产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组小鼠CCL5/RANTES蛋白
目录 :
478-MR-025
规格 :
25微克
价格 :
365美元
更多信息或购买 :
文章摘录数: 20
参考文献
Lin J, Xu Y, Guo P, Chen Y, Zhou J, Xia M, et al. CCL5/CCR5-mediated peripheral inflammation exacerbates blood‒brain barrier disruption after intracerebral hemorrhage in mice. J Transl Med. 2023;21:196 pubmed 出版商
Su Z, Brooks J, Pelker J, Andreyeva T, Sobon H, Gifford R, et al. Studies with neutralizing antibodies suggest CXCL8-mediated neutrophil activation is independent of C-C motif chemokine receptor-like 2 (CCRL2) ligand binding function. PLoS ONE. 2023;18:e0280590 pubmed 出版商
Ho M, Yen C, Hsieh T, Kao T, Chiu J, Chiang Y, et al. CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury. Redox Biol. 2021;46:102067 pubmed 出版商
Ajoy R, Lo Y, Ho M, Chen Y, Wang Y, Chen Y, et al. CCL5 promotion of bioenergy metabolism is crucial for hippocampal synapse complex and memory formation. Mol Psychiatry. 2021;26:6451-6468 pubmed 出版商
Lin Y, Chen Y, Feng W, Hua R, Zhang J, Huo Y, et al. Neddylation pathway alleviates chronic pancreatitis by reducing HIF1α-CCL5-dependent macrophage infiltration. Cell Death Dis. 2021;12:273 pubmed 出版商
Sharif S, Ueda N, Nakatani Y, Wise L, Clifton S, Lateef Z, et al. Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity. Front Microbiol. 2019;10:1421 pubmed 出版商
Böttcher J, Bonavita E, Chakravarty P, Blees H, Cabeza Cabrerizo M, Sammicheli S, et al. NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control. Cell. 2018;172:1022-1037.e14 pubmed 出版商
Lee J, Hoshino A, Inoue K, Saitou T, Uehara S, Kobayashi Y, et al. The HIV co-receptor CCR5 regulates osteoclast function. Nat Commun. 2017;8:2226 pubmed 出版商
Suffee N, Le Visage C, Hlawaty H, Aid Launais R, Vanneaux V, Larghero J, et al. Pro-angiogenic effect of RANTES-loaded polysaccharide-based microparticles for a mouse ischemia therapy. Sci Rep. 2017;7:13294 pubmed 出版商
Pan Y, Smithson L, Ma Y, Hambardzumyan D, Gutmann D. Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival. Oncotarget. 2017;8:32977-32989 pubmed 出版商
Huang S, Walker C, Pennock J, Else K, Muller W, Daniels M, et al. P2X7 receptor-dependent tuning of gut epithelial responses to infection. Immunol Cell Biol. 2017;95:178-188 pubmed 出版商
Costa M, de Negreiros C, Bornstein V, Valente R, Mengel J, Henriques M, et al. Murine IL-17+ Vγ4 T lymphocytes accumulate in the lungs and play a protective role during severe sepsis. BMC Immunol. 2015;16:36 pubmed 出版商
Sottnik J, Dai J, Zhang H, Campbell B, Keller E. Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases. Cancer Res. 2015;75:2151-8 pubmed 出版商
Yang L, Brooks C, Xiao S, Sabbisetti V, Yeung M, Hsiao L, et al. KIM-1-mediated phagocytosis reduces acute injury to the kidney. J Clin Invest. 2015;125:1620-36 pubmed 出版商
Sato S, Zhang X. The Friend leukaemia virus integration 1 (Fli-1) transcription factor affects lupus nephritis development by regulating inflammatory cell infiltration into the kidney. Clin Exp Immunol. 2014;177:102-9 pubmed 出版商
Kimura K, Nagano M, Salazar G, Yamashita T, Tsuboi I, Mishima H, et al. The role of CCL5 in the ability of adipose tissue-derived mesenchymal stem cells to support repair of ischemic regions. Stem Cells Dev. 2014;23:488-501 pubmed 出版商
Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, et al. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5). J Bone Miner Res. 2013;28:2070-80 pubmed 出版商
Kim J, Natarajan S, Vaickus L, Bouchard J, Beal D, Cruikshank W, et al. Diesel exhaust particulates exacerbate asthma-like inflammation by increasing CXC chemokines. Am J Pathol. 2011;179:2730-9 pubmed 出版商
Binder N, Niederreiter B, Hoffmann O, Stange R, Pap T, Stulnig T, et al. Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis. Nat Med. 2009;15:417-24 pubmed 出版商
Chou S, Weng J, Lai H, Liao F, Sun S, Tu P, et al. Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes. J Neurosci. 2008;28:3277-90 pubmed 出版商
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
478-MR
SKU号 :
478-MR-025
产品名称 :
重组小鼠CCL5/RANTES蛋白
描述 :
The Recombinant Mouse CCL5/RANTES Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CCL5/RANTES Protein has been validated for the following applications: Bioactivity.
靶标 :
CCL5/RANTES
类别 :
蛋白和酶
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
小鼠
理论上的分子量 :
7.9 kDa
基因符号 :
Ccl5
功能细节 :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR5. The ED50 for this effect is 1.5-9 ng/mL. Measured by its ability to chemoattract 2-day cultured human monocytes. The ED50 for this effect is 30-100 ng/mL.
内毒素说明 :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q5XZF2
应用 :
Bioactivity
来源 :
E. coli-derived Recombinant Mouse CCL5/RANTES Protein
美元 :
365美元
别名 :
chemokine (C-C motif) ligand 5, D17S136Enormally T-expressed, and presumably secreted, EoCP, Eosinophil chemotactic cytokine, RANTES, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, Small-inducible cytokine A5, T cell-specific protein P228, T-cell specific protein p288, TCP228T-cell-specific protein RANTES
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.