产品简要
公司名称 :
武汉三鹰
产品类型 :
抗体
产品名称 :
KEAP1
目录 :
60027-1-Ig
规格 :
150UL
价格 :
299美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4G10H9
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:100; 图 7a
Duleh S, Wang X, Komirenko A, Margeta M. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies. Acta Neuropathol Commun. 2016;4:115 pubmed
  • 免疫印迹; 小鼠; 图 1d
Soares M, Cohen O, Low Y, Sartor R, Ellison T, Anil U, et al. Restoration of Nrf2 Signaling Normalizes the Regenerative Niche. Diabetes. 2016;65:633-46 pubmed 出版商
  • 免疫印迹; 人类; 图 3a,3c
Bakkar N, Kousari A, Kovalik T, Li Y, Bowser R. RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1. Mol Cell Biol. 2015;35:2385-99 pubmed 出版商
  • 免疫印迹; 大鼠; 图 1b
Jimenez Blasco D, Santofimia Castaño P, Gonzalez A, Almeida A, Bolaños J. Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway. Cell Death Differ. 2015;22:1877-89 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300; 图 3c
Cescon D, She D, Sakashita S, Zhu C, Pintilie M, Shepherd F, et al. NRF2 Pathway Activation and Adjuvant Chemotherapy Benefit in Lung Squamous Cell Carcinoma. Clin Cancer Res. 2015;21:2499-505 pubmed 出版商
  • 免疫印迹; 人类
Lee Y, Kwon S, An J, Kim C, Choi C, Nam D, et al. Increased protein oxidation and decreased expression of nuclear factor E2-related factor 2 protein in skin tissue of patients with diabetes. Clin Exp Dermatol. 2015;40:192-200 pubmed 出版商
Chen Z, Xiao J, Liu H, Yao K, Hou X, Cao Y, et al. Astaxanthin attenuates oxidative stress and immune impairment in D-galactose-induced aging in rats by activating the Nrf2/Keap1 pathway and suppressing the NF-κB pathway. Food Funct. 2020;: pubmed 出版商
Feng L, Zhao F, Liu Q, Peng J, Duan X, Yan P, et al. Role of Nrf2 in Lipopolysaccharide-Induced Acute Kidney Injury: Protection by Human Umbilical Cord Blood Mononuclear Cells. Oxid Med Cell Longev. 2020;2020:6123459 pubmed 出版商
Wang Y, Lian M, Zhou J, Wu S. Brain Dicer1 Is Down-Regulated in a Mouse Model of Alzheimer's Disease Via Aβ42-Induced Repression of Nuclear Factor Erythroid 2-Related Factor 2. Mol Neurobiol. 2020;: pubmed 出版商
Yuan L, Li Q, Bai D, Shang X, Hu F, Chen Z, et al. La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice. Int J Nanomedicine. 2020;15:3415-3431 pubmed 出版商
Zhao X, Shi Y, Zhang D, Tong X, Sun Y, Xue X, et al. Autophagy inducer activates Nrf2-ARE pathway to attenuate aberrant alveolarization in neonatal rats with bronchopulmonary dysplasia. Life Sci. 2020;252:117662 pubmed 出版商
Xu C, Hou B, He P, Ma P, Yang X, Yang X, et al. Neuroprotective Effect of Salvianolic Acid A against Diabetic Peripheral Neuropathy through Modulation of Nrf2. Oxid Med Cell Longev. 2020;2020:6431459 pubmed 出版商
Zheng D, Liu Z, Zhou Y, Hou N, Yan W, Qin Y, et al. Urolithin B, a gut microbiota metabolite, protects against myocardial ischemia/reperfusion injury via p62/Keap1/Nrf2 signaling pathway. Pharmacol Res. 2020;153:104655 pubmed 出版商
Han J, Guo D, Sun X, Wang J, Ouyang J, Gui B. Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells. Sci Rep. 2019;9:9871 pubmed 出版商
Rabbani P, Soares M, Hameedi S, Kadle R, Mubasher A, Kowzun M, et al. Dysregulation of Nrf2/Keap1 Redox Pathway in Diabetes Affects Multipotency of Stromal Cells. Diabetes. 2019;68:141-155 pubmed 出版商
Wijdeven R, van Luijn M, Wierenga Wolf A, Akkermans J, van den Elsen P, Hintzen R, et al. Chemical and genetic control of IFNγ-induced MHCII expression. EMBO Rep. 2018;19: pubmed 出版商
Rabbani P, Zhou A, Borab Z, Frezzo J, Srivastava N, More H, et al. Novel lipoproteoplex delivers Keap1 siRNA based gene therapy to accelerate diabetic wound healing. Biomaterials. 2017;132:1-15 pubmed 出版商
Lee Y, Kwon S, Kim C, Cho H, Nam H, Lee S, et al. Oxidative Damage and Nuclear Factor Erythroid 2-Related Factor 2 Protein Expression in Normal Skin and Keloid Tissue. Ann Dermatol. 2015;27:507-16 pubmed 出版商
Huang C, Deng W, Zhang L, Zhang W, Sun Z. Expression of LC3, LAMP2, KEAP1 and NRF2 in Salivary Adenoid Cystic Carcinoma. Pathol Oncol Res. 2016;22:109-14 pubmed 出版商
Choi C, Kim J, Wee S, Lee J, Nam D, Kim C, et al. Expression of nuclear factor erythroid 2 protein in malignant cutaneous tumors. Arch Plast Surg. 2014;41:654-60 pubmed 出版商
Zhao F, Li K, Zhao L, Liu J, Suo Q, Zhao J, et al. Effect of Nrf2 on rat ovarian tissues against atrazine-induced anti-oxidative response. Int J Clin Exp Pathol. 2014;7:2780-9 pubmed
Huang C, Zhang L, Ma S, Zhao Z, Wang W, He K, et al. Clinical significance of Keap1 and Nrf2 in oral squamous cell carcinoma. PLoS ONE. 2013;8:e83479 pubmed 出版商
Chandiramani N, Wang X, Margeta M. Molecular basis for vulnerability to mitochondrial and oxidative stress in a neuroendocrine CRI-G1 cell line. PLoS ONE. 2011;6:e14485 pubmed 出版商
Lee D, Kuo H, Liu M, Chou C, Xia W, Du Y, et al. KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Mol Cell. 2009;36:131-40 pubmed 出版商
图像
图像 1 :
武汉三鹰 60027-1-Ig 图像 1
The KEAP1 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human KEAP1. This antibody recognizes human, rat antigen. The KEAP1 antibody has been validated for the following applications: IHC, WB, ELISA analysis.
产品信息
目录号 :
60027-1-Ig
AntigenName :
KEAP1
Package :
150UL
价格 :
299美元
Exsists20ul :
20ul trial size available
FullName :
kelch-like ECH-associated protein 1
免疫原 :
重组蛋白
物种 :
人类, 小鼠, 大鼠
宿主 :
小鼠
IsConjugated :
未共轭
AntigenSpecies :
人类
CloneNo :
4G10H9
应用 :
免疫印迹, 免疫组化, IF, CoIP, 酶联免疫吸附测定
Clonlity :
单克隆
抗体亚型 :
IgA
同义词 :
Cytosolic inhibitor of Nrf2, INrf2, KEAP1, Kelch like protein 19, KIAA0132, KLHL19
PrimaryOrSecondary :
Primary
抗体缓冲液 :
PBS含0.1%叠氮化钠和50% 甘油pH值7.3
GenBank登录号 :
BC002930
类别 :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Metabolism;
PurifyMethod :
Thiophilic affinity chromatograph
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
免疫组化1:50;免疫印迹1:2000;
更多信息或购买 :
公司信息
武汉三鹰
武汉市洪山区关山二路关东科技园7-4#,402室
Service@ptglab.com
http://www.ptgcn.com
4006 900 926, 027-87531629 / 027-87531627
公司总部: 美国
Proteintech Group致力于开发针对所有人类蛋白的抗体,我们将这项计划命名为人类抗体组计划。Proteintech Group在科研领域享有良好声誉, 迄今已生产出针对10,000种不同人类蛋白的10,000种抗体。同时,Proteintech Group也提供多种客户订单服务:克隆,表达,多肽合成,多抗及单抗生产,以满足您的不同需求。

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