参考文献 |
---|
Abasiyanik M, Wolfe K, Van Phan H, Lin J, Laxman B, White S, et al. Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes. Nat Commun. 2020;11:2607 pubmed 出版商
|
Kanasugi J, Hanamura I, Ota A, Karnan S, Lam V, Mizuno S, et al. Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells. Cancer Sci. 2020;111:1663-1675 pubmed 出版商
|
Mang T, Lindemann S, Gigout A. Increasing the Medium Osmolarity Reduces the Inflammatory Status of Human OA Chondrocytes and Increases Their Responsiveness to GDF-5. Int J Mol Sci. 2020;21: pubmed 出版商
|
Hook J, Cao M, Weng K, Kinnare N, Moreland J. Mycobacterium tuberculosis Lipoarabinomannan Activates Human Neutrophils via a TLR2/1 Mechanism Distinct from Pam3CSK4. J Immunol. 2020;204:671-681 pubmed 出版商
|
Stefka A, Johnson D, Rosebeck S, Park J, Nakamura Y, Jakubowiak A. Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models. Cancer Med. 2020;9:324-334 pubmed 出版商
|
Lee J, Zhong X, Lee J, Surh Y, Na H. 15-Keto prostaglandin E2 induces heme oxygenase-1 expression through activation of Nrf2 in human colon epithelial CCD 841 CoN cells. Arch Biochem Biophys. 2020;679:108162 pubmed 出版商
|
Parashar D, Geethadevi A, Aure M, Mishra J, George J, Chen C, et al. miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer. Cell Rep. 2019;29:4389-4406.e10 pubmed 出版商
|
De Silva D, Zhang Z, Liu Y, Parker J, Xu C, Cai L, et al. Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen. Sci Rep. 2019;9:18637 pubmed 出版商
|
Sun X, Qu Q, Lao Y, Zhang M, Yin X, Zhu H, et al. Tumor suppressor HIC1 is synergistically compromised by cancer-associated fibroblasts and tumor cells through the IL-6/pSTAT3 axis in breast cancer. BMC Cancer. 2019;19:1180 pubmed 出版商
|
Stumpf A, Brandstetter T, Hübner J, Rühe J. Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum. PLoS ONE. 2019;14:e0225525 pubmed 出版商
|
Xu X, Fukui H, Ran Y, Wang X, Inoue Y, Ebisudani N, et al. The Link between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues. Mediators Inflamm. 2019;2019:7859460 pubmed 出版商
|
Uyama N, Tsutsui H, Wu S, Yasuda K, Hatano E, Qin X, et al. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation. Sci Rep. 2019;9:17558 pubmed 出版商
|
Ko J, Lian W, Tsai T, Chen Y, Hsieh C, Kuo C, et al. MicroRNA-29a Mitigates Subacromial Bursa Fibrosis in Rotator Cuff Lesion with Shoulder Stiffness. Int J Mol Sci. 2019;20: pubmed 出版商
|
Gong Y, Liu H, Tao L. Cajanonic acid A regulates the ratio of Th17/Treg via inhibition of expression of IL-6 and TGF-β in insulin-resistant HepG2 cells. Biosci Rep. 2019;39: pubmed 出版商
|
Liu Z, Easson G, Zhao J, Makki N, Ahituv N, Hilton M, et al. Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice. PLoS Genet. 2019;15:e1008096 pubmed 出版商
|
Grajcarek J, Monlong J, Nishinaka Arai Y, Nakamura M, Nagai M, Matsuo S, et al. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nat Commun. 2019;10:4856 pubmed 出版商
|
Moonen C, de Vries T, Rijkschroeff P, Poubelle P, Nicu E, Loos B. The Possible Role of Neutrophils in the Induction of Osteoclastogenesis. J Immunol Res. 2019;2019:8672604 pubmed 出版商
|
Wonderlich E, Subramanian K, Cox B, Wiegand A, Lackman Smith C, Bale M, et al. Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals. PLoS Pathog. 2019;15:e1008074 pubmed 出版商
|
Liang C, Li J, Lu C, Xie D, Liu J, Zhong C, et al. HIF1α inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis. Nat Commun. 2019;10:4579 pubmed 出版商
|
Jang H, Lim H, Park E, Lee S, Lee S, Lee S, et al. STAT3-inhibitory activity of sesquiterpenoids and diterpenoids from Curcuma phaeocaulis. Bioorg Chem. 2019;93:103267 pubmed 出版商
|
Yang Y, Wang W, Chang H, Han Z, Yu X, Zhang T. Reciprocal regulation of miR-206 and IL-6/STAT3 pathway mediates IL6-induced gefitinib resistance in EGFR-mutant lung cancer cells. J Cell Mol Med. 2019;23:7331-7341 pubmed 出版商
|
Horrevorts S, Stolk D, van de Ven R, Hulst M, Van het Hof B, Duinkerken S, et al. Glycan-Modified Apoptotic Melanoma-Derived Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination. Cancers (Basel). 2019;11: pubmed 出版商
|
McKenzie M, Ghisi M, Oxley E, Ngo S, Cimmino L, Esnault C, et al. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. Cell Stem Cell. 2019;25:258-272.e9 pubmed 出版商
|
Nasri M, Ritter M, Mir P, Dannenmann B, Aghaallaei N, Amend D, et al. CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients. Haematologica. 2019;: pubmed 出版商
|
Mishra A, Dingli D. Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells. Leukemia. 2019;: pubmed 出版商
|
Mair B, Tomic J, Masud S, Tonge P, Weiss A, Usaj M, et al. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 2019;27:599-615.e12 pubmed 出版商
|
Kristoff J, Palma M, Garcia Bates T, Shen C, Sluis Cremer N, Gupta P, et al. Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1. EBioMedicine. 2019;43:295-306 pubmed 出版商
|
Wei C, Yang C, Wang S, Shi D, Zhang C, Lin X, et al. Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis. Mol Cancer. 2019;18:64 pubmed 出版商
|
Sun S, Zhang X, Xu M, Zhang F, Tian F, Cui J, et al. Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes. Cell Death Dis. 2019;10:274 pubmed 出版商
|
Hochdörfer T, Winkler C, Pardali K, Mjösberg J. Expression of c-Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells. Eur J Immunol. 2019;49:884-893 pubmed 出版商
|
van Bastelaar J, Granzier R, van Roozendaal L, van Kuijk S, Lerut A, Beets G, et al. Analysis of TNF-α and interleukin-6 in seroma of patients undergoing mastectomy with or without flap fixation: is there a predictive value for seroma formation and its sequelae?. Surg Oncol. 2019;28:36-41 pubmed 出版商
|
Suga M, Kondo T, Imamura K, Shibukawa R, Okanishi Y, Sagara Y, et al. Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I. Stem Cell Res. 2019;36:101406 pubmed 出版商
|
Doh K, Kim B, Kim K, Chung B, Yang C. Effects of resveratrol on Th17 cell-related immune responses under tacrolimus-based immunosuppression. BMC Complement Altern Med. 2019;19:54 pubmed 出版商
|
Qin X, Liu M, Zhang S, Wang C, Zhang T. The role of IL-36γ and its regulation in eosinophilic inflammation in allergic rhinitis. Cytokine. 2019;117:84-90 pubmed 出版商
|
Xu H, Xu S, Xie S, Zhang Y, Yang J, Zhang W, et al. MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway. elife. 2019;8: pubmed 出版商
|
Potirat P, Wattanapanitch M, Viprakasit V, Kheolamai P, Issaragrisil S. An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling. Stem Cell Res. 2019;34:101344 pubmed 出版商
|
Ahmed T, Adamopoulos C, Karoulia Z, Wu X, Sachidanandam R, Aaronson S, et al. SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors. Cell Rep. 2019;26:65-78.e5 pubmed 出版商
|
Yamamoto S, Omori K, Mandai H, Nakayama M, Nakagawa S, Kobayashi H, et al. Fungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts. Heliyon. 2018;4:e00979 pubmed 出版商
|
Tomic S, Ilic N, Kokol V, Gruden Movsesijan A, Mihajlović D, Bekić M, et al. Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells. Int J Nanomedicine. 2018;13:6941-6960 pubmed 出版商
|
Charbit Henrion F, Begue B, Sierra A, Hanein S, Stolzenberg M, Li Z, et al. Copy number variations and founder effect underlying complete IL-10Rβ deficiency in Portuguese kindreds. PLoS ONE. 2018;13:e0205826 pubmed 出版商
|
Painuly U, Ramakrishnan V, Kimlinger T, Wellik L, Haug J, Gonsalves W, et al. Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular subgroups of multiple myeloma. Oncotarget. 2018;9:34582-34594 pubmed 出版商
|
Kinchen J, Chen H, Parikh K, Antanaviciute A, Jagielowicz M, Fawkner Corbett D, et al. Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease. Cell. 2018;175:372-386.e17 pubmed 出版商
|
Zhong M, Huang Z, Wang L, Lin Z, Cao Z, Li X, et al. Malignant Transformation of Human Bronchial Epithelial Cells Induced by Arsenic through STAT3/miR-301a/SMAD4 Loop. Sci Rep. 2018;8:13291 pubmed 出版商
|
Jin X, He X, Cao X, Xu P, Xing Y, Sui S, et al. Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice. Haematologica. 2018;103:1627-1634 pubmed 出版商
|
Gong C, Shen J, Fang Z, Qiao L, Feng R, Lin X, et al. Abnormally expressed JunB transactivated by IL-6/STAT3 signaling promotes uveal melanoma aggressiveness via epithelial-mesenchymal transition. Biosci Rep. 2018;38: pubmed 出版商
|
Marwick J, Mills R, Kay O, Michail K, Stephen J, Rossi A, et al. Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation. Cell Death Dis. 2018;9:665 pubmed 出版商
|
Ohno T, Aoki H, Ohno S, Nishihara M, Furusho A, Hiromatsu S, et al. Cytokine Profile of Human Abdominal Aortic Aneurysm: Involvement of JAK/STAT Pathway. Ann Vasc Dis. 2018;11:84-90 pubmed 出版商
|
Beringer A, Thiam N, Molle J, Bartosch B, Miossec P. Synergistic effect of interleukin-17 and tumour necrosis factor-α on inflammatory response in hepatocytes through interleukin-6-dependent and independent pathways. Clin Exp Immunol. 2018;193:221-233 pubmed 出版商
|
Srivastava R, Cornicelli J, MARKHAM B, Bisgaier C. Gemcabene, a first-in-class lipid-lowering agent in late-stage development, down-regulates acute-phase C-reactive protein via C/EBP-δ-mediated transcriptional mechanism. Mol Cell Biochem. 2018;449:167-183 pubmed 出版商
|
Cesana M, Guo M, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, et al. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell. 2018;22:575-588.e7 pubmed 出版商
|
Kotha S, Sun S, Adams A, Hayes B, Phong K, NAGAO R, et al. Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment. PLoS ONE. 2018;13:e0195082 pubmed 出版商
|
Lucifora J, Bonnin M, Aillot L, Fusil F, Maadadi S, Dimier L, et al. Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes. Sci Rep. 2018;8:5390 pubmed 出版商
|
Klaesson A, Grannas K, Ebai T, Heldin J, Koos B, Leino M, et al. Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes. Sci Rep. 2018;8:5400 pubmed 出版商
|
Pei H, He L, Shao M, Yang Z, Ran Y, Li D, et al. Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis. Sci Rep. 2018;8:5273 pubmed 出版商
|
Nagel S, Pommerenke C, Meyer C, Kaufmann M, MacLeod R, Drexler H. Aberrant expression of NKL homeobox gene HLX in Hodgkin lymphoma. Oncotarget. 2018;9:14338-14353 pubmed 出版商
|
Jiang M, Wang Y, Zhang H, Ji Y, Zhao P, Sun R, et al. IL-37 inhibits invasion and metastasis in non-small cell lung cancer by suppressing the IL-6/STAT3 signaling pathway. Thorac Cancer. 2018;9:621-629 pubmed 出版商
|
Napoletano C, Mattiucci S, Colantoni A, Battisti F, Zizzari I, Rahimi H, et al. Anisakis pegreffii impacts differentiation and function of human dendritic cells. Parasite Immunol. 2018;40:e12527 pubmed 出版商
|
Ohsaki A, Miyano Y, Tanaka R, Tanuma S, Kojima S, Tsukimoto M. A Novel Mechanism of γ-Irradiation-Induced IL-6 Production Mediated by P2Y11 Receptor in Epidermal Keratinocytes. Biol Pharm Bull. 2018;41:925-936 pubmed 出版商
|
Fraser H, Safinia N, Grageda N, Thirkell S, Lowe K, Fry L, et al. A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials. Mol Ther Methods Clin Dev. 2018;8:198-209 pubmed 出版商
|
Zheng S, Papalexi E, Butler A, STEPHENSON W, Satija R. Molecular transitions in early progenitors during human cord blood hematopoiesis. Mol Syst Biol. 2018;14:e8041 pubmed 出版商
|
Chen J, Liu X, Munshi M, Xu L, Tsakmaklis N, Demos M, et al. BTKCys481Ser drives ibrutinib resistance via ERK1/2, and protects BTKWild-Type MYD88 mutated cells by a paracrine mechanism. Blood. 2018;: pubmed 出版商
|
Ching C, Gupta S, Li B, Cortado H, Mayne N, Jackson A, et al. Interleukin-6/Stat3 signaling has an essential role in the host antimicrobial response to urinary tract infection. Kidney Int. 2018;93:1320-1329 pubmed 出版商
|
Wilson R, Makuch M, Kienzler A, Varley J, Taylor J, Woodhall M, et al. Condition-dependent generation of aquaporin-4 antibodies from circulating B cells in neuromyelitis optica. Brain. 2018;141:1063-1074 pubmed 出版商
|
Zhang F, Liu G, Li D, Wei C, Hao J. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway. J Immunol. 2018;200:1618-1626 pubmed 出版商
|
Alsaffar H, Martino N, Garrett J, Adam A. Interleukin-6 promotes a sustained loss of endothelial barrier function via Janus kinase-mediated STAT3 phosphorylation and de novo protein synthesis. Am J Physiol Cell Physiol. 2018;314:C589-C602 pubmed 出版商
|
Jalili R, Horecka J, Swartz J, Davis R, Persson H. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies. Proc Natl Acad Sci U S A. 2018;115:E925-E933 pubmed 出版商
|
Schmitt K, Charlins P, Veselinovic M, Kinner Bibeau L, Hu S, Curlin J, et al. Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model. Virology. 2018;515:235-242 pubmed 出版商
|
Choi Y, Park S, Park Y, Park H, Yang K, Heo K. EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells. PLoS ONE. 2018;13:e0190638 pubmed 出版商
|
Radecke S, Schwarz K, Radecke F. Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments. Mol Ther. 2018;26:115-131 pubmed 出版商
|
Palau A, Garz A, Diesch J, Zwick A, Malinverni R, Valero V, et al. Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes. Oncotarget. 2017;8:115002-115017 pubmed 出版商
|
Zhang Q, Yang Z, Han Q, Bai H, Wang Y, Yi X, et al. G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3. Oncotarget. 2017;8:109043-109060 pubmed 出版商
|
Tyzack G, Hall C, Sibley C, Cymes T, Forostyak S, Carlino G, et al. A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models. Nat Commun. 2017;8:1164 pubmed 出版商
|
Wang Y, Mumm J, Herbst R, Kolbeck R, Wang Y. IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression. J Immunol. 2017;199:3316-3325 pubmed 出版商
|
Steinert A, Linas I, Kaya B, Ibrahim M, Schlitzer A, Hruz P, et al. The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models. J Immunol. 2017;199:2570-2584 pubmed 出版商
|
Palpant N, Wang Y, Hadland B, Zaunbrecher R, Redd M, Jones D, et al. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis. Cell Rep. 2017;20:1597-1608 pubmed 出版商
|
Hsu H, Lai M, Lee J, Yen M, Weng T, Chen W, et al. Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling. Sci Rep. 2017;7:5823 pubmed 出版商
|
von Stemann J, Rigas A, Thørner L, Rasmussen D, Pedersen O, Rostgaard K, et al. Prevalence and correlation of cytokine-specific autoantibodies with epidemiological factors and C-reactive protein in 8,972 healthy individuals: Results from the Danish Blood Donor Study. PLoS ONE. 2017;12:e0179981 pubmed 出版商
|
Ye J, Wang Y, Liu X, Li L, Opejin A, Hsueh E, et al. TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy. J Immunol. 2017;199:941-954 pubmed 出版商
|
Zhu B, Chen S, Hu X, Jin X, Le Y, Cao L, et al. Knockout of the Nogo-B Gene Attenuates Tumor Growth and Metastasis in Hepatocellular Carcinoma. Neoplasia. 2017;19:583-593 pubmed 出版商
|
Forcade E, Paz K, Flynn R, Griesenauer B, Amet T, Li W, et al. An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition. JCI Insight. 2017;2: pubmed 出版商
|
Mayati A, Moreau A, Denizot C, Stieger B, Parmentier Y, Fardel O. β2-adrenergic receptor-mediated in vitro regulation of human hepatic drug transporter expression by epinephrine. Eur J Pharm Sci. 2017;106:302-312 pubmed 出版商
|
Wang D, Tang S, Zhang Q. Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway. Oncol Lett. 2017;13:4875-4881 pubmed 出版商
|
Geng J, Yu S, Zhao H, Sun X, Li X, Wang P, et al. The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells. Nat Immunol. 2017;18:800-812 pubmed 出版商
|
Kanamori Y, Murakami M, Sugiyama M, Hashimoto O, Matsui T, Funaba M. Interleukin-1? (IL-1?) transcriptionally activates hepcidin by inducing CCAAT enhancer-binding protein ? (C/EBP?) expression in hepatocytes. J Biol Chem. 2017;292:10275-10287 pubmed 出版商
|
Zhang Z, He Q, Tao Y, Guo J, Xu F, Wu L, et al. Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes. Am J Transl Res. 2017;9:454-465 pubmed
|
Kokubu Y, Yamaguchi T, Kawabata K. In vitro model of cerebral ischemia by using brain microvascular endothelial cells derived from human induced pluripotent stem cells. Biochem Biophys Res Commun. 2017;486:577-583 pubmed 出版商
|
Schwartz J, Clayton K, Mujib S, Zhang H, Rahman A, Liu J, et al. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9. J Immunol. 2017;198:3181-3194 pubmed 出版商
|
He H, Kuriyan A, Su C, Mahabole M, Zhang Y, Zhu Y, et al. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3. Sci Rep. 2017;7:43736 pubmed 出版商
|
Pachori A, Madan M, Nunez Lopez Y, Yi F, Meyer C, Seyhan A. Reduced skeletal muscle secreted frizzled-related protein 3 is associated with inflammation and insulin resistance. Obesity (Silver Spring). 2017;25:697-703 pubmed 出版商
|
Tsukamoto H, Fujieda K, Hirayama M, Ikeda T, Yuno A, Matsumura K, et al. Soluble IL6R Expressed by Myeloid Cells Reduces Tumor-Specific Th1 Differentiation and Drives Tumor Progression. Cancer Res. 2017;77:2279-2291 pubmed 出版商
|
Muhammad J, Nanjo S, Ando T, Yamashita S, Maekita T, Ushijima T, et al. Autophagy impairment by Helicobacter pylori-induced methylation silencing of MAP1LC3Av1 promotes gastric carcinogenesis. Int J Cancer. 2017;140:2272-2283 pubmed 出版商
|
Tanaka M, Tashiro H, Omer B, Lapteva N, Ando J, Ngo M, et al. Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells. Clin Cancer Res. 2017;23:3499-3509 pubmed 出版商
|
Lin C, Liao W, Jian Y, Peng Y, Zhang X, Ye L, et al. CGI-99 promotes breast cancer metastasis via autocrine interleukin-6 signaling. Oncogene. 2017;36:3695-3705 pubmed 出版商
|
Bott A, Erdem N, Lerrer S, Hotz Wagenblatt A, Breunig C, Abnaof K, et al. miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A. Oncotarget. 2017;8:43897-43914 pubmed 出版商
|
Adams R, Burnley R, Valenzano C, Qureshi O, Doyle C, Lumb S, et al. Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling. Sci Rep. 2017;7:37716 pubmed 出版商
|
Oben K, Gachuki B, Alhakeem S, McKenna M, Liang Y, St Clair D, et al. Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1). PLoS ONE. 2017;12:e0169767 pubmed 出版商
|
Elias S, Schmidt A, Kannan V, Andersson J, Tegner J. TGF-? Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner. Front Immunol. 2016;7:603 pubmed 出版商
|
Spicer L, Schütz L, Williams J, Schreiber N, Evans J, Totty M, et al. G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications. Domest Anim Endocrinol. 2017;59:90-99 pubmed 出版商
|
Kerstein A, Schüler S, Cabral Marques O, Fazio J, Häsler R, Muller A, et al. Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis. J Autoimmun. 2017;78:79-91 pubmed 出版商
|
MikuÅ‚a Pietrasik J, Uruski P, SosiÅ„ska P, Maksin K, Piotrowska Kempisty H, KuciÅ„ska M, et al. Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases. Cell Death Dis. 2016;7:e2565 pubmed 出版商
|
Takeshita Y, Obermeier B, Cotleur A, Spampinato S, Shimizu F, Yamamoto E, et al. Effects of neuromyelitis optica-IgG at the blood-brain barrier in vitro. Neurol Neuroimmunol Neuroinflamm. 2017;4:e311 pubmed 出版商
|
Chiche A, Le Roux I, von Joest M, Sakai H, AguÃn S, Cazin C, et al. Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle. Cell Stem Cell. 2017;20:407-414.e4 pubmed 出版商
|
Wang J, Qiao C, Xiao H, Lin Z, Li Y, Zhang J, et al. Structure-based virtual screening and characterization of a novel IL-6 antagonistic compound from synthetic compound database. Drug Des Devel Ther. 2016;10:4091-4100 pubmed 出版商
|
Pomeroy E, Lee L, Lee R, Schirm D, Temiz N, Ma J, et al. Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia. Oncogene. 2017;36:3263-3273 pubmed 出版商
|
Allen S, Chen Y, Madden J, Fournier C, Altemus M, Hiziroglu A, et al. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling. Sci Rep. 2016;6:39190 pubmed 出版商
|
Tyagi R, Parmar R, Patel N. A generic RNA pulsed DC based approach for developing therapeutic intervention against nasopharyngeal carcinoma. Hum Vaccin Immunother. 2017;13:854-866 pubmed 出版商
|
Ji T, Takabayashi H, Mao M, Han X, Xue X, Brazil J, et al. Regulation and function of bone morphogenetic protein signaling in colonic injury and inflammation. Am J Physiol Gastrointest Liver Physiol. 2017;312:G24-G33 pubmed 出版商
|
Tsaousi A, Witte E, Witte K, Röwert Huber H, Volk H, Sterry W, et al. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations. Mediators Inflamm. 2016;2016:4097574 pubmed
|
Ju X, Silveira P, Hsu W, Elgundi Z, Alingcastre R, Verma N, et al. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population. J Immunol. 2016;197:4613-4625 pubmed
|
Bastidas Coral A, Bakker A, Zandieh Doulabi B, Kleverlaan C, Bravenboer N, Forouzanfar T, et al. Cytokines TNF-α, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells. Stem Cells Int. 2016;2016:1318256 pubmed 出版商
|
Mathis T, Housset M, Eandi C, Beguier F, Touhami S, Reichman S, et al. Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-?. Aging Cell. 2017;16:173-182 pubmed 出版商
|
König C, Morch E, Eitner A, Möller C, Turnquist B, Schaible H, et al. Involvement of Spinal IL-6 Trans-Signaling in the Induction of Hyperexcitability of Deep Dorsal Horn Neurons by Spinal Tumor Necrosis Factor-Alpha. J Neurosci. 2016;36:9782-91 pubmed 出版商
|
Pinte S, Caetano B, Le Bras A, Havet C, Villain G, Dernayka R, et al. Endothelial Cell Activation Is Regulated by Epidermal Growth Factor-like Domain 7 (Egfl7) during Inflammation. J Biol Chem. 2016;291:24017-24028 pubmed
|
Titos E, Rius B, López Vicario C, Alcaraz Quiles J, García Alonso V, Lopategi A, et al. Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue. J Immunol. 2016;197:3360-3370 pubmed
|
Doerr N, Wang Y, Kipp K, Liu G, Benza J, Pletnev V, et al. Regulation of Polycystin-1 Function by Calmodulin Binding. PLoS ONE. 2016;11:e0161525 pubmed 出版商
|
Quick L, Young R, Henrich I, Wang X, Asmann Y, Oliveira A, et al. Jak1-STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis. Cancer Res. 2016;76:5337-47 pubmed 出版商
|
Harwardt T, Lukas S, Zenger M, Reitberger T, Danzer D, Übner T, et al. Human Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like Response. PLoS Pathog. 2016;12:e1005748 pubmed 出版商
|
Pinkenburg O, Meyer T, Bannert N, Norley S, Bolte K, Czudai Matwich V, et al. The Human Antimicrobial Protein Bactericidal/Permeability-Increasing Protein (BPI) Inhibits the Infectivity of Influenza A Virus. PLoS ONE. 2016;11:e0156929 pubmed 出版商
|
Ratajewski M, Walczak Drzewiecka A, Gorzkiewicz M, Sałkowska A, Dastych J. Expression of human gene coding ROR?T receptor depends on the Sp2 transcription factor. J Leukoc Biol. 2016;100:1213-1223 pubmed
|
Halpert M, Konduri V, Liang D, Chen Y, Wing J, Paust S, et al. Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7. Stem Cells Dev. 2016;25:774-87 pubmed 出版商
|
Zhong H, Davis A, Ouzounova M, Carrasco R, Chen C, Breen S, et al. A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors. Cancer Res. 2016;76:480-90 pubmed 出版商
|
Huston S, Ngamskulrungroj P, Xiang R, Ogbomo H, Stack D, Li S, et al. Cryptococcus gattii Capsule Blocks Surface Recognition Required for Dendritic Cell Maturation Independent of Internalization and Antigen Processing. J Immunol. 2016;196:1259-71 pubmed 出版商
|
Yoon B, Chung Y, Yoo S, Kawara K, Kim J, Yoo I, et al. Preferential Induction of the T Cell Auxiliary Signaling Molecule B7-H3 on Synovial Monocytes in Rheumatoid Arthritis. J Biol Chem. 2016;291:4048-57 pubmed 出版商
|
Min H, Kim S, Baek S, Woo J, Park J, Cho M, et al. Anthocyanin Extracted from Black Soybean Seed Coats Prevents Autoimmune Arthritis by Suppressing the Development of Th17 Cells and Synthesis of Proinflammatory Cytokines by Such Cells, via Inhibition of NF-κB. PLoS ONE. 2015;10:e0138201 pubmed 出版商
|
Dong B, Shi Z, Wang J, Wu J, Yang Z, Fang K. IL-6 Inhibits the Targeted Modulation of PDCD4 by miR-21 in Prostate Cancer. PLoS ONE. 2015;10:e0134366 pubmed 出版商
|
Yousef S, Heise J, Lajmi N, Bartels K, Kröger N, Luetkens T, et al. Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma. J Transl Med. 2015;13:197 pubmed 出版商
|
Gopinathan G, Milagre C, Pearce O, Reynolds L, Hodivala Dilke K, Leinster D, et al. Interleukin-6 Stimulates Defective Angiogenesis. Cancer Res. 2015;75:3098-107 pubmed 出版商
|
Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg L, et al. Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy. J Hematol Oncol. 2015;8:64 pubmed 出版商
|
Hong S, Choi J, Lee S, Park Y, Park K, Lee J, et al. A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor β Subunit, Glycoprotein 130. J Immunol. 2015;195:237-45 pubmed 出版商
|
Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, et al. Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis. J Exp Med. 2015;212:619-31 pubmed 出版商
|
Kim J, Tillu D, Quinn T, Mejia G, Shy A, Asiedu M, et al. Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. J Neurosci. 2015;35:6307-17 pubmed 出版商
|
Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, et al. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med. 2015;21:530-6 pubmed 出版商
|
Simamura E, Arikawa T, Ikeda T, Shimada H, Shoji H, Masuta H, et al. Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. PLoS ONE. 2015;10:e0123232 pubmed 出版商
|
Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, et al. Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M. Respir Res. 2015;16:14 pubmed 出版商
|
Camargo J, Bhimji A, Kumar D, Kaul R, Pavan R, Schuh A, et al. Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis. PLoS ONE. 2015;10:e0123171 pubmed 出版商
|
Patterson S, Rossi J, Paweletz K, Fitzpatrick V, Begley C, Busse L, et al. Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues. PLoS ONE. 2015;10:e0122149 pubmed 出版商
|
Irvin S, Herold B. Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk. PLoS ONE. 2015;10:e0121135 pubmed 出版商
|
Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed 出版商
|
Canavan J, Scotta C, Vossenkamper A, Goldberg R, Elder M, Shoval I, et al. Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease. Gut. 2016;65:584-94 pubmed 出版商
|
Bhardwaj R, Yester J, Singh S, Biswas D, Surace M, Waters M, et al. RelB/p50 complexes regulate cytokine-induced YKL-40 expression. J Immunol. 2015;194:2862-70 pubmed 出版商
|
Lee J, Graham M, Collins T, Lee J, Hong S, Mcnicol A, et al. Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. Stem Cells. 2015;33:1142-52 pubmed 出版商
|
Fichtner S, Hose D, Engelhardt M, Meißner T, Neuber B, Krasniqi F, et al. Association of antigen-specific T-cell responses with antigen expression and immunoparalysis in multiple myeloma. Clin Cancer Res. 2015;21:1712-21 pubmed 出版商
|
Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, et al. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci. 2015;56:1051-62 pubmed 出版商
|
Goedken E, Argiriadi M, Banach D, Fiamengo B, Foley S, Frank K, et al. Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol. J Biol Chem. 2015;290:4573-89 pubmed 出版商
|
Venkatesha V, Joshi A, Venkataraman M, Sonawane V, Bhatia D, Tannu P, et al. P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer. Mol Cancer. 2014;13:259 pubmed 出版商
|
Lee D, Sung K, Bartlett D, Kwon Y, Lee Y. HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells. Cell Signal. 2015;27:293-305 pubmed 出版商
|
Sobotta M, Liou W, Stöcker S, Talwar D, Oehler M, Ruppert T, et al. Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling. Nat Chem Biol. 2015;11:64-70 pubmed 出版商
|
Lam S, Sung J, Cruz C, Castillo Caro P, Ngo M, Garrido C, et al. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy. Mol Ther. 2015;23:387-95 pubmed 出版商
|
Chinen Y, Kuroda J, Shimura Y, Nagoshi H, Kiyota M, Yamamoto Sugitani M, et al. Phosphoinositide protein kinase PDPK1 is a crucial cell signaling mediator in multiple myeloma. Cancer Res. 2014;74:7418-29 pubmed 出版商
|
Davaine J, Quillard T, Brion R, Lapérine O, Guyomarch B, Merlini T, et al. Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability. PLoS ONE. 2014;9:e107642 pubmed 出版商
|
Kuang D, Xiao X, Zhao Q, Chen M, Li X, Liu R, et al. B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest. 2014;124:4657-67 pubmed 出版商
|
Zhu H, Han C, Lu D, Wu T. miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator. Am J Pathol. 2014;184:2828-39 pubmed 出版商
|
Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, et al. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE. 2014;9:e106673 pubmed 出版商
|
Kwon S, Lee J, Lee S, Jung S, Kim D, Kang S, et al. Cross talk with hematopoietic cells regulates the endothelial progenitor cell differentiation of CD34 positive cells. PLoS ONE. 2014;9:e106310 pubmed 出版商
|
Dighe N, Khoury M, Mattar C, Chong M, Choolani M, Chen J, et al. Long-term reproducible expression in human fetal liver hematopoietic stem cells with a UCOE-based lentiviral vector. PLoS ONE. 2014;9:e104805 pubmed 出版商
|
Bam R, Venkateshaiah S, Khan S, Ling W, Randal S, Li X, et al. Role of Bruton's tyrosine kinase (BTK) in growth and metastasis of INA6 myeloma cells. Blood Cancer J. 2014;4:e234 pubmed 出版商
|
Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K. Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk. J Immunol. 2014;193:2297-305 pubmed 出版商
|
Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, et al. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor ?t (ROR?t) in Th17 cells. J Biol Chem. 2014;289:25546-55 pubmed 出版商
|
Zhang Q, Yang Z, Jia Z, Liu C, Guo C, Lu H, et al. ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex. Mol Cancer. 2014;13:181 pubmed 出版商
|
O TOOLE A, Michielsen A, Nolan B, Tosetto M, Sheahan K, Mulcahy H, et al. Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive. Br J Cancer. 2014;111:927-32 pubmed 出版商
|
Weinkopff T, Mackenzie C, Eversole R, Lammie P. Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediators. PLoS Negl Trop Dis. 2014;8:e2893 pubmed 出版商
|
Melemedjian O, Tillu D, Moy J, Asiedu M, Mandell E, Ghosh S, et al. Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Mol Pain. 2014;10:45 pubmed 出版商
|
Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, et al. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood. 2014;124:1393-403 pubmed 出版商
|
Kastrati I, Canestrari E, Frasor J. PHLDA1 expression is controlled by an estrogen receptor-NF?B-miR-181 regulatory loop and is essential for formation of ER+ mammospheres. Oncogene. 2015;34:2309-16 pubmed 出版商
|
Tanaka A, Zhu Q, Tan H, Horiba H, Ohnuki K, Mori Y, et al. Biological activities and phytochemical profiles of extracts from different parts of bamboo (Phyllostachys pubescens). Molecules. 2014;19:8238-60 pubmed 出版商
|
Bettini M, Blanchfield L, Castellaw A, Zhang Q, Nakayama M, Smeltzer M, et al. TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. J Immunol. 2014;193:571-9 pubmed 出版商
|
Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, et al. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition. Cancer Res. 2014;74:4458-69 pubmed 出版商
|
Linher Melville K, Singh G. The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells. BMC Cancer. 2014;14:415 pubmed 出版商
|
Horwitz M, Chao N, Rizzieri D, Long G, Sullivan K, Gasparetto C, et al. Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment. J Clin Invest. 2014;124:3121-8 pubmed 出版商
|
Volpe E, Pattarini L, Martinez Cingolani C, Meller S, Donnadieu M, Bogiatzi S, et al. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis. J Allergy Clin Immunol. 2014;134:373-81 pubmed 出版商
|
Zhao Y, Xiao X, Frank S, Lin H, Xia Y. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-?, and IL-1?. Am J Physiol Endocrinol Metab. 2014;307:E186-98 pubmed 出版商
|
Kofler D, Marson A, Dominguez Villar M, Xiao S, Kuchroo V, Hafler D. Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. J Clin Invest. 2014;124:2513-22 pubmed 出版商
|
Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, et al. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE. 2014;9:e96695 pubmed 出版商
|
Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, et al. Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. J Cell Sci. 2014;127:2761-70 pubmed 出版商
|
Richter R, Jochheim Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, et al. Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells. Stem Cells Dev. 2014;23:1959-74 pubmed 出版商
|
Zheng Y, Chow S, Boernert K, Basel D, Mikuscheva A, Kim S, et al. Direct crosstalk between cancer and osteoblast lineage cells fuels metastatic growth in bone via auto-amplification of IL-6 and RANKL signaling pathways. J Bone Miner Res. 2014;29:1938-49 pubmed 出版商
|
Shaw S, Bourne T, Meier C, Carrington B, Gelinas R, Henry A, et al. Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling. MAbs. 2014;6:774-82 pubmed 出版商
|
Al Sadi R, Ye D, Boivin M, Guo S, Hashimi M, Ereifej L, et al. Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene. PLoS ONE. 2014;9:e85345 pubmed 出版商
|
Umashankar M, Rak M, Bughio F, Zagallo P, Caviness K, Goodrum F. Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection. J Virol. 2014;88:5987-6002 pubmed 出版商
|
Pei X, Dai Y, Felthousen J, Chen S, Takabatake Y, Zhou L, et al. Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells. PLoS ONE. 2014;9:e89064 pubmed 出版商
|
Di Martino M, Gullà A, Gallo Cantafio M, Altomare E, Amodio N, Leone E, et al. In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells. PLoS ONE. 2014;9:e89659 pubmed 出版商
|
Liu R, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, et al. JAK/STAT3 signaling is required for TGF-?-induced epithelial-mesenchymal transition in lung cancer cells. Int J Oncol. 2014;44:1643-51 pubmed 出版商
|
O Reilly S, Ciechomska M, Cant R, van Laar J. Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-? (TGF-?) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem. 2014;289:9952-60 pubmed 出版商
|
Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, et al. The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation. Eur J Immunol. 2014;44:1330-40 pubmed 出版商
|
Valle Oseguera C, Spencer J. cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells. PLoS ONE. 2014;9:e88708 pubmed 出版商
|
Milwid J, Elman J, Li M, Shen K, Manrai A, Gabow A, et al. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators. Mol Ther. 2014;22:999-1007 pubmed 出版商
|
Jensen B, Frandsen P, Raaby E, Schiøtz P, Skov P, Poulsen L. Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells. J Leukoc Biol. 2014;95:893-901 pubmed 出版商
|
McCutcheon K, Gray J, Chen N, Liu K, Park M, Ellsworth S, et al. Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targets. MAbs. 2014;6:460-73 pubmed 出版商
|
Zhang M, Qian J, Lan Y, Lu Y, Li H, Hong B, et al. Anti-??M monoclonal antibodies kill myeloma cells via cell- and complement-mediated cytotoxicity. Int J Cancer. 2014;135:1132-41 pubmed 出版商
|
Imai F, Kishi H, Nakao K, Nishimura T, Minegishi T. IL-6 up-regulates the expression of rat LH receptors during granulosa cell differentiation. Endocrinology. 2014;155:1436-44 pubmed 出版商
|
Rodin S, Antonsson L, Niaudet C, Simonson O, Salmela E, Hansson E, et al. Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment. Nat Commun. 2014;5:3195 pubmed 出版商
|
Mok J, Mindrinos M, Davis R, Javanmard M. Digital microfluidic assay for protein detection. Proc Natl Acad Sci U S A. 2014;111:2110-5 pubmed 出版商
|
Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S. MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells. Stem Cells. 2014;32:1337-46 pubmed 出版商
|
Gupta S, Hirota M, Waugh S, Murakami I, Suzuki T, Muraguchi M, et al. Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor. J Biol Chem. 2014;289:8706-19 pubmed 出版商
|
Suzuki H, Raska M, Yamada K, Moldoveanu Z, Julian B, Wyatt R, et al. Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes. J Biol Chem. 2014;289:5330-9 pubmed 出版商
|
Mleczko Sanecka K, Roche F, da Silva A, Call D, D Alessio F, Ragab A, et al. Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. Blood. 2014;123:1574-85 pubmed 出版商
|
Thanunchai M, Kanrai P, Wiboon ut S, Puthavathana P, Hongeng S, Thitithanyanont A. Tropism of avian influenza A (H5N1) virus to mesenchymal stem cells and CD34+ hematopoietic stem cells. PLoS ONE. 2013;8:e81805 pubmed 出版商
|
Wong K, Wan T, So C, Chim C. Establishment of a bortezomib-resistant Chinese human multiple myeloma cell line: MMLAL. Cancer Cell Int. 2013;13:122 pubmed 出版商
|
Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, et al. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. J Invest Dermatol. 2014;134:1246-1254 pubmed 出版商
|
Sjeklocha L, Wong P, Belcher J, Vercellotti G, Steer C. ?-Globin sleeping beauty transposon reduces red blood cell sickling in a patient-derived CD34(+)-based in vitro model. PLoS ONE. 2013;8:e80403 pubmed 出版商
|
McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, et al. NF-?B-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma. PLoS ONE. 2013;8:e78728 pubmed 出版商
|
Csaszar E, Wang W, Usenko T, Qiao W, Delaney C, Bernstein I, et al. Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood. 2014;123:650-8 pubmed 出版商
|
Dowty M, Jesson M, Ghosh S, Lee J, Meyer D, Krishnaswami S, et al. Preclinical to clinical translation of tofacitinib, a Janus kinase inhibitor, in rheumatoid arthritis. J Pharmacol Exp Ther. 2014;348:165-73 pubmed 出版商
|
Mele V, Muraro M, Calabrese D, Pfaff D, Amatruda N, Amicarella F, et al. Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-?. Int J Cancer. 2014;134:2583-94 pubmed 出版商
|
Mercier S, Donaghy H, Botting R, Turville S, Harman A, Nasr N, et al. The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes. PLoS Pathog. 2013;9:e1003700 pubmed 出版商
|
Todd J, Simpson P, Estis J, Torres V, Wub A. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. Cytokine. 2013;64:660-5 pubmed 出版商
|
Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, et al. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell. 2013;13:459-70 pubmed 出版商
|
Zheng Y, McFarland B, Drygin D, Yu H, Bellis S, Kim H, et al. Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma. Clin Cancer Res. 2013;19:6484-94 pubmed 出版商
|
Samsonov A, Zenser N, Zhang F, Zhang H, Fetter J, Malkov D. Tagging of genomic STAT3 and STAT1 with fluorescent proteins and insertion of a luciferase reporter in the cyclin D1 gene provides a modified A549 cell line to screen for selective STAT3 inhibitors. PLoS ONE. 2013;8:e68391 pubmed 出版商
|
Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, et al. Histone deacetylase 3 as a novel therapeutic target in multiple myeloma. Leukemia. 2014;28:680-9 pubmed 出版商
|
Yoo H, Seo J, Yoo J. CTR9, a component of PAF complex, controls elongation block at the c-Fos locus via signal-dependent regulation of chromatin-bound NELF dissociation. PLoS ONE. 2013;8:e61055 pubmed 出版商
|
El Zaatari M, Kao J, Tessier A, Bai L, Hayes M, Fontaine C, et al. Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE. 2013;8:e58935 pubmed 出版商
|
Melemedjian O, Tillu D, Asiedu M, Mandell E, Moy J, Blute V, et al. BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Mol Pain. 2013;9:12 pubmed 出版商
|
Malaponte G, Polesel J, Candido S, Sambataro D, Bevelacqua V, Anzaldi M, et al. IL-6-174 G > C and MMP-9-1562 C > T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients. Cytokine. 2013;62:64-9 pubmed 出版商
|
Yu J, Peng Y, Wu L, Xie Z, Deng Y, Hughes T, et al. Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. PLoS ONE. 2013;8:e55934 pubmed 出版商
|
Leone E, Morelli E, Di Martino M, Amodio N, Foresta U, Gullà A, et al. Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth. Clin Cancer Res. 2013;19:2096-106 pubmed 出版商
|
Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, et al. Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients. Clin Cancer Res. 2013;19:1858-72 pubmed 出版商
|
Verjee L, Verhoekx J, Chan J, Krausgruber T, Nicolaidou V, Izadi D, et al. Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target. Proc Natl Acad Sci U S A. 2013;110:E928-37 pubmed 出版商
|
Koeth R, Kalantar Zadeh K, Wang Z, Fu X, Tang W, Hazen S. Protein carbamylation predicts mortality in ESRD. J Am Soc Nephrol. 2013;24:853-61 pubmed 出版商
|
Giannoni F, Hardee C, Wherley J, Gschweng E, Senadheera S, Kaufman M, et al. Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. Mol Ther. 2013;21:1044-54 pubmed 出版商
|
Johnston A, Xing X, Swindell W, Kochkodan J, Riblett M, Nair R, et al. Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis. Hum Mol Genet. 2013;22:1807-15 pubmed 出版商
|
Park J, Lim M, Cho M, Ryu J, Moon Y, Jhun J, et al. p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice. Arthritis Rheum. 2013;65:949-59 pubmed 出版商
|
Gemperle C, Schmid M, Herova M, Marti Jaun J, Wuest S, Loretz C, et al. Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages. PLoS ONE. 2012;7:e50195 pubmed 出版商
|
Kothari H, Rao L, Vankayalapati R, Pendurthi U. Mycobacterium tuberculosis infection and tissue factor expression in macrophages. PLoS ONE. 2012;7:e45700 pubmed 出版商
|
Zelinka C, Scott M, Volkov L, Fischer A. The reactivity, distribution and abundance of Non-astrocytic Inner Retinal Glial (NIRG) cells are regulated by microglia, acute damage, and IGF1. PLoS ONE. 2012;7:e44477 pubmed 出版商
|
Petrovas C, Yamamoto T, Gerner M, Boswell K, Wloka K, Smith E, et al. CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest. 2012;122:3281-94 pubmed 出版商
|
Wilde S, Geiger C, Milosevic S, Mosetter B, Eichenlaub S, Schendel D. Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells: A three phase experimental procedure. Oncoimmunology. 2012;1:129-140 pubmed
|
Graham L, Gupta V, Schäfer G, Reid D, Kimberg M, Dennehy K, et al. The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase. J Biol Chem. 2012;287:25964-74 pubmed 出版商
|
Napoletano C, Zizzari I, Rughetti A, Rahimi H, Irimura T, Clausen H, et al. Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation. Eur J Immunol. 2012;42:936-45 pubmed 出版商
|
Zielinski C, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, et al. Pathogen-induced human TH17 cells produce IFN-? or IL-10 and are regulated by IL-1?. Nature. 2012;484:514-8 pubmed 出版商
|
Hong Y, Moon S, Joo Y, Jeon C, Cho M, Ju J, et al. Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis. J Korean Med Sci. 2011;26:1132-9 pubmed 出版商
|
von Bubnoff D, Scheler M, Wilms H, Fimmers R, Bieber T. Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli. J Immunol. 2011;186:6701-9 pubmed 出版商
|
Liao W, Lin J, Wang L, Li P, Leonard W. Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat Immunol. 2011;12:551-9 pubmed 出版商
|
Steinbicker A, Sachidanandan C, Vonner A, Yusuf R, Deng D, Lai C, et al. Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood. 2011;117:4915-23 pubmed 出版商
|
Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, et al. Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. Clin Exp Immunol. 2011;163:215-24 pubmed 出版商
|
Xu H, Wang X, Pahar B, Moroney Rasmussen T, Alvarez X, Lackner A, et al. Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression. J Immunol. 2010;185:7340-8 pubmed 出版商
|
Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, et al. Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome). Blood. 2011;117:839-47 pubmed 出版商
|
Jones G, Stumhofer J, Foster T, Twohig J, Hertzog P, Topley N, et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011;25:409-19 pubmed 出版商
|
Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot Ayer D, Gabay C. Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice. J Immunol. 2010;185:2516-24 pubmed 出版商
|
Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood. 2010;116:3099-107 pubmed 出版商
|
Trowbridge J, Guezguez B, Moon R, Bhatia M. Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity. Stem Cells. 2010;28:1379-89 pubmed 出版商
|
Morizane S, Yamasaki K, Kabigting F, Gallo R. Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J Invest Dermatol. 2010;130:1297-306 pubmed 出版商
|
Lee W, Kang S, Choi J, Lee S, Shah K, Eynon E, et al. Regulating human Th17 cells via differential expression of IL-1 receptor. Blood. 2010;115:530-40 pubmed 出版商
|
Heo Y, Joo Y, Oh H, Park M, Heo Y, Cho M, et al. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett. 2010;127:150-6 pubmed 出版商
|
Funderburg N, Mayne E, Sieg S, Asaad R, Jiang W, Kalinowska M, et al. Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. Blood. 2010;115:161-7 pubmed 出版商
|
Margulis A, Nocka K, Brennan A, Deng B, Fleming M, Goldman S, et al. Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases. J Immunol. 2009;183:1739-50 pubmed 出版商
|
Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol. 2009;10:857-63 pubmed 出版商
|
Ye L, Chang J, Lin C, Sun X, Yu J, Kan Y. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases. Proc Natl Acad Sci U S A. 2009;106:9826-30 pubmed 出版商
|
Niu K, Huang W, Lin M, Huang K. Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits. Eur J Pharmacol. 2009;606:240-5 pubmed 出版商
|
Aliahmadi E, Gramlich R, Grützkau A, Hitzler M, Krüger M, Baumgrass R, et al. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur J Immunol. 2009;39:1221-30 pubmed 出版商
|
Boniface K, Bak Jensen K, Li Y, Blumenschein W, McGeachy M, McClanahan T, et al. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J Exp Med. 2009;206:535-48 pubmed 出版商
|
Amiable N, Tat S, Lajeunesse D, Duval N, Pelletier J, Martel Pelletier J, et al. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone. 2009;44:1143-50 pubmed 出版商
|
Eid R, Rao D, Zhou J, Lo S, Ranjbaran H, Gallo A, et al. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation. 2009;119:1424-32 pubmed 出版商
|
Yammani R, Long D, Loeser R. Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis Rheum. 2009;60:792-800 pubmed 出版商
|
Mizutani K, Sud S, Pienta K. Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts. J Cell Biochem. 2009;106:563-9 pubmed 出版商
|
Ara T, Song L, Shimada H, Keshelava N, Russell H, Metelitsa L, et al. Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res. 2009;69:329-37 pubmed 出版商
|
Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, et al. IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J Allergy Clin Immunol. 2009;123:59-66.e4 pubmed 出版商
|
Kwan Tat S, Pelletier J, Amiable N, Boileau C, Lajeunesse D, Duval N, et al. Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts. Arthritis Rheum. 2008;58:3820-30 pubmed 出版商
|
Ahmed S, Marotte H, Kwan K, Ruth J, Campbell P, Rabquer B, et al. Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production. Proc Natl Acad Sci U S A. 2008;105:14692-7 pubmed 出版商
|
Kolliputi N, Waxman A. IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation. Am J Respir Cell Mol Biol. 2009;40:314-24 pubmed 出版商
|
Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, et al. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J Immunol. 2008;181:2772-80 pubmed
|
Osei Kumah A, Smith R, Clifton V. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine. 2008;43:187-93 pubmed 出版商
|
Gerber S, Pober J. IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells. J Immunol. 2008;181:1052-62 pubmed
|
Jasny E, Eisenblatter M, Mätz Rensing K, Tenner Racz K, Tenbusch M, Schrod A, et al. IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation. J Immunol. 2008;180:6629-39 pubmed
|
Kato A, Peters A, Suh L, Carter R, Harris K, Chandra R, et al. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2008;121:1385-92, 1392.e1-2 pubmed 出版商
|
Chong D, Boehlke C, Zheng Q, Zhang L, Han Y, Zacks D. Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci. 2008;49:3193-200 pubmed 出版商
|
Gunetti M, Ferrero I, Rustichelli D, Berger M, Gammaitoni L, Timeus F, et al. Refreezing of cord blood hematopoietic stem cells for allogenic transplantation: in vitro and in vivo validation of a clinical phase I/II protocol in European and Italian Good Manufacturing Practice conditions. Exp Hematol. 2008;36:235-43 pubmed 出版商
|
Yang H, Cohen P, Rousseau S. IL-1beta-stimulated activation of ERK1/2 and p38alpha MAPK mediates the transcriptional up-regulation of IL-6, IL-8 and GRO-alpha in HeLa cells. Cell Signal. 2008;20:375-80 pubmed
|
Liotta F, Angeli R, Cosmi L, Filì L, Manuelli C, Frosali F, et al. Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells. 2008;26:279-89 pubmed
|
Neri P, Kumar S, Fulciniti M, Vallet S, Chhetri S, Mukherjee S, et al. Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model. Clin Cancer Res. 2007;13:5903-9 pubmed
|
Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, et al. Ultrasensitive flow-based immunoassays using single-molecule counting. Clin Chem. 2007;53:1990-5 pubmed
|
Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, et al. Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration. J Biol Chem. 2007;282:31643-55 pubmed
|
Zahorchak A, Kean L, Tokita D, Turnquist H, Abe M, Finke J, et al. Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques. Transplantation. 2007;84:196-206 pubmed
|
Luty W, Rodeberg D, Parness J, Vyas Y. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J Immunol. 2007;179:819-29 pubmed
|
Kelley M, Rose A, Song K, Chen Y, Bradley J, Rookhuizen D, et al. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork. Invest Ophthalmol Vis Sci. 2007;48:2634-43 pubmed
|
Wolk K, Witte E, Hoffmann U, Doecke W, Endesfelder S, Asadullah K, et al. IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease. J Immunol. 2007;178:5973-81 pubmed
|
Gross M, Top I, Laux I, Katz J, Curran J, Tindell C, et al. Beta-2-microglobulin is an androgen-regulated secreted protein elevated in serum of patients with advanced prostate cancer. Clin Cancer Res. 2007;13:1979-86 pubmed
|
van Grevenstein W, Hofland L, van Rossen M, van Koetsveld P, Jeekel J, van Eijck C. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers. Dig Dis Sci. 2007;52:2775-83 pubmed
|
Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression. Int J Oncol. 2007;30:977-83 pubmed
|
Brechter A, Lerner U. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression. Arthritis Rheum. 2007;56:910-23 pubmed
|
Ettinger R, Sims G, Robbins R, Withers D, Fischer R, Grammer A, et al. IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J Immunol. 2007;178:2872-82 pubmed
|
Rajesh D, Chinnasamy N, Mitalipov S, Wolf D, Slukvin I, Thomson J, et al. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells. 2007;25:490-9 pubmed
|
Strandberg K, Palmberg L, Larsson K. Effect of formoterol and salmeterol on IL-6 and IL-8 release in airway epithelial cells. Respir Med. 2007;101:1132-9 pubmed
|
Johnson L, Clasper S, Holt A, Lalor P, Baban D, Jackson D. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J Exp Med. 2006;203:2763-77 pubmed
|
Sugaya M, Fang L, Cardones A, Kakinuma T, Jaber S, Blauvelt A, et al. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes. J Immunol. 2006;177:7665-72 pubmed
|
Orfanos S, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, et al. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators. Crit Care Med. 2007;35:199-206 pubmed
|
Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L. Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression. J Endocrinol. 2006;191:65-81 pubmed
|
Ammit A, Moir L, Oliver B, Hughes J, Alkhouri H, Ge Q, et al. Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2007;292:L199-206 pubmed
|
Acevedo F, Palmberg L, Larsson K. Exposure to organic dust causes activation of human plasma complement factors C3 and B and the synthesis of factor C3 by lung epithelial cells in vitro. Inflammation. 2005;29:39-45 pubmed
|
Pavon L, Sandoval López G, Eugenia Hernández M, Loría F, Estrada I, Perez M, et al. Th2 cytokine response in Major Depressive Disorder patients before treatment. J Neuroimmunol. 2006;172:156-65 pubmed
|
Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, et al. Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells. Cell Death Differ. 2006;13:1686-96 pubmed
|
Mortara L, Ploquin M, Faye A, Scott Algara D, Vaslin B, BUTOR C, et al. Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes. J Immunol Methods. 2006;308:138-55 pubmed
|
Von Strandmann E, Hansen H, Reiners K, Schnell R, Borchmann P, Merkert S, et al. A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo. Blood. 2006;107:1955-62 pubmed
|
Hsieh F, Sharma P, Gibbons A, Goggans T, Erzurum S, Haque S. Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells. Proc Natl Acad Sci U S A. 2005;102:14380-5 pubmed
|
Hanley M, Napolitano L, McCune J. Growth hormone-induced stimulation of multilineage human hematopoiesis. Stem Cells. 2005;23:1170-9 pubmed
|
Holst R, Mattsby Baltzer I, Wennerholm U, Hagberg H, Jacobsson B. Interleukin-6 and interleukin-8 in cervical fluid in a population of Swedish women in preterm labor: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation, and preterm delivery. Acta Obstet Gynecol Scand. 2005;84:551-7 pubmed
|
Mandelin J, Li T, Hukkanen M, Liljeström M, Salo J, Santavirta S, et al. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K. J Rheumatol. 2005;32:713-20 pubmed
|
Mozaffarian D, Rimm E, King I, Lawler R, McDonald G, Levy W. trans fatty acids and systemic inflammation in heart failure. Am J Clin Nutr. 2004;80:1521-5 pubmed
|
Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, et al. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc Natl Acad Sci U S A. 2004;101:16606-11 pubmed
|
Nagineni C, Kutty V, Detrick B, Hooks J. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J Cell Physiol. 2005;203:35-43 pubmed
|
Kao C, Chen Y, Thai P, Wachi S, Huang F, Kim C, et al. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol. 2004;173:3482-91 pubmed
|
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R. IL-22 increases the innate immunity of tissues. Immunity. 2004;21:241-54 pubmed
|
Phillips T. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis. 2004;25:1652-9 pubmed
|
Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, et al. Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus. J Virol. 2004;78:6151-61 pubmed
|
Bas S, Gauthier B, Spenato U, Stingelin S, Gabay C. CD14 is an acute-phase protein. J Immunol. 2004;172:4470-9 pubmed
|
Copeland S, Siddiqui J, Remick D. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J Immunol Methods. 2004;284:99-106 pubmed
|
McLoughlin R, Witowski J, Robson R, Wilkinson T, Hurst S, Williams A, et al. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J Clin Invest. 2003;112:598-607 pubmed
|
Hurst S, McLoughlin R, Monslow J, Owens S, Morgan L, Fuller G, et al. Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J Immunol. 2002;169:5244-51 pubmed
|
Erices A, Conget P, Rojas C, Minguell J. Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells. Exp Cell Res. 2002;280:24-32 pubmed
|
Cork B, Tuckerman E, Li T, Laird S. Expression of interleukin (IL)-11 receptor by the human endometrium in vivo and effects of IL-11, IL-6 and LIF on the production of MMP and cytokines by human endometrial cells in vitro. Mol Hum Reprod. 2002;8:841-8 pubmed
|
Manz M, Miyamoto T, Akashi K, Weissman I. Prospective isolation of human clonogenic common myeloid progenitors. Proc Natl Acad Sci U S A. 2002;99:11872-7 pubmed
|
Shih C, Hu M, Hu J, Weng Y, Yazaki P, Medeiros J, et al. A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood. 2000;95:1957-66 pubmed
|
Gomez Navarro J, Contreras J, Arafat W, Jiang X, Krisky D, Oligino T, et al. Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model. Gene Ther. 2000;7:43-52 pubmed
|
Akagi Y, Liu W, Zebrowski B, Xie K, Ellis L. Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I. Cancer Res. 1998;58:4008-14 pubmed
|
Barcena A, Park S, Banapour B, Muench M, Mechetner E. Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood. 1996;88:2013-25 pubmed
|