产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类神经纤毛蛋白2 Fc嵌合体蛋白, CF
目录 :
2215-N2-025
规格 :
25微克
价格 :
423美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 9
参考文献
Fornara C, Schultz E, Lilleri D, Baldanti F, RYCKMAN B, Gerna G. Fibroblast, Epithelial and Endothelial Cell-Derived Human Cytomegalovirus Strains Display Distinct Neutralizing Antibody Responses and Varying Levels of gH/gL Complexes. Int J Mol Sci. 2023;24: pubmed 出版商
Braun B, Laib Sampaio K, Kuderna A, Widmann M, Sinzger C. Viral and Cellular Factors Contributing to the Hematogenous Dissemination of Human Cytomegalovirus via Polymorphonuclear Leukocytes. Viruses. 2022;14: pubmed 出版商
Dutta S, Polavaram N, Islam R, Bhattacharya S, Bodas S, Mayr T, et al. Neuropilin-2 regulates androgen-receptor transcriptional activity in advanced prostate cancer. Oncogene. 2022;41:3747-3760 pubmed 出版商
Martinez Martin N, Marcandalli J, Huang C, Arthur C, Perotti M, Foglierini M, et al. An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor. Cell. 2018;174:1158-1171.e19 pubmed 出版商
Harris N, Davydova N, Roufail S, Paquet Fifield S, Paavonen K, Karnezis T, et al. The propeptides of VEGF-D determine heparin binding, receptor heterodimerization, and effects on tumor biology. J Biol Chem. 2013;288:8176-86 pubmed 出版商
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed 出版商
Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood. 2010;116:3099-107 pubmed 出版商
Fassold A, Falk W, Anders S, Hirsch T, Mirsky V, Straub R. Soluble neuropilin-2, a nerve repellent receptor, is increased in rheumatoid arthritis synovium and aggravates sympathetic fiber repulsion and arthritis. Arthritis Rheum. 2009;60:2892-901 pubmed 出版商
Jaalouk D, Ozawa M, Sun J, Lahdenranta J, Schlingemann R, Pasqualini R, et al. The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1. Cancer Res. 2007;67:9623-9 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
2215-N2
SKU号 :
2215-N2-025
产品名称 :
重组人类神经纤毛蛋白2 Fc嵌合体蛋白, CF
描述 :
The Recombinant Human Neuropilin-2 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Neuropilin-2 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
靶标 :
神经纤毛蛋白2
类别 :
蛋白和酶
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
140 kDa, reducing conditions
理论上的分子量 :
120.5 kDa (monomer)
基因符号 :
NRP2
功能细节 :
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human (rh) Neuropilin-2 Fc Chimera can bind rhVEGF165 with an apparent KD 5 nM.
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q7LBX6
应用 :
结合活性
来源 :
NS0-derived Recombinant Human Neuropilin-2 Fc Chimera Protein
美元 :
423美元
别名 :
MGC126574, neuropilin 2, neuropilin-2, Neuropilin2, neuropilin-2a(22), neuropilin-2b(0), NP2, NPN 2, NPN2, PRO2714, receptor for VEGF165 and semaphorins class3, Vascular endothelial cell growth factor 165 receptor 2, vascular endothelial growth factor-165 receptor 2, VEGF1265R2, VEGF165R2neuropilin-2a(17)
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.