产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类乙神经生长因子蛋白, CF
目录 :
256-GF-100/CF
规格 :
100微克
价格 :
299美元
更多信息或购买 :
文章摘录数: 42
参考文献
Regua A, Aguayo N, Jalboush S, Doheny D, Manore S, Zhu D, et al. TrkA Interacts with and Phosphorylates STAT3 to Enhance Gene Transcription and Promote Breast Cancer Stem Cells in Triple-Negative and HER2-Enriched Breast Cancers. Cancers (Basel). 2021;13: pubmed 出版商
Sun B, Yang X, Hou F, Yu X, Wang Q, Oh H, et al. Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency. Nat Microbiol. 2021;: pubmed 出版商
Prautsch K, Schmidt A, Paradiso V, Schaefer D, Guzman R, Kalbermatten D, et al. Modulation of Human Adipose Stem Cells' Neurotrophic Capacity Using a Variety of Growth Factors for Neural Tissue Engineering Applications: Axonal Growth, Transcriptional, and Phosphoproteomic Analyses In Vitro. Cells. 2020;9: pubmed 出版商
Xia B, Gao J, Li S, Huang L, Zhu L, Ma T, et al. Mechanical stimulation of Schwann cells promote peripheral nerve regeneration via extracellular vesicle-mediated transfer of microRNA 23b-3p. Theranostics. 2020;10:8974-8995 pubmed 出版商
Yoshida A, Takashima K, Shimonaga T, Kadokura M, Nagase S, Koda S. Establishment of a simple one-step method for oligodendrocyte progenitor cell preparation from rodent brains. J Neurosci Methods. 2020;342:108798 pubmed 出版商
Ebo J, Saunders J, Devine P, Gordon A, Warwick A, Schiffrin B, et al. An in vivo platform to select and evolve aggregation-resistant proteins. Nat Commun. 2020;11:1816 pubmed 出版商
Uesato N, Miyagawa N, Inagaki K, Kakefuda R, Kitagawa Y, Matsuo Y, et al. Pharmacological Properties of JTE-952, an Orally Available and Selective Colony Stimulating Factor 1 Receptor Kinase Inhibitor. Biol Pharm Bull. 2020;43:325-333 pubmed 出版商
Nickolls A, Lee M, Espinoza D, Szczot M, Lam R, Wang Q, et al. Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells. Cell Rep. 2020;30:932-946.e7 pubmed 出版商
Xia B, Gao J, Li S, Huang L, Ma T, Zhao L, et al. Extracellular Vesicles Derived From Olfactory Ensheathing Cells Promote Peripheral Nerve Regeneration in Rats. Front Cell Neurosci. 2019;13:548 pubmed 出版商
McCurdy E, Chung K, Benitez Agosto C, Hengst U. Promotion of Axon Growth by the Secreted End of a Transcription Factor. Cell Rep. 2019;29:363-377.e5 pubmed 出版商
Baumeister D, Eich W, Saft S, Geisel O, Hellweg R, Finn A, et al. No evidence for altered plasma NGF and BDNF levels in fibromyalgia patients. Sci Rep. 2019;9:13667 pubmed 出版商
Kizilyer A, Singh M, Singh V, Suwunnakorn S, Palis J, Maggirwar S. Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis. Sci Rep. 2019;9:2781 pubmed 出版商
Poole A, Frigotto L, Smith M, Baar C, Ivanova Berndt G, Jaulent A, et al. A C-terminal cysteine residue is required for peptide-based inhibition of the NGF/TrkA interaction at nM concentrations: implications for peptide-based analgesics. Sci Rep. 2019;9:930 pubmed 出版商
Deardorff P, McKay T, Wang S, Ghezzi C, Cairns D, Abbott R, et al. Modeling Diabetic Corneal Neuropathy in a 3D In Vitro Cornea System. Sci Rep. 2018;8:17294 pubmed 出版商
Kirino K, Nakahata T, Taguchi T, Saito M. Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition. Sci Rep. 2018;8:12865 pubmed 出版商
Miladinovic T, Ungard R, Linher Melville K, Popovic S, Singh G. Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain. Mol Pain. 2018;14:1744806918776467 pubmed 出版商
Gomez D, Byers L, Nilsson M, Diao L, Wang J, Li L, et al. Integrative proteomic and transcriptomic analysis provides evidence for TrkB (NTRK2) as a therapeutic target in combination with tyrosine kinase inhibitors for non-small cell lung cancer. Oncotarget. 2018;9:14268-14284 pubmed 出版商
Martin J, Chen J, Neidleman J, Tatsumi K, Hu J, Giudice L, et al. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018;99:336-348 pubmed 出版商
Chun K, Lee S, Kim J, Jin E, Kim K, Chun C. Immunohistochemical and immunocytochemical study of mechanoreceptors in anterior cruciate ligament reconstruction with the remnant-preserving technique using Achilles tendon allografts. J Orthop Surg Res. 2017;12:93 pubmed 出版商
Dobson C, Devine P, Phillips J, Higazi D, Lloyd C, Popovic B, et al. Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Sci Rep. 2016;6:38644 pubmed 出版商
Park J, Kang S, Kim J, Tchah H. Nerve Growth Factor Attenuates Apoptosis and Inflammation in the Diabetic Cornea. Invest Ophthalmol Vis Sci. 2016;57:6767-6775 pubmed 出版商
Dustrude E, Moutal A, Yang X, Wang Y, Khanna M, Khanna R. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function. Proc Natl Acad Sci U S A. 2016;113:E8443-E8452 pubmed 出版商
Nishioka H, Tooi N, Isobe T, Nakatsuji N, Aiba K. BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models. Sci Rep. 2016;6:33427 pubmed 出版商
Delbary Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, et al. A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. Brain. 2016;139:1762-82 pubmed 出版商
Gho C, Schomann T, de Groot S, Frijns J, Rivolta M, Neumann M, et al. Isolation, expansion and neural differentiation of stem cells from human plucked hair: a further step towards autologous nerve recovery. Cytotechnology. 2016;68:1849-58 pubmed 出版商
Park K, Lin C, Li K, Lee Y. Effects of Reducing Suppressors of Cytokine Signaling-3 (SOCS3) Expression on Dendritic Outgrowth and Demyelination after Spinal Cord Injury. PLoS ONE. 2015;10:e0138301 pubmed 出版商
Schwab A, Ebert A. Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy. PLoS ONE. 2014;9:e103112 pubmed 出版商
Wan C, Liu J, Nie X, Zhao J, Zhou S, Duan Z, et al. 2, 3, 7, 8-Tetrachlorodibenzo-P-dioxin (TCDD) induces premature senescence in human and rodent neuronal cells via ROS-dependent mechanisms. PLoS ONE. 2014;9:e89811 pubmed 出版商
Gericota B, Anderson J, Mitchell G, Borjesson D, Sturges B, Nolta J, et al. Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury. Stem Cells Transl Med. 2014;3:334-45 pubmed 出版商
Ko J, Mizuno Y, Ohki C, Chikama T, Sonoda K, Kiuchi Y. Neuropeptides released from trigeminal neurons promote the stratification of human corneal epithelial cells. Invest Ophthalmol Vis Sci. 2014;55:125-33 pubmed 出版商
Bowers P, Neben T, Tomlinson G, Dalton J, Altobell L, Zhang X, et al. Humanization of antibodies using heavy chain complementarity-determining region 3 grafting coupled with in vitro somatic hypermutation. J Biol Chem. 2013;288:7688-96 pubmed 出版商
Delcroix G, Curtis K, Schiller P, Montero Menei C. EGF and bFGF pre-treatment enhances neural specification and the response to neuronal commitment of MIAMI cells. Differentiation. 2010;80:213-27 pubmed 出版商
Fjord Larsen L, Kusk P, Tornøe J, Juliusson B, Torp M, Bjarkam C, et al. Long-term delivery of nerve growth factor by encapsulated cell biodelivery in the Göttingen minipig basal forebrain. Mol Ther. 2010;18:2164-72 pubmed 出版商
Schipper H, de Jager W, van Dijk M, Meerding J, Zelissen P, Adan R, et al. A multiplex immunoassay for human adipokine profiling. Clin Chem. 2010;56:1320-8 pubmed 出版商
Foveau B, Ancot F, Leroy C, Petrelli A, Reiss K, Vingtdeux V, et al. Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis. Mol Biol Cell. 2009;20:2495-507 pubmed 出版商
Samah B, Porcheray F, Gras G. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin Exp Immunol. 2008;151:476-86 pubmed 出版商
Paredes D, Granholm A, Bickford P. Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat. Brain Res. 2007;1141:56-64 pubmed
Gallo G. RhoA-kinase coordinates F-actin organization and myosin II activity during semaphorin-3A-induced axon retraction. J Cell Sci. 2006;119:3413-23 pubmed
Young K, Ross T. Elicitation of immunity to HIV type 1 Gag is determined by Gag structure. AIDS Res Hum Retroviruses. 2006;22:99-108 pubmed
Whittlesey K, Shea L. Nerve growth factor expression by PLG-mediated lipofection. Biomaterials. 2006;27:2477-86 pubmed
Adams D, Kao E, Hypolite C, Distefano M, Hu W, Letourneau P. Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV peptide. J Neurobiol. 2005;62:134-47 pubmed
Dollé L, El Yazidi Belkoura I, Adriaenssens E, Nurcombe V, Hondermarck H. Nerve growth factor overexpression and autocrine loop in breast cancer cells. Oncogene. 2003;22:5592-601 pubmed
图像
图像 1 :
安迪生物R&D 256-GF-100/CF 图像 1
Recombinant Human beta-NGF Protein Bioactivity
产品信息
品牌 :
R&D Systems
master code :
256-GF/CF
SKU号 :
256-GF-100/CF
产品名称 :
重组人类乙神经生长因子蛋白, CF
描述 :
The beta-NGF Protein from 256-GF-100/CF is derived from NS0-derived Recombinant Human beta-NGF Protein. The beta-NGF Protein has been validated for the following applications: CAA36832.
靶标 :
乙神经生长因子
类别 :
蛋白和酶
单位尺寸 :
100微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in Acetic Acid.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
物种 :
人类
观察到的分子量 :
13 kDa, reducing conditions
理论上的分子量 :
13.5 kDa
基因符号 :
神经生长因子
功能细节 :
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.2-2 ng/mL.
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
CAA36832
应用 :
Bioactivity
来源 :
NS0-derived Recombinant Human beta-NGF Protein
美元 :
299美元
别名 :
Beta nerve growth factor precursor, beta-nerve growth factor, betaNGF, Beta-NGF, HSAN5, MGC161426, nerve growth factor (beta polypeptide), nerve growth factor, beta subunit, NGFB, NGFBMGC161428
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.