产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类PDGF R乙Fc嵌合体蛋白, CF
目录 :
385-PR-100/CF
规格 :
100微克
价格 :
421美元
更多信息或购买 :
文章摘录数: 10
参考文献
Mamer S, Chen S, Weddell J, Palasz A, Wittenkeller A, Kumar M, et al. Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics. Sci Rep. 2017;7:16439 pubmed 出版商
Tao Z, Yang H, Shi Q, Fan Q, Wan L, Lu X. Targeted Delivery to Tumor-associated Pericytes via an Affibody with High Affinity for PDGFRβ Enhances the in vivo Antitumor Effects of Human TRAIL. Theranostics. 2017;7:2261-2276 pubmed 出版商
Stegmann C, Hochdorfer D, Lieber D, Subramanian N, Stöhr D, Laib Sampaio K, et al. A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells. PLoS Pathog. 2017;13:e1006273 pubmed 出版商
Wu Y, Prager A, Boos S, Resch M, Brizic I, Mach M, et al. Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry. PLoS Pathog. 2017;13:e1006281 pubmed 出版商
Lykkemark S, Mandrup O, Jensen M, Just J, Kristensen P. A novel excision selection method for isolation of antibodies binding antigens expressed specifically by rare cells in tissue sections. Nucleic Acids Res. 2017;45:e107 pubmed 出版商
Ding K, Eaton L, Bowley D, Rieser M, Chang Q, Harris M, et al. Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration. MAbs. 2017;9:269-284 pubmed 出版商
Donica C, Cui Y, Shi S, Gutstein H. Platelet-derived growth factor receptor-β antagonism restores morphine analgesic potency against neuropathic pain. PLoS ONE. 2014;9:e97105 pubmed 出版商
Camorani S, Esposito C, Rienzo A, Catuogno S, Iaboni M, Condorelli G, et al. Inhibition of receptor signaling and of glioblastoma-derived tumor growth by a novel PDGFR? aptamer. Mol Ther. 2014;22:828-41 pubmed 出版商
Pfister C, Pfrommer H, Tatagiba M, Roser F. Vascular endothelial growth factor signals through platelet-derived growth factor receptor ? in meningiomas in vitro. Br J Cancer. 2012;107:1702-13 pubmed 出版商
Lacoste E, Martineau I, Gagnon G. Platelet concentrates: effects of calcium and thrombin on endothelial cell proliferation and growth factor release. J Periodontol. 2003;74:1498-507 pubmed
产品信息
品牌 :
R&D Systems
master code :
385-PR/CF
SKU号 :
385-PR-100/CF
产品名称 :
重组人类PDGF R乙Fc嵌合体蛋白, CF
单位尺寸 :
100微克
描述 :
Antibiotic; inhibits bacterial DNA synthesis
靶标 :
PDGF R乙
类别 :
蛋白和酶
别名 :
beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140b, CD140b antigen, EC 2.7.10, EC 2.7.10.1, JTK12, PDGFR, PDGFR1, PDGFRB, PDGF-R-beta, platelet-derived growth factor receptor, beta polypeptide
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
all available conjugate :
未共轭
纯度 :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
观察到的分子量 :
94-124 kDa, reducing conditions
理论上的分子量 :
84 kDa (monomer)
基因符号 :
血小板衍生的生长因子受体b
功能细节 :
Measured by its ability to inhibit the biological activity of PDGF-BB using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 1-3 µg/mL in the presence of 50 ng/mL Recombinant Human PDGF-BB (Catalog # 220-BB ).
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P09619
应用 :
Bioactivity
来源 :
NS0-derived Recombinant Human PDGF R beta Fc Chimera Protein, CF
美元 :
389
Jul-22 :
421美元
sizes available :
100微克
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.