产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
Recombinant Human IL-17A/F Heterodimer Protein, CF
目录 :
5194-IL-025/CF
规格 :
25微克
价格 :
420美元
更多信息或购买 :
文章摘录数: 5
参考文献
Crawford M, Borcherding N, Karandikar N. IL-17 cytokines preferentially act on naïve CD4+ T cells with the IL-17AF heterodimer inducing the greatest functional changes. PLoS ONE. 2023;18:e0285166 pubmed 出版商
Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, et al. Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis. J Exp Med. 2015;212:619-31 pubmed 出版商
Adams K, Abraham V, Spielman D, Kolls J, Rubenstein R, Conner G, et al. IL-17A induces Pendrin expression and chloride-bicarbonate exchange in human bronchial epithelial cells. PLoS ONE. 2014;9:e103263 pubmed 出版商
Chang Y, Al Alwan L, Risse P, Roussel L, Rousseau S, Halayko A, et al. TH17 cytokines induce human airway smooth muscle cell migration. J Allergy Clin Immunol. 2011;127:1046-53.e1-2 pubmed 出版商
Kisand K, Bøe Wolff A, Podkrajsek K, Tserel L, Link M, Kisand K, et al. Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J Exp Med. 2010;207:299-308 pubmed 出版商
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
5194-IL/CF
SKU号 :
5194-IL-025/CF
产品名称 :
Recombinant Human IL-17A/F Heterodimer Protein, CF
描述 :
The Recombinant Human IL-17A/F Heterodimer Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human IL-17A/F Heterodimer Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
IL-17A/F Heterodimer
类别 :
蛋白和酶
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
理论上的分子量 :
IL-17A: 15.7 kDa and IL-17F: 15 kDa
功能细节 :
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. Yao, Z. et al . (1995) Immunity 3 :811. The ED50 for this effect is 3-15 ng/mL.
内毒素说明 :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q16552(IL-17A)Q96PD4(IL-17F)
应用 :
Bioactivity
来源 :
E. coli-derived Recombinant Human IL-17A/F Heterodimer Protein
extended description :
A New rh IL-17A/F is Now Available! It has ~10 fold better activity and is CHO expressed!
美元 :
420美元
产品细节 :
A New rh IL-17A/F is Now Available! It has ~10 fold better activity and is CHO expressed!
别名 :
CTLA8, CTLA8cytotoxic T淋巴细胞 丝氨酸酯酶8, 细胞毒性T淋巴细胞 抗原8, 细胞毒性T淋巴细胞 蛋白8, 白细胞介素-17, IL-17, IL-17A, 白细胞介素17(细胞毒性T淋巴细胞 丝氨酸酯酶8), 白细胞介素17A, 白细胞介素17A
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.