产品简要
公司名称 :
QED Bioscience
产品类型 :
抗体
产品名称 :
Anti-Elk-1 (Phospho-Ser383) Antibody
目录 :
43004
规格 :
100微升
价格 :
345美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
更多信息或购买 :
产品信息
目录号 :
43004
产品名称 :
Anti-Elk-1 (Phospho-Ser383) Antibody
NAME+SKU :
Anti-Elk-1 (Phospho-Ser383) Antibody (43004)
产品_TYPE :
抗体
描述 :
Anti-Elk-1 (Phospho-Ser383) Rabbit Polyclonal Antibody
SPECIFICITY SHORT :
Elk-1 (Phospho-Ser383)
物种活性 :
人类, 小鼠, 大鼠
靶标名 :
Elk-1 (Phospho-Ser383)
靶抗原修饰 :
磷酸化ser383
UniProt数据库 :
P19419
LOCATION :
Nucleus.
蛋白名 :
ETS domain-containing protein Elk-1
基因名称 :
ELK1
克隆性 :
多克隆
形式 :
液体
浓度 :
1.0毫克/毫升
规格1 :
100微升
标价规格1 :
345美元
DISTIRBUTOR价格 :
241.5
SKU号规格1 :
43004
应用 :
免疫印迹, 免疫组化
应用INSTRUCTIONS :
Western blotting: use at dilution of 1:500- 1:1,000. A band of ~47kDa is detected.
Immunohistochemistry: use at dilution of 1:50- 1:100.
These are recommended working dilutions. Enduser should determine optimal dilutions for their applications.
宿主 :
兔
格式 :
纯化
纯化 :
经免疫亲和层析纯化
免疫原 :
Peptide sequence that includes phosphorylation site of serine 383 (T-L-S(p)-P-I) derived from human Elk-1 and conjugated to KLH.
研究领域 :
磷酸化特异性抗体
配方 :
PBS (without Mg2 and Ca2 ), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
缓冲液 :
磷酸盐缓冲液
缓冲液pH值 :
pH值7.4
缓冲液抗MICROBIAL :
0.02% 叠氮化钠
缓冲液CRYOPRESERVATIVE :
50% 甘油
靶标背景 :
Elk-1 is a member of the Ets family of transcription factors and the ternary complex factor (TCF) subfamily. Proteins of that subfamily form a ternary complex by binding to the serum response factor and the serum response element in the promoter of the c-fos proto oncogene. Elk-1 protein is a nuclear target for the ras-raf-MAPK signaling cascade.
FUNCTION :
Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity). {UniProtKB:A4GTP4, PubMed:1630903, PubMed:7889942}.
稀释INSTRUCTIONS :
Dilute in PBS or medium that is identical to that used in the assay system.
STORAGE空调 :
This antibody is stable for at least one (1) year at -20C. Can be stored at 4C for short-term use.
特异性 :
This antibody detects endogenous human, mouse, and rat Elk-1 only when phosphorylated at serine 383.
更多信息或购买 :
公司信息
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com800-929-2114 858-675-2405
公司总部: 美国