产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类胱氨酸-天冬氨酸蛋白酶3蛋白, CF
目录 :
707-C3-010/CF
规格 :
10微克
价格 :
470美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 16
参考文献
Ai Y, Wang W, Liu F, Fang W, Chen H, Wu L, et al. Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P. Cell Res. 2023;: pubmed 出版商
Bosc E, Anastasie J, Soualmia F, Coric P, Kim J, Wang L, et al. Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics. Cell Death Dis. 2022;13:959 pubmed 出版商
Zhang J, Zhou B, Sun R, Ai Y, Cheng K, Li F, et al. The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8. Cell Res. 2021;: pubmed 出版商
Shen H, Zhu H, Panja D, Gu Q, Li Z. Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling. Nat Commun. 2020;11:2979 pubmed 出版商
Huo D, Zhu J, Chen G, Chen Q, Zhang C, Luo X, et al. Eradication of unresectable liver metastasis through induction of tumour specific energy depletion. Nat Commun. 2019;10:3051 pubmed 出版商
Lee Y, Shu M, Kim J, Kim Y, Sim K, Sung W, et al. Cilostazol protects hepatocytes against alcohol-induced apoptosis via activation of AMPK pathway. PLoS ONE. 2019;14:e0211415 pubmed 出版商
Qin X, Lyu M, Si Y, Yang J, Wu Z, Li J. Alkyne-based surface-enhanced Raman scattering nanoprobe for ratiometric imaging analysis of caspase 3 in live cells and tissues. Anal Chim Acta. 2018;1043:115-122 pubmed 出版商
Zhou B, Zhang J, Liu X, Chen H, Ai Y, Cheng K, et al. Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis. Cell Res. 2018;28:1171-1185 pubmed 出版商
Wang F, Wang L, Wu J, Sokirniy I, Nguyen P, Bregnard T, et al. Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60. PLoS ONE. 2017;12:e0189744 pubmed 出版商
Shim M, Yoon H, Lee S, Jo M, Park J, Kim J, et al. Caspase-3/-7-Specific Metabolic Precursor for Bioorthogonal Tracking of Tumor Apoptosis. Sci Rep. 2017;7:16635 pubmed 出版商
Pérez López A, Soria Gila M, Marsden E, Lilienkampf A, Bradley M. Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells. PLoS ONE. 2016;11:e0153209 pubmed 出版商
Wejda M, Impens F, Takahashi N, Van Damme P, Gevaert K, Vandenabeele P. Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike. J Biol Chem. 2012;287:33983-95 pubmed 出版商
Jarde T, Evans R, McQuillan K, Parry L, Feng G, Alvares B, et al. In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system. Oncogene. 2013;32:883-93 pubmed 出版商
Guery L, Benikhlef N, Gautier T, Paul C, Jego G, Dufour E, et al. Fine-tuning nucleophosmin in macrophage differentiation and activation. Blood. 2011;118:4694-704 pubmed 出版商
Ghosh J, Shenoy A, Clark J. Interactions between important regulatory proteins and human alphaB crystallin. Biochemistry. 2007;46:6308-17 pubmed
Lane D, Côté M, Grondin R, Couture M, Piche A. Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3. Mol Cancer Ther. 2006;5:509-21 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
707-C3/CF
SKU号 :
707-C3-010/CF
产品名称 :
重组人类胱氨酸-天冬氨酸蛋白酶3蛋白, CF
描述 :
The Recombinant Human Caspase-3 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Caspase-3 Protein, CF has been validated for the following applications: Enzyme Activity.
靶标 :
胱氨酸-天冬氨酸蛋白酶3
类别 :
蛋白和酶
单位尺寸 :
10微克
缓冲液 :
Supplied as a 0.2 µm filtered solution in HEPES, NaCl, DTT and Sucrose.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
18 kDa and 10 kDa, reducing conditions
理论上的分子量 :
17 kDa (subunit 1), 11 kDa (subunit 2)
基因符号 :
CASP3
功能细节 :
Measured by its ability to cleave the fluorogenic peptide substrate Ac-DEVD-AFC. The specific activity is 3,000 pmol/min/µg, as measured under the described conditions.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P42574
应用 :
酶活性
来源 :
E. coli-derived Recombinant Human Caspase-3 Protein
美元 :
470美元
别名 :
Apopain, apoptosis-related cysteine protease, CASP3, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, Caspase3, CPP32, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, LICE-1, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.