This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类TGF乙1蛋白
目录 :
240-B
规格 :
2 ug (also 10 ug)
价格 :
259美元
文章摘录数: 675
参考文献
Cook D, Vanderhyden B. Context specificity of the EMT transcriptional response. Nat Commun. 2020;11:2142 pubmed 出版商
Nhu Q, Hsieh L, Dohil L, Dohil R, Newbury R, Kurten R, et al. Antifibrotic Effects of the Thiazolidinediones in Eosinophilic Esophagitis Pathologic Remodeling: A Preclinical Evaluation. Clin Transl Gastroenterol. 2020;11:e00164 pubmed 出版商
Kang I, Jang J, Kim C. Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation. Sci Rep. 2020;10:7024 pubmed 出版商
Torres A, Muñoz K, Nahuelpán Y, R Saez A, Mendoza P, Jara C, et al. Intraglomerular Monocyte/Macrophage Infiltration and Macrophage-Myofibroblast Transition during Diabetic Nephropathy Is Regulated by the A2B Adenosine Receptor. Cells. 2020;9: pubmed 出版商
Beauford S, Kumari A, Garnett Benson C. Ionizing radiation modulates the phenotype and function of human CD4+ induced regulatory T cells. BMC Immunol. 2020;21:18 pubmed 出版商
Wang Y, Suk F, Liu C, Chen T, Twu Y, Hsu M, et al. Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-κB Signaling Pathway in Hepatic Stellate Cells. Front Pharmacol. 2020;11:388 pubmed 出版商
Liu M, Xiao Y, Tang W, Li J, Hong L, Dai W, et al. HOXD9 promote epithelial-mesenchymal transition and metastasis in colorectal carcinoma. Cancer Med. 2020;9:3932-3943 pubmed 出版商
Senavirathna L, Huang C, Pushparaj S, Xu D, Liu L. Hypoxia and transforming growth factor β1 regulation of long non-coding RNA transcriptomes in human pulmonary fibroblasts. Physiol Rep. 2020;8:e14343 pubmed 出版商
Li X, Fang P, Sun Y, Shao Y, Yang W, Jiang X, et al. Anti-inflammatory cytokines IL-35 and IL-10 block atherogenic lysophosphatidylcholine-induced, mitochondrial ROS-mediated innate immune activation, but spare innate immune memory signature in endothelial cells. Redox Biol. 2020;28:101373 pubmed 出版商
Kramer M, Markart P, Drakopanagiotakis F, Mamazhakypov A, Schaefer L, Didiasova M, et al. Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system. Cell Signal. 2020;65:109432 pubmed 出版商
Huang Y, Wu C, Xie H, Li Z, Silini A, Parolini O, et al. Strontium Promotes the Proliferation and Osteogenic Differentiation of Human Placental Decidual Basalis- and Bone Marrow-Derived MSCs in a Dose-Dependent Manner. Stem Cells Int. 2019;2019:4242178 pubmed 出版商
Andersen L, Gülich A, Alteneder M, Preglej T, Orola M, Dhele N, et al. The Transcription Factor MAZR/PATZ1 Regulates the Development of FOXP3+ Regulatory T Cells. Cell Rep. 2019;29:4447-4459.e6 pubmed 出版商
Li B, Yan C, Wu J, Stephane K, Dong X, Zhang Y, et al. Clonorchis sinensis ESPs enhance the activation of hepatic stellate cells by a cross-talk of TLR4 and TGF-β/Smads Signaling pathway. Acta Trop. 2019;:105307 pubmed 出版商
Tochimoto M, Oguri Y, Hashimura M, Konno R, Matsumoto T, Yokoi A, et al. S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma. Lab Invest. 2019;: pubmed 出版商
Huang J, Chang S, Lu Y, Wang J, Si Y, Zhang L, et al. Enhanced osteopontin splicing regulated by RUNX2 is HDAC-dependent and induces invasive phenotypes in NSCLC cells. Cancer Cell Int. 2019;19:306 pubmed 出版商
Stylianou P, Clark K, Gooptu B, Smallwood D, Brightling C, Amrani Y, et al. Tensin1 expression and function in chronic obstructive pulmonary disease. Sci Rep. 2019;9:18942 pubmed 出版商
Foxall E, Staszowska A, Hirvonen L, Georgouli M, Ciccioli M, Rimmer A, et al. PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells. Cell Rep. 2019;29:3385-3393.e6 pubmed 出版商
Scott R, Arostegui M, Schweitzer R, Rossi F, Underhill T. Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration. Cell Stem Cell. 2019;25:797-813.e9 pubmed 出版商
Choi J, Kim S, Lee G, Jin S, Lee H, Chung Y, et al. Platyconic Acid A, Platycodi Radix-Derived Saponin, Suppresses TGF-1-induced Activation of Hepatic Stellate Cells via Blocking SMAD and Activating the PPAR Signaling Pathway. Cells. 2019;8: pubmed 出版商
Ni B, Tzao C, Huang J. Plug-and-Play In Vitro Metastasis System toward Recapitulating the Metastatic Cascade. Sci Rep. 2019;9:18110 pubmed 出版商
Horne A, Ahmad S, Carter R, Simitsidellis I, Greaves E, Hogg C, et al. Repurposing dichloroacetate for the treatment of women with endometriosis. Proc Natl Acad Sci U S A. 2019;116:25389-25391 pubmed 出版商
Uyama N, Tsutsui H, Wu S, Yasuda K, Hatano E, Qin X, et al. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation. Sci Rep. 2019;9:17558 pubmed 出版商
Basma H, Johanson A, Dhar K, Anderson D, Qiu F, Rennard S, et al. TGF-β induces a heart failure phenotype via fibroblasts exosome signaling. Heliyon. 2019;5:e02633 pubmed 出版商
Pham D, Moseley C, Gao M, Savic D, Winstead C, Sun M, et al. Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf. Cell Rep. 2019;29:1203-1220.e7 pubmed 出版商
Welk V, Meul T, Lukas C, Kammerl I, Mulay S, Schamberger A, et al. Proteasome activator PA200 regulates myofibroblast differentiation. Sci Rep. 2019;9:15224 pubmed 出版商
Yao F, Wang X, Cui Z, Lan H, Ai X, Song Q, et al. ETS2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting JUNB transcription. Lab Invest. 2019;: pubmed 出版商
Bhatia D, Chung K, Nakahira K, Patiño E, Rice M, Torres L, et al. Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis. JCI Insight. 2019;4: pubmed 出版商
Li K, Yang L, Li J, Guan C, Zhang S, Lao X, et al. TGFβ induces stemness through non-canonical AKT-FOXO3a axis in oral squamous cell carcinoma. EBioMedicine. 2019;48:70-80 pubmed 出版商
Sachdeva R, Wu M, Johnson K, Kim H, Celebre A, Shahzad U, et al. BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma. Sci Rep. 2019;9:14569 pubmed 出版商
Yoo W, Lee J, Noh K, Lee S, Jung D, Kabir M, et al. Progranulin attenuates liver fibrosis by downregulating the inflammatory response. Cell Death Dis. 2019;10:758 pubmed 出版商
Acheva A, Haghdoost S, Sollazzo A, Launonen V, Kämäräinen M. Presence of Stromal Cells Enhances Epithelial-to-Mesenchymal Transition (EMT) Induction in Lung Bronchial Epithelium after Protracted Exposure to Oxidative Stress of Gamma Radiation. Oxid Med Cell Longev. 2019;2019:4120379 pubmed 出版商
Kamitani T, Murota H, Arase N, Wataya Kaneda M, Sato Nishiuchi R, Sekiguchi K, et al. Expression of polydom in dermal neurofibroma and surrounding dermis in von Recklinghausen's disease. J Dermatol Sci. 2019;96:73-80 pubmed 出版商
Garo L, Ajay A, Fujiwara M, Beynon V, Kuhn C, Gabriely G, et al. Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity. Cell Rep. 2019;28:3353-3366.e5 pubmed 出版商
Berning L, Scharf L, Aplak E, Stucki D, von Montfort C, Reichert A, et al. In vitro selective cytotoxicity of the dietary chalcone cardamonin (CD) on melanoma compared to healthy cells is mediated by apoptosis. PLoS ONE. 2019;14:e0222267 pubmed 出版商
Choi Y, Koo J, Kim H, Seo J, Lee E, Kim W, et al. Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic activation in human intestinal myofibroblasts via inhibition of myocardin-related transcription factor A. Stem Cell Res Ther. 2019;10:291 pubmed 出版商
Sreekumar R, Emaduddin M, Al Saihati H, Moutasim K, Chan J, Spampinato M, et al. Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC. Cell Death Dis. 2019;10:703 pubmed 出版商
Holvoet S, Perrot M, de Groot N, Prioult G, Mikogami T, Verhasselt V, et al. Oral Tolerance Induction to Newly Introduced Allergen is Favored by a Transforming Growth Factor-β-Enriched Formula. Nutrients. 2019;11: pubmed 出版商
Hammond C, Roztocil E, Phipps R, Feldon S, Woeller C. Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor. PLoS ONE. 2019;14:e0222779 pubmed 出版商
Du J, Yan L, Torres R, Gong X, Bian H, Marugán C, et al. Aurora A-Selective Inhibitor LY3295668 Leads to Dominant Mitotic Arrest, Apoptosis in Cancer Cells, and Shows Potent Preclinical Antitumor Efficacy. Mol Cancer Ther. 2019;18:2207-2219 pubmed 出版商
Zhou T, Kyritsi K, Wu N, Francis H, Yang Z, Chen L, et al. Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2-/- mouse model of primary sclerosing cholangitis (PSC). EBioMedicine. 2019;48:130-142 pubmed 出版商
Bogdanova M, Zabirnyk A, Malashicheva A, Enayati K, Karlsen T, Kaljusto M, et al. Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties. Sci Rep. 2019;9:12934 pubmed 出版商
Luong T, Estepa M, Boehme B, Pieske B, Lang F, Eckardt K, et al. Inhibition of vascular smooth muscle cell calcification by vasorin through interference with TGFβ1 signaling. Cell Signal. 2019;64:109414 pubmed 出版商
Lv M, Li Z, Liu J, Lin F, Zhang Q, Li Z, et al. MicroRNA‑155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo. Mol Med Rep. 2019;20:3617-3624 pubmed 出版商
Kaushansky N, Bakos E, Becker Herman S, Shachar I, Ben Nun A. Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms. J Immunol. 2019;203:1857-1866 pubmed 出版商
Kaul R, Risinger A, Mooberry S. Eribulin rapidly inhibits TGF-β-induced Snail expression and can induce Slug expression in a Smad4-dependent manner. Br J Cancer. 2019;121:611-621 pubmed 出版商
Krüger K, Schmid S, Paulsen F, Ignatius A, Klinger P, Hotfiel T, et al. Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair. Int J Mol Sci. 2019;20: pubmed 出版商
Lee Y, Kim D, Jeong S, Hwang Y. Effect of exposure to Asian sand dust-Particulate matter on liver Tenascin-C expression in human cancer cell and mouse hepatic tissue. J Toxicol Sci. 2019;44:633-641 pubmed 出版商
Habiel D, Hohmann M, Espíndola M, Coelho A, Jones I, Jones H, et al. DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis. BMC Pulm Med. 2019;19:165 pubmed 出版商
Kim Y, Kim K, Lee S, Jo J, Park J, Park M, et al. ST2 blockade mitigates peritoneal fibrosis induced by TGF-β and high glucose. J Cell Mol Med. 2019;23:6872-6884 pubmed 出版商
Messerschmidt L, Fischer S, Wiedemann P, Bringmann A, Hollborn M. Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation. Mol Vis. 2019;25:329-344 pubmed
Argemi J, Latasa M, Atkinson S, Blokhin I, Massey V, Gue J, et al. Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Nat Commun. 2019;10:3126 pubmed 出版商
Aoki M, Aoki H, Mukhopadhyay P, Tsuge T, Yamamoto H, Matsumoto N, et al. Sphingosine-1-Phosphate Facilitates Skin Wound Healing by Increasing Angiogenesis and Inflammatory Cell Recruitment with Less Scar Formation. Int J Mol Sci. 2019;20: pubmed 出版商
Saraswati S, Marrow S, Watch L, Young P. Identification of a pro-angiogenic functional role for FSP1-positive fibroblast subtype in wound healing. Nat Commun. 2019;10:3027 pubmed 出版商
Woolston A, Khan K, Spain G, Barber L, Griffiths B, Gonzalez Exposito R, et al. Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer. Cancer Cell. 2019;36:35-50.e9 pubmed 出版商
Pedroza M, To S, Smith J, Agarwal S. Cadherin-11 contributes to liver fibrosis induced by carbon tetrachloride. PLoS ONE. 2019;14:e0218971 pubmed 出版商
Duan J, Li B, Bhakta M, Xie S, Zhou P, Munshi N, et al. Rational Reprogramming of Cellular States by Combinatorial Perturbation. Cell Rep. 2019;27:3486-3499.e6 pubmed 出版商
Stock C, Michaeloudes C, Leoni P, Durham A, Mumby S, Wells A, et al. Bromodomain and Extraterminal (BET) Protein Inhibition Restores Redox Balance and Inhibits Myofibroblast Activation. Biomed Res Int. 2019;2019:1484736 pubmed 出版商
Sakata J, Hirosue A, Yoshida R, Kawahara K, Matsuoka Y, Yamamoto T, et al. HMGA2 Contributes to Distant Metastasis and Poor Prognosis by Promoting Angiogenesis in Oral Squamous Cell Carcinoma. Int J Mol Sci. 2019;20: pubmed 出版商
van Dalen R, De La Cruz Diaz J, Rumpret M, Fuchsberger F, van Teijlingen N, Hanske J, et al. Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses. MBio. 2019;10: pubmed 出版商
Myers D, Norlin E, Vercoulen Y, Roose J. Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells. Cell Rep. 2019;27:1858-1874.e6 pubmed 出版商
Granados Aparici S, Hardy K, Franks S, Sharum I, Waite S, Fenwick M. SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles. Sci Rep. 2019;9:6513 pubmed 出版商
Lien H, Lee Y, Juang Y, Lu Y. Fibrillin-1, a novel TGF-beta-induced factor, is preferentially expressed in metaplastic carcinoma with spindle sarcomatous metaplasia. Pathology. 2019;51:375-383 pubmed 出版商
Higuchi T, Takagi K, Tochimoto A, Ichimura Y, Norose T, Katsumata Y, et al. Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment. Arthritis Res Ther. 2019;21:103 pubmed 出版商
Hadjicharalambous M, Roux B, Csomor E, Feghali Bostwick C, Murray L, Clarke D, et al. Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis. Sci Rep. 2019;9:6020 pubmed 出版商
Peng F, Li H, Li S, Wang Y, Liu W, Gong W, et al. Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway. Lab Invest. 2019;: pubmed 出版商
Diao P, Ge H, Song Y, Wu Y, Li J, Li Z, et al. Overexpression of ZEB2-AS1 promotes epithelial-to-mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma. J Cell Mol Med. 2019;23:4269-4280 pubmed 出版商
Chen D, Cao G, Chen H, Argyopoulos C, Yu H, Su W, et al. Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan. Nat Commun. 2019;10:1476 pubmed 出版商
Wang K, Fang S, Liu Q, Gao J, Wang X, Zhu H, et al. TGF-β1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM. EBioMedicine. 2019;42:458-469 pubmed 出版商
Fleskens V, Minutti C, Wu X, Wei P, Pals C, McCrae J, et al. Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells. Cell Rep. 2019;26:3600-3612.e6 pubmed 出版商
Gramlich R, Aliahmadi E, Peiser M. In Vitro Induction of T Helper 17 Cells by Synergistic Activation of Human Monocyte-Derived Langerhans Cell-Like Cells with Bacterial Agonists. Int J Mol Sci. 2019;20: pubmed 出版商
Hochdörfer T, Winkler C, Pardali K, Mjösberg J. Expression of c-Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells. Eur J Immunol. 2019;49:884-893 pubmed 出版商
Park J, Oh Y, Park Y, Park O, Yang H, Slania S, et al. Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma. Nat Commun. 2019;10:1128 pubmed 出版商
Kim Y, Ahn Y, Jung J, Lee Y, Lee J, Kang J. Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis. Cell Mol Immunol. 2019;: pubmed 出版商
Gao R, Zhang N, Yang J, Zhu Y, Zhang Z, Wang J, et al. Long non-coding RNA ZEB1-AS1 regulates miR-200b/FSCN1 signaling and enhances migration and invasion induced by TGF-β1 in bladder cancer cells. J Exp Clin Cancer Res. 2019;38:111 pubmed 出版商
Liu B, Yu Z, Chen A, Chi J, Ge J, Yu Y, et al. Estrogen receptor-α-miR-1271-SNAI2 feedback loop regulates transforming growth factor-β-induced breast cancer progression. J Exp Clin Cancer Res. 2019;38:109 pubmed 出版商
Kim S, Nikoloudaki G, Michelsons S, Creber K, Hamilton D. Fibronectin synthesis, but not α-smooth muscle expression, is regulated by periostin in gingival healing through FAK/JNK signaling. Sci Rep. 2019;9:2708 pubmed 出版商
Luo Y, Xue Y, Wang J, Dang J, Fang Q, Huang G, et al. Negligible Effect of Sodium Chloride on the Development and Function of TGF-β-Induced CD4+ Foxp3+ Regulatory T Cells. Cell Rep. 2019;26:1869-1879.e3 pubmed 出版商
Wang B, Xu X, Yang Z, Zhang L, Liu Y, Ma A, et al. POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1. EBioMedicine. 2019;41:320-332 pubmed 出版商
Derada Troletti C, Fontijn R, Gowing E, Charabati M, Van het Hof B, Didouh I, et al. Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology. Cell Death Dis. 2019;10:45 pubmed 出版商
Mannaerts I, Thoen L, Eysackers N, Cubero F, Batista Leite S, Coldham I, et al. Unfolded protein response is an early, non-critical event during hepatic stellate cell activation. Cell Death Dis. 2019;10:98 pubmed 出版商
Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, et al. Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation. Nat Commun. 2019;10:549 pubmed 出版商
Pucella J, Cols M, Yen W, Xu S, Chaudhuri J. The B Cell Activation-Induced miR-183 Cluster Plays a Minimal Role in Canonical Primary Humoral Responses. J Immunol. 2019;202:1383-1396 pubmed 出版商
Kijewska M, Viski C, Turrell F, Fitzpatrick A, van Weverwijk A, Gao Q, et al. Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain. Breast Cancer Res. 2019;21:4 pubmed 出版商
Dutta R, Chinnapaiyan S, Rasmussen L, Raju S, Unwalla H. A Neutralizing Aptamer to TGFBR2 and miR-145 Antagonism Rescue Cigarette Smoke- and TGF-β-Mediated CFTR Expression. Mol Ther. 2019;27:442-455 pubmed 出版商
Zheng W, Chen C, Chen S, Fan C, Ruan H. Integrated analysis of long non-coding RNAs and mRNAs associated with peritendinous fibrosis. J Adv Res. 2019;15:49-58 pubmed 出版商
Zhang J, Dunk C, Shynlova O, Caniggia I, Lye S. TGFb1 suppresses the activation of distinct dNK subpopulations in preeclampsia. EBioMedicine. 2019;39:531-539 pubmed 出版商
Martin Mateos R, de Assuncao T, Arab J, Jalan Sakrikar N, Yaqoob U, Greuter T, et al. Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. Cell Mol Gastroenterol Hepatol. 2019;7:197-209 pubmed 出版商
Weng C, Ding P, Liu Y, Hawse J, Subramaniam M, Wu C, et al. Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis. Oncogene. 2019;38:2005-2019 pubmed 出版商
Kunihiro A, Brickey J, Frye J, Luis P, Schneider C, Funk J. Curcumin, but not curcumin-glucuronide, inhibits Smad signaling in TGFβ-dependent bone metastatic breast cancer cells and is enriched in bone compared to other tissues. J Nutr Biochem. 2019;63:150-156 pubmed 出版商
Yamashita T, Asano Y, Saigusa R, Taniguchi T, Nakamura K, Miura S, et al. Increased expression of aquaporin-1 in dermal fibroblasts and dermal microvascular endothelial cells possibly contributes to skin fibrosis and edema in patients with systemic sclerosis. J Dermatol Sci. 2019;93:24-32 pubmed 出版商
Nepon Sixt B, Alexandrow M. TGFβ1 Cell Cycle Arrest Is Mediated by Inhibition of MCM Assembly in Rb-Deficient Conditions. Mol Cancer Res. 2019;17:277-288 pubmed 出版商
Zhang X, Liu L, Deng X, Li D, Cai H, Ma Y, et al. MicroRNA 483-3p targets Pard3 to potentiate TGF-β1-induced cell migration, invasion, and epithelial-mesenchymal transition in anaplastic thyroid cancer cells. Oncogene. 2019;38:699-715 pubmed 出版商
Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed 出版商
Kaylan K, Berg I, Biehl M, Brougham Cook A, Jain I, Jamil S, et al. Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling. elife. 2018;7: pubmed 出版商
Wang J, Liu G, Liu M, Xiang L, Xiao Y, Zhu H, et al. The FOXK1-CCDC43 Axis Promotes the Invasion and Metastasis of Colorectal Cancer Cells. Cell Physiol Biochem. 2018;51:2547-2563 pubmed 出版商
Huang T, Huang X, Shi B, Wang F, Feng W, Yao M. Regulators of Salmonella-host interaction identified by peripheral blood transcriptome profiling: roles of TGFB1 and TRP53 in intracellular Salmonella replication in pigs. Vet Res. 2018;49:121 pubmed 出版商
Liu Y, Lightfoot Y, Seto N, Carmona Rivera C, Moore E, Goel R, et al. Peptidylarginine deiminases 2 and 4 modulate innate and adaptive immune responses in TLR-7-dependent lupus. JCI Insight. 2018;3: pubmed 出版商
Das F, Ghosh Choudhury N, Lee D, Gorin Y, Kasinath B, Choudhury G. Akt2 causes TGFβ-induced deptor downregulation facilitating mTOR to drive podocyte hypertrophy and matrix protein expression. PLoS ONE. 2018;13:e0207285 pubmed 出版商
Park J, Kim M, Song N, Kim J, Seo D, Lee J, et al. A Reciprocal Role of the Smad4-Taz Axis in Osteogenesis and Adipogenesis of Mesenchymal Stem Cells. Stem Cells. 2018;: pubmed 出版商
Kim K, Lee S, Lee H, Shin D, Min D, Kim M, et al. A standardized herbal extract PM014 ameliorates pulmonary fibrosis by suppressing the TGF-β1 pathway. Sci Rep. 2018;8:16860 pubmed 出版商
Chen W, Nyuydzefe M, Weiss J, Zhang J, Waksal S, Zanin Zhorov A. ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells. Sci Rep. 2018;8:16636 pubmed 出版商
Park J, Lee J, Yoon B, Jun E, Lee G, Kim I, et al. Additive effect of bFGF and selenium on expansion and paracrine action of human amniotic fluid-derived mesenchymal stem cells. Stem Cell Res Ther. 2018;9:293 pubmed 出版商
Tang Y, Huang Y, Li J, Qin S, Xu Y, An T, et al. Alterations in exosomal miRNA profile upon epithelial-mesenchymal transition in human lung cancer cell lines. BMC Genomics. 2018;19:802 pubmed 出版商
Zivotić M, Tampe B, Muller G, Müller C, Lipkovski A, Xu X, et al. Modulation of NCAM/FGFR1 signaling suppresses EMT program in human proximal tubular epithelial cells. PLoS ONE. 2018;13:e0206786 pubmed 出版商
Fang F, Xia N, Angulo B, Carey J, Cady Z, Durruthy Durruthy J, et al. A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells. Nat Commun. 2018;9:4384 pubmed 出版商
Inoue M, Okamoto K, Terashima A, Nitta T, Muro R, Negishi Koga T, et al. Arginine methylation controls the strength of γc-family cytokine signaling in T cell maintenance. Nat Immunol. 2018;19:1265-1276 pubmed 出版商
Guo L, Hou Y, Song L, Zhu S, Lin F, Bai Y. D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion. Stem Cells Int. 2018;2018:7168231 pubmed 出版商
Saxena M, Kalathur R, Neutzner M, Christofori G. PyMT-1099, a versatile murine cell model for EMT in breast cancer. Sci Rep. 2018;8:12123 pubmed 出版商
Marsh R, Pfisterer K, Bennett P, Hirvonen L, Gautel M, Jones G, et al. Artifact-free high-density localization microscopy analysis. Nat Methods. 2018;15:689-692 pubmed 出版商
Martinez Martin N, Marcandalli J, Huang C, Arthur C, Perotti M, Foglierini M, et al. An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor. Cell. 2018;174:1158-1171.e19 pubmed 出版商
Dvornikov D, Schneider M, Ohse S, Szczygieł M, Titkova I, Rosenblatt M, et al. Expression ratio of the TGF?-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response. Sci Rep. 2018;8:9517 pubmed 出版商
Conith M, Hu Y, Conith A, Maginnis M, Webb J, Albertson R. Genetic and developmental origins of a unique foraging adaptation in a Lake Malawi cichlid genus. Proc Natl Acad Sci U S A. 2018;115:7063-7068 pubmed 出版商
Bach F, Tellegen A, Beukers M, Miranda Bedate A, Teunissen M, de Jong W, et al. Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside. Oncotarget. 2018;9:26507-26526 pubmed 出版商
Liao Y, Yu C, Hsieh P, Chang Y. miR-200b ameliorates myofibroblast transdifferentiation in precancerous oral submucous fibrosis through targeting ZEB2. J Cell Mol Med. 2018;22:4130-4138 pubmed 出版商
Kunita A, Morita S, Irisa T, Goto A, Niki T, Takai D, et al. MicroRNA-21 in cancer-associated fibroblasts supports lung adenocarcinoma progression. Sci Rep. 2018;8:8838 pubmed 出版商
Qin Z, Fisher G, Voorhees J, Quan T. Actin cytoskeleton assembly regulates collagen production via TGF-β type II receptor in human skin fibroblasts. J Cell Mol Med. 2018;22:4085-4096 pubmed 出版商
Ghodrati F, Mehrabian M, Williams D, Halgas O, Bourkas M, Watts J, et al. The prion protein is embedded in a molecular environment that modulates transforming growth factor ? and integrin signaling. Sci Rep. 2018;8:8654 pubmed 出版商
Al Shareef Z, Kardooni H, Murillo Garzón V, Domenici G, Stylianakis E, Steel J, et al. Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1. Oncogene. 2018;37:5305-5324 pubmed 出版商
Tiwary S, Morales J, Kwiatkowski S, Lang F, Rao G, McCarty J. Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a. Sci Rep. 2018;8:8267 pubmed 出版商
Feng X, Li Z, Wei J, Feng Z, Wu W, Zhao Y. Injectable cartilaginous template transformed BMSCs into vascularized bone. Sci Rep. 2018;8:8244 pubmed 出版商
Hung C, Wilson C, Chow Y, Schnapp L. Role of integrin alpha8 in murine model of lung fibrosis. PLoS ONE. 2018;13:e0197937 pubmed 出版商
Cummins C, Wang X, Nunez Lopez O, Graham G, Tie H, Zhou J, et al. Luteolin-Mediated Inhibition of Hepatic Stellate Cell Activation via Suppression of the STAT3 Pathway. Int J Mol Sci. 2018;19: pubmed 出版商
Chung Y, Huang Y, Chu T, Chen C, Lin P, Huang S, et al. BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling. Lab Invest. 2018;98:999-1013 pubmed 出版商
Lively S, Lam D, Wong R, Schlichter L. Comparing Effects of Transforming Growth Factor β1 on Microglia From Rat and Mouse: Transcriptional Profiles and Potassium Channels. Front Cell Neurosci. 2018;12:115 pubmed 出版商
Schlereth K, Weichenhan D, Bauer T, Heumann T, Giannakouri E, Lipka D, et al. The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium. elife. 2018;7: pubmed 出版商
Huang L, Deng J, Xu W, Wang H, Shi L, Wu F, et al. CD8+ T cells with high TGF‑β1 expression cause lymph node fibrosis following HIV infection. Mol Med Rep. 2018;18:77-86 pubmed 出版商
Ottaviani S, Stebbing J, Frampton A, Zagorac S, Krell J, de Giorgio A, et al. TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nat Commun. 2018;9:1845 pubmed 出版商
Tsai C, Wu S, Kau H, Wei Y. Essential role of connective tissue growth factor (CTGF) in transforming growth factor-?1 (TGF-?1)-induced myofibroblast transdifferentiation from Graves' orbital fibroblasts. Sci Rep. 2018;8:7276 pubmed 出版商
Deng C, Lin Y, Qi X, He G, Zhang Y, Zhang H, et al. TNFRSF19 Inhibits TGF? Signaling through Interaction with TGF? Receptor Type I to Promote Tumorigenesis. Cancer Res. 2018;78:3469-3483 pubmed 出版商
Penke L, Speth J, Dommeti V, White E, Bergin I, Peters Golden M. FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis. J Clin Invest. 2018;128:2389-2405 pubmed 出版商
Schmidt A, Marabita F, Kiani N, Gross C, Johansson H, Elias S, et al. Time-resolved transcriptome and proteome landscape of human regulatory T cell (Treg) differentiation reveals novel regulators of FOXP3. BMC Biol. 2018;16:47 pubmed 出版商
Deshpande S, Abdollahi M, Wang M, Lanting L, Kato M, Natarajan R. Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy. Sci Rep. 2018;8:6954 pubmed 出版商
Zaiatz Bittencourt V, Finlay D, Gardiner C. Canonical TGF-β Signaling Pathway Represses Human NK Cell Metabolism. J Immunol. 2018;200:3934-3941 pubmed 出版商
Murillo Garzón V, Gorroño Etxebarria I, Akerfelt M, Puustinen M, Sistonen L, Nees M, et al. Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer. Nat Commun. 2018;9:1747 pubmed 出版商
Handler J, Cullis J, Avanzi A, Vucic E, Bar Sagi D. Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure. Oncogene. 2018;37:4334-4342 pubmed 出版商
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed 出版商
Rekik R, Smiti Khanfir M, Larbi T, Zamali I, Beldi Ferchiou A, Kammoun O, et al. Impaired TGF-β signaling in patients with active systemic lupus erythematosus is associated with an overexpression of IL-22. Cytokine. 2018;108:182-189 pubmed 出版商
Liu F, Chu C, Wei Q, Shi J, Li H, Dong N. Metformin ameliorates TGF-?1-induced osteoblastic differentiation of human aortic valve interstitial cells by inhibiting ?-catenin signaling. Biochem Biophys Res Commun. 2018;500:710-716 pubmed 出版商
Wang M, Chen D, Chen L, Cao G, Zhao H, Liu D, et al. Novel inhibitors of the cellular renin-angiotensin system components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis. Br J Pharmacol. 2018;175:2689-2708 pubmed 出版商
Knüppel L, Heinzelmann K, Lindner M, Hatz R, Behr J, Eickelberg O, et al. FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis. Respir Res. 2018;19:67 pubmed 出版商
Mallikarjuna P, Sitaram R, Landström M, Ljungberg B. VHL status regulates transforming growth factor-β signaling pathways in renal cell carcinoma. Oncotarget. 2018;9:16297-16310 pubmed 出版商
Corsuto L, Rother S, Koehler L, Bedini E, Moeller S, Schnabelrauch M, et al. Sulfation degree not origin of chondroitin sulfate derivatives modulates keratinocyte response. Carbohydr Polym. 2018;191:53-64 pubmed 出版商
Wu D, Lu P, Mi X, Miao J. Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis. Mol Hum Reprod. 2018;24:357-365 pubmed 出版商
Nakayama Y, Matsui S, Noda K, Yamazaki M, Iwai Y, Ganss B, et al. TGFβ1-induced Amelotin gene expression is downregulated by Bax expression in mouse gingival epithelial cells. J Oral Sci. 2018;60:232-241 pubmed 出版商
Gupta R, Somyajit K, Narita T, Maskey E, Stanlie A, Kremer M, et al. DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity. Cell. 2018;173:972-988.e23 pubmed 出版商
Jiang Y, Liu Y, Lu H, Sun S, Jin W, Wang X, et al. Epigenetic activation during T helper 17 cell differentiation is mediated by Tripartite motif containing 28. Nat Commun. 2018;9:1424 pubmed 出版商
Groppa E, Brkic S, Uccelli A, Wirth G, Korpisalo Pirinen P, Filippova M, et al. EphrinB2/EphB4 signaling regulates non-sprouting angiogenesis by VEGF. EMBO Rep. 2018;19: pubmed 出版商
Park S, Yang K, Park Y, Hong E, Hong C, Park J, et al. Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation. J Cancer Prev. 2018;23:1-9 pubmed 出版商
Leiphrakpam P, Brattain M, Black J, Wang J. TGFβ and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells. J Biol Chem. 2018;293:8242-8254 pubmed 出版商
Sharkey D, Glynn D, Schjenken J, Tremellen K, Robertson S. Interferon-gamma inhibits seminal plasma induction of colony-stimulating factor 2 in mouse and human reproductive tract epithelial cells. Biol Reprod. 2018;99:514-526 pubmed 出版商
Pincha N, Hajam E, Badarinath K, Batta S, Masudi T, Dey R, et al. PAI1 mediates fibroblast-mast cell interactions in skin fibrosis. J Clin Invest. 2018;128:1807-1819 pubmed 出版商
Nowsheen S, Aziz K, Aziz A, Deng M, Qin B, Luo K, et al. L3MBTL2 orchestrates ubiquitin signalling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage. Nat Cell Biol. 2018;20:455-464 pubmed 出版商
Geng L, Tang X, Zhou K, Wang D, Wang S, Yao G, et al. MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Cell Mol Immunol. 2018;: pubmed 出版商
Thomé R, Bonfanti A, Rasouli J, Mari E, Zhang G, Rostami A, et al. Chloroquine-treated dendritic cells require STAT1 signaling for their tolerogenic activity. Eur J Immunol. 2018;48:1228-1234 pubmed 出版商
Zhang B, Niu W, Dong H, Liu M, Luo Y, Li Z. Hypoxia induces endothelial‑mesenchymal transition in pulmonary vascular remodeling. Int J Mol Med. 2018;42:270-278 pubmed 出版商
Fraser H, Safinia N, Grageda N, Thirkell S, Lowe K, Fry L, et al. A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials. Mol Ther Methods Clin Dev. 2018;8:198-209 pubmed 出版商
Hu X, Kan H, Boye A, Jiang Y, Wu C, Yang Y. Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells. Oncol Lett. 2018;15:4867-4872 pubmed 出版商
Zila N, Bileck A, Muqaku B, Janker L, Eichhoff O, Cheng P, et al. Proteomics-based insights into mitogen-activated protein kinase inhibitor resistance of cerebral melanoma metastases. Clin Proteomics. 2018;15:13 pubmed 出版商
Beaulieu Leclerc V, Roy O, Santerre K, Proulx S. TGF-β1 promotes cell barrier function upon maturation of corneal endothelial cells. Sci Rep. 2018;8:4438 pubmed 出版商
Liu S, Iaria J, Simpson R, Zhu H. Ras enhances TGF-β signaling by decreasing cellular protein levels of its type II receptor negative regulator SPSB1. Cell Commun Signal. 2018;16:10 pubmed 出版商
Yang R, Yu T, Liu D, Shi S, Zhou Y. Hydrogen sulfide promotes immunomodulation of gingiva-derived mesenchymal stem cells via the Fas/FasL coupling pathway. Stem Cell Res Ther. 2018;9:62 pubmed 出版商
Sugiura H, Matsushita A, Futaya M, Teraoka A, Akiyama K, Usui N, et al. Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model. PLoS ONE. 2018;13:e0191706 pubmed 出版商
Wang J, Faiz A, Ge Q, Vermeulen C, Van der Velden J, Snibson K, et al. Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling. J Cell Mol Med. 2018;22:2826-2837 pubmed 出版商
Bozatzi P, Dingwell K, Wu K, Cooper F, Cummins T, Hutchinson L, et al. PAWS1 controls Wnt signalling through association with casein kinase 1α. EMBO Rep. 2018;19: pubmed 出版商
Merdrignac A, Angenard G, Allain C, Petitjean K, Bergeat D, Bellaud P, et al. A novel transforming growth factor beta-induced long noncoding RNA promotes an inflammatory microenvironment in human intrahepatic cholangiocarcinoma. Hepatol Commun. 2018;2:254-269 pubmed 出版商
Kobayashi K, Yoshioka T, Miyauchi J, Nakazawa A, Kiyokawa N, Maihara T, et al. Role of monocyte chemoattractant protein-1 in liver fibrosis with transient myeloproliferative disorder in down syndrome. Hepatol Commun. 2018;2:230-236 pubmed 出版商
Pleumeekers M, Nimeskern L, Koevoet J, Karperien M, Stok K, van Osch G. Trophic effects of adipose-tissue-derived and bone-marrow-derived mesenchymal stem cells enhance cartilage generation by chondrocytes in co-culture. PLoS ONE. 2018;13:e0190744 pubmed 出版商
Patalano S, Rodriguez Nieves J, Colaneri C, Cotellessa J, Almanza D, Zhilin Roth A, et al. CXCL12/CXCR4-Mediated Procollagen Secretion Is Coupled To Cullin-RING Ubiquitin Ligase Activation. Sci Rep. 2018;8:3499 pubmed 出版商
Wang R, Fu T, You K, Li S, Zhao N, Yang J, et al. Identification of a TGF-β-miR-195 positive feedback loop in hepatocytes and its deregulation in hepatoma cells. FASEB J. 2018;32:3936-3945 pubmed 出版商
Dave J, Mirabella T, Weatherbee S, Greif D. Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain. Dev Cell. 2018;44:665-678.e6 pubmed 出版商
Löfdahl A, Wenglén C, Rydell Törmänen K, Westergren Thorsson G, Larsson Callerfelt A. Effects of 5-Hydroxytryptamine Class 2 Receptor Antagonists on Bronchoconstriction and Pulmonary Remodeling Processes. Am J Pathol. 2018;188:1113-1119 pubmed 出版商
Gagnon L, Leduc M, Thibodeau J, Zhang M, Grouix B, Sarra Bournet F, et al. A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84. Am J Pathol. 2018;188:1132-1148 pubmed 出版商
Desancé M, Contentin R, Bertoni L, Gómez Leduc T, Branly T, Jacquet S, et al. Chondrogenic Differentiation of Defined Equine Mesenchymal Stem Cells Derived from Umbilical Cord Blood for Use in Cartilage Repair Therapy. Int J Mol Sci. 2018;19: pubmed 出版商
Losa M, Risolino M, Li B, Hart J, Quintana L, Grishina I, et al. Face morphogenesis is promoted by Pbx-dependent EMT via regulation of Snail1 during frontonasal prominence fusion. Development. 2018;145: pubmed 出版商
Kofler N, Corti F, Rivera Molina F, Deng Y, Toomre D, Simons M. The Rab-effector protein RABEP2 regulates endosomal trafficking to mediate vascular endothelial growth factor receptor-2 (VEGFR2)-dependent signaling. J Biol Chem. 2018;293:4805-4817 pubmed 出版商
Garikipati V, Singh S, Mohanram Y, Gupta A, Kapoor D, Nityanand S. Isolation and characterization of mesenchymal stem cells from human fetus heart. PLoS ONE. 2018;13:e0192244 pubmed 出版商
Wang F, Zachar V, Pennisi C, Fink T, Maeda Y, Emmersen J. Hypoxia Enhances Differentiation of Adipose Tissue-Derived Stem Cells toward the Smooth Muscle Phenotype. Int J Mol Sci. 2018;19: pubmed 出版商
Imamura M, Moon J, Chung K, Nakahira K, Muthukumar T, Shingarev R, et al. RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase. JCI Insight. 2018;3: pubmed 出版商
Chen L, Li J, Li Q, Li X, Gao Y, Hua X, et al. Overexpression of LncRNA AC067945.2 Down-Regulates Collagen Expression in Skin Fibroblasts and Possibly Correlates with the VEGF and Wnt Signalling Pathways. Cell Physiol Biochem. 2018;45:761-771 pubmed 出版商
Tian H, Huang J, Golzio C, Gao X, Hector Greene M, Katsanis N, et al. Endoglin interacts with VEGFR2 to promote angiogenesis. FASEB J. 2018;32:2934-2949 pubmed 出版商
Rosengren T, Larsen L, Pedersen L, Christensen S, Møller L. TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms. Cell Mol Life Sci. 2018;75:2663-2680 pubmed 出版商
Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, et al. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke. Cell Death Differ. 2018;25:1503-1516 pubmed 出版商
Zhou G, Jiang H, Yin Z, Liu Y, Zhang Q, Zhang C, et al. In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction. EBioMedicine. 2018;28:287-302 pubmed 出版商
Kodet O, Dvořánková B, Bendlova B, Sykorova V, Krajsova I, Stork J, et al. Microenvironment‑driven resistance to B‑Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts. Int J Mol Med. 2018;41:2687-2703 pubmed 出版商
Jia L, Tian Y, Chen Y, Zhang G. The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway. Onco Targets Ther. 2018;11:313-321 pubmed 出版商
Nishida J, Miyazono K, Ehata S. Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms. Oncogene. 2018;37:2197-2212 pubmed 出版商
Bellaye P, Shimbori C, Yanagihara T, Carlson D, Hughes P, Upagupta C, et al. Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis. Eur Respir J. 2018;51: pubmed 出版商
Zhang F, Liu G, Li D, Wei C, Hao J. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway. J Immunol. 2018;200:1618-1626 pubmed 出版商
Yamakawa T, Ohigashi H, Hashimoto D, Hayase E, Takahashi S, Miyazaki M, et al. Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease. Blood. 2018;: pubmed 出版商
Chen J, Wang C, Chen M. Curcumin inhibits TGF-β1-induced connective tissue growth factor expression through the interruption of Smad2 signaling in human gingival fibroblasts. J Formos Med Assoc. 2018;117:1115-1123 pubmed 出版商
Lin L, Li M, Lin L, Xu X, Jiang G, Wu L. FPPS mediates TGF-β1-induced non-small cell lung cancer cell invasion and the EMT process via the RhoA/Rock1 pathway. Biochem Biophys Res Commun. 2018;496:536-541 pubmed 出版商
Han S, Jung J, Im S, Lee S, Jang B, Park K, et al. Deficiency of primary cilia in kidney epithelial cells induces epithelial to mesenchymal transition. Biochem Biophys Res Commun. 2018;496:450-454 pubmed 出版商
Zhu J, Zhang Z, Zhang Y, Li W, Zheng W, Yu J, et al. MicroRNA-212 activates hepatic stellate cells and promotes liver fibrosis via targeting SMAD7. Biochem Biophys Res Commun. 2018;496:176-183 pubmed 出版商
Choi J, Pease D, Chen S, Zhang B, Phee H. P21-activated kinase 2 is essential in maintenance of peripheral Foxp3+ regulatory T cells. Immunology. 2018;154:309-321 pubmed 出版商
Cheng J, Yi Y, Chang H, Leung P. TGF-β1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation. Cell Signal. 2018;43:55-61 pubmed 出版商
Shin W, Jeon Y, Choi I, Kim Y. V-set and Ig domain-containing 4 (VSIG4)-expressing hepatic F4/80+ cells regulate oral antigen-specific responses in mouse. Eur J Immunol. 2018;48:632-643 pubmed 出版商
Reyes Reyes E, Aispuro I, Tavera Garcia M, Field M, Moore S, Ramos I, et al. LINE-1 couples EMT programming with acquisition of oncogenic phenotypes in human bronchial epithelial cells. Oncotarget. 2017;8:103828-103842 pubmed 出版商
Hardy S, Shinde A, Wang W, Wendt M, Geahlen R. Regulation of epithelial-mesenchymal transition and metastasis by TGF-?, P-bodies, and autophagy. Oncotarget. 2017;8:103302-103314 pubmed 出版商
Hanieh H, Masuda K, Metwally H, Chalise J, Mohamed M, Nyati K, et al. Arid5a stabilizes OX40 mRNA in murine CD4+ T cells by recognizing a stem-loop structure in its 3'UTR. Eur J Immunol. 2017;: pubmed 出版商
Gudey S, Sundar R, Heldin C, Bergh A, Landström M. Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGF? stimulation in cancer. Oncotarget. 2017;8:97703-97726 pubmed 出版商
Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed 出版商
Johnston C, Smyth D, Kodali R, White M, Harcus Y, Filbey K, et al. A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells. Nat Commun. 2017;8:1741 pubmed 出版商
Sahu S, Tiwari N, Pataskar A, Zhuang Y, Borisova M, Diken M, et al. FBXO32 promotes microenvironment underlying epithelial-mesenchymal transition via CtBP1 during tumour metastasis and brain development. Nat Commun. 2017;8:1523 pubmed 出版商
Yu F, Chen B, Fan X, Li G, Dong P, Zheng J. Epigenetically-Regulated MicroRNA-9-5p Suppresses the Activation of Hepatic Stellate Cells via TGFBR1 and TGFBR2. Cell Physiol Biochem. 2017;43:2242-2252 pubmed 出版商
Shibata A, Kuno M, Adachi R, Sato Y, Hattori H, Matsuda A, et al. Discovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy. PLoS ONE. 2017;12:e0186587 pubmed 出版商
Saito S, Zhuang Y, Shan B, Danchuk S, Luo F, Korfei M, et al. Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway. PLoS ONE. 2017;12:e0186615 pubmed 出版商
Wang W, Li P, Li W, Jiang J, Cui Y, Li S, et al. Osteopontin activates mesenchymal stem cells to repair skin wound. PLoS ONE. 2017;12:e0185346 pubmed 出版商
Wu S, Yang S, Chen H, Peng F, Yu H, Krepinsky J, et al. Dual roles of parathyroid hormone related protein in TGF-?1 signaling and fibronectin up-regulation in mesangial cells. Biosci Rep. 2017;37: pubmed 出版商
Sato Matsubara M, Matsubara T, Daikoku A, Okina Y, Longato L, Rombouts K, et al. Fibroblast growth factor 2 (FGF2) regulates cytoglobin expression and activation of human hepatic stellate cells via JNK signaling. J Biol Chem. 2017;292:18961-18972 pubmed 出版商
Turcotte M, Allard D, Mittal D, Bareche Y, Buisseret L, José V, et al. CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy. Cancer Res. 2017;77:5652-5663 pubmed 出版商
Qi Y, Wang N, He Y, Zhang J, Zou H, Zhang W, et al. Transforming growth factor-?1 signaling promotes epithelial-mesenchymal transition-like phenomena, cell motility, and cell invasion in synovial sarcoma cells. PLoS ONE. 2017;12:e0182680 pubmed 出版商
Chen Y, Wang D, Wu Y, Su D, Zhou T, Gai R, et al. MDM2 promotes epithelial-mesenchymal transition and metastasis of ovarian cancer SKOV3 cells. Br J Cancer. 2017;117:1192-1201 pubmed 出版商
Rodríguez Cortez V, Martínez Redondo P, Català Moll F, Rodriguez Ubreva J, Garcia Gomez A, Poorani Subramani G, et al. Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites. Sci Rep. 2017;7:7594 pubmed 出版商
Aström P, Juurikka K, Hadler Olsen E, Svineng G, Cervigne N, Coletta R, et al. The interplay of matrix metalloproteinase-8, transforming growth factor-?1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma. Br J Cancer. 2017;117:1007-1016 pubmed 出版商
Lee S, Kim D, Kang J, Kim E, Kim W, Youn H, et al. Surfactant Protein B Suppresses Lung Cancer Progression by Inhibiting Secretory Phospholipase A2 Activity and Arachidonic Acid Production. Cell Physiol Biochem. 2017;42:1684-1700 pubmed 出版商
Renard M, Muiño Mosquera L, Manalo E, Tufa S, Carlson E, Keene D, et al. Sex, pregnancy and aortic disease in Marfan syndrome. PLoS ONE. 2017;12:e0181166 pubmed 出版商
Kamata H, Tsukasaki Y, Sakai T, Ikebe R, Wang J, Jeffers A, et al. KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis. Sci Rep. 2017;7:4556 pubmed 出版商
Cheng J, Tseng C, Liao M, Peng C, Yu J, Chuang P, et al. Activation of hepatic stellate cells by the ubiquitin C-terminal hydrolase 1 protein secreted from hepatitis C virus-infected hepatocytes. Sci Rep. 2017;7:4448 pubmed 出版商
Caer C, Rouault C, Le Roy T, Poitou C, Aron Wisnewsky J, Torcivia A, et al. Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue. Sci Rep. 2017;7:3000 pubmed 出版商
Koo J, Nam M, Jung Y, Yoo J, Kim D, Kim G, et al. Anti-fibrogenic effect of PPAR-γ agonists in human intestinal myofibroblasts. BMC Gastroenterol. 2017;17:73 pubmed 出版商
Nguyen T, Sieg S. TGF-? inhibits IL-7-induced proliferation in memory but not naive human CD4+ T cells. J Leukoc Biol. 2017;102:499-506 pubmed 出版商
Bai L, Chang H, Cheng J, Klausen C, Chu G, Leung P, et al. SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells. Cell Signal. 2017;37:52-61 pubmed 出版商
Khakipoor S, Ophoven C, Schrödl Häußel M, Feuerstein M, Heimrich B, Deitmer J, et al. TGF-β signaling directly regulates transcription and functional expression of the electrogenic sodium bicarbonate cotransporter 1, NBCe1 (SLC4A4), via Smad4 in mouse astrocytes. Glia. 2017;65:1361-1375 pubmed 出版商
Kim E, Seo S, Shin H, Lee D, Kim J, Lee D. Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties. Clin Orthop Surg. 2017;9:239-248 pubmed 出版商
Zhao Q, Harbour S, Kolde R, Latorre I, Tun H, Schoeb T, et al. Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota. J Immunol. 2017;199:312-322 pubmed 出版商
Geng J, Yu S, Zhao H, Sun X, Li X, Wang P, et al. The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells. Nat Immunol. 2017;18:800-812 pubmed 出版商
Salvarani N, Maguy A, De Simone S, Miragoli M, Jousset F, Rohr S. TGF-β1 (Transforming Growth Factor-β1) Plays a Pivotal Role in Cardiac Myofibroblast Arrhythmogenicity. Circ Arrhythm Electrophysiol. 2017;10:e004567 pubmed 出版商
Ko J, Chae M, Lee J, Lee E, Yoon J. Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. Invest Ophthalmol Vis Sci. 2017;58:2544-2553 pubmed 出版商
Calvier L, Chouvarine P, Legchenko E, Hoffmann N, Geldner J, Borchert P, et al. PPARγ Links BMP2 and TGFβ1 Pathways in Vascular Smooth Muscle Cells, Regulating Cell Proliferation and Glucose Metabolism. Cell Metab. 2017;25:1118-1134.e7 pubmed 出版商
Singh R, Miao T, Symonds A, Omodho B, Li S, Wang P. Egr2 and 3 Inhibit T-bet-Mediated IFN-? Production in T Cells. J Immunol. 2017;198:4394-4402 pubmed 出版商
Zhao Z, Liu H, Sun X, Guo T, Shen L, Tao Y, et al. Levistilide A inhibits angiogenesis in liver fibrosis via vascular endothelial growth factor signaling pathway. Exp Biol Med (Maywood). 2017;242:974-985 pubmed 出版商
Zhang Y. Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/?-catenin signaling. Biochem Biophys Res Commun. 2017;488:679-684 pubmed 出版商
Shiokawa A, Kotaki R, Takano T, Nakajima Adachi H, Hachimura S. Mesenteric lymph node CD11b- CD103+ PD-L1High dendritic cells highly induce regulatory T cells. Immunology. 2017;152:52-64 pubmed 出版商
Kathiriya J, Nakra N, Nixon J, Patel P, Vaghasiya V, Alhassani A, et al. Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis. Cell Death Discov. 2017;3:17010 pubmed 出版商
Whelan K, Chandramouleeswaran P, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, et al. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance. Oncogene. 2017;36:4843-4858 pubmed 出版商
Zhou D, Zhang L, Sun W, Guan W, Lin Q, Ren W, et al. Cytidine monophosphate kinase is inhibited by the TGF-β signalling pathway through the upregulation of miR-130b-3p in human epithelial ovarian cancer. Cell Signal. 2017;35:197-207 pubmed 出版商
Dimitrova Y, Gruber A, Mittal N, Ghosh S, Dimitriades B, Mathow D, et al. TFAP2A is a component of the ZEB1/2 network that regulates TGFB1-induced epithelial to mesenchymal transition. Biol Direct. 2017;12:8 pubmed 出版商
Ghatak S, Hascall V, Markwald R, Feghali Bostwick C, Artlett C, Gooz M, et al. Transforming growth factor ?1 (TGF?1)-induced CD44V6-NOX4 signaling in pathogenesis of idiopathic pulmonary fibrosis. J Biol Chem. 2017;292:10490-10519 pubmed 出版商
Pan F, Xiang H, Yan J, Hong L, Zhang L, Liu Y, et al. Dendritic Cells from Rheumatoid Arthritis Patient Peripheral Blood Induce Th17 Cell Differentiation via miR-363/Integrin ?v/TGF-? Axis. Scand J Immunol. 2017;85:441-449 pubmed 出版商
McCauley K, Hawkins F, Serra M, Thomas D, JACOB A, Kotton D. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 2017;20:844-857.e6 pubmed 出版商
Desai K, Aiyappa R, Prabhu J, Nair M, Lawrence P, Korlimarla A, et al. HR+HER2- breast cancers with growth factor receptor-mediated EMT have a poor prognosis and lapatinib downregulates EMT in MCF-7 cells. Tumour Biol. 2017;39:1010428317695028 pubmed 出版商
Pagiatakis C, Sun D, Tobin S, Miyake T, McDermott J. TGFβ-TAZ/SRF signalling regulates vascular smooth muscle cell differentiation. FEBS J. 2017;284:1644-1656 pubmed 出版商
Siddiqui A, Vazakidou M, Schwab A, Napoli F, Fernandez Molina C, Rapa I, et al. Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells. J Pathol. 2017;242:221-233 pubmed 出版商
Ruiz Carpio V, Sandoval P, Aguilera A, Albar Vizcaino P, Perez Lozano M, González Mateo G, et al. Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients. Sci Rep. 2017;7:44941 pubmed 出版商
Kamio K, Azuma A, Usuki J, Matsuda K, Inomata M, Nishijima N, et al. XPLN is modulated by HDAC inhibitors and negatively regulates SPARC expression by targeting mTORC2 in human lung fibroblasts. Pulm Pharmacol Ther. 2017;44:61-69 pubmed 出版商
Iizuka D, Sasatani M, Barcellos Hoff M, Kamiya K. Hydrogen Peroxide Enhances TGF?-mediated Epithelial-to-Mesenchymal Transition in Human Mammary Epithelial MCF-10A Cells. Anticancer Res. 2017;37:987-995 pubmed
Tachida Y, Izumi N, Sakurai T, Kobayashi H. Mutual interaction between endothelial cells and mural cells enhances BMP9 signaling in endothelial cells. Biol Open. 2017;6:370-380 pubmed 出版商
Loayza Puch F, Rooijers K, Zijlstra J, Moumbeini B, Zaal E, Oude Vrielink J, et al. TGFβ1-induced leucine limitation uncovered by differential ribosome codon reading. EMBO Rep. 2017;18:549-557 pubmed 出版商
Hammers D, Merscham Banda M, Hsiao J, ENGST S, Hartman J, Sweeney H. Supraphysiological levels of GDF11 induce striated muscle atrophy. EMBO Mol Med. 2017;9:531-544 pubmed 出版商
Bae K, Seo J, Jung Y, Seo H, Kang S, Jeon H, et al. Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor γ Agonist, Attenuates Renal Fibrosis Caused by Unilateral Ureteral Obstruction in Mice. Endocrinol Metab (Seoul). 2017;32:115-123 pubmed 出版商
Zhao W, Yan J, Gao L, Zhao J, Zhao C, Gao C, et al. Cdk5 is required for the neuroprotective effect of transforming growth factor-?1 against cerebral ischemia-reperfusion. Biochem Biophys Res Commun. 2017;485:775-781 pubmed 出版商
Pap D, Sziksz E, Kiss Z, Rokonay R, Veres Székely A, Lippai R, et al. Microarray Analysis Reveals Increased Expression of Matrix Metalloproteases and Cytokines of Interleukin-20 Subfamily in the Kidneys of Neonate Rats Underwent Unilateral Ureteral Obstruction: A Potential Role of IL-24 in the Regulation of Inflammatio. Kidney Blood Press Res. 2017;42:16-32 pubmed 出版商
Rynne Vidal A, Au Yeung C, Jimenez Heffernan J, Perez Lozano M, Cremades Jimeno L, Bárcena C, et al. Mesothelial-to-mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer. J Pathol. 2017;242:140-151 pubmed 出版商
Mondanelli G, Bianchi R, Pallotta M, Orabona C, Albini E, Iacono A, et al. A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells. Immunity. 2017;46:233-244 pubmed 出版商
Boswell B, Korol A, West Mays J, Musil L. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell. 2017;28:907-921 pubmed 出版商
Sasahara A, Tominaga K, Nishimura T, Yano M, Kiyokawa E, Noguchi M, et al. An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells. Oncotarget. 2017;8:24869-24881 pubmed 出版商
Hu Y, Lao L, Mao J, Jin W, Luo H, Charpentier T, et al. Armc5 deletion causes developmental defects and compromises T-cell immune responses. Nat Commun. 2017;8:13834 pubmed 出版商
Sakaguchi K, Katagiri W, Osugi M, Kawai T, Sugimura Wakayama Y, Hibi H. Periodontal tissue regeneration using the cytokine cocktail mimicking secretomes in the conditioned media from human mesenchymal stem cells. Biochem Biophys Res Commun. 2017;484:100-106 pubmed 出版商
Gopal S, Veracini L, Grall D, Butori C, Schaub S, Audebert S, et al. Fibronectin-guided migration of carcinoma collectives. Nat Commun. 2017;8:14105 pubmed 出版商
Brethour D, Mehrabian M, Williams D, Wang X, Ghodrati F, Ehsani S, et al. A ZIP6-ZIP10 heteromer controls NCAM1 phosphorylation and integration into focal adhesion complexes during epithelial-to-mesenchymal transition. Sci Rep. 2017;7:40313 pubmed 出版商
Lécuyer M, Saint Laurent O, Bourbonnière L, Larouche S, Larochelle C, Michel L, et al. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis. Proc Natl Acad Sci U S A. 2017;114:E524-E533 pubmed 出版商
Yu C, Kornmuller A, Brown C, Hoare T, Flynn L. Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion. Biomaterials. 2017;120:66-80 pubmed 出版商
MikuÅ‚a Pietrasik J, Uruski P, SosiÅ„ska P, Maksin K, Piotrowska Kempisty H, KuciÅ„ska M, et al. Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases. Cell Death Dis. 2016;7:e2565 pubmed 出版商
Okada Y, Shirai K, Miyajima M, Reinach P, Yamanaka O, Sumioka T, et al. Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas. PLoS ONE. 2016;11:e0167200 pubmed 出版商
Suzuki Yamazaki N, Yanobu Takanashi R, Okamura T, Takaki S. IL-10 production in murine IgM+ CD138hi cells is driven by Blimp-1 and downregulated in class-switched cells. Eur J Immunol. 2017;47:493-503 pubmed 出版商
Vaidyanathan B, Chaudhry A, Yewdell W, Angeletti D, Yen W, Wheatley A, et al. The aryl hydrocarbon receptor controls cell-fate decisions in B cells. J Exp Med. 2017;214:197-208 pubmed 出版商
Rafiq N, Lieu Z, Jiang T, Yu C, Matsudaira P, Jones G, et al. Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO. J Cell Biol. 2017;216:181-197 pubmed 出版商
Kusumoto H, Shintani Y, Kanzaki R, Kawamura T, Funaki S, Minami M, et al. Podocalyxin influences malignant potential by controlling epithelial-mesenchymal transition in lung adenocarcinoma. Cancer Sci. 2017;108:528-535 pubmed 出版商
Horikiri T, Hara H, Saito N, Araya J, Takasaka N, Utsumi H, et al. Increased levels of prostaglandin E-major urinary metabolite (PGE-MUM) in chronic fibrosing interstitial pneumonia. Respir Med. 2017;122:43-50 pubmed 出版商
Baarsma H, Skronska Wasek W, Mutze K, Ciolek F, Wagner D, John Schuster G, et al. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J Exp Med. 2017;214:143-163 pubmed 出版商
Bayin N, Ma L, Thomas C, Baitalmal R, Sure A, Fansiwala K, et al. Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-β Small Molecule Inhibitor. Neoplasia. 2016;18:795-805 pubmed 出版商
Griffin M, Ibrahim A, Seifalian A, Butler P, Kalaskar D, Ferretti P. Chemical group-dependent plasma polymerisation preferentially directs adipose stem cell differentiation towards osteogenic or chondrogenic lineages. Acta Biomater. 2017;50:450-461 pubmed 出版商
Guo D, Duan X, Regalado E, Mellor Crummey L, Kwartler C, Kim D, et al. Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease. Am J Hum Genet. 2017;100:21-30 pubmed 出版商
Li Y, Chang J, Lee L, Fan K, Lu Y, Li Y, et al. GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway. Oncotarget. 2017;8:1508-1528 pubmed 出版商
Huang Y, Huang Q, Su H, Mai X, Feng E, Cao Z, et al. TAR DNA-binding protein 43 inhibits inflammatory response and protects chondrocyte function by modulating RACK1 expression in osteoarthritis. Biomed Pharmacother. 2017;85:362-371 pubmed 出版商
Chanda D, Kurundkar A, Rangarajan S, Locy M, Bernard K, Sharma N, et al. Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis. Sci Rep. 2016;6:37445 pubmed 出版商
Chaudhury A, Cheema S, Fachini J, Kongchan N, Lu G, Simon L, et al. CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT. Nat Commun. 2016;7:13362 pubmed 出版商
El Agha E, Moiseenko A, Kheirollahi V, De Langhe S, Crnkovic S, Kwapiszewska G, et al. Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis. Cell Stem Cell. 2017;20:261-273.e3 pubmed 出版商
Zhao J, Liu J, Lee J, Zhang W, Kandouz M, VanHecke G, et al. TGF-?/SMAD3 Pathway Stimulates Sphingosine-1 Phosphate Receptor 3 Expression: IMPLICATION OF SPHINGOSINE-1 PHOSPHATE RECEPTOR 3 IN LUNG ADENOCARCINOMA PROGRESSION. J Biol Chem. 2016;291:27343-27353 pubmed 出版商
Le M, Haddad D, Ling A, Li C, So C, Chopra A, et al. Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching. Sci Rep. 2016;6:37215 pubmed 出版商
Terashima M, Tange S, Ishimura A, Suzuki T. MEG3 Long Noncoding RNA Contributes to the Epigenetic Regulation of Epithelial-Mesenchymal Transition in Lung Cancer Cell Lines. J Biol Chem. 2017;292:82-99 pubmed 出版商
Hu B, Shi C, Lei R, Lu D, Luo W, Qin S, et al. Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin. Sci Rep. 2016;6:36436 pubmed 出版商
JENKINS L, Singh P, Varadaraj A, Lee N, Shah S, Flores H, et al. Altering the Proteoglycan State of Transforming Growth Factor ? Type III Receptor (T?RIII)/Betaglycan Modulates Canonical Wnt/?-Catenin Signaling. J Biol Chem. 2016;291:25716-25728 pubmed
Gamboa Castro M, Leggett S, Wong I. Clustering and jamming in epithelial-mesenchymal co-cultures. Soft Matter. 2016;12:8327-8337 pubmed
VanOudenhove J, Medina R, Ghule P, Lian J, Stein J, Zaidi S, et al. Transient RUNX1 Expression during Early Mesendodermal Differentiation of hESCs Promotes Epithelial to Mesenchymal Transition through TGFB2 Signaling. Stem Cell Reports. 2016;7:884-896 pubmed 出版商
Pai C, Walsh C, Fruman D. Context-Specific Function of S6K2 in Th Cell Differentiation. J Immunol. 2016;197:3049-3058 pubmed
Xiao X, Senavirathna L, Gou X, Huang C, Liang Y, Liu L. EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis. Physiol Rep. 2016;4: pubmed 出版商
Boyan B, Hyzy S, Pan Q, Scott K, Coutts R, Healey R, et al. 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats. PLoS ONE. 2016;11:e0161782 pubmed 出版商
Park I, Kang J, Shin J, Lee H. Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-?1 in Airway Epithelium. PLoS ONE. 2016;11:e0162058 pubmed 出版商
Josowitz R, Mulero Navarro S, Rodriguez N, Falce C, Cohen N, Ullian E, et al. Autonomous and Non-autonomous Defects Underlie Hypertrophic Cardiomyopathy in BRAF-Mutant hiPSC-Derived Cardiomyocytes. Stem Cell Reports. 2016;7:355-369 pubmed 出版商
Liu Z, Ning G, Xu R, Cao Y, Meng A, Wang Q. Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation. Nat Commun. 2016;7:12603 pubmed 出版商
Jiao J, Xiong W, Wang L, Yang J, Qiu P, Hirai H, et al. Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves. EBioMedicine. 2016;10:282-90 pubmed 出版商
Miller C, Pjanic M, Wang T, Nguyen T, Cohain A, Lee J, et al. Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci. Nat Commun. 2016;7:12092 pubmed 出版商
Mehrabian M, Brethour D, Williams D, Wang H, Arnould H, Schneider B, et al. Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue. PLoS ONE. 2016;11:e0156779 pubmed 出版商
Schrøder M, Melum G, Landsverk O, Bujko A, Yaqub S, Gran E, et al. CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits. PLoS ONE. 2016;11:e0157387 pubmed 出版商
Li Q, Sodroski C, Lowey B, Schweitzer C, Cha H, Zhang F, et al. Hepatitis C virus depends on E-cadherin as an entry factor and regulates its expression in epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2016;113:7620-5 pubmed 出版商
Tang F, Hansbro P, Burgess J, Ammit A, Baines K, Oliver B. A novel immunomodulatory function of neutrophils on rhinovirus-activated monocytes in vitro. Thorax. 2016;71:1039-1049 pubmed 出版商
Ohno S, Yokoi H, Mori K, Kasahara M, Kuwahara K, Fujikura J, et al. Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure. Sci Rep. 2016;6:27192 pubmed 出版商
Bourcy M, Suarez Carmona M, Lambert J, Francart M, Schroeder H, Delierneux C, et al. Tissue Factor Induced by Epithelial-Mesenchymal Transition Triggers a Procoagulant State That Drives Metastasis of Circulating Tumor Cells. Cancer Res. 2016;76:4270-82 pubmed 出版商
O Connor J, Mistry K, Detweiler D, Wang C, Gomez E. Cell-cell contact and matrix adhesion promote αSMA expression during TGFβ1-induced epithelial-myofibroblast transition via Notch and MRTF-A. Sci Rep. 2016;6:26226 pubmed 出版商
Boehme S, Franz Bacon K, DiTirro D, Ly T, Bacon K. MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis. PLoS ONE. 2016;11:e0154874 pubmed 出版商
Kang Y, Roife D, Lee Y, Lv H, Suzuki R, Ling J, et al. Transforming Growth Factor-? Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors. Clin Cancer Res. 2016;22:4934-4946 pubmed
Schmidt A, Zhang X, Joshi R, Iqbal S, Wahlund C, Gabrielsson S, et al. Human macrophages induce CD4(+)Foxp3(+) regulatory T cells via binding and re-release of TGF-?. Immunol Cell Biol. 2016;94:747-62 pubmed 出版商
Kaylan K, Ermilova V, Yada R, Underhill G. Combinatorial microenvironmental regulation of liver progenitor differentiation by Notch ligands, TGFβ, and extracellular matrix. Sci Rep. 2016;6:23490 pubmed 出版商
Flynn R, Paz K, Du J, Reichenbach D, Taylor P, Panoskaltsis Mortari A, et al. Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism. Blood. 2016;127:2144-54 pubmed 出版商
Pedroza Pacheco I, Shah D, Domogala A, Luevano M, Blundell M, Jackson N, et al. Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation. Sci Rep. 2016;6:22097 pubmed 出版商
Schmidt A, Eriksson M, Shang M, Weyd H, Tegner J. Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate. PLoS ONE. 2016;11:e0148474 pubmed 出版商
Lu G, Duan J, Shu S, Wang X, Gao L, Guo J, et al. Ligase I and ligase III mediate the DNA double-strand break ligation in alternative end-joining. Proc Natl Acad Sci U S A. 2016;113:1256-60 pubmed 出版商
Masani S, Han L, Meek K, Yu K. Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination. Proc Natl Acad Sci U S A. 2016;113:1261-6 pubmed 出版商
Miyashita A, Fukushima S, Nakahara S, Kubo Y, Tokuzumi A, Yamashita J, et al. Immunotherapy against Metastatic Melanoma with Human iPS Cell-Derived Myeloid Cell Lines Producing Type I Interferons. Cancer Immunol Res. 2016;4:248-58 pubmed 出版商
Fan M, Zhu Q, Li H, Ra H, Majumdar S, Gulick D, et al. Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice. J Biol Chem. 2016;291:8070-89 pubmed 出版商
Sasaki C, Chen G, Munk R, Eitan E, Martindale J, Longo D, et al. p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice. Eur J Immunol. 2016;46:212-22 pubmed 出版商
Coram R, Stillwagon S, Guggilam A, Jenkins M, Swanson M, Ladd A. Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev Biol. 2015;15:36 pubmed 出版商
Malagola E, Teunissen M, van der Laan L, Verstegen M, Schotanus B, van Steenbeek F, et al. Characterization and Comparison of Canine Multipotent Stromal Cells Derived from Liver and Bone Marrow. Stem Cells Dev. 2016;25:139-50 pubmed 出版商
Nakatsukasa H, Zhang D, Maruyama T, Chen H, Cui K, Ishikawa M, et al. The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. Nat Immunol. 2015;16:1077-84 pubmed 出版商
Brusgard J, Choe M, Chumsri S, Renoud K, MacKerell A, Sudol M, et al. RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells. Oncotarget. 2015;6:28132-50 pubmed 出版商
Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt Ulms G. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE. 2015;10:e0133741 pubmed 出版商
Roach K, Feghali Bostwick C, Amrani Y, Bradding P. Lipoxin A4 Attenuates Constitutive and TGF-β1-Dependent Profibrotic Activity in Human Lung Myofibroblasts. J Immunol. 2015;195:2852-60 pubmed 出版商
Lian M, Luo W, Sui Y, Li Z, Hua J. Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-γ Expression. PLoS ONE. 2015;10:e0132741 pubmed 出版商
Sahu S, Garding A, Tiwari N, Thakurela S, Toedling J, Gebhard S, et al. JNK-dependent gene regulatory circuitry governs mesenchymal fate. EMBO J. 2015;34:2162-81 pubmed 出版商
Fujita T, Chiwaki F, Takahashi R, Aoyagi K, Yanagihara K, Nishimura T, et al. Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells. PLoS ONE. 2015;10:e0130808 pubmed 出版商
Singh I, Ozturk N, Cordero J, Mehta A, Hasan D, Cosentino C, et al. High mobility group protein-mediated transcription requires DNA damage marker γ-H2AX. Cell Res. 2015;25:837-50 pubmed 出版商
Pang M, Georgoudaki A, Lambut L, Johansson J, Tabor V, Hagikura K, et al. TGF-β1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene. 2016;35:748-60 pubmed 出版商
Harris T, McGargill M. Drak2 Does Not Regulate TGF-β Signaling in T Cells. PLoS ONE. 2015;10:e0123650 pubmed 出版商
Kuk H, Hutchenreuther J, Murphy Marshman H, Carter D, Leask A. 5Z-7-Oxozeanol Inhibits the Effects of TGFβ1 on Human Gingival Fibroblasts. PLoS ONE. 2015;10:e0123689 pubmed 出版商
Rojas Fernandez A, Herhaus L, MacArtney T, Lachaud C, Hay R, Sapkota G. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep. 2015;5:9811 pubmed 出版商
Sun Y, Deng W, Geng L, Zhang L, Liu R, Chen W, et al. Mesenchymal stem cells from patients with rheumatoid arthritis display impaired function in inhibiting Th17 cells. J Immunol Res. 2015;2015:284215 pubmed 出版商
Kaushansky N, Eisenstein M, Boura Halfon S, Hansen B, Nielsen C, Milo R, et al. Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease. J Biol Chem. 2015;290:15260-78 pubmed 出版商
Young K, Tweedie E, Conley B, Ames J, FitzSimons M, Brooks P, et al. BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses. PLoS ONE. 2015;10:e0122892 pubmed 出版商
Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, et al. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med. 2015;21:530-6 pubmed 出版商
Giraldo C, Álvarez M, Carmona J. Effects of sodium citrate and acid citrate dextrose solutions on cell counts and growth factor release from equine pure-platelet rich plasma and pure-platelet rich gel. BMC Vet Res. 2015;11:60 pubmed 出版商
Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol. 2015;16:6 pubmed 出版商
Cruet Hennequart S, Drougard C, Shaw G, Legendre F, Demoor M, Barry F, et al. Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE. 2015;10:e0119334 pubmed 出版商
Yu D, Zhang C, Zhao S, Zhang S, Zhang H, Cai S, et al. The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway. Acta Pharmacol Sin. 2015;36:473-82 pubmed 出版商
Cho W, Kim Y, Kim J, Park S, Park D, Kim B, et al. Suppressor of cytokine signaling 1 is a positive regulator of TGF-β-induced prostaglandin production in human follicular dendritic cell-like cells. J Immunol. 2015;194:4287-97 pubmed 出版商
Jia D, Duan F, Peng P, Sun L, Ruan Y, Gu J. Pyrroloquinoline-quinone suppresses liver fibrogenesis in mice. PLoS ONE. 2015;10:e0121939 pubmed 出版商
Schmitt Ney M, Camussi G. The PAX3-FOXO1 fusion protein present in rhabdomyosarcoma interferes with normal FOXO activity and the TGF-β pathway. PLoS ONE. 2015;10:e0121474 pubmed 出版商
Wöltje K, Jabs M, Fischer A. Serum induces transcription of Hey1 and Hey2 genes by Alk1 but not Notch signaling in endothelial cells. PLoS ONE. 2015;10:e0120547 pubmed 出版商
Mu Y, Zang G, Engström U, Busch C, Landström M. TGFβ-induced phosphorylation of Par6 promotes migration and invasion in prostate cancer cells. Br J Cancer. 2015;112:1223-31 pubmed 出版商
Narcisi R, Cleary M, Brama P, Hoogduijn M, Tüysüz N, ten Berge D, et al. Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. Stem Cell Reports. 2015;4:459-72 pubmed 出版商
Canavan J, Scotta C, Vossenkamper A, Goldberg R, Elder M, Shoval I, et al. Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease. Gut. 2016;65:584-94 pubmed 出版商
Kinugasa H, Whelan K, Tanaka K, Natsuizaka M, Long A, Guo A, et al. Mitochondrial SOD2 regulates epithelial-mesenchymal transition and cell populations defined by differential CD44 expression. Oncogene. 2015;34:5229-39 pubmed 出版商
Ghiabi P, Jiang J, Pasquier J, Maleki M, Abu Kaoud N, Halabi N, et al. Breast cancer cells promote a notch-dependent mesenchymal phenotype in endothelial cells participating to a pro-tumoral niche. J Transl Med. 2015;13:27 pubmed 出版商
Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, et al. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci. 2015;56:1051-62 pubmed 出版商
Haffner Luntzer M, Heilmann A, Rapp A, Beie S, Schinke T, Amling M, et al. Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice. PLoS ONE. 2014;9:e116282 pubmed 出版商
Waight J, Takai S, Marelli B, Qin G, Hance K, Zhang D, et al. Cutting edge: epigenetic regulation of Foxp3 defines a stable population of CD4+ regulatory T cells in tumors from mice and humans. J Immunol. 2015;194:878-82 pubmed 出版商
Woeller C, O Loughlin C, Roztocil E, Feldon S, Phipps R. Salinomycin and other polyether ionophores are a new class of antiscarring agent. J Biol Chem. 2015;290:3563-75 pubmed 出版商
Nguyen L, Pan J, Dinh T, Hadeiba H, O Hara E, Ebtikar A, et al. Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. Nat Immunol. 2015;16:207-213 pubmed 出版商
Galvagni F, Lentucci C, Neri F, Dettori D, De Clemente C, Orlandini M, et al. Snai1 promotes ESC exit from the pluripotency by direct repression of self-renewal genes. Stem Cells. 2015;33:742-50 pubmed 出版商
Gordian E, Li J, Pevzner Y, Mediavilla Varela M, Luddy K, Ohaegbulam K, et al. Transforming growth factor β signaling overcomes dasatinib resistance in lung cancer. PLoS ONE. 2014;9:e114131 pubmed 出版商
Wang J, Cao Z, Zhang X, Nakamura M, Sun M, Hartman J, et al. Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development. Cancer Res. 2015;75:306-15 pubmed 出版商
Rutz S, Kayagaki N, Phung Q, Eidenschenk C, Noubade R, Wang X, et al. Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature. 2015;518:417-21 pubmed 出版商
Duan L, Qi J, Kong X, Huang T, Qian X, Xu D, et al. MiR-133 modulates TGF-β1-induced bladder smooth muscle cell hypertrophic and fibrotic response: implication for a role of microRNA in bladder wall remodeling caused by bladder outlet obstruction. Cell Signal. 2015;27:215-27 pubmed 出版商
Choi J, Park H, Kim T, Jeong Y, Oh M, Hyeon T, et al. Engineered collagen hydrogels for the sustained release of biomolecules and imaging agents: promoting the growth of human gingival cells. Int J Nanomedicine. 2014;9:5189-201 pubmed 出版商
Presnell S, Al Attar A, Cichocki F, Miller J, Lutz C. Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs. Genes Immun. 2015;16:89-98 pubmed 出版商
Eun S, Lee S, Xu Y, Croft M. 4-1BB ligand signaling to T cells limits T cell activation. J Immunol. 2015;194:134-41 pubmed 出版商
Li J, Ballim D, Rodriguez M, Cui R, Goding C, Teng H, et al. The anti-proliferative function of the TGF-β1 signaling pathway involves the repression of the oncogenic TBX2 by its homologue TBX3. J Biol Chem. 2014;289:35633-43 pubmed 出版商
Bohnsack R, Warejcka D, Wang L, Gillespie S, Bernstein A, Twining S, et al. Expression of insulin-like growth factor 2 receptor in corneal keratocytes during differentiation and in response to wound healing. Invest Ophthalmol Vis Sci. 2014;55:7697-708 pubmed 出版商
Jolly L, Stavrou A, Vanderstoken G, Meliopoulos V, Habgood A, Tatler A, et al. Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation. J Biol Chem. 2014;289:35246-63 pubmed 出版商
Kuang D, Xiao X, Zhao Q, Chen M, Li X, Liu R, et al. B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest. 2014;124:4657-67 pubmed 出版商
Xiao G, Liu I, Cheng C, Chang C, Lee Y, Cheng W, et al. Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy. PLoS ONE. 2014;9:e106538 pubmed 出版商
Chen K, Hsu H, Lee C, Yen T, Ko Y, Yang C, et al. The AMPK agonist AICAR inhibits TGF-β1 induced activation of kidney myofibroblasts. PLoS ONE. 2014;9:e106554 pubmed 出版商
Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, et al. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE. 2014;9:e106673 pubmed 出版商
Tobar N, Toyos M, Urra C, Méndez N, Arancibia R, Smith P, et al. c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells. BMC Cancer. 2014;14:640 pubmed 出版商
Cheng T, Hu C, Yang H, Cao L, An J. Transforming growth factor-β-induced miR‑143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo. Int J Oncol. 2014;45:1977-88 pubmed 出版商
Pessina P, Cabrera D, Morales M, Riquelme C, Gutiérrez J, Serrano A, et al. Novel and optimized strategies for inducing fibrosis in vivo: focus on Duchenne Muscular Dystrophy. Skelet Muscle. 2014;4:7 pubmed 出版商
Zhou Y, Xiong M, Niu J, Sun Q, Su W, Zen K, et al. Secreted fibroblast-derived miR-34a induces tubular cell apoptosis in fibrotic kidney. J Cell Sci. 2014;127:4494-506 pubmed 出版商
Scherz Shouval R, Santagata S, Mendillo M, Sholl L, Ben Aharon I, Beck A, et al. The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy. Cell. 2014;158:564-78 pubmed 出版商
Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, et al. Role of Blimp-1 in programing Th effector cells into IL-10 producers. J Exp Med. 2014;211:1807-19 pubmed 出版商
Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, et al. The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor ?t (ROR?t) in Th17 cells. J Biol Chem. 2014;289:25546-55 pubmed 出版商
Pan C, Kumar S, Shah N, Hoyt D, Hawinkels L, Mythreye K, et al. Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis. J Biol Chem. 2014;289:25486-96 pubmed 出版商
Okada Y, Shirai K, Reinach P, Kitano Izutani A, Miyajima M, Flanders K, et al. TRPA1 is required for TGF-β signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma. Lab Invest. 2014;94:1030-41 pubmed 出版商
Chen L, Munoz Antonia T, Cress W. Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines. PLoS ONE. 2014;9:e101040 pubmed 出版商
Mercer F, Khaitan A, Kozhaya L, Aberg J, Unutmaz D. Differentiation of IL-17-producing effector and regulatory human T cells from lineage-committed naive precursors. J Immunol. 2014;193:1047-54 pubmed 出版商
Hardin H, Guo Z, Shan W, Montemayor Garcia C, Asioli S, Yu X, et al. The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression. Am J Pathol. 2014;184:2342-54 pubmed 出版商
Lim M, Ahn J, Yi J, Kim M, Son A, Lee S, et al. Induction of galectin-1 by TGF-?1 accelerates fibrosis through enhancing nuclear retention of Smad2. Exp Cell Res. 2014;326:125-35 pubmed 出版商
Arts M, Baron M, Chokr N, Fritzler M, Servant M. Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor. PLoS ONE. 2014;9:e100035 pubmed 出版商
Santhekadur P, Akiel M, Emdad L, Gredler R, Srivastava J, Rajasekaran D, et al. Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGF? signaling. FEBS Open Bio. 2014;4:353-61 pubmed 出版商
Liu Y, Kimura K, Orita T, Teranishi S, Suzuki K, Sonoda K. Inhibition by all-trans-retinoic acid of transforming growth factor-β-induced collagen gel contraction mediated by human tenon fibroblasts. Invest Ophthalmol Vis Sci. 2014;55:4199-205 pubmed 出版商
Okabe H, Delgado E, Lee J, Yang J, Kinoshita H, Hayashi H, et al. Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma. PLoS ONE. 2014;9:e98817 pubmed 出版商
Zafar A, Wu F, Hardy K, Li J, Tu W, McCuaig R, et al. Chromatinized protein kinase C-? directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Mol Cell Biol. 2014;34:2961-80 pubmed 出版商
Togashi Y, Sakamoto H, Hayashi H, Terashima M, De Velasco M, Fujita Y, et al. Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer. Mol Cancer. 2014;13:126 pubmed 出版商
Salvo E, Garasa S, Dotor J, Morales X, Pelaez R, Altevogt P, et al. Combined targeting of TGF-?1 and integrin ?3 impairs lymph node metastasis in a mouse model of non-small-cell lung cancer. Mol Cancer. 2014;13:112 pubmed 出版商
Matthews A, Husain S, Chaudhuri J. Binding of AID to DNA does not correlate with mutator activity. J Immunol. 2014;193:252-7 pubmed 出版商
Choi S, Kim B, Robinson J, Fink S, Yan M, Sporn M, et al. Synthetic triterpenoid induces 15-PGDH expression and suppresses inflammation-driven colon carcinogenesis. J Clin Invest. 2014;124:2472-82 pubmed 出版商
Desai L, Zhou Y, Estrada A, Ding Q, Cheng G, Collawn J, et al. Negative regulation of NADPH oxidase 4 by hydrogen peroxide-inducible clone 5 (Hic-5) protein. J Biol Chem. 2014;289:18270-8 pubmed 出版商
Fehrholz M, Speer C, Kunzmann S. Caffeine and rolipram affect Smad signalling and TGF-?1 stimulated CTGF and transgelin expression in lung epithelial cells. PLoS ONE. 2014;9:e97357 pubmed 出版商
Solomon J, Heitzer M, Liu T, Beumer J, Parise R, Normolle D, et al. VDR activity is differentially affected by Hic-5 in prostate cancer and stromal cells. Mol Cancer Res. 2014;12:1166-80 pubmed 出版商
Kirkegaard T, Yde C, Kveiborg M, Lykkesfeldt A. The broad-spectrum metalloproteinase inhibitor BB-94 inhibits growth, HER3 and Erk activation in fulvestrant-resistant breast cancer cell lines. Int J Oncol. 2014;45:393-400 pubmed 出版商
Jakobsen R, Østrup E, Zhang X, Mikkelsen T, Brinchmann J. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling. PLoS ONE. 2014;9:e96615 pubmed 出版商
Kofler D, Marson A, Dominguez Villar M, Xiao S, Kuchroo V, Hafler D. Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. J Clin Invest. 2014;124:2513-22 pubmed 出版商
Göbel K, Schuhmann M, Pankratz S, Stegner D, Herrmann A, Braun A, et al. Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis. Eur J Immunol. 2014;44:2295-305 pubmed 出版商
Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, et al. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE. 2014;9:e96695 pubmed 出版商
Luo F, Zhuang Y, Sides M, Sanchez C, Shan B, White E, et al. Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo. Respir Res. 2014;15:51 pubmed 出版商
Li H, Fitchett C, Kozdon K, Jayaram H, Rose G, Bailly M, et al. Independent adipogenic and contractile properties of fibroblasts in Graves' orbitopathy: an in vitro model for the evaluation of treatments. PLoS ONE. 2014;9:e95586 pubmed 出版商
Kumawat K, Menzen M, Slegtenhorst R, Halayko A, Schmidt M, Gosens R. TGF-?-activated kinase 1 (TAK1) signaling regulates TGF-?-induced WNT-5A expression in airway smooth muscle cells via Sp1 and ?-catenin. PLoS ONE. 2014;9:e94801 pubmed 出版商
Tulley S, Chen W. Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-? signaling. J Biol Chem. 2014;289:15280-96 pubmed 出版商
Villegas V, Rahman M, Fernández Barrena M, Diao Y, Liapi E, Sonkoly E, et al. Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1. Mol Oncol. 2014;8:912-26 pubmed 出版商
Wei D, Chiang V, Fyne E, Balakrishnan M, Barnes T, Graupe M, et al. Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing. PLoS Pathog. 2014;10:e1004071 pubmed 出版商
Shi X, DiRenzo D, Guo L, Franco S, Wang B, Seedial S, et al. TGF-?/Smad3 stimulates stem cell/developmental gene expression and vascular smooth muscle cell de-differentiation. PLoS ONE. 2014;9:e93995 pubmed 出版商
Yu Y, Yiang G, Chou P, Tseng H, Wu T, Hung Y, et al. Dual role of acetaminophen in promoting hepatoma cell apoptosis and kidney fibroblast proliferation. Mol Med Rep. 2014;9:2077-84 pubmed 出版商
Miller C, Haas U, DIAZ R, Leeper N, Kundu R, Patlolla B, et al. Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. PLoS Genet. 2014;10:e1004263 pubmed 出版商
Aschner Y, Khalifah A, Briones N, Yamashita C, Dolgonos L, Young S, et al. Protein tyrosine phosphatase ? mediates profibrotic signaling in lung fibroblasts through TGF-? responsiveness. Am J Pathol. 2014;184:1489-502 pubmed 出版商
Jeon K, Kulkarni A, Woeller C, Phipps R, Sime P, Hindman H, et al. Inhibitory effects of PPAR? ligands on TGF-?1-induced corneal myofibroblast transformation. Am J Pathol. 2014;184:1429-45 pubmed 出版商
Xu S, Zhu J, Wu Z. Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-? and induce Tregs development via TGF-?. PLoS ONE. 2014;9:e91709 pubmed 出版商
Olderøy M, Lilledahl M, Beckwith M, Melvik J, Reinholt F, Sikorski P, et al. Biochemical and structural characterization of neocartilage formed by mesenchymal stem cells in alginate hydrogels. PLoS ONE. 2014;9:e91662 pubmed 出版商
Overstreet J, Samarakoon R, Meldrum K, Higgins P. Redox control of p53 in the transcriptional regulation of TGF-?1 target genes through SMAD cooperativity. Cell Signal. 2014;26:1427-36 pubmed 出版商
Kudo Saito C, Yura M, Yamamoto R, Kawakami Y. Induction of immunoregulatory CD271+ cells by metastatic tumor cells that express human endogenous retrovirus H. Cancer Res. 2014;74:1361-70 pubmed 出版商
Ifkovits J, Addis R, Epstein J, Gearhart J. Inhibition of TGF? signaling increases direct conversion of fibroblasts to induced cardiomyocytes. PLoS ONE. 2014;9:e89678 pubmed 出版商
Gao X, Cao Y, Staloch D, Gonzales M, Aronson J, Chao C, et al. Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS ONE. 2014;9:e89114 pubmed 出版商
Mael Ainin M, Abed A, Conway S, Dussaule J, Chatziantoniou C. Inhibition of periostin expression protects against the development of renal inflammation and fibrosis. J Am Soc Nephrol. 2014;25:1724-36 pubmed 出版商
Liu R, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, et al. JAK/STAT3 signaling is required for TGF-?-induced epithelial-mesenchymal transition in lung cancer cells. Int J Oncol. 2014;44:1643-51 pubmed 出版商
Suresh Babu S, Valdez Y, Xu A, O Byrne A, Calvo F, Lei V, et al. TGF?-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells. BMC Cancer. 2014;14:113 pubmed 出版商
Diepenbruck M, Waldmeier L, Ivanek R, Berninger P, Arnold P, van Nimwegen E, et al. Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition. J Cell Sci. 2014;127:1523-36 pubmed 出版商
Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, et al. The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation. Eur J Immunol. 2014;44:1330-40 pubmed 出版商
Italiani P, Mazza E, Lucchesi D, Cifola I, Gemelli C, Grande A, et al. Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro. PLoS ONE. 2014;9:e87680 pubmed 出版商
Oliveira W, Ribeiro L, Schrieffer A, Machado P, Carvalho E, Bacellar O. The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of human tegumentary leishmaniasis. Cytokine. 2014;66:127-32 pubmed 出版商
Ratnayake M, Plöger F, Santibanez Koref M, Loughlin J. Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE. 2014;9:e86590 pubmed 出版商
Wang X, Gui L, Zhang Y, Zhang J, Shi J, Xu G. Cystatin B is a progression marker of human epithelial ovarian tumors mediated by the TGF-β signaling pathway. Int J Oncol. 2014;44:1099-106 pubmed 出版商
Miller M, Petty C, Tompkins M, Fogle J. CD4+CD25+ T regulatory cells activated during feline immunodeficiency virus infection convert T helper cells into functional suppressors through a membrane-bound TGF? / GARP-mediated mechanism. Virol J. 2014;11:7 pubmed 出版商
Chen X, Yang Y, Zhou Q, Weiss J, Howard O, McPherson J, et al. Effective chemoimmunotherapy with anti-TGF? antibody and cyclophosphamide in a mouse model of breast cancer. PLoS ONE. 2014;9:e85398 pubmed 出版商
Rozycki M, Lodyga M, Lam J, Miranda M, Fatyol K, Speight P, et al. The fate of the primary cilium during myofibroblast transition. Mol Biol Cell. 2014;25:643-57 pubmed 出版商
Chen C, Akiyama K, Yamaza T, You Y, Xu X, Li B, et al. Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. EMBO Mol Med. 2014;6:322-34 pubmed 出版商
Kim D, Lee M, Yoo K, Lee T, Kim H, Jang I, et al. Gene expression profiles of human adipose tissue-derived mesenchymal stem cells are modified by cell culture density. PLoS ONE. 2014;9:e83363 pubmed 出版商
Hou S, Landego I, Jayachandran N, Miller A, Gibson I, Ambrose C, et al. Follicular dendritic cell secreted protein FDC-SP controls IgA production. Mucosal Immunol. 2014;7:948-57 pubmed 出版商
Park S, Deering R, Lu Y, Tivnan P, Lianoglou S, Al Shahrour F, et al. Musashi-2 controls cell fate, lineage bias, and TGF-? signaling in HSCs. J Exp Med. 2014;211:71-87 pubmed 出版商
Axpe E, López Euba T, Castellanos Rubio A, Merida D, Garcia J, Plaza Izurieta L, et al. Detection of atomic scale changes in the free volume void size of three-dimensional colorectal cancer cell culture using positron annihilation lifetime spectroscopy. PLoS ONE. 2014;9:e83838 pubmed 出版商
Leung L, Radulovich N, Zhu C, Wang D, To C, Ibrahimov E, et al. Loss of canonical Smad4 signaling promotes KRAS driven malignant transformation of human pancreatic duct epithelial cells and metastasis. PLoS ONE. 2013;8:e84366 pubmed 出版商
Komatsu N, Okamoto K, Sawa S, Nakashima T, Oh Hora M, Kodama T, et al. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis. Nat Med. 2014;20:62-8 pubmed 出版商
Tammaro A, Stroo I, Rampanelli E, Blank F, Butter L, Claessen N, et al. Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy. PLoS ONE. 2013;8:e82498 pubmed 出版商
Serrano I, McDonald P, Lock F, Muller W, Dedhar S. Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nat Commun. 2013;4:2976 pubmed 出版商
Gallo E, Loch D, Habashi J, Calderon J, Chen Y, Bedja D, et al. Angiotensin II-dependent TGF-? signaling contributes to Loeys-Dietz syndrome vascular pathogenesis. J Clin Invest. 2014;124:448-60 pubmed 出版商
Schwartze J, Becker S, Sakkas E, Wujak Ł, Niess G, Usemann J, et al. Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-? signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts. J Biol Chem. 2014;289:3262-75 pubmed 出版商
O Connor J, Gomez E. Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling. PLoS ONE. 2013;8:e83188 pubmed 出版商
Matsuhashi S, Hamajima H, Xia J, Zhang H, Mizuta T, Anzai K, et al. Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells. Cell Signal. 2014;26:603-10 pubmed 出版商
Karki S, Surolia R, Hock T, Guroji P, Zolak J, Duggal R, et al. Wilms' tumor 1 (Wt1) regulates pleural mesothelial cell plasticity and transition into myofibroblasts in idiopathic pulmonary fibrosis. FASEB J. 2014;28:1122-31 pubmed 出版商
Rojo J, Ojeda G, Acosta Y, Montes Casado M, Criado G, Portoles P. Characteristics of TCR/CD3 complex CD3{varepsilon} chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo. J Leukoc Biol. 2014;95:441-50 pubmed 出版商
Baldwin A, Cain S, Lennon R, GODWIN A, Merry C, Kielty C. Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. J Cell Sci. 2014;127:158-71 pubmed 出版商
Yasmin N, Bauer T, Modak M, Wagner K, Schuster C, Köffel R, et al. Identification of bone morphogenetic protein 7 (BMP7) as an instructive factor for human epidermal Langerhans cell differentiation. J Exp Med. 2013;210:2597-610 pubmed 出版商
Brady K, Dickinson S, Guillot P, Polak J, Blom A, Kafienah W, et al. Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis. Stem Cells Dev. 2014;23:541-54 pubmed 出版商
Long J, Badal S, Wang Y, Chang B, Rodriguez A, Danesh F. MicroRNA-22 is a master regulator of bone morphogenetic protein-7/6 homeostasis in the kidney. J Biol Chem. 2013;288:36202-14 pubmed 出版商
Acuña M, Pessina P, Olguin H, Cabrera D, Vio C, Bader M, et al. Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-? signalling. Hum Mol Genet. 2014;23:1237-49 pubmed 出版商
Yao G, Liang M, Liang N, Yin M, Lü M, Lian J, et al. MicroRNA-224 is involved in the regulation of mouse cumulus expansion by targeting Ptx3. Mol Cell Endocrinol. 2014;382:244-253 pubmed 出版商
Wang X, Hu Y, Charpentier T, Lamarre A, Qi S, Wu J, et al. TNF-like ligand 1A (TL1A) gene knockout leads to ameliorated collagen-induced arthritis in mice: implication of TL1A in humoral immune responses. J Immunol. 2013;191:5420-9 pubmed 出版商
Sun H, Sun C, Xiao W. Expression regulation of co-inhibitory molecules on human natural killer cells in response to cytokine stimulations. Cytokine. 2014;65:33-41 pubmed 出版商
Zheng J, Wu C, Lin Z, Guo Y, Shi L, Dong P, et al. Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis. FEBS J. 2014;281:88-103 pubmed 出版商
Midgley A, Bowen T, Phillips A, Steadman R. MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts. Aging Cell. 2014;13:235-44 pubmed 出版商
Keune W, Sims A, Jones D, Bultsma Y, Lynch J, Jirstrom K, et al. Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression. Cancer Res. 2013;73:6913-25 pubmed 出版商
Nasarre P, Gemmill R, Potiron V, Roche J, Lu X, Baron A, et al. Neuropilin-2 Is upregulated in lung cancer cells during TGF-?1-induced epithelial-mesenchymal transition. Cancer Res. 2013;73:7111-21 pubmed 出版商
Cheng J, Chang H, Leung P. Transforming growth factor-?1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein. J Biol Chem. 2013;288:33181-92 pubmed 出版商
Hung C, Rohani M, Lee S, Chen P, Schnapp L. Role of IGF-1 pathway in lung fibroblast activation. Respir Res. 2013;14:102 pubmed 出版商
Ramdas V, McBride M, Denby L, Baker A. Canonical transforming growth factor-? signaling regulates disintegrin metalloprotease expression in experimental renal fibrosis via miR-29. Am J Pathol. 2013;183:1885-1896 pubmed 出版商
Lin Y, Zhang B, Liang H, Lu Y, Ai X, Zhang B, et al. JNK inhibitor SP600125 enhances TGF-?-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner. Mol Med Rep. 2013;8:1623-9 pubmed 出版商
Xu Z, Zhang Q, Li H. Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-?1 and platelet-derived growth factor BB. Mol Med Rep. 2013;8:1715-21 pubmed 出版商
Zhou Q, Hu Y, Howard O, Oppenheim J, Chen X. In vitro generated Th17 cells support the expansion and phenotypic stability of CD4(+)Foxp3(+) regulatory T cells in vivo. Cytokine. 2014;65:56-64 pubmed 出版商
Ueda J, Matsuda Y, Yamahatsu K, Uchida E, Naito Z, Korc M, et al. Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases. Oncogene. 2014;33:4485-95 pubmed 出版商
Kinashi H, Ito Y, Mizuno M, Suzuki Y, Terabayashi T, Nagura F, et al. TGF-?1 promotes lymphangiogenesis during peritoneal fibrosis. J Am Soc Nephrol. 2013;24:1627-42 pubmed 出版商
Wu Y, Chang T, Huang Y, Huang H, Chou C. COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer. Oncogene. 2014;33:3432-40 pubmed 出版商
Qu X, Shen L, Zheng Y, Cui Y, Feng Z, Liu F, et al. A signal transduction pathway from TGF-?1 to SKP2 via Akt1 and c-Myc and its correlation with progression in human melanoma. J Invest Dermatol. 2014;134:159-167 pubmed 出版商
Park J, Kato M, Yuan H, Castro N, Lanting L, Wang M, et al. FOG2 protein down-regulation by transforming growth factor-?1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy. J Biol Chem. 2013;288:22469-80 pubmed 出版商
Hanieh H, Alzahrani A. MicroRNA-132 suppresses autoimmune encephalomyelitis by inducing cholinergic anti-inflammation: a new Ahr-based exploration. Eur J Immunol. 2013;43:2771-82 pubmed 出版商
Loureiro J, Sandoval P, del Peso G, Gonzalez Mateo G, Fernandez Millara V, Santamaria B, et al. Tamoxifen ameliorates peritoneal membrane damage by blocking mesothelial to mesenchymal transition in peritoneal dialysis. PLoS ONE. 2013;8:e61165 pubmed 出版商
Yanaba K, Kamata M, Ishiura N, Shibata S, Asano Y, Tada Y, et al. Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. J Leukoc Biol. 2013;94:563-73 pubmed 出版商
Ammann J, Cooke A, Trowsdale J. Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes. J Immunol. 2013;190:5030-6 pubmed 出版商
Stephens G, Wang Q, Swerdlow B, Bhat G, Kolbeck R, Fung M. Kynurenine 3-monooxygenase mediates inhibition of Th17 differentiation via catabolism of endogenous aryl hydrocarbon receptor ligands. Eur J Immunol. 2013;43:1727-34 pubmed 出版商
Liu M, Wang H, Wang Z, Zhang Y, Chen Y, Zhu F, et al. TGF-?1 regulation of estrogen production in mature rat Leydig cells. PLoS ONE. 2013;8:e60197 pubmed 出版商
Götz A, Jessberger R. Dendritic cell podosome dynamics does not depend on the F-actin regulator SWAP-70. PLoS ONE. 2013;8:e60642 pubmed 出版商
Geng L, Chaudhuri A, Talmon G, Wisecarver J, Wang J. TGF-Beta suppresses VEGFA-mediated angiogenesis in colon cancer metastasis. PLoS ONE. 2013;8:e59918 pubmed 出版商
Lund T, Kobs A, Kramer A, Nyquist M, Kuroki M, Osborn J, et al. Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression. PLoS ONE. 2013;8:e58945 pubmed 出版商
Wang C, Yi T, Qin L, Maldonado R, von Andrian U, Kulkarni S, et al. Rapamycin-treated human endothelial cells preferentially activate allogeneic regulatory T cells. J Clin Invest. 2013;123:1677-93 pubmed 出版商
Romero D, Kawano Y, Bengoa N, Walker M, Maltry N, Niehrs C, et al. Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-?/Smad signalling. J Cell Sci. 2013;126:1858-67 pubmed 出版商
Gu L, Johno H, Nakajima S, Kato H, Takahashi S, Katoh R, et al. Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential. Lab Invest. 2013;93:450-61 pubmed 出版商
Tannetta D, Dragovic R, Gardiner C, Redman C, Sargent I. Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin. PLoS ONE. 2013;8:e56754 pubmed 出版商
Hojo H, Ohba S, Taniguchi K, Shirai M, Yano F, Saito T, et al. Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium. J Biol Chem. 2013;288:9924-32 pubmed 出版商
Nguyen H, Zhuang Y, Sun L, Kantrow S, Kolls J, You Z, et al. Src-mediated morphology transition of lung cancer cells in three-dimensional organotypic culture. Cancer Cell Int. 2013;13:16 pubmed 出版商
Masani S, Han L, Yu K. Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination. Mol Cell Biol. 2013;33:1468-73 pubmed 出版商
Shinojima N, Hossain A, Takezaki T, Fueyo J, Gumin J, Gao F, et al. TGF-? mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells. Cancer Res. 2013;73:2333-44 pubmed 出版商
Mae S, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda Nishimura N, et al. Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun. 2013;4:1367 pubmed 出版商
Truchetet M, Brembilla N, Montanari E, Lonati P, Raschi E, Zeni S, et al. Interleukin-17A+ cell counts are increased in systemic sclerosis skin and their number is inversely correlated with the extent of skin involvement. Arthritis Rheum. 2013;65:1347-56 pubmed 出版商
Balli D, Ustiyan V, Zhang Y, Wang I, Masino A, Ren X, et al. Foxm1 transcription factor is required for lung fibrosis and epithelial-to-mesenchymal transition. EMBO J. 2013;32:231-44 pubmed 出版商
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet. 2013;45:34-42 pubmed 出版商
Wu C, Chiang W, Lai C, Chang F, Chen Y, Chou Y, et al. Transforming growth factor ?-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis. Am J Pathol. 2013;182:118-31 pubmed 出版商
Sohni A, Mulas F, Ferrazzi F, Luttun A, Bellazzi R, Huylebroeck D, et al. TGF?1-induced Baf60c regulates both smooth muscle cell commitment and quiescence. PLoS ONE. 2012;7:e47629 pubmed 出版商
Abushahba W, Olabisi O, Jeong B, Boregowda R, Wen Y, Liu F, et al. Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma. PLoS ONE. 2012;7:e47312 pubmed 出版商
Bauer T, Zagorska A, Jurkin J, Yasmin N, Köffel R, Richter S, et al. Identification of Axl as a downstream effector of TGF-?1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med. 2012;209:2033-47 pubmed 出版商
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol. 2012;10:e1001395 pubmed 出版商
Huse K, Bakkebø M, Walchli S, Oksvold M, Hilden V, Forfang L, et al. Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma. PLoS ONE. 2012;7:e46117 pubmed 出版商
Krishnan A, Li X, Kao W, Viker K, Butters K, Masuoka H, et al. Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis. Lab Invest. 2012;92:1712-25 pubmed 出版商
Kudo Y, Iizuka S, Yoshida M, Tsunematsu T, Kondo T, Subarnbhesaj A, et al. Matrix metalloproteinase-13 (MMP-13) directly and indirectly promotes tumor angiogenesis. J Biol Chem. 2012;287:38716-28 pubmed 出版商
Cerchia L, Esposito C, Camorani S, Rienzo A, Stasio L, Insabato L, et al. Targeting Axl with an high-affinity inhibitory aptamer. Mol Ther. 2012;20:2291-303 pubmed 出版商
Li J, Mo H, Xiong G, Zhang L, He J, Huang Z, et al. Tumor microenvironment macrophage inhibitory factor directs the accumulation of interleukin-17-producing tumor-infiltrating lymphocytes and predicts favorable survival in nasopharyngeal carcinoma patients. J Biol Chem. 2012;287:35484-95 pubmed 出版商
Flanagan K, FITZGERALD K, Baker J, Regnstrom K, Gardai S, Bard F, et al. Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS. PLoS ONE. 2012;7:e40443 pubmed 出版商
Bruce D, MacArtney T, Yong W, Shou W, Sapkota G. Protein phosphatase 5 modulates SMAD3 function in the transforming growth factor-? pathway. Cell Signal. 2012;24:1999-2006 pubmed 出版商
Purwar R, Schlapbach C, Xiao S, Kang H, Elyaman W, Jiang X, et al. Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med. 2012;18:1248-53 pubmed 出版商
Nam D, Mau E, Wang Y, Wright D, Silkstone D, Whetstone H, et al. T-lymphocytes enable osteoblast maturation via IL-17F during the early phase of fracture repair. PLoS ONE. 2012;7:e40044 pubmed 出版商
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed 出版商
Ng F, Toh T, Ting E, Koh G, Sandanaraj E, Phong M, et al. Progenitor-like traits contribute to patient survival and prognosis in oligodendroglial tumors. Clin Cancer Res. 2012;18:4122-35 pubmed
Grubisha M, Cifuentes M, Hammes S, DeFranco D. A local paracrine and endocrine network involving TGF?, Cox-2, ROS, and estrogen receptor ? influences reactive stromal cell regulation of prostate cancer cell motility. Mol Endocrinol. 2012;26:940-54 pubmed 出版商
Pignatelli J, Tumbarello D, Schmidt R, Turner C. Hic-5 promotes invadopodia formation and invasion during TGF-?-induced epithelial-mesenchymal transition. J Cell Biol. 2012;197:421-37 pubmed 出版商
Casey K, Fraser K, Schenkel J, Moran A, Abt M, Beura L, et al. Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues. J Immunol. 2012;188:4866-75 pubmed 出版商
Liu Y, Yin J, Abou Kheir W, Hynes P, Casey O, Fang L, et al. MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms. Oncogene. 2013;32:296-306 pubmed 出版商
Dupuy S, Lambert M, Zucman D, Choukem S, Tognarelli S, Pagès C, et al. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog. 2012;8:e1002486 pubmed 出版商
Radulovic K, Manta C, Rossini V, Holzmann K, Kestler H, Wegenka U, et al. CD69 regulates type I IFN-induced tolerogenic signals to mucosal CD4 T cells that attenuate their colitogenic potential. J Immunol. 2012;188:2001-13 pubmed 出版商
Jin W, Qi S, Luo H. The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and function. BMC Immunol. 2011;12:68 pubmed 出版商
Yamazaki S, Ema H, Karlsson G, Yamaguchi T, Miyoshi H, Shioda S, et al. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell. 2011;147:1146-58 pubmed 出版商
Duchez S, Pascal V, Cogne N, Jayat Vignoles C, Julien R, Cogne M. Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation. Eur J Immunol. 2011;41:3632-44 pubmed 出版商
Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu D, Yanaba M, et al. Host-derived MCP-1 and MIP-1? regulate protective anti-tumor immunity to localized and metastatic B16 melanoma. Am J Pathol. 2012;180:365-74 pubmed 出版商
Mottershead D, Ritter L, Gilchrist R. Signalling pathways mediating specific synergistic interactions between GDF9 and BMP15. Mol Hum Reprod. 2012;18:121-8 pubmed 出版商
Yilmaz M, Maass D, Tiwari N, Waldmeier L, Schmidt P, Lehembre F, et al. Transcription factor Dlx2 protects from TGF?-induced cell-cycle arrest and apoptosis. EMBO J. 2011;30:4489-99 pubmed 出版商
Nakahama T, Kimura A, Nguyen N, Chinen I, Hanieh H, Nohara K, et al. Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis. Proc Natl Acad Sci U S A. 2011;108:14222-7 pubmed 出版商
Liu F, Chen H, Huang X, Chung A, Zhou L, Fu P, et al. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes. Diabetologia. 2011;54:2713-23 pubmed 出版商
Eisenwort G, Jurkin J, Yasmin N, Bauer T, Gesslbauer B, Strobl H. Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-?1-dependent human epidermal Langerhans cells. J Invest Dermatol. 2011;131:2049-57 pubmed 出版商
Davis Dusenbery B, Chan M, Reno K, Weisman A, Layne M, Lagna G, et al. down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4. J Biol Chem. 2011;286:28097-110 pubmed 出版商
Zi Z, Feng Z, Chapnick D, Dahl M, Deng D, Klipp E, et al. Quantitative analysis of transient and sustained transforming growth factor-? signaling dynamics. Mol Syst Biol. 2011;7:492 pubmed 出版商
Hoffman A, Paxson J, Mazan M, Davis A, Tyagi S, Murthy S, et al. Lung-derived mesenchymal stromal cell post-transplantation survival, persistence, paracrine expression, and repair of elastase-injured lung. Stem Cells Dev. 2011;20:1779-92 pubmed 出版商
Zheng L, Foley K, Huang L, Leubner A, Mo G, Olino K, et al. Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer. PLoS ONE. 2011;6:e19390 pubmed 出版商
El Behi M, Ciric B, Dai H, Yan Y, Cullimore M, Safavi F, et al. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nat Immunol. 2011;12:568-75 pubmed 出版商
Kashiwada M, CASSEL S, COLGAN J, Rothman P. NFIL3/E4BP4 controls type 2 T helper cell cytokine expression. EMBO J. 2011;30:2071-82 pubmed 出版商
Boswell S, Sharif S, Alisa A, Pereira S, Williams R, Behboudi S. Induction of latency-associated peptide (transforming growth factor-?(1)) expression on CD4+ T cells reduces Toll-like receptor 4 ligand-induced tumour necrosis factor-? production in a transforming growth factor-?-dependent manner. Immunology. 2011;133:278-87 pubmed 出版商
Gregory P, Bracken C, Smith E, Bert A, Wright J, Roslan S, et al. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition. Mol Biol Cell. 2011;22:1686-98 pubmed 出版商
Sierra Filardi E, Puig Kröger A, Blanco F, Nieto C, Bragado R, Palomero M, et al. Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers. Blood. 2011;117:5092-101 pubmed 出版商
Ma Y, Aymeric L, Locher C, Mattarollo S, Delahaye N, Pereira P, et al. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med. 2011;208:491-503 pubmed 出版商
Henriksson M, Edin S, Dahlin A, Oldenborg P, Oberg A, Van Guelpen B, et al. Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion. Am J Pathol. 2011;178:1387-94 pubmed 出版商
Depaolo R, Abadie V, Tang F, Fehlner Peach H, Hall J, Wang W, et al. Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature. 2011;471:220-4 pubmed 出版商
Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, et al. Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. Am J Pathol. 2011;178:572-9 pubmed 出版商
Elkabets M, Gifford A, Scheel C, Nilsson B, Reinhardt F, Bray M, et al. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J Clin Invest. 2011;121:784-99 pubmed 出版商
Bohr W, Kupper M, Hoffmann K, Weiskirchen R. Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein. PLoS ONE. 2010;5:e16000 pubmed 出版商
Krueger C, Hoffmann F. Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. PLoS ONE. 2010;5:e15511 pubmed 出版商
Ley C, Svala E, Nilton A, Lindahl A, Eloranta M, Ekman S, et al. Effects of high mobility group box protein-1, interleukin-1?, and interleukin-6 on cartilage matrix metabolism in three-dimensional equine chondrocyte cultures. Connect Tissue Res. 2011;52:290-300 pubmed 出版商
Bourne G, Grainger D. Development and characterisation of an assay for furin activity. J Immunol Methods. 2011;364:101-8 pubmed 出版商
Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, et al. HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies. J Virol. 2011;85:1077-85 pubmed 出版商
Gibbings S, Elkins N, Fitzgerald H, Tiao J, Weyman M, Shibao G, et al. Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}. J Biol Chem. 2011;286:961-75 pubmed 出版商
Tan C, Aziz M, Lovaas J, Vistica B, Shi G, Wawrousek E, et al. Antigen-specific Th9 cells exhibit uniqueness in their kinetics of cytokine production and short retention at the inflammatory site. J Immunol. 2010;185:6795-801 pubmed 出版商
Boenisch O, D Addio F, Watanabe T, Elyaman W, Magee C, Yeung M, et al. TIM-3: a novel regulatory molecule of alloimmune activation. J Immunol. 2010;185:5806-19 pubmed 出版商
Maupin K, Sinha A, Eugster E, Miller J, Ross J, Paulino V, et al. Glycogene expression alterations associated with pancreatic cancer epithelial-mesenchymal transition in complementary model systems. PLoS ONE. 2010;5:e13002 pubmed 出版商
Jones G, Stumhofer J, Foster T, Twohig J, Hertzog P, Topley N, et al. Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J. 2011;25:409-19 pubmed 出版商
Suzuki K, Maruya M, Kawamoto S, Sitnik K, Kitamura H, Agace W, et al. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut. Immunity. 2010;33:71-83 pubmed 出版商
Chen G, Hardy K, Bunting K, Daley S, Ma L, Shannon M. Regulation of the IL-21 gene by the NF-?B transcription factor c-Rel. J Immunol. 2010;185:2350-9 pubmed 出版商
Yoshizaki A, Yanaba K, Iwata Y, Komura K, Ogawa A, Akiyama Y, et al. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model. J Immunol. 2010;185:2502-15 pubmed 出版商
Chang H, Sehra S, Goswami R, Yao W, Yu Q, Stritesky G, et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat Immunol. 2010;11:527-34 pubmed 出版商
Rai D, Kim S, McKeller M, Dahia P, Aguiar R. Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. Proc Natl Acad Sci U S A. 2010;107:3111-6 pubmed 出版商
Morizane S, Yamasaki K, Kabigting F, Gallo R. Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J Invest Dermatol. 2010;130:1297-306 pubmed 出版商
Jones G, McLoughlin R, Hammond V, Parker C, Williams J, Malhotra R, et al. Loss of CD4+ T cell IL-6R expression during inflammation underlines a role for IL-6 trans signaling in the local maintenance of Th17 cells. J Immunol. 2010;184:2130-9 pubmed 出版商
Roux J, Carles M, Koh H, Goolaerts A, Ganter M, Chesebro B, et al. Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism. J Biol Chem. 2010;285:4278-90 pubmed 出版商
Miyake T, Alli N, McDermott J. Nuclear function of Smad7 promotes myogenesis. Mol Cell Biol. 2010;30:722-35 pubmed 出版商
Lee W, Kang S, Choi J, Lee S, Shah K, Eynon E, et al. Regulating human Th17 cells via differential expression of IL-1 receptor. Blood. 2010;115:530-40 pubmed 出版商
Seyerl M, Kirchberger S, Majdic O, Seipelt J, Jindra C, Schrauf C, et al. Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. Eur J Immunol. 2010;40:321-9 pubmed 出版商
Moransard M, Sawitzky M, Fontana A, Suter T. Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis. Glia. 2010;58:559-71 pubmed 出版商
Stockis J, Colau D, Coulie P, Lucas S. Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg. Eur J Immunol. 2009;39:3315-22 pubmed 出版商
Duraisingham S, Hornig J, Gotch F, Patterson S. TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses. J Immunol. 2009;183:2242-51 pubmed 出版商
Veraldi K, Gibson B, Yasuoka H, MYERBURG M, Kelly E, Balzar S, et al. Role of insulin-like growth factor binding protein-3 in allergic airway remodeling. Am J Respir Crit Care Med. 2009;180:611-7 pubmed 出版商
Margulis A, Nocka K, Brennan A, Deng B, Fleming M, Goldman S, et al. Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases. J Immunol. 2009;183:1739-50 pubmed 出版商
Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat Immunol. 2009;10:857-63 pubmed 出版商
Pedroja B, Kang L, Imas A, Carmeliet P, Bernstein A. Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling. J Biol Chem. 2009;284:20708-17 pubmed 出版商
Vitsky A, Waire J, Pawliuk R, Bond A, Matthews D, Lacasse E, et al. Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues. Am J Pathol. 2009;174:2137-49 pubmed 出版商
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, et al. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int J Cancer. 2009;125:367-73 pubmed 出版商
Aliahmadi E, Gramlich R, Grützkau A, Hitzler M, Krüger M, Baumgrass R, et al. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur J Immunol. 2009;39:1221-30 pubmed 出版商
Shafer S, Towler D. Transcriptional regulation of SM22alpha by Wnt3a: convergence with TGFbeta(1)/Smad signaling at a novel regulatory element. J Mol Cell Cardiol. 2009;46:621-35 pubmed 出版商
Dai Z, Turtle C, Booth G, Riddell S, Gooley T, Stevens A, et al. Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J Exp Med. 2009;206:793-805 pubmed 出版商
Boniface K, Bak Jensen K, Li Y, Blumenschein W, McGeachy M, McClanahan T, et al. Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J Exp Med. 2009;206:535-48 pubmed 出版商
Amiable N, Tat S, Lajeunesse D, Duval N, Pelletier J, Martel Pelletier J, et al. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone. 2009;44:1143-50 pubmed 出版商
Eid R, Rao D, Zhou J, Lo S, Ranjbaran H, Gallo A, et al. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation. 2009;119:1424-32 pubmed 出版商
van Steensel L, Paridaens D, Schrijver B, Dingjan G, van Daele P, van Hagen P, et al. Imatinib mesylate and AMN107 inhibit PDGF-signaling in orbital fibroblasts: a potential treatment for Graves' ophthalmopathy. Invest Ophthalmol Vis Sci. 2009;50:3091-8 pubmed 出版商
Sehrawat S, Suryawanshi A, Hirashima M, Rouse B. Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators. J Immunol. 2009;182:3191-201 pubmed 出版商
Bhowmick S, Mazumdar T, Ali N. Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection. Infect Immun. 2009;77:1514-23 pubmed 出版商
Shi S, Mercer S, Eckert G, Trippel S. Growth factor regulation of growth factors in articular chondrocytes. J Biol Chem. 2009;284:6697-704 pubmed 出版商
Nolan Stevaux O, Lau J, Truitt M, Chu G, Hebrok M, Fernandez Zapico M, et al. GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes Dev. 2009;23:24-36 pubmed 出版商
Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, et al. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J Exp Med. 2009;206:249-58 pubmed 出版商
Han Y, Guo Q, Zhang M, Chen Z, Cao X. CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1. J Immunol. 2009;182:111-20 pubmed
Lamba S, Ravichandran V, Major E. Glial cell type-specific subcellular localization of 14-3-3 zeta: an implication for JCV tropism. Glia. 2009;57:971-7 pubmed 出版商
Kinoshita H, Takai T, Le T, Kamijo S, Wang X, Ushio H, et al. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J Allergy Clin Immunol. 2009;123:179-86 pubmed 出版商
Sugiura H, Ichikawa T, Koarai A, Yanagisawa S, Minakata Y, Matsunaga K, et al. Activation of Toll-like receptor 3 augments myofibroblast differentiation. Am J Respir Cell Mol Biol. 2009;40:654-62 pubmed 出版商
Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, et al. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs. Arthritis Rheum. 2008;58:3510-9 pubmed 出版商
Herman S, Müller R, Kronke G, Zwerina J, Redlich K, Hueber A, et al. Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis. Arthritis Rheum. 2008;58:3041-50 pubmed 出版商
Tsoporis J, Izhar S, Parker T. Expression of S100A6 in cardiac myocytes limits apoptosis induced by tumor necrosis factor-alpha. J Biol Chem. 2008;283:30174-83 pubmed 出版商
Pen A, Moreno M, Durocher Y, Deb Rinker P, Stanimirovic D. Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling. Oncogene. 2008;27:6834-44 pubmed 出版商
Aoudjehane L, Pissaia A, Scatton O, Podevin P, Massault P, Chouzenoux S, et al. Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway. Lab Invest. 2008;88:973-85 pubmed 出版商
Shinohara M, Kim J, Garcia V, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008;29:68-78 pubmed 出版商
Barbaroux J, Beleut M, Brisken C, Mueller C, Groves R. Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation. J Immunol. 2008;181:1103-8 pubmed
Kanswal S, Katsenelson N, Selvapandiyan A, Bram R, Akkoyunlu M. Deficient TACI expression on B lymphocytes of newborn mice leads to defective Ig secretion in response to BAFF or APRIL. J Immunol. 2008;181:976-90 pubmed
Walsh M, Ampasala D, Hatfield J, Vander Heide R, Suer S, Rishi A, et al. Transforming growth factor-beta stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms. Am J Pathol. 2008;173:385-99 pubmed 出版商
Carlson M, Hsu M, Conboy I. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature. 2008;454:528-32 pubmed 出版商
Cox C, Shi G, Yin H, Vistica B, Wawrousek E, Chan C, et al. Both Th1 and Th17 are immunopathogenic but differ in other key biological activities. J Immunol. 2008;180:7414-22 pubmed
Ke Y, Jiang G, Sun D, Kaplan H, Shao H. Ocular regulatory T cells distinguish monophasic from recurrent autoimmune uveitis. Invest Ophthalmol Vis Sci. 2008;49:3999-4007 pubmed 出版商
Fineschi S, Bongiovanni M, Donati Y, Djaafar S, Naso F, Goffin L, et al. In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis. Am J Respir Cell Mol Biol. 2008;39:458-65 pubmed 出版商
Marsh D, Dickinson S, Neill G, Marshall J, Hart I, Thomas G. alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. Cancer Res. 2008;68:3295-303 pubmed 出版商
Kuchtey J, Kallberg M, Gelatt K, Rinkoski T, Komaromy A, Kuchtey R. Angiopoietin-like 7 secretion is induced by glaucoma stimuli and its concentration is elevated in glaucomatous aqueous humor. Invest Ophthalmol Vis Sci. 2008;49:3438-48 pubmed 出版商
Kato A, Peters A, Suh L, Carter R, Harris K, Chandra R, et al. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol. 2008;121:1385-92, 1392.e1-2 pubmed 出版商
Haydont V, Riser B, Aigueperse J, Vozenin Brotons M. Specific signals involved in the long-term maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF-beta1. Am J Physiol Cell Physiol. 2008;294:C1332-41 pubmed 出版商
Guo B, Chang E, Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J Clin Invest. 2008;118:1680-90 pubmed 出版商
Sheng M, Wergedal J, Mohan S, Lau K. Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity. FEBS Lett. 2008;582:1451-8 pubmed 出版商
Martinez Alvernia E, Rudnick J, Mankarious L. Transforming growth factor beta3 increases chondrocyte proliferation and decreases apoptosis in murine cricoid cartilage in vitro. Otolaryngol Head Neck Surg. 2008;138:435-40 pubmed 出版商
Muranski P, Boni A, Antony P, Cassard L, Irvine K, Kaiser A, et al. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood. 2008;112:362-73 pubmed 出版商
Pittet P, Lee K, Kulik A, Meister J, Hinz B. Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds. J Cell Sci. 2008;121:877-86 pubmed 出版商
Van Aarsen L, Leone D, Ho S, Dolinski B, McCoon P, Lepage D, et al. Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism. Cancer Res. 2008;68:561-70 pubmed 出版商
Oh J, Kim M, Shin M, Lee H, Ko J, Wee W, et al. The anti-inflammatory and anti-angiogenic role of mesenchymal stem cells in corneal wound healing following chemical injury. Stem Cells. 2008;26:1047-55 pubmed 出版商
Anderson B, Christiansen S, McLoon L. Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the treatment of strabismus. Invest Ophthalmol Vis Sci. 2008;49:221-9 pubmed 出版商
Link D, van den Dolder J, van den Beucken J, Wolke J, Mikos A, Jansen J. Bone response and mechanical strength of rabbit femoral defects filled with injectable CaP cements containing TGF-beta 1 loaded gelatin microparticles. Biomaterials. 2008;29:675-82 pubmed
McGeachy M, Bak Jensen K, Chen Y, Tato C, Blumenschein W, McClanahan T, et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat Immunol. 2007;8:1390-7 pubmed
Korff T, Aufgebauer K, Hecker M. Cyclic stretch controls the expression of CD40 in endothelial cells by changing their transforming growth factor-beta1 response. Circulation. 2007;116:2288-97 pubmed
Bujak M, Ren G, Kweon H, Dobaczewski M, Reddy A, Taffet G, et al. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation. 2007;116:2127-38 pubmed
Reed S, Johnson S. Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types. J Cell Physiol. 2008;215:329-36 pubmed
Baker K, Raut P, Jass J. Microsatellite unstable colorectal cancer cell lines with truncating TGFbetaRII mutations remain sensitive to endogenous TGFbeta. J Pathol. 2007;213:257-65 pubmed
Kang S, Lim H, Andrisani O, Broxmeyer H, Kim C. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007;179:3724-33 pubmed
Lamar J, Iyer V, DiPersio C. Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes. J Invest Dermatol. 2008;128:575-86 pubmed
Tanno T, Bhanu N, Oneal P, Goh S, Staker P, Lee Y, et al. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med. 2007;13:1096-101 pubmed
Shintani Y, Maeda M, Chaika N, Johnson K, Wheelock M. Collagen I promotes epithelial-to-mesenchymal transition in lung cancer cells via transforming growth factor-beta signaling. Am J Respir Cell Mol Biol. 2008;38:95-104 pubmed
Kato A, Favoreto S, Avila P, Schleimer R. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J Immunol. 2007;179:1080-7 pubmed
Bogatkevich G, Ludwicka Bradley A, Highland K, Hant F, Nietert P, Singleton C, et al. Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis. Arthritis Rheum. 2007;56:2432-42 pubmed
Toscano M, Bianco G, Ilarregui J, Croci D, Correale J, Hernandez J, et al. Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nat Immunol. 2007;8:825-34 pubmed
Zeisberg M, Yang C, Martino M, Duncan M, Rieder F, Tanjore H, et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem. 2007;282:23337-47 pubmed
Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, et al. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease. J Clin Invest. 2007;117:1951-60 pubmed
Hong K, Belperio J, Keane M, Burdick M, Strieter R. Differentiation of human circulating fibrocytes as mediated by transforming growth factor-beta and peroxisome proliferator-activated receptor gamma. J Biol Chem. 2007;282:22910-20 pubmed
McLennan S, Kelly D, Schache M, Waltham M, Dy V, Langham R, et al. Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?. Kidney Int. 2007;72:481-8 pubmed
Liu S, Tsai J, Shen C, Sher Y, Hsieh C, Yeh Y, et al. Induction of a distinct CD8 Tnc17 subset by transforming growth factor-beta and interleukin-6. J Leukoc Biol. 2007;82:354-60 pubmed
Ao M, Franco O, Park D, Raman D, Williams K, Hayward S. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res. 2007;67:4244-53 pubmed
Ball S, Shuttleworth C, Kielty C. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol. 2007;177:489-500 pubmed
Tacke F, Gabele E, Bataille F, Schwabe R, Hellerbrand C, Klebl F, et al. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells. Dig Dis Sci. 2007;52:3404-15 pubmed
Zakrzewicz A, Kouri F, Nejman B, Kwapiszewska G, Hecker M, Sandu R, et al. The transforming growth factor-beta/Smad2,3 signalling axis is impaired in experimental pulmonary hypertension. Eur Respir J. 2007;29:1094-104 pubmed
Brechter A, Lerner U. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression. Arthritis Rheum. 2007;56:910-23 pubmed
Ashworth T, Roy A. Cutting Edge: TFII-I controls B cell proliferation via regulating NF-kappaB. J Immunol. 2007;178:2631-5 pubmed
Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
Zheng S, Wang J, Wang P, Gray J, Horwitz D. IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. J Immunol. 2007;178:2018-27 pubmed
Ungefroren H, Schniewind B, Groth S, Chen W, Müerköster S, Kalthoff H, et al. Antitumor activity of ALK1 in pancreatic carcinoma cells. Int J Cancer. 2007;120:1641-51 pubmed
Ogawa K, Funaba M, Chen Y, Tsujimoto M. Activin A functions as a Th2 cytokine in the promotion of the alternative activation of macrophages. J Immunol. 2006;177:6787-94 pubmed
Rafei M, Wu J, Annabi B, Lejeune L, Francois M, Galipeau J. A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex. Blood. 2007;109:2234-42 pubmed
Andl C, Fargnoli B, Okawa T, Bowser M, Takaoka M, Nakagawa H, et al. Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo. Cancer Res. 2006;66:9878-85 pubmed
Rose D, Sydlaske A, Agha Babakhani A, Johnson K, Terkeltaub R. Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils. Arthritis Rheum. 2006;54:3363-71 pubmed
Mukhopadhyay A, Chan S, Lim I, Phillips D, Phan T. The role of the activin system in keloid pathogenesis. Am J Physiol Cell Physiol. 2007;292:C1331-8 pubmed
Rosendahl A, Forsberg G. IGF-I and IGFBP-3 augment transforming growth factor-beta actions in human renal carcinoma cells. Kidney Int. 2006;70:1584-90 pubmed
Letterio J, Rudikoff E, Voong N, Bauer S. Transforming growth factor-beta1 sensitivity is altered in Abl-Myc- and Raf-Myc-induced mouse pre-B-cell tumors. Stem Cells. 2006;24:2611-7 pubmed
Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, et al. Multipotent adult progenitor cells from swine bone marrow. Stem Cells. 2006;24:2355-66 pubmed
Yu H, Fang D, Kumar S, Li L, Nguyen T, Acs G, et al. Isolation of a novel population of multipotent adult stem cells from human hair follicles. Am J Pathol. 2006;168:1879-88 pubmed
Li Y, Fan J, Chen M, Li W, Woodley D. Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J Invest Dermatol. 2006;126:2096-105 pubmed
Bettelli E, Carrier Y, Gao W, Korn T, Strom T, Oukka M, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006;441:235-8 pubmed
Maeshima A, Vaughn D, Choi Y, Nigam S. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Dev Biol. 2006;295:473-85 pubmed
Rhodes K, Raivich G, Fawcett J. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience. 2006;140:87-100 pubmed
Wolk K, Witte E, Wallace E, Döcke W, Kunz S, Asadullah K, et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol. 2006;36:1309-23 pubmed
Leng Q, Bentwich Z, Borkow G. Increased TGF-beta, Cbl-b and CTLA-4 levels and immunosuppression in association with chronic immune activation. Int Immunol. 2006;18:637-44 pubmed
Nguyen A, Stebbins E, Henson M, O Young G, Choi S, Quon D, et al. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation. Exp Cell Res. 2006;312:1909-23 pubmed
Neurohr C, Nishimura S, Sheppard D. Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. Am J Respir Cell Mol Biol. 2006;35:252-9 pubmed
Letuve S, Lajoie Kadoch S, Audusseau S, Rothenberg M, Fiset P, Ludwig M, et al. IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts. J Allergy Clin Immunol. 2006;117:590-6 pubmed
Yue Z, Jiang T, Widelitz R, Chuong C. Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia. Proc Natl Acad Sci U S A. 2006;103:951-5 pubmed
Puxeddu I, Bader R, Piliponsky A, Reich R, Levi Schaffer F, Berkman N. The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. J Allergy Clin Immunol. 2006;117:103-10 pubmed
Jung Y, Wang J, Schneider A, Sun Y, Koh Paige A, Osman N, et al. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing. Bone. 2006;38:497-508 pubmed
Dulos J, van der Vleuten M, Kavelaars A, Heijnen C, Boots A. CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum. 2005;52:770-8 pubmed
Ogden C, Pound J, Batth B, Owens S, Johannessen I, Wood K, et al. Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma. J Immunol. 2005;174:3015-23 pubmed
Mesples B, Fontaine R, Lelievre V, Launay J, Gressens P. Neuronal TGF-beta1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice. Neurobiol Dis. 2005;18:193-205 pubmed
Gunnlaugsdottir B, Maggadottir S, Ludviksson B. Anti-CD28-induced co-stimulation and TCR avidity regulates the differential effect of TGF-beta1 on CD4+ and CD8+ naïve human T-cells. Int Immunol. 2005;17:35-44 pubmed
Nagineni C, Kutty V, Detrick B, Hooks J. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J Cell Physiol. 2005;203:35-43 pubmed
Tardif G, Hum D, Pelletier J, Boileau C, Ranger P, Martel Pelletier J. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts. Arthritis Rheum. 2004;50:2521-30 pubmed
Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R. IL-22 increases the innate immunity of tissues. Immunity. 2004;21:241-54 pubmed
Wildemann B, Schmidmaier G, Brenner N, Hüning M, Stange R, Haas N, et al. Quantification, localization, and expression of IGF-I and TGF-beta1 during growth factor-stimulated fracture healing. Calcif Tissue Int. 2004;74:388-97 pubmed
Phillips T. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis. 2004;25:1652-9 pubmed
Wildemann B, Bamdad P, Holmer C, Haas N, Raschke M, Schmidmaier G. Local delivery of growth factors from coated titanium plates increases osteotomy healing in rats. Bone. 2004;34:862-8 pubmed
Bechara R, Brown L, Roman J, Joshi P, Guidot D. Transforming growth factor beta1 expression and activation is increased in the alcoholic rat lung. Am J Respir Crit Care Med. 2004;170:188-94 pubmed
Torrealba J, Katayama M, Fechner J, Jankowska Gan E, Kusaka S, Xu Q, et al. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. J Immunol. 2004;172:5753-64 pubmed
Zheng S, Wang J, Gray J, Soucier H, Horwitz D. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. J Immunol. 2004;172:5213-21 pubmed
Studer R, Bergman R, Stubbs T, Decker K. Chondrocyte response to growth factors is modulated by p38 mitogen-activated protein kinase inhibition. Arthritis Res Ther. 2004;6:R56-R64 pubmed
Leach R, Kilburn B, Wang J, Liu Z, Romero R, Armant D. Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype. Dev Biol. 2004;266:223-37 pubmed
Chen W, Jin W, Hardegen N, Lei K, Li L, Marinos N, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med. 2003;198:1875-86 pubmed
Ashcroft G, Mills S, Lei K, Gibbons L, Jeong M, Taniguchi M, et al. Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor. J Clin Invest. 2003;111:1309-18 pubmed
Khattri R, Cox T, Yasayko S, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol. 2003;4:337-42 pubmed
Huaux F, Liu T, McGarry B, Ullenbruch M, Phan S. Dual roles of IL-4 in lung injury and fibrosis. J Immunol. 2003;170:2083-92 pubmed
Scharstuhl A, van Beuningen H, Vitters E, van der Kraan P, van den Berg W. Loss of transforming growth factor counteraction on interleukin 1 mediated effects in cartilage of old mice. Ann Rheum Dis. 2002;61:1095-8 pubmed
Huaux F, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier J, et al. A profibrotic function of IL-12p40 in experimental pulmonary fibrosis. J Immunol. 2002;169:2653-61 pubmed
Zhao W, Kobayashi M, Ding W, Yuan L, Seth P, Cornain S, et al. Suppression of in vivo tumorigenicity of rat hepatoma cell line KDH-8 cells by soluble TGF-beta receptor type II. Cancer Immunol Immunother. 2002;51:381-8 pubmed
Rosado E, Schwartz Z, Sylvia V, Dean D, Boyan B. Transforming growth factor-beta1 regulation of growth zone chondrocytes is mediated by multiple interacting pathways. Biochim Biophys Acta. 2002;1590:1-15 pubmed
Schmidt A, Göpfert C, Vlodavsky I, Volker W, Buddecke E. Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta. Eur J Cell Biol. 2002;81:138-44 pubmed
Liu X, Kohyama T, Wang H, Zhu Y, Wen F, Kim H, et al. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells. Am J Physiol Lung Cell Mol Physiol. 2002;282:L1049-56 pubmed
Cashman J, Clark Lewis I, Eaves A, Eaves C. Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice. Blood. 2002;99:792-9 pubmed
Farah I, Mola P, Kariuki T, Nyindo M, Blanton R, King C. Repeated exposure induces periportal fibrosis in Schistosoma mansoni-infected baboons: role of TGF-beta and IL-4. J Immunol. 2000;164:5337-43 pubmed
Desfaits A, Raymond J, Muizelaar J. Growth factors stimulate neointimal cells in vitro and increase the thickness of the neointima formed at the neck of porcine aneurysms treated by embolization. Stroke. 2000;31:498-507 pubmed
Mozes M, Hodics T, Kopp J. Isoform specificity of commercially-available anti-TGF-beta antibodies. J Immunol Methods. 1999;225:87-93 pubmed
Akagi Y, Liu W, Zebrowski B, Xie K, Ellis L. Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I. Cancer Res. 1998;58:4008-14 pubmed
产品信息
品牌 :
R&D Systems
master code :
240-B
SKU号 :
240-B-002
产品名称 :
重组人类TGF乙1蛋白
描述 :
The Recombinant Human TGF-beta 1 Protein from R&D Systems is derived from CHO. The Recombinant Human TGF-beta 1 Protein has been validated for the following applications: Bioactivity.
靶标 :
TGF乙1
类别 :
蛋白和酶
单位尺寸 :
2 ug (also 10 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
12 kDa, reducing conditions 24 kDa, non-reducing conditions
理论上的分子量 :
12.8 kDa (monomer)
基因符号 :
转化生长因子1
功能细节 :
Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. Tsang, M. et al . (1995) Cytokine 7 :389. The ED50 for this effect is 0.04-0.2 ng/mL. The specific activity of Recombinant Human TGF-beta 1 is approximately 2.5 x 104 U/µg, which is calibrated against human TGF-beta 1 Standard (NIBSC code: 89/514).
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
240-B
accessionNumbers :
P01137
应用 :
Bioactivity
来源 :
Chinese Hamster Ovary cell line, CHO-derived human TGF-beta 1 protein Ala279-Ser390
extended description :
An alternative TGF-beta 1 is now available! 7754-BH is Hek293 expressed
2020美元 :
259
2021美元 :
259美元
产品细节 :
An alternative TGF-beta 1 is now available! 7754-BH is Hek293 expressed
别名 :
CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1, TGFB, TGFB1, TGFbeta, TGFbeta 1, TGF-beta 1 protein, TGF-beta-1, transforming growth factor beta-1, transforming growth factor, beta 1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.