重组人类丝氨酸蛋白酶抑制剂E1/PAI-1蛋白, CF | 安迪生物R&D 1786-PI-010 产品信息

产品简要

公司名称 :

安迪生物R&D

产品类型 :

蛋白

产品名称 :

重组人类丝氨酸蛋白酶抑制剂E1/PAI-1蛋白, CF

1786-主要研究者

规格 :

10微克

价格 :

396美元

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 9

参考文献
Infante A, RodrÃguez C. Secretome analysis of in vitro aged human mesenchymal stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis. Sci Rep. 2018;8:4632 pubmed 出版商
MikuÅ‚a Pietrasik J, Uruski P, SosiÅ„ska P, Maksin K, Piotrowska Kempisty H, KuciÅ„ska M, et al. Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases. Cell Death Dis. 2016;7:e2565 pubmed 出版商
Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, et al. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med. 2015;212:905-25 pubmed 出版商
Santhekadur P, Akiel M, Emdad L, Gredler R, Srivastava J, Rajasekaran D, et al. Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGF? signaling. FEBS Open Bio. 2014;4:353-61 pubmed 出版商
Krstic D, Rodríguez M, Knuesel I. Regulated proteolytic processing of Reelin through interplay of tissue plasminogen activator (tPA), ADAMTS-4, ADAMTS-5, and their modulators. PLoS ONE. 2012;7:e47793 pubmed 出版商
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed 出版商
Huang M, Patel K, Taub D, Longo D, Goetzl E. Human CD4- 8- T cells are a distinctive immunoregulatory subset. FASEB J. 2010;24:2558-66 pubmed 出版商
Szabo R, Hobson J, List K, Molinolo A, Lin C, Bugge T. Potent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity. J Biol Chem. 2008;283:29495-504 pubmed 出版商
Memari N, Jiang W, Diamandis E, Luo L. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biol Chem. 2007;388:427-35 pubmed

图像

图像 1 :

Recombinant Human Serpin E1/PAI-1 Protein Enzyme Activity

产品信息

品牌 :

R&D Systems, a Bio-Techne Brand

catalog number base :

1786-主要研究者

SKU号 :

1786-主要研究者

产品名称 :

重组人类丝氨酸蛋白酶抑制剂E1/PAI-1蛋白, CF

描述 :

The Recombinant Human Serpin E1/PAI-1 Protein, CF from R&D Systems is derived from Sf 21 (stably transfected). The Recombinant Human Serpin E1/PAI-1 Protein, CF has been validated for the following applications: Inhibition Activity.

靶标 :

丝氨酸蛋白酶抑制剂E1/PAI-1

类别 :

蛋白和酶

单位尺寸 :

10微克

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in Sodium Acetate, NaCl and CHAPS.

共轭标签 :

未共轭

纯度 :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

物种 :

人类

观察到的分子量 :

43 kDa, reducing conditions

理论上的分子量 :

44 kDa

基因符号 :

SERPINE1

功能细节 :

Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The IC50 value is 13 nM, as measured under the described conditions.

内毒素说明 :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P05121

应用 :

抑制作用活性

来源 :

Sf 21 (stably transfected)-derived Recombinant Human Serpin E1/PAI-1 Protein

美元 :

396美元

别名 :

Endothelial plasminogen activator inhibitor, Nexin, PAI1, PAI-1, PAI1PAI-1, PAISerpin E1, PLANH1, PLANH1plasminogen activator inhibitor 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.