产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类亲环素A蛋白, CF
目录 :
3589-CAB-100
规格 :
100微克
价格 :
339美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 8
参考文献
Bernal G, Wu L, Voce D, Weichselbaum R, Yamini B. p52 signaling promotes cellular senescence. Cell Biosci. 2022;12:43 pubmed 出版商
Rosa A, Butt E, Hopper C, Loroch S, Bender M, Schulze H, et al. Cyclophilin A Is Not Acetylated at Lysine-82 and Lysine-125 in Resting and Stimulated Platelets. Int J Mol Sci. 2022;23: pubmed 出版商
Desmarais F, Hervé V, Bergeron K, Ravaut G, Perrotte M, Fyfe Desmarais G, et al. Cerebral Apolipoprotein D Exits the Brain and Accumulates in Peripheral Tissues. Int J Mol Sci. 2021;22: pubmed 出版商
Montagne A, Nation D, Sagare A, Barisano G, Sweeney M, Chakhoyan A, et al. APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline. Nature. 2020;581:71-76 pubmed 出版商
Biswas B, Batista F, Sundaram S, Stanley P. MGAT1 and Complex N-Glycans Regulate ERK Signaling During Spermatogenesis. Sci Rep. 2018;8:2022 pubmed 出版商
Ramachandran S, Vinitha A, Kartha C. Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. Cardiovasc Diabetol. 2016;15:152 pubmed
Heinzmann D, Bangert A, Müller A, von Ungern Sternberg S, Emschermann F, Schönberger T, et al. The Novel Extracellular Cyclophilin A (CyPA) - Inhibitor MM284 Reduces Myocardial Inflammation and Remodeling in a Mouse Model of Troponin I -Induced Myocarditis. PLoS ONE. 2015;10:e0124606 pubmed 出版商
Seizer P, Schonberger T, Schött M, Lang M, Langer H, Bigalke B, et al. EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation. Atherosclerosis. 2010;209:51-7 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
3589-CAB
SKU号 :
3589-CAB-100
产品名称 :
重组人类亲环素A蛋白, CF
描述 :
The Recombinant Human Cyclophilin A Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Cyclophilin A Protein, CF has been validated for the following applications: Enzyme Activity.
靶标 :
亲环素A
类别 :
蛋白和酶
单位尺寸 :
100微克
缓冲液 :
Supplied as a 0.2 µm filtered solution in MES and NaCl.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
17 kDa, reducing conditions
理论上的分子量 :
18 kDa
功能细节 :
Measured by its ability to inhibit calcineurin phosphatase activity in the presence of Cyclosporin A. The IC50 for inhibition of calcineurin activity is 700 nM, as measured under the described conditions.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P62937
应用 :
酶活性
来源 :
E. coli-derived Recombinant Human Cyclophilin A Protein, CF
美元 :
339美元
别名 :
Cyclophilin A, Cyclosporin A-binding protein, CYPA, CYPAMGC12404, CYPH, EC 5.2.1.8, MGC117158, MGC23397, peptidyl-prolyl cis-trans isomerase A, peptidylprolyl isomerase A (cyclophilin A), PPIA, PPIase A, Rotamase, Rotamase A, T cell cyclophilin
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.