产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类PDGF R乙Fc嵌合体蛋白, CF
目录 :
385-PR-100/CF
规格 :
100微克
价格 :
458美元
更多信息或购买 :
文章摘录数: 13
参考文献
Contreras J, Fujisaki K, Ortega N, Barisano G, Sagare A, Pappas I, et al. Decreased functional connectivity is associated with increased levels of Cerebral Spinal Fluid soluble-PDGFRβ, a marker of blood brain barrier breakdown, in older adults. Res Sq. 2023;: pubmed 出版商
Beckmann R, Jensen K, Fenn S, Speck J, Krause K, Meier A, et al. DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun. 2021;12:708 pubmed 出版商
Park J, Gill K, Aghajani A, Heredia J, Choi H, Oberstein A, et al. Engineered receptors for human cytomegalovirus that are orthogonal to normal human biology. PLoS Pathog. 2020;16:e1008647 pubmed 出版商
Mamer S, Chen S, Weddell J, Palasz A, Wittenkeller A, Kumar M, et al. Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics. Sci Rep. 2017;7:16439 pubmed 出版商
Tao Z, Yang H, Shi Q, Fan Q, Wan L, Lu X. Targeted Delivery to Tumor-associated Pericytes via an Affibody with High Affinity for PDGFRβ Enhances the in vivo Antitumor Effects of Human TRAIL. Theranostics. 2017;7:2261-2276 pubmed 出版商
Stegmann C, Hochdorfer D, Lieber D, Subramanian N, Stöhr D, Laib Sampaio K, et al. A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells. PLoS Pathog. 2017;13:e1006273 pubmed 出版商
Wu Y, Prager A, Boos S, Resch M, Brizic I, Mach M, et al. Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry. PLoS Pathog. 2017;13:e1006281 pubmed 出版商
Lykkemark S, Mandrup O, Jensen M, Just J, Kristensen P. A novel excision selection method for isolation of antibodies binding antigens expressed specifically by rare cells in tissue sections. Nucleic Acids Res. 2017;45:e107 pubmed 出版商
Ding K, Eaton L, Bowley D, Rieser M, Chang Q, Harris M, et al. Generation and characterization of ABBV642, a dual variable domain immunoglobulin molecule (DVD-Ig) that potently neutralizes VEGF and PDGF-BB and is designed for the treatment of exudative age-related macular degeneration. MAbs. 2017;9:269-284 pubmed 出版商
Donica C, Cui Y, Shi S, Gutstein H. Platelet-derived growth factor receptor-β antagonism restores morphine analgesic potency against neuropathic pain. PLoS ONE. 2014;9:e97105 pubmed 出版商
Camorani S, Esposito C, Rienzo A, Catuogno S, Iaboni M, Condorelli G, et al. Inhibition of receptor signaling and of glioblastoma-derived tumor growth by a novel PDGFR? aptamer. Mol Ther. 2014;22:828-41 pubmed 出版商
Pfister C, Pfrommer H, Tatagiba M, Roser F. Vascular endothelial growth factor signals through platelet-derived growth factor receptor ? in meningiomas in vitro. Br J Cancer. 2012;107:1702-13 pubmed 出版商
Lacoste E, Martineau I, Gagnon G. Platelet concentrates: effects of calcium and thrombin on endothelial cell proliferation and growth factor release. J Periodontol. 2003;74:1498-507 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
385-PR/CF
SKU号 :
385-PR-100/CF
产品名称 :
重组人类PDGF R乙Fc嵌合体蛋白, CF
描述 :
The Recombinant Human PDGF R beta Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human PDGF R beta Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
PDGF R乙
类别 :
蛋白和酶
单位尺寸 :
100微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
94-124 kDa, reducing conditions
理论上的分子量 :
84 kDa (monomer)
基因符号 :
血小板衍生的生长因子受体b
功能细节 :
Measured by its ability to inhibit the biological activity of PDGF-BB using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 1-3 µg/mL in the presence of 50 ng/mL Recombinant Human PDGF-BB (Catalog # 220-BB ).
内毒素说明 :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P09619
应用 :
Bioactivity
来源 :
NS0-derived Recombinant Human PDGF R beta Fc Chimera Protein
美元 :
458美元
别名 :
beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140b, CD140b antigen, EC 2.7.10, EC 2.7.10.1, JTK12, PDGFR, PDGFR1, PDGFRB, PDGF-R-beta, platelet-derived growth factor receptor, beta polypeptide
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.