwahashi S, et al. Carbohydrate Antigen 19-9 Is a Prognostic Factor Which Correlates With HDAC1 and HIF-1α for Intrahepatic Cholangiocarcinoma. Anticancer Res. 2019;39:6025-6033 pubmed 出版商
Zhu Y, Yu F, Tan Y, Hong Y, Meng T, Liu Y, et al. Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells. Theranostics. 2019;9:6764-6779 pubmed 出版商
Chu X, Xiang M, Feng L, Liu H, Zhou C. Prolyl hydroxylase 3 involvement in lung cancer progression under hypoxic conditions: association with hypoxia-inducible factor-1α and pyruvate kinase M2. J Thorac Dis. 2019;11:3941-3950 pubmed 出版商
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Lian G, Li X, Zhang L, Zhang Y, Sun L, Zhang X, et al. Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway✰. EBioMedicine. 2019;49:291-304 pubmed 出版商
Bera R, Chiu M, Huang Y, Lin T, Kuo M, Shih L. RUNX1 mutations promote leukemogenesis of myeloid malignancies in ASXL1-mutated leukemia. J Hematol Oncol. 2019;12:104 pubmed 出版商
Qian X, Li X, Shi Z, Bai X, Xia Y, Zheng Y, et al. KDM3A Senses Oxygen Availability to Regulate PGC-1α-Mediated Mitochondrial Biogenesis. Mol Cell. 2019;: pubmed 出版商
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Li J, Yuan Y, Zhang L, Zhang H, Zhang S, Zhang Y, et al. Exogenous hydrogen sulfide protects against high glucose-induced apoptosis and oxidative stress by inhibiting the STAT3/HIF-1α pathway in H9c2 cardiomyocytes. Exp Ther Med. 2019;18:3948-3958 pubmed 出版商
Zhang Y, Liu D, Hu H, Zhang P, Xie R, Cui W. HIF-1α/BNIP3 signaling pathway-induced-autophagy plays protective role during myocardial ischemia-reperfusion injury. Biomed Pharmacother. 2019;120:109464 pubmed 出版商
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Huang R, Jin X, Gao Y, Yuan H, Wang F, Cao X. DZNep inhibits Hif-1α and Wnt signalling molecules to attenuate the proliferation and invasion of BGC-823 gastric cancer cells. Oncol Lett. 2019;18:4308-4316 pubmed 出版商
Hu Y, Lou X, Wang R, Sun C, Liu X, Liu S, et al. Aspirin, a Potential GLUT1 Inhibitor in a Vascular Endothelial Cell Line. Open Med (Wars). 2019;14:552-560 pubmed 出版商
Dai W, Wang Y, Yang T, Wang J, Wu W, Gu J. Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals. Cell Commun Signal. 2019;17:113 pubmed 出版商
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Liu Y, Li Y, Huang Z, Wang Z, Nan L, Wang F, et al. The effect of intervertebral disc degenerative change on biological characteristics of nucleus pulposus mesenchymal stem cell: an in vitro study in rats. Connect Tissue Res. 2019;60:376-388 pubmed 出版商
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, et al. PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:204 pubmed 出版商
Kang L, Shen L, Lu L, Wang D, Zhao Y, Chen C, et al. Asparaginyl endopeptidase induces endothelial permeability and tumor metastasis via downregulating zonula occludens protein ZO-1. Biochim Biophys Acta Mol Basis Dis. 2019;: pubmed 出版商
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Liu D, Zhang Y, Hu H, Zhang P, Cui W. Downregulation of microRNA‑199a‑5p attenuates hypoxia/reoxygenation‑induced cytotoxicity in cardiomyocytes by targeting the HIF‑1α‑GSK3β‑mPTP axis. Mol Med Rep. 2019;19:5335-5344 pubmed 出版商
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Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, et al. Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme. Theranostics. 2019;9:1453-1473 pubmed 出版商
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Li S, Zhao Y, Wang Z, Wang J, Liu C, Sun D. Transplantation of Amniotic Fluid-Derived Stem Cells Preconditioned with Glial Cell Line-Derived Neurotrophic Factor Gene Alleviates Renal Fibrosis. Cell Transplant. 2019;28:65-78 pubmed 出版商
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Geng W, Qin F, Ren J, Xiao S, Wang A. Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice. Exp Cell Res. 2018;369:243-250 pubmed 出版商
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Liu S, Yin Y, Yu R, Li Y, Zhang W. R-spondin3-LGR4 signaling protects hepatocytes against DMOG-induced hypoxia/reoxygenation injury through activating β-catenin. Biochem Biophys Res Commun. 2018;499:59-65 pubmed 出版商
Pang H, Yue S, Tang Y, Chen Y, Tan Y, Cao Y, et al. Integrated Metabolomics and Network Pharmacology Approach to Explain Possible Action Mechanisms of Xin-Sheng-Hua Granule for Treating Anemia. Front Pharmacol. 2018;9:165 pubmed 出版商
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Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P. Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis. Int J Mol Sci. 2018;19: pubmed 出版商
Guo X, Qu J, Zhu C, Li W, Luo L, Yang J, et al. Synchronous delivery of oxygen and photosensitizer for alleviation of hypoxia tumor microenvironment and dramatically enhanced photodynamic therapy. Drug Deliv. 2018;25:585-599 pubmed 出版商
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, et al. Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. Cancer Cell. 2018;33:368-385.e7 pubmed 出版商
Li Y, Wang M, Zhi P, You J, Gao J. Metformin synergistically suppress tumor growth with doxorubicin and reverse drug resistance by inhibiting the expression and function of P-glycoprotein in MCF7/ADR cells and xenograft models. Oncotarget. 2018;9:2158-2174 pubmed 出版商
Chai W, Chen L, Lian X, Zhang Z. Anti-glioma Efficacy and Mechanism of Action of Tripolinolate A from Tripolium pannonicum. Planta Med. 2018;84:786-794 pubmed 出版商
Qiu F, Tong H, Wang Y, Tao J, Wang H, Chen L. Recombinant human maspin inhibits high glucose-induced oxidative stress and angiogenesis of human retinal microvascular endothelial cells via PI3K/AKT pathway. Mol Cell Biochem. 2018;446:127-136 pubmed 出版商
Zhang F, Lu S, He J, Jin H, Wang F, Wu L, et al. Ligand Activation of PPARγ by Ligustrazine Suppresses Pericyte Functions of Hepatic Stellate Cells via SMRT-Mediated Transrepression of HIF-1α. Theranostics. 2018;8:610-626 pubmed 出版商
Zhang X, Liu Z, Xiao Q, Zeng C, Lai C, Fan X, et al. Donor Treatment With a Hypoxia-Inducible Factor-1 Agonist Prevents Donation After Cardiac Death Liver Graft Injury in a Rat Isolated Perfusion Model. Artif Organs. 2018;42:280-289 pubmed 出版商
Zhang C, Bian M, Chen X, Jin H, Zhao S, Yang X, et al. Oroxylin A prevents angiogenesis of LSECs in liver fibrosis via inhibition of YAP/HIF-1α signaling. J Cell Biochem. 2018;119:2258-2268 pubmed 出版商
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Guo X, Xu S, Gao X, Wang J, Xue H, Chen Z, et al. Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells. Oncotarget. 2017;8:80358-80372 pubmed 出版商
Qu J, Guo X, Li W, Hou W, Zhang H, Luo L, et al. Preparation of artificial red cell and its application on alleviation of tumor hypoxia. Colloids Surf B Biointerfaces. 2017;160:446-454 pubmed 出版商
Wang R, Ma J, Wang M, Cui J, Wu W, Liu R, et al. A Human Long Non-Coding RNA ALT1 Controls the Cell Cycle of Vascular Endothelial Cells Via ACE2 and Cyclin D1 Pathway. Cell Physiol Biochem. 2017;43:1152-1167 pubmed 出版商
Ni W, Yang Z, Qi W, Cui C, Cui Y, Xuan Y. Gli1 is a potential cancer stem cell marker and predicts poor prognosis in ductal breast carcinoma. Hum Pathol. 2017;69:38-45 pubmed 出版商
Shang Y, Chen H, Ye J, Wei X, Liu S, Wang R. HIF-1?/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells. Exp Cell Res. 2017;360:243-256 pubmed 出版商
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Wang X, Liow S, Wu Q, Li C, Owh C, Li Z, et al. Codelivery for Paclitaxel and Bcl-2 Conversion Gene by PHB-PDMAEMA Amphiphilic Cationic Copolymer for Effective Drug Resistant Cancer Therapy. Macromol Biosci. 2017;17: pubmed 出版商
Geng J, Wang L, Qu M, Song Y, Lin X, Chen Y, et al. Endothelial progenitor cells transplantation attenuated blood-brain barrier damage after ischemia in diabetic mice via HIF-1?. Stem Cell Res Ther. 2017;8:163 pubmed 出版商
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Liu Y, Tang Q, Shao S, Chen Y, Chen W, Xu X. Lyophilized Powder of Catalpol and Puerarin Protected Cerebral Vessels from Ischemia by Its Anti-apoptosis on Endothelial Cells. Int J Biol Sci. 2017;13:327-338 pubmed 出版商
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图像
图像 1 :
武汉三鹰 20960-1-AP 图像 1
The HIF1a antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human HIF1a. This antibody recognizes human antigen. The HIF1a antibody has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA analysis.
产品信息
目录号 :
20960-1-AP
AntigenName :
缺氧诱导因子1A
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
免疫原 :
融合蛋白
物种 :
鸡, 人类, 小鼠, 大鼠
宿主 :
IsConjugated :
未共轭
AntigenSpecies :
人类
应用 :
免疫印迹, 免疫沉淀, 免疫组化, IF, FC, CoIP, chIP, 酶联免疫吸附测定
Clonlity :
多克隆
抗体亚型 :
IgG
同义词 :
ARNT interacting protein, bHLHe78, HIF 1 alpha, HIF 1alpha, HIF1, HIF1 ALPHA, HIF1A, HIF-1α, Member of PAS protein 1, MOP1, PASD8
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBank登录号 :
BC012527
类别 :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Metabolism;Neurology;Signal transduction;
PurifyMethod :
抗原亲和纯化
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0;IF 1:100;免疫组化1:50;免疫沉淀1:300;免疫印迹1:300;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

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