抗Hsp90甲抗体 | QED Bioscience 11102 产品信息

产品简要

公司名称 :

QED Bioscience

产品类型 :

抗体

产品名称 :

抗Hsp90甲抗体

11102

规格 :

100微克

价格 :

448美元

克隆性 :

单克隆

宿主 :

小鼠

共轭标签 :

未共轭

克隆名称 :

D7alpha

反应物种 :

人类, 小鼠, 大鼠, 鸡, 牛

更多信息或购买 :

QED Bioscience 产品网页

图像

图像 1 :

Immunohistochemistry analysis using Mouse Anti-Hsp90 Monoclonal Antibody, Clone D7alpha (11102). Tissue: colon carcinoma. Species: Human. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 Monoclonal Antibody (11102) at 1:100000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Magnification: 40x. This image was produced using an amplifying IHC wash buffer. The antibody has therefore been diluted more than is recommended for other applications.

图像 2 :

Immunohistochemistry analysis using Mouse Anti-Hsp90 Monoclonal Antibody, Clone D7alpha (11102). Tissue: inflamed colon. Species: Mouse. Fixation: Formalin. Primary Antibody: Mouse Anti-Hsp90 Monoclonal Antibody (11102) at 1:100000 for 12 hours at 4°C. Secondary Antibody: Biotin Goat Anti-Mouse at 1:2000 for 1 hour at RT. Counterstain: Mayer Hematoxylin (purple/blue) nuclear stain at 200 µl for 2 minutes at RT. Localization: Inflammatory cells. Magnification: 40x. Inflammatory cells. This image was produced using an amplifying IHC wash buffer. The antibody has therefore been diluted more than is recommended for other applications.

图像 3 :

Western Blot analysis of Rat cell lysates showing detection of Hsp90 protein using Mouse Anti-Hsp90 Monoclonal Antibody, Clone D7Alpha (11102). Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp90 Monoclonal Antibody (11102) at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT.

产品信息

目录号 :

11102

产品名称 :

抗Hsp90甲抗体

NAME+SKU :

抗Hsp90甲抗体(11102)

产品_TYPE :

抗体

描述 :

抗Hsp90alpha小鼠单克隆抗体

SPECIFICITY SHORT :

Hsp90alpha

物种活性 :

人类, 小鼠, 大鼠, 兔, 牛, 猪, 鸡

靶标名 :

Hsp90甲

UniProt数据库 :

P11501

LOCATION :

细胞质, 黑素体

蛋白名 :

热休克蛋白HSP 90甲

基因名称 :

HSP90AA1

登录号 :

NP_001103255.1

克隆性 :

单克隆

形式 :

液体

浓度 :

Lot Specific

规格1 :

100微克

标价规格1 :

448美元

DISTIRBUTOR价格 :

313.6

SKU号规格1 :

11102

应用 :

免疫印迹, 免疫沉淀

应用INSTRUCTIONS :

Immunoblotting: use at 1-5ug/ml. A band of ~90 kDa is detected. Immunoprecipitation: 5ug on 20ul Protein A-Sepharose + 100ul sample. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Heat-shocked HeLa cell lysate.

宿主 :

小鼠

格式 :

纯化

纯化 :

经免疫亲和层析纯化

抗体亚型 :

IgG1

克隆编号 :

D7alpha

免疫原 :

全长Hsp90纯化来自鸡大脑

研究领域 :

加热休克&压力蛋白

配方 :

PBS, pH值7.4

缓冲液 :

磷酸盐缓冲液

缓冲液pH值 :

pH值7.4

靶标背景 :

Hsp90 and the 94 kDa glucose-regulated protein, Grp94, are major molecular chapeones of the cytosol and endoplasmic reticulum. In mammalian cells, there are at least two Hsp90 isoforms, Hsp90alpha and Hsp90beta, which are encoded by separate genes. All known members of the Hsp90 family are highly conserved, especially in the N-terminal and C-terminal regions. In the absence of stress, Hsp90 is an essential component of cellular processes such as hormone signaling and cell cycle control. Several regulatory proteins such as steroid receptors, cell cycle kinases and p53 have been identified as substrates of Hsp90.

FUNCTION :

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate rUniProtKB:P07900}.

稀释INSTRUCTIONS :

Dilute in PBS or medium which is identical to that used in the assay system.

STORAGE空调 :

This antibody is stable for at least one (1) year at -20C. Avoid repeated freezing and thawing.

特异性 :

This antibody recognizes human, mouse, rat, rabbit, bovine, porcine, and chicken Hsp90alpha (90 kDa).

图像Name_1 :

qed-bioscience-anti-hsp90-alpha-antibody-11102-1.png

应用1 :

免疫组化

图像Name_2 :

qed-bioscience-anti-hsp90-alpha-antibody-11102-2.png

应用2 :

免疫组化

图像Name_3 :

qed-bioscience-anti-hsp90-alpha-antibody-11102-3.png

应用3 :

免疫印迹

更多信息或购买 :

QED Bioscience 产品网页

公司信息

QED Bioscience

10919 Technology Place, Suite C San Diego, CA 92127

info@qedbio.com

http://www.qedbio.com

800-929-2114 858-675-2405

公司总部: 美国

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