产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类TGF乙RII Fc嵌合体蛋白, CF
目录 :
341-BR
规格 :
50微克
价格 :
459美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 9
参考文献
Kaushansky N, Bakos E, Becker Herman S, Shachar I, Ben Nun A. Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms. J Immunol. 2019;203:1857-1866 pubmed 出版商
Ravi R, Noonan K, Pham V, Bedi R, Zhavoronkov A, Ozerov I, et al. Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy. Nat Commun. 2018;9:741 pubmed 出版商
Olsen O, Skjærvik A, Størdal B, Sundan A, Holien T. TGF-? contamination of purified recombinant GDF15. PLoS ONE. 2017;12:e0187349 pubmed 出版商
Koehler L, Samsonov S, Rother S, Vogel S, Köhling S, Moeller S, et al. Sulfated Hyaluronan Derivatives Modulate TGF-?1:Receptor Complex Formation: Possible Consequences for TGF-?1 Signaling. Sci Rep. 2017;7:1210 pubmed 出版商
Kaushansky N, Eisenstein M, Boura Halfon S, Hansen B, Nielsen C, Milo R, et al. Role of a Novel Human Leukocyte Antigen-DQA1*01:02;DRB1*15:01 Mixed Isotype Heterodimer in the Pathogenesis of "Humanized" Multiple Sclerosis-like Disease. J Biol Chem. 2015;290:15260-78 pubmed 出版商
Ballesteros A, Mentink Kane M, Warren J, Kaplan G, Dveksler G. Induction and activation of latent transforming growth factor-β1 are carried out by two distinct domains of pregnancy-specific glycoprotein 1 (PSG1). J Biol Chem. 2015;290:4422-31 pubmed 出版商
Mizuuchi Y, Aishima S, Ohuchida K, Shindo K, Fujino M, Hattori M, et al. Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition. Lab Invest. 2015;95:193-206 pubmed 出版商
Romero D, Kawano Y, Bengoa N, Walker M, Maltry N, Niehrs C, et al. Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-?/Smad signalling. J Cell Sci. 2013;126:1858-67 pubmed 出版商
Lee W, Kang S, Choi J, Lee S, Shah K, Eynon E, et al. Regulating human Th17 cells via differential expression of IL-1 receptor. Blood. 2010;115:530-40 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
341-BR
SKU号 :
341-BR-050
产品名称 :
重组人类TGF乙RII Fc嵌合体蛋白, CF
描述 :
The Recombinant Human TGF-beta RII Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human TGF-beta RII Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
TGF乙RII
类别 :
蛋白和酶
单位尺寸 :
50微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
物种 :
人类
观察到的分子量 :
59 kDa-66 kDa, reducing conditions
理论上的分子量 :
41.7 kDa (monomer)
基因符号 :
TGFBR2
功能细节 :
Measured by its binding ability in a functional ELISA. When Recombinant Human TGF-beta 1 (Catalog # 240-B/CF ) is immobilized at 0.5 µg/mL, the concentration of Recombinant Human TGF-beta RII Fc Chimera that produces 50% of the optimal binding response is found to be approximately 6-30 ng/mL.
内毒素说明 :
<0.1 EU per 1 µg of the protein by the LAL method.
catalog number base :
341-BR
accessionNumbers :
P37173
应用 :
Bioactivity
来源 :
Mouse myeloma cell line, NS0-derived human TGF-beta RII protein Human TGF-beta RII (Thr23-Asp159) Accession # P37173 MD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
2020美元 :
459
2021美元 :
459美元
别名 :
AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.