产品简要
公司名称 :
QED Bioscience
产品类型 :
抗体
产品名称 :
Anti-Tau Antibody
目录 :
57012
规格 :
100微克
价格 :
566美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
反应物种 :
人类
更多信息或购买 :
QED Bioscience 产品网页
图像
图像 1 :
QED Bioscience 57012 图像 1
Dot Blot analysis using Mouse Anti-Tau Monoclonal Antibody, Clone 1D5 (57012). Tissue: Recombinant Protein. Species: Human. Primary Antibody: Mouse Anti-Tau Monoclonal Antibody (57012) at 1:1000 for 2 hours at RT with shaking. Secondary Antibody: Goat anti-mouse IgG:HRP at 1:5000 for 1 hour at RT with shaking.
图像 2 :
QED Bioscience 57012 图像 2
munocytochemistry/Immunofluorescence analysis using Mouse Anti-Tau Monoclonal Antibody, Clone 1D5 (57012). Tissue: iPSC-derived neurons. Species: Human. Fixation: 4% PFA. Primary Antibody: Mouse Anti-Tau Monoclonal Antibody (57012) at 1:100 for Overnight at 4°C. Counterstain: DAPI at 1:5000 for 5 minutes at RT in the dark. Magnification: 40X. Courtesy of: Francesco Paonessa.
图像 3 :
QED Bioscience 57012 图像 3
Western Blot analysis of Human Breast Cancer Cell line and Mouse Brain showing detection of Tau protein using Mouse Anti-Tau Monoclonal Antibody, Clone 1D5 (57012). Lane 1: MW Marker. Lane 2: Human T-47d (10ug). Lane 3: Mouse Brain (20ug). Block: 5% Skim Milk powder in TBST. Primary Antibody: Mouse Anti-Tau Monoclonal Antibody (57012) at 1:1000 for 2 hours at RT with shaking. Secondary Antibody: Goat anti-mouse IgG:HRP at 1:5000 for 1 hour at RT with shaking. Color Development: Chemiluminescent for HRP (Moss) for 5 min in RT.
产品信息
目录号 :
57012
产品名称 :
Anti-Tau Antibody
NAME+SKU :
Anti-Tau Antibody (57012)
产品_TYPE :
抗体
描述 :
Anti-Tau Mouse Monoclonal Antibody
SPECIFICITY SHORT :
Tau
物种活性 :
人类, 小鼠大鼠
靶标名 :
Tau
UniProt数据库 :
P10636
LOCATION :
Cytoplasm, cytosol , Cell membrane , Cytoplasm, cytoskeleton , Cell projection, axon , Cell projection, dendrite , Secreted
蛋白名 :
Microtubule-associated protein tau
别称 :
Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau
基因名称 :
MAPT
克隆性 :
单克隆
形式 :
液体
浓度 :
1.0毫克/毫升
规格1 :
100微克
标价规格1 :
566美元
DISTIRBUTOR价格 :
396.2
SKU号规格1 :
57012
应用 :
免疫印迹
应用INSTRUCTIONS :
Immunoblotting: use at 1-5ug/ml. A band of ~45.8kDa is detected.
宿主 :
小鼠
免疫原 :
Full-length recombinant human Tau441 (2N4R) P301S mutant protein pre-formed fibrils. In humans, mutation P301S gives rise to early-onset dementia.
配方 :
PBS, pH值7.4, 0.09% 叠氮化钠, 50% 甘油
缓冲液 :
磷酸盐缓冲液
缓冲液pH值 :
pH值7.4
缓冲液抗MICROBIAL :
0.09% 叠氮化钠
缓冲液CRYOPRESERVATIVE :
50% 甘油
FUNCTION :
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. {PubMed:21985311, PubMed:32961270}.
STORAGE空调 :
This antibody is stable for 1 month at 4°C or one year at -20°C. Avoid multiple freeze-thaw cycles.
特异性 :
This antibody recognizes human, mouse, and rat Tau.
图像Name_1 :
qed-bioscience-anti-tau-antibody-57012-1.png
应用1 :
DB
图像Name_2 :
qed-bioscience-anti-tau-antibody-57012-2.png
应用2 :
IF
图像Name_3 :
qed-bioscience-anti-tau-antibody-57012-3.png
应用3 :
免疫印迹
更多信息或购买 :
QED Bioscience 产品网页
公司信息
QED Bioscience
10919 Technology Place, Suite C San Diego, CA 92127
info@qedbio.com
http://www.qedbio.com
800-929-2114 858-675-2405
公司总部: 美国