产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
Recombinant Human Endoglin/CD105 Protein
目录 :
1097-EN-025
规格 :
25微克
价格 :
394美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 10
参考文献
Haarmann A, Zimmermann L, Bieber M, Silwedel C, Stoll G, Schuhmann M. Regulation and Release of Vasoactive Endoglin by Brain Endothelium in Response to Hypoxia/Reoxygenation in Stroke. Int J Mol Sci. 2022;23: pubmed 出版商
Park E, Kim S, Yao D, Savarraj J, Choi H, Chen P, et al. Soluble Endoglin Stimulates Inflammatory and Angiogenic Responses in Microglia That Are Associated with Endothelial Dysfunction. Int J Mol Sci. 2022;23: pubmed 出版商
Pérez Roque L, Núñez Gómez E, Rodriguez Barbero A, Bernabeu C, Lopez Novoa J, Pericacho M. Pregnancy-Induced High Plasma Levels of Soluble Endoglin in Mice Lead to Preeclampsia Symptoms and Placental Abnormalities. Int J Mol Sci. 2020;22: pubmed 出版商
Gallardo Vara E, Gamella Pozuelo L, Pérez Roque L, Bartha J, García Palmero I, Casal J, et al. Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4. Cells. 2020;9: pubmed 出版商
Gallardo Vara E, Ruiz Llorente L, Casado Vela J, Ruiz Rodríguez M, Lopez Andres N, Pattnaik A, et al. Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners. Cells. 2019;8: pubmed 出版商
Walker D, Lue L, Beach T, Tooyama I. Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin. Cells. 2019;8: pubmed 出版商
Ruiz Remolina L, Ollauri Ibáñez C, Pérez Roque L, Núñez Gómez E, Perez Barriocanal F, Lopez Novoa J, et al. Circulating soluble endoglin modifies the inflammatory response in mice. PLoS ONE. 2017;12:e0188204 pubmed 出版商
Olsen O, Wader K, Misund K, Våtsveen T, Rø T, Mylin A, et al. Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin. Blood Cancer J. 2014;4:e196 pubmed 出版商
Rossi E, Sanz Rodriguez F, Eleno N, Düwell A, Blanco F, Langa C, et al. Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration. Blood. 2013;121:403-15 pubmed 出版商
Hawinkels L, Kuiper P, Wiercinska E, Verspaget H, Liu Z, Pardali E, et al. Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis. Cancer Res. 2010;70:4141-50 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
1097-EN
SKU号 :
1097-EN-025
产品名称 :
Recombinant Human Endoglin/CD105 Protein
描述 :
The Recombinant Human Endoglin/CD105 Protein from R&D Systems is derived from NS0. The Recombinant Human Endoglin/CD105 Protein has been validated for the following applications: Bioactivity.
靶标 :
Endoglin/CD105
类别 :
蛋白和酶
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
共轭标签 :
未共轭
纯度 :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
75-85 kDa, reducing conditions
理论上的分子量 :
61 kDa
基因符号 :
ENG
功能细节 :
Measured by its ability to inhibit BMP-10-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 0.06-0.36 µg/mL in the presence of 100 ng/mL of Recombinant Human BMP-10 (Catalog # 2926-BP ).
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q5T9C0
应用 :
Bioactivity
来源 :
NS0-derived Recombinant Human Endoglin/CD105 Protein
extended description :
A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!
美元 :
394美元
产品细节 :
A New rh Endoglin is Available! It has ~100 fold better TGFbRI binding activity and has a Fc tag!
别名 :
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, ENG, HHT1FLJ41744, ORW, ORW1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.