产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类IL-17A蛋白, CF
目录 :
317-ILB-050
规格 :
50微克
价格 :
359美元
更多信息或购买 :
文章摘录数: 86
参考文献
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Heo Y, Joo Y, Oh H, Park M, Heo Y, Cho M, et al. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett. 2010;127:150-6 pubmed 出版商
Wolk K, Witte E, Warszawska K, Schulze Tanzil G, Witte K, Philipp S, et al. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol. 2009;39:3570-81 pubmed 出版商
Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, et al. IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression. Eur J Immunol. 2009;39:2779-88 pubmed 出版商
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Shahrara S, Pickens S, Dorfleutner A, Pope R. IL-17 induces monocyte migration in rheumatoid arthritis. J Immunol. 2009;182:3884-91 pubmed 出版商
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Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis M, Miossec P. Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes. J Immunol. 2009;182:3112-20 pubmed 出版商
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图像
图像 1 :
安迪生物R&D 317-ILB-050 图像 1
Recombinant Human IL-17A Protein Bioactivity
产品信息
品牌 :
R&D Systems
master code :
317-ILB
SKU号 :
317-ILB-050
产品名称 :
重组人类IL-17A蛋白, CF
描述 :
The IL-17/IL-17A Protein from 317-ILB-050 is derived from E. coli-derived Recombinant Human IL-17A Protein. The IL-17/IL-17A Protein has been validated for the following applications: Q16552.
靶标 :
IL-17/IL-17A
类别 :
蛋白和酶
单位尺寸 :
50微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in HCl.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
物种 :
人类
理论上的分子量 :
16 kDa (monomer)
基因符号 :
IL17A
功能细节 :
Measured by its ability to induce CXCL1/GRO alpha secretion in HT-29 human colon adenocarcinoma cells. The ED50 for this effect is 0.4-4 ng/mL. Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. Yao, Z. et al . (1995) Immunity 3 :811. The ED50 for this effect is 1.5-7.5 ng/mL.
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q16552
应用 :
Bioactivity
extended description :
New rh IL-17A Available! ~4 fold better activity; HEK293 expressed; Lower endotoxin specification!
来源 :
E. coli-derived Recombinant Human IL-17A Protein
美元 :
359美元
产品细节 :
New rh IL-17A Available! ~4 fold better activity; HEK293 expressed; Lower endotoxin specification!
别名 :
CTLA8, CTLA-8, CTLA8cytotoxic T淋巴细胞 丝氨酸酯酶8, 细胞毒性T淋巴细胞 抗原8, 白细胞介素-17, IL17A, IL-17A, IL-17Acytotoxic T淋巴细胞 蛋白8, IL-17CTLA-8, IL17interleukin-17A, 白细胞介素17(细胞毒性T淋巴细胞 丝氨酸酯酶8), 白细胞介素17A
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.