Recombinant Human Angiopoietin-like 4 Protein, CF | 安迪生物R&D 4487-AN-050 产品信息

产品简要

公司名称 :

安迪生物R&D

产品类型 :

蛋白

产品名称 :

Recombinant Human Angiopoietin-like 4 Protein, CF

4487-AN-050

规格 :

50微克

价格 :

493美元

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 13

参考文献
Shen C, Chan R, Lin B, Li N, Huang Y, Chang W, et al. Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation. Theranostics. 2023;13:4650-4666 pubmed 出版商
Hefni E, Menon D, Ma T, Asiedu E, Sultan A, Meiller T, et al. Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway. Cell Signal. 2023;108:110697 pubmed 出版商
Cho D, Ahn M, Cho H, Cho M, Jun J, Kang B, et al. ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation. Exp Mol Med. 2023;55:426-442 pubmed 出版商
Huang J, Zhang S. Overexpressed Neuropilin-1 in Endothelial Cells Promotes Endothelial Permeability through Interaction with ANGPTL4 and VEGF in Kawasaki Disease. Mediators Inflamm. 2021;2021:9914071 pubmed 出版商
Li M, Hu J, Yao L, Gao M. Decreased ANGPTL4 impairs endometrial angiogenesis during peri-implantation period in patients with recurrent implantation failure. J Cell Mol Med. 2020;: pubmed 出版商
Kang Y, Hsu W, Ou C, Tai H, Hsu H, Yeh K, et al. Metformin Mitigates Nickel-Elicited Angiopoietin-Like Protein 4 Expression via HIF-1α for Lung Tumorigenesis. Int J Mol Sci. 2020;21: pubmed 出版商
Zhang T, Kastrenopoulou A, Larrouture Q, Athanasou N, Knowles H. Angiopoietin-like 4 promotes osteosarcoma cell proliferation and migration and stimulates osteoclastogenesis. BMC Cancer. 2018;18:536 pubmed 出版商
Baba K, Kitajima Y, Miyake S, Nakamura J, Wakiyama K, Sato H, et al. Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines. Sci Rep. 2017;7:11127 pubmed 出版商
Dotterweich J, Schlegelmilch K, Keller A, Geyer B, Schneider D, Zeck S, et al. Contact of myeloma cells induces a characteristic transcriptome signature in skeletal precursor cells -Implications for myeloma bone disease. Bone. 2016;93:155-166 pubmed 出版商
Mathieu M, Iampietro M, Chuchana P, Guérit D, Djouad F, Noel D, et al. Involvement of angiopoietin-like 4 in matrix remodeling during chondrogenic differentiation of mesenchymal stem cells. J Biol Chem. 2014;289:8402-12 pubmed 出版商
Robal T, Larsson M, Martin M, Olivecrona G, Lookene A. Fatty acids bind tightly to the N-terminal domain of angiopoietin-like protein 4 and modulate its interaction with lipoprotein lipase. J Biol Chem. 2012;287:29739-52 pubmed 出版商
Knowles H, Cleton Jansen A, Korsching E, Athanasou N. Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4. FASEB J. 2010;24:4648-59 pubmed 出版商
Ma T, Jham B, Hu J, Friedman E, Basile J, Molinolo A, et al. Viral G protein-coupled receptor up-regulates Angiopoietin-like 4 promoting angiogenesis and vascular permeability in Kaposi's sarcoma. Proc Natl Acad Sci U S A. 2010;107:14363-8 pubmed 出版商

产品信息

品牌 :

R&D Systems, a Bio-Techne Brand

catalog number base :

4487-AN

SKU号 :

4487-AN-050

产品名称 :

Recombinant Human Angiopoietin-like 4 Protein, CF

描述 :

The Recombinant Human Angiopoietin-like 4 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Angiopoietin-like 4 Protein, CF has been validated for the following applications: Inhibition Activity.

靶标 :

Angiopoietin-like Protein 4/ANGPTL4

类别 :

蛋白和酶

单位尺寸 :

50微克

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in MOPS, NaCl and CHAPS.

共轭标签 :

未共轭

纯度 :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

物种 :

人类

观察到的分子量 :

50-55 kDa, reducing conditions

理论上的分子量 :

43.6 kDa (monomer)

基因符号 :

ANGPTL4

功能细节 :

Measured by its ability to inhibit lipoprotein lipase activity. Yoshida, K. et al . (2002) J. Lipid Res. 43 :1770. The IC50 value under conditions in which Recombinant Human Lipoprotein Lipase/LPL (Catalog # 9888-LL ) and p-nitrophenyl butyrate are present in 0.1 M sodium phosphate, 0.15 M NaCl, 0.5% Triton® X-100, pH 7.2, is approximately 0.05-2.0 µg/mL.

内毒素说明 :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9BY76

应用 :

抑制作用活性

来源 :

NS0-derived Recombinant Human Angiopoietin-like 4 Protein

美元 :

493美元

别名 :

Angiopoietin like Protein 4, angiopoietin-like 4, Angiopoietin-like protein 4, ANGPTL4, ARP4fasting-induced adipose factor, FIAF, FIAFhepatic angiopoietin-related protein, Hepatic fibrinogen/angiopoietin-related protein, HFARP, HFARPANGPTL2, NL2, peroxisome proliferator-activated receptor (PPAR) gamma inducedangiopoietin-related protein, PGAR, PGARangiopoietin-related protein 4, pp1158, PPARG angiopoietin related protein

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.