产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
Recombinant Human Latent TGF-beta 1 Protein
目录 :
299-LT
规格 :
5 ug (also 25 ug)
价格 :
329美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 12
参考文献
Guo L, Hou Y, Song L, Zhu S, Lin F, Bai Y. D-Mannose Enhanced Immunomodulation of Periodontal Ligament Stem Cells via Inhibiting IL-6 Secretion. Stem Cells Int. 2018;2018:7168231 pubmed 出版商
Pan F, Xiang H, Yan J, Hong L, Zhang L, Liu Y, et al. Dendritic Cells from Rheumatoid Arthritis Patient Peripheral Blood Induce Th17 Cell Differentiation via miR-363/Integrin ?v/TGF-? Axis. Scand J Immunol. 2017;85:441-449 pubmed 出版商
Jones K, Ballesteros A, Mentink Kane M, Warren J, Rattila S, Malech H, et al. PSG9 Stimulates Increase in FoxP3+ Regulatory T-Cells through the TGF-?1 Pathway. PLoS ONE. 2016;11:e0158050 pubmed 出版商
Zhang J, Wong M, Wong M, Gross S, Chen J, Pollock C, et al. A cationic-independent mannose 6-phosphate receptor inhibitor (PXS64) ameliorates kidney fibrosis by inhibiting activation of transforming growth factor-β1. PLoS ONE. 2015;10:e0116888 pubmed 出版商
Ballesteros A, Mentink Kane M, Warren J, Kaplan G, Dveksler G. Induction and activation of latent transforming growth factor-β1 are carried out by two distinct domains of pregnancy-specific glycoprotein 1 (PSG1). J Biol Chem. 2015;290:4422-31 pubmed 出版商
Tulley S, Chen W. Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-? signaling. J Biol Chem. 2014;289:15280-96 pubmed 出版商
Jelicic K, Cimbro R, Nawaz F, Huang D, Zheng X, Yang J, et al. The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression. Nat Immunol. 2013;14:1256-65 pubmed 出版商
Gonzalez Quesada C, Cavalera M, Biernacka A, Kong P, Lee D, Saxena A, et al. Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation. Circ Res. 2013;113:1331-44 pubmed 出版商
Ma W, Han W, Greer P, Tuder R, Toque H, Wang K, et al. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. J Clin Invest. 2011;121:4548-66 pubmed 出版商
Stockis J, Colau D, Coulie P, Lucas S. Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg. Eur J Immunol. 2009;39:3315-22 pubmed 出版商
Van Aarsen L, Leone D, Ho S, Dolinski B, McCoon P, Lepage D, et al. Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism. Cancer Res. 2008;68:561-70 pubmed 出版商
Torrealba J, Katayama M, Fechner J, Jankowska Gan E, Kusaka S, Xu Q, et al. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. J Immunol. 2004;172:5753-64 pubmed
产品信息
品牌 :
R&D Systems
master code :
299-LT
SKU号 :
299-LT-005
产品名称 :
Recombinant Human Latent TGF-beta 1 Protein
描述 :
The Recombinant Human Latent TGF-beta 1 Protein from R&D Systems is derived from CHO. The Recombinant Human Latent TGF-beta 1 Protein has been validated for the following applications: Bioactivity.
靶标 :
TGF乙1
类别 :
蛋白和酶
单位尺寸 :
5 ug (also 25 ug)
缓冲液 :
Supplied as a 0.2 µm filtered solution in PBS and Glycerol with BSA as a carrier protein.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
物种 :
人类
观察到的分子量 :
36-42 kDa 11 kDa, reducing conditions 80-95 kDa 24 kDa, non-reducing conditions
理论上的分子量 :
28.5 kDa (LAP) 12.8 kDa (Mature), Monomer
基因符号 :
转化生长因子1
功能细节 :
Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. Tsang, M. et al . (1995) Cytokine 7 :389. The ED50 for this effect is 10-70 ng/mL before acid activation and 0.15-0.9 ng/mL after acid activation.
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
299-LT
accessionNumbers :
P01137
应用 :
Bioactivity
来源 :
Chinese Hamster Ovary cell line, CHO-derived human TGF-beta 1 protein Leu30-Ser390
2020美元 :
329
2021美元 :
329美元
别名 :
CEDLAP, DPD1, latency-associated peptide, TGF beta, TGF beta1, TGFB, TGFB1, TGFbeta, TGFbeta 1, TGF-beta 1 protein, TGF-beta-1, transforming growth factor beta-1, transforming growth factor, beta 1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, <= -20 °C under sterile conditions after opening.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.