产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类半乳凝素9蛋白, CF
目录 :
2045-GA-050
规格 :
50 ug (also 1 mg)
价格 :
423美元
更多信息或购买 :
文章摘录数: 6
参考文献
Eriksen L, Nielsen M, Laursen T, Deleuran B, Vilstrup H, St xf8 y S. Early loss of T lymphocyte 4-1BB receptor expression is associated with higher short-term mortality in alcoholic hepatitis. PLoS ONE. 2021;16:e0255574 pubmed 出版商
Gonçalves Silva I, Ruegg L, Gibbs B, Bardelli M, Fruehwirth A, Varani L, et al. The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells. Oncoimmunology. 2016;5:e1195535 pubmed 出版商
Leskela S, Serrano A, de la Fuente H, Rodríguez Muñoz A, Ramos Levi A, Sampedro Nuñez M, et al. Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells. PLoS ONE. 2015;10:e0123938 pubmed 出版商
Ungerer C, Quade Lyssy P, Radeke H, Henschler R, Konigs C, Köhl U, et al. Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations. Stem Cells Dev. 2014;23:755-66 pubmed 出版商
Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Müller I. Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation. Eur J Immunol. 2013;43:2741-9 pubmed 出版商
Vaitaitis G, Wagner D. Galectin-9 controls CD40 signaling through a Tim-3 independent mechanism and redirects the cytokine profile of pathogenic T cells in autoimmunity. PLoS ONE. 2012;7:e38708 pubmed 出版商
图像
图像 1 :
安迪生物R&D 2045-GA-050 图像 1
Recombinant Human Galectin-9 Protein SDS-PAGE
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
2045-GA
SKU号 :
2045-GA-050
产品名称 :
重组人类半乳凝素9蛋白, CF
描述 :
The Recombinant Human Galectin-9 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Galectin-9 Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
半乳凝素9
类别 :
蛋白和酶
单位尺寸 :
50 ug (also 1 mg)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in MOPS, NaCl, EDTA, DTT and Trehalose.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
物种 :
人类
观察到的分子量 :
34 kDa, reducing conditions
理论上的分子量 :
35.8 kDa
功能细节 :
Measured by its ability to induce apoptosis of Jurkat human acute T cell leukemia cells. Lu, L.H.  et al . (2007) J. Biochem. 141 :157. The ED50 for this effect is 1-5 µg/mL. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Galectin-9 at 500 ng/mL can bind Recombinant Human TIM-3 Fc Chimera (Catalog # 2365-TM ) with an apparent Kd 30 nM.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
BAA31542
应用 :
Bioactivity
来源 :
E. coli-derived Recombinant Human Galectin-9 Protein
美元 :
423美元
别名 :
ecalectin, gal-9, GAL9, galectin 9, galectin-9, Galectin9, HUAT, lectin, galactoside-binding, soluble, 9, LGALS9, LGALS9A, MGC117375, MGC125973, MGC125974, Tumor antigen HOM-HD-21, urate transporter/channel protein
储存 :
12 months from date of receipt, <= -20 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.