Recombinant Human Notch-1 Fc Chimera Protein, CF | 安迪生物R&D 3647-TK-050 产品信息

产品简要

公司名称 :

安迪生物R&D

产品类型 :

蛋白

产品名称 :

Recombinant Human Notch-1 Fc Chimera Protein, CF

3647-TK-050

规格 :

50微克

价格 :

423美元

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 4

参考文献
Maruthachalam B, Barreto K, Hogan D, Kusalik A, Geyer C. Generation of synthetic antibody fragments with optimal complementarity determining region lengths for Notch-1 recognition. Front Microbiol. 2022;13:931307 pubmed 出版商
Li Y, Hickson J, Ambrosi D, Haasch D, Foster Duke K, Eaton L, et al. ABT-165, a Dual Variable Domain Immunoglobulin (DVD-Ig) Targeting DLL4 and VEGF, Demonstrates Superior Efficacy and Favorable Safety Profiles in Preclinical Models. Mol Cancer Ther. 2018;17:1039-1050 pubmed 出版商
Andrawes M, Xu X, Liu H, Ficarro S, Marto J, Aster J, et al. Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1. J Biol Chem. 2013;288:25477-89 pubmed 出版商
Scehnet J, Jiang W, Kumar S, Krasnoperov V, Trindade A, Benedito R, et al. Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion. Blood. 2007;109:4753-60 pubmed

产品信息

品牌 :

R&D Systems, a Bio-Techne Brand

catalog number base :

3647-TK

SKU号 :

3647-TK-050

产品名称 :

Recombinant Human Notch-1 Fc Chimera Protein, CF

描述 :

The Recombinant Human Notch-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Notch-1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

靶标 :

Notch-1

类别 :

蛋白和酶

单位尺寸 :

50微克

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in PBS.

共轭标签 :

未共轭

纯度 :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

物种 :

人类

观察到的分子量 :

115-125 kDa, reducing conditions

理论上的分子量 :

80.1 kDa (monomer)

基因符号 :

NOTCH1

功能细节 :

Measured by its binding ability in a functional ELISA. Immobilized rhNotch-1 Fc Chimera at 5 µg/mL (100 µL/well) can bind rrJagged-1/Fc Chimera with an apparent KD 5 nM in a functional ELISA.

内毒素说明 :

<0.1 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P46531

应用 :

结合活性

来源 :

NS0-derived Recombinant Human Notch-1 Fc Chimera Protein

美元 :

423美元

别名 :

EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.