产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类CD44 Fc嵌合体蛋白, CF
目录 :
3660-Coding sequence蛋白质编码序列
规格 :
50微克
价格 :
394美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 10
参考文献
Yusupov M, Privat Maldonado A, Cordeiro R, Verswyvel H, Shaw P, Razzokov J, et al. Oxidative damage to hyaluronan-CD44 interactions as an underlying mechanism of action of oxidative stress-inducing cancer therapy. Redox Biol. 2021;43:101968 pubmed 出版商
Khan F, Gurung S, Gunassekaran G, Vadevoo S, Chi L, Permpoon U, et al. Identification of novel CD44v6-binding peptides that block CD44v6 and deliver a pro-apoptotic peptide to tumors to inhibit tumor growth and metastasis in mice. Theranostics. 2021;11:1326-1344 pubmed 出版商
Guo J, Chiu C, Wang M, Li F, Chen J. Proteoglycan serglycin promotes non-small cell lung cancer cell migration through the interaction of its glycosaminoglycans with CD44. J Biomed Sci. 2020;27:2 pubmed 出版商
Eggink L, Roby K, Cote R, Kenneth Hoober J. An innovative immunotherapeutic strategy for ovarian cancer: CLEC10A and glycomimetic peptides. J Immunother Cancer. 2018;6:28 pubmed 出版商
Qadri M, Almadani S, Jay G, Elsaid K. Role of CD44 in Regulating TLR2 Activation of Human Macrophages and Downstream Expression of Proinflammatory Cytokines. J Immunol. 2018;200:758-767 pubmed 出版商
Pepin M, Mezouar S, Pegon J, Muczynski V, Adam F, Bianchini E, et al. Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity. Sci Rep. 2016;6:37953 pubmed 出版商
Kellett Clarke H, Stegmann M, Barclay A, Metcalfe C. CD44 Binding to Hyaluronic Acid Is Redox Regulated by a Labile Disulfide Bond in the Hyaluronic Acid Binding Site. PLoS ONE. 2015;10:e0138137 pubmed 出版商
van den Berg L, Cardinaud S, van der Aar A, Sprokholt J, de Jong M, Zijlstra Willems E, et al. Langerhans Cell-Dendritic Cell Cross-Talk via Langerin and Hyaluronic Acid Mediates Antigen Transfer and Cross-Presentation of HIV-1. J Immunol. 2015;195:1763-73 pubmed 出版商
Ayala Lujan J, Vijayakumar V, Gong M, Smith R, Santiago A, Ruiz Perez F. Broad spectrum activity of a lectin-like bacterial serine protease family on human leukocytes. PLoS ONE. 2014;9:e107920 pubmed 出版商
Kohga K, Takehara T, Tatsumi T, Miyagi T, Ishida H, Ohkawa K, et al. Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma. Cancer Res. 2009;69:8050-7 pubmed 出版商
产品信息
品牌 :
R&D Systems
master code :
3660-Coding sequence蛋白质编码序列
SKU号 :
3660-Coding sequence蛋白质编码序列
产品名称 :
重组人类CD44 Fc嵌合体蛋白, CF
描述 :
The Recombinant Human CD44 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD44 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
靶标 :
CD44
类别 :
蛋白和酶
sizes available :
50微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
72-86 kDa, reducing conditions
理论上的分子量 :
48.6 kDa (monomer)
基因符号 :
CD44
功能细节 :
Measured by its ability to bind biotinylated hyaluronan in a functional ELISA with an estimated Kd 0.6 nM.
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P16070
应用 :
结合活性
来源 :
NS0-derived Recombinant Human CD44 Fc Chimera Protein, CF
美元 :
388
美元2023 :
394美元
别名 :
CD44, CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU2CD44 antigen (homing function and Indian blood group system), MDU3, MDU3CDW44, MIC4, MIC4MGC10468, MUTCH-I, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.