产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类PDGF-CC蛋白
目录 :
1687-CC-025
规格 :
25微克
价格 :
396美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 13
参考文献
Akiyama T, Yasuda T, Uchihara T, Yasuda Yoshihara N, Tan B, Yonemura A, et al. Stromal Reprogramming through Dual PDGFRα/β Blockade Boosts the Efficacy of Anti-PD-1 Immunotherapy in Fibrotic Tumors. Cancer Res. 2023;83:753-770 pubmed 出版商
Li Q, Ming Y, Jia H, Wang G. Poricoic acid A suppresses TGF-β1-induced renal fibrosis and proliferation via the PDGF-C, Smad3 and MAPK pathways. Exp Ther Med. 2021;21:289 pubmed 出版商
Yamamoto Y, Mukai A, Ikushima T, Urata Y, Kinoshita S, Hamuro J, et al. Pluripotent epigenetic regulator OBP-801 maintains filtering blebs in glaucoma filtration surgery model. Sci Rep. 2020;10:20936 pubmed 出版商
López Bellido R, Puig S, Huang P, Tsai C, Turner H, Galko M, et al. Growth factor signaling regulates mechanical nociception in flies and vertebrates. J Neurosci. 2019;: pubmed 出版商
Mahjour F, Dambal V, Shrestha N, Singh V, Noonan V, Kantarci A, et al. Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB. Oncogenesis. 2019;8:34 pubmed 出版商
Mamer S, Chen S, Weddell J, Palasz A, Wittenkeller A, Kumar M, et al. Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics. Sci Rep. 2017;7:16439 pubmed 出版商
He H, Kuriyan A, Su C, Mahabole M, Zhang Y, Zhu Y, et al. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3. Sci Rep. 2017;7:43736 pubmed 出版商
Seki T, Hosaka K, Lim S, Fischer C, Honek J, Yang Y, et al. Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat. Nat Commun. 2016;7:12152 pubmed 出版商
Hayes B, Riehle K, Shimizu Albergine M, Bauer R, Hudkins K, Johansson F, et al. Activation of platelet-derived growth factor receptor alpha contributes to liver fibrosis. PLoS ONE. 2014;9:e92925 pubmed 出版商
Son D, Na Y, Hwang E, Seok S. Platelet-derived growth factor-C (PDGF-C) induces anti-apoptotic effects on macrophages through Akt and Bad phosphorylation. J Biol Chem. 2014;289:6225-35 pubmed 出版商
Ball S, Bayley C, Shuttleworth C, Kielty C. Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells. Biochem J. 2010;427:29-40 pubmed 出版商
Crawford Y, Kasman I, Yu L, ZHONG C, Wu X, Modrusan Z, et al. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell. 2009;15:21-34 pubmed 出版商
Wågsäter D, Zhu C, Björck H, Eriksson P. Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression. Atherosclerosis. 2009;202:415-23 pubmed 出版商
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
1687-CC
SKU号 :
1687-CC-025
产品名称 :
重组人类PDGF-CC蛋白
描述 :
The Recombinant Human PDGF-CC Protein from R&D Systems is derived from E. coli. The Recombinant Human PDGF-CC Protein has been validated for the following applications: Bioactivity.
靶标 :
PDGF-CC
类别 :
蛋白和酶
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
物种 :
人类
理论上的分子量 :
13.4 kDa (monomer)
基因符号 :
PDGFC
功能细节 :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 70-350 ng/mL.
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_057289
应用 :
Bioactivity
来源 :
E. coli-derived Recombinant Human PDGF-CC Protein
美元 :
396美元
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.