产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类Toll样受体2蛋白, CF
目录 :
2616-TR
规格 :
50微克
价格 :
339美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 8
参考文献
Zheng M, Ambesi A, McKeown Longo P. Role of TLR4 Receptor Complex in the Regulation of the Innate Immune Response by Fibronectin. Cells. 2020;9: pubmed 出版商
Qadri M, Almadani S, Jay G, Elsaid K. Role of CD44 in Regulating TLR2 Activation of Human Macrophages and Downstream Expression of Proinflammatory Cytokines. J Immunol. 2018;200:758-767 pubmed 出版商
Durai P, Shin H, Achek A, Kwon H, Govindaraj R, Panneerselvam S, et al. Toll-like receptor 2 antagonists identified through virtual screening and experimental validation. FEBS J. 2017;284:2264-2283 pubmed 出版商
Lheure C, Grange P, Ollagnier G, Morand P, Desire N, Sayon S, et al. TLR-2 Recognizes Propionibacterium acnes CAMP Factor 1 from Highly Inflammatory Strains. PLoS ONE. 2016;11:e0167237 pubmed 出版商
Langjahr P, Díaz Jiménez D, De la Fuente M, Rubio E, Golenbock D, Bronfman F, et al. Metalloproteinase-dependent TLR2 ectodomain shedding is involved in soluble toll-like receptor 2 (sTLR2) production. PLoS ONE. 2014;9:e104624 pubmed 出版商
Sakaguchi M, Murata H, Yamamoto K, Ono T, Sakaguchi Y, Motoyama A, et al. TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding. PLoS ONE. 2011;6:e23132 pubmed 出版商
Chambers M, Whelan A, Spallek R, Singh M, Coddeville B, Guerardel Y, et al. Non-acylated Mycobacterium bovis glycoprotein MPB83 binds to TLR1/2 and stimulates production of matrix metalloproteinase 9. Biochem Biophys Res Commun. 2010;400:403-8 pubmed 出版商
Zunt S, Burton L, Goldblatt L, Dobbins E, Srinivasan M. Soluble forms of Toll-like receptor 4 are present in human saliva and modulate tumour necrosis factor-alpha secretion by macrophage-like cells. Clin Exp Immunol. 2009;156:285-93 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
2616-TR
SKU号 :
2616-TR-050
产品名称 :
重组人类Toll样受体2蛋白, CF
描述 :
The Recombinant Human TLR2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TLR2 Protein, CF has been validated for the following applications: Binding Activity.
靶标 :
Toll样受体2
类别 :
蛋白和酶
单位尺寸 :
50微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS, NaCl and PEG 3350.
共轭标签 :
未共轭
纯度 :
>85%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
75-80 kDa, reducing conditions
理论上的分子量 :
65.7 kDa
基因符号 :
Toll样受体2
功能细节 :
Measured by its ability to bind biotinylated Pam3CysSerLys4 (PAM3CSK4) (2 µg/mL). The 50% maximum binding is achieved at 0.1-0.5 µg/mL of Recombinant Human TLR2. . Results can vary with different preparations of biotinylated PAM3CSK4. Optimal dilutions should be determined by each laboratory for each application.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
2616-TR
accessionNumbers :
NP_003255
应用 :
结合活性
来源 :
Mouse myeloma cell line, NS0-derived human TLR2 protein Glu21-Leu590, with a C-terminal 10-His tag
2020美元 :
339
2021美元 :
339美元
别名 :
CD282, CD282 antigen, TIL4CD282, toll/interleukin 1 receptor-like 4, Toll/interleukin-1 receptor-like protein 4, toll-like receptor 2
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.