产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组小鼠BACE-1蛋白, CF
目录 :
2976-AS-050
规格 :
50微克
价格 :
423美元
更多信息或购买 :
文章摘录数: 3
| 参考文献 |
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Huttunen H, GUENETTE S, Peach C, Greco C, Xia W, Kim D, et al. HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation. J Biol Chem. 2007;282:28285-95 pubmed
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Hutter Paier B, Huttunen H, Puglielli L, Eckman C, Kim D, Hofmeister A, et al. The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease. Neuron. 2004;44:227-38 pubmed
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产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
2976-AS
SKU号 :
2976-AS-050
产品名称 :
重组小鼠BACE-1蛋白, CF
描述 :
The Recombinant Mouse BACE-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse BACE-1 Protein, CF has been validated for the following applications: Enzyme Activity.
靶标 :
BACE-1
类别 :
蛋白和酶
单位尺寸 :
50微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in Tris and NaCl.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
物种 :
小鼠
观察到的分子量 :
68 kDa, reducing conditions
理论上的分子量 :
50 kDa
基因符号 :
Bace1
功能细节 :
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2 (Catalog # ES004 ). The specific activity is 2 pmol/min/µg, as measured under the described conditions.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P56818
应用 :
酶活性
来源 :
NS0-derived Recombinant Mouse BACE-1 Protein
美元 :
423美元
别名 :
APP beta-secretase, ASP2, Aspartyl protease 2, BACE1, BACEAsp 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1, EC 3.4.23, EC 3.4.23.46, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.