产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类v-erb-b2成红细胞白血病病毒致瘤基因2/Her2多聚组氨酸标签蛋白, CF
目录 :
10126-ER-050
规格 :
50微克
价格 :
400美元
更多信息或购买 :
文章摘录数: 3
参考文献
Yang Y, Yang H, Alcaina Y, Puc J, Birt A, Vedvyas Y, et al. Inducible expression of interleukin-12 augments the efficacy of affinity-tuned chimeric antigen receptors in murine solid tumor models. Nat Commun. 2023;14:2068 pubmed 出版商
Shaimerdenova M, Ayupova T, Bekmurzayeva A, Sypabekova M, Ashikbayeva Z, Tosi D. Spatial-Division Multiplexing Approach for Simultaneous Detection of Fiber-Optic Ball Resonator Sensors: Applications for Refractometers and Biosensors. Biosensors (Basel). 2022;12: pubmed 出版商
Liu Y, Lee A, Nguyen A, Maynard J. An antibody Fc engineered for conditional antibody-dependent cellular cytotoxicity at the low tumor microenvironment pH. J Biol Chem. 2022;298:101798 pubmed 出版商
图像
图像 1 :
安迪生物R&D 10126-ER-050 图像 1
Recombinant Human ErbB2/Her2 His-tag Protein Bioactivity
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
10126-ER
SKU号 :
10126-ER-050
产品名称 :
重组人类v-erb-b2成红细胞白血病病毒致瘤基因2/Her2多聚组氨酸标签蛋白, CF
描述 :
The Recombinant Human ErbB2/Her2 His-tag Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human ErbB2/Her2 His-tag Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
v-erb-b2成红细胞白血病病毒致瘤基因2/Her2
类别 :
蛋白和酶
单位尺寸 :
50微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
93-108 kDa, under reducing conditions
理论上的分子量 :
70 kDa
功能细节 :
Measured by its ability to block anti-ErbB2 mediated inhibition of SK-BR-3 human breast cancer cell proliferation. Brodowicz, T. et al . (1997) Int. J. Cancer 73 :875. The ED50 for this effect is 0.3-1.2 µg/mL in the presence of 0.6 µg/mL Human ErbB2/Her2 Antibody (Trastuzumab, Catalog # MAB9589 ).
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P04626-1
应用 :
Bioactivity
来源 :
HEK293-derived Recombinant Human ErbB2/Her2 His-tag Protein
美元 :
400美元
别名 :
CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, Neu Oncogene, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGL, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.