产品简要
公司名称 :
QED Bioscience
产品类型 :
抗体
产品名称 :
抗直流-SIGN(CT)抗体
目录 :
18710
规格 :
100微克
价格 :
455美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
图像
图像 1 :
QED Bioscience 18710 图像 1
Immunohistochemistry of DC-SIGN in human lymph node tissue with DC-SIGN antibody at 10 ug/mL.
图像 2 :
QED Bioscience 18710 图像 2
Immunofluorescence of DC-SIGN in Human Lymph Node tissue with DC-SIGN antibody at 20 ug/mL.
产品信息
目录号 :
18710
产品名称 :
抗直流-SIGN(CT)抗体
NAME+SKU :
抗直流-SIGN(CT)抗体(18710)
产品_TYPE :
抗体
描述 :
抗直流-SIGN(CT)兔多克隆抗体
SPECIFICITY SHORT :
直流-SIGN(CT)
物种活性 :
人类
靶标名 :
直流-SIGN(CT)
UniProt数据库 :
Q9NNX6
LOCATION :
[Isoform 1]: Cell membrane , Single-pass type II membrane protein , Single-pass type II membrane protein , Single-pass type II membrane protein , Single-pass type II membrane protein , Single-pass type II membrane protein
蛋白名 :
CD209抗原
别称 :
C-type lectin domain family 4 member L, Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CD antigen CD209
基因名称 :
CD209
登录号 :
NP_001138365.1
克隆性 :
多克隆
形式 :
液体
浓度 :
Lot Specific
规格1 :
100微克
标价规格1 :
455美元
DISTIRBUTOR价格 :
318.5
SKU号规格1 :
18710
应用 :
免疫印迹
应用INSTRUCTIONS :
Immunoblotting: use at 1-2 ug/ml. In immunoblots, a band of 44 kD is detected. Positive control: Human placenta tissue lysate.
宿主 :
格式 :
纯化
纯化 :
经免疫亲和层析纯化
免疫原 :
Peptide corresponding to aa 384-404 of human DC-SIGN.
研究领域 :
传染病学
配方 :
PBS, pH值7.4
缓冲液 :
磷酸盐缓冲液
缓冲液pH值 :
pH值7.4
FUNCTION :
Pathogen-rPubMed:11859097}.; On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells. {PubMed:10721995, PubMed:11017109, PubMed:12574325}.; (Microbial infection) Acts as an attachment receptor for HIV-1 and HIV-2. {PubMed:11799126, PubMed:12502850, PubMed:1518869}.; (Microbial infection) Acts as an attachment receptor for Ebolavirus. {PubMed:12502850, PubMed:12504546}.; (Microbial infection) Acts as an attachment receptor for Cytomegalovirus. {PubMed:12433371, PubMed:22496863}.; (Microbial infection) Acts as an attachment receptor for HCV. {PubMed:15371595, PubMed:16816373}.; (Microbial infection) Acts as an attachment receptor for Dengue virus. {PubMed:12682107}.; (Microbial infection) Acts as an attachment receptor for Measles virus. {PubMed:16537615}.; (Microbial infection) Acts as an attachment receptor for Herpes simplex virus 1. {PubMed:18796707}.; (Microbial infection) Acts as an attachment receptor for Influenzavirus A. {PubMed:21191006}.; (Microbial infection) Acts as an attachment receptor for SARS-CoV. {PubMed:15140961}.; (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus. {PubMed:24623090}.; (Microbial infection) Acts as an attachment receptor for Lassa virus (PubMed:23966408). Acts as an attachment receptor for Marburg virusn. {PubMed:15479853}.; (Microbial infection) Acts as an attachment receptor for Respiratory syncytial virus. {PubMed:22090124}.; (Microbial infection) Acts as an attachment receptor for Rift valley fever virus and uukuniemi virus. {PubMed:21767814}.; (Microbial infection) Acts as an attachment receptor for West-nile virus. {PubMed:16415006}.; (Microbial infection) Probably rPubMed:16092920, PubMed:16379498, PubMed:21203928}.
稀释INSTRUCTIONS :
Dilute in PBS or medium which is identical to that used in the assay system.
STORAGE空调 :
This antibody is stable for at least one (1) year at -20C. Can be stored at 4C for short-term use.
特异性 :
This antibody recognizes an epitope at the C-terminus of human DC-SIGN, a dendritic cell receptor that can capture and transport HIV from mucosal areas to remote lymph nodes where HIV is then transferred to CD4 T lymphocytes. Multiple strains of HIV-1, HIV-2, and SIV bind to dendritic cells via DC-SIGN. DC-SIGN is expressed in mucosal tissues, placenta, small intestine, and rectum.
图像Name_1 :
qed-bioscience-anti-dc-sign-ct-antibody-18710-1.jpg
应用1 :
免疫印迹
图像Name_2 :
qed-bioscience-anti-dc-sign-ct-antibody-18710-2.jpg
应用2 :
免疫组化
图像Name_3 :
qed-bioscience-anti-dc-sign-ct-antibody-18710-3.jpg
应用3 :
IF
更多信息或购买 :
公司信息
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com
800-929-2114 858-675-2405
公司总部: 美国