产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
Recombinant Human IL-17A (Human Cell-expressed) Protein, CF
目录 :
7955-IL-025/CF
规格 :
25 ug (also 10 ug, 100 ug)
价格 :
302美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 14
参考文献
Pavlidis P, Tsakmaki A, Treveil A, Li K, Cozzetto D, Yang F, et al. Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease. Cell Rep. 2022;40:111439 pubmed 出版商
Margetts G, Kleidonas S, Zaibi N, Zaibi M, Edwards K. Evidence for anti-inflammatory effects and modulation of neurotransmitter metabolism by Salvia officinalis L. BMC Complement Med Ther. 2022;22:131 pubmed 出版商
Byrne E, Llorián Salvador M, Tang M, Margariti A, Chen M, Xu H. IL-17A Damages the Blood-Retinal Barrier through Activating the Janus Kinase 1 Pathway. Biomedicines. 2021;9: pubmed 出版商
Sinkeviciute D, Aspberg A, He Y, Bay Jensen A, nnerfjord P. Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study. BMC Rheumatol. 2020;4:30 pubmed 出版商
Sun L, Girnary M, Wang L, Jiao Y, Zeng E, Mercer K, et al. IL-10 Dampens an IL-17-Mediated Periodontitis-Associated Inflammatory Network. J Immunol. 2020;204:2177-2191 pubmed 出版商
Heath J, Scholz G, Veith P, Reynolds E. IL-36γ regulates mediators of tissue homeostasis in epithelial cells. Cytokine. 2019;119:24-31 pubmed 出版商
Muntaka S, Almuhanna Y, Jackson D, Singh S, Afryie Asante A, Camara M, et al. Gamma Interferon and Interleukin-17A Differentially Influence the Response of Human Macrophages and Neutrophils to Pseudomonas aeruginosa Infection. Infect Immun. 2019;87: pubmed 出版商
Chorachoo J, Lambert S, Furnholm T, Roberts L, Reingold L, Auepemkiate S, et al. The small molecule rhodomyrtone suppresses TNF-α and IL-17A-induced keratinocyte inflammatory responses: A potential new therapeutic for psoriasis. PLoS ONE. 2018;13:e0205340 pubmed 出版商
Anderson E, Sastalla I, Earland N, Mahnaz M, Moore I, Otaizo Carrasquero F, et al. Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632. PLoS ONE. 2018;13:e0198862 pubmed 出版商
Bambousková M, Gorvel L, Lampropoulou V, Sergushichev A, Loginicheva E, Johnson K, et al. Electrophilic properties of itaconate and derivatives regulate the IκBζ-ATF3 inflammatory axis. Nature. 2018;556:501-504 pubmed 出版商
Stanfield B, Rider P, Caskey J, Del Piero F, Kousoulas K. Intramuscular vaccination of guinea pigs with the live-attenuated human herpes simplex vaccine VC2 stimulates a transcriptional profile of vaginal Th17 and regulatory Tr1 responses. Vaccine. 2018;36:2842-2849 pubmed 出版商
Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed 出版商
Swindell W, Beamer M, Sarkar M, Loftus S, Fullmer J, Xing X, et al. RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature. Front Immunol. 2018;9:80 pubmed 出版商
Yuki T, Tobiishi M, Kusaka Kikushima A, Ota Y, Tokura Y. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17. PLoS ONE. 2016;11:e0161759 pubmed 出版商
图像
图像 1 :
安迪生物R&D 7955-IL-025/CF 图像 1
Recombinant Human IL-17A (Human Cell-expressed) Protein Bioactivity
产品信息
品牌 :
R&D Systems
master code :
7955-IL/CF
SKU号 :
7955-IL-025/CF
产品名称 :
Recombinant Human IL-17A (Human Cell-expressed) Protein, CF
描述 :
The Recombinant Human IL-17A (Human Cell-expressed) Protein, CF from R&D Systems is derived from HEK293. The Recombinant Human IL-17A (Human Cell-expressed) Protein, CF has been validated for the following applications: Bioactivity.
靶标 :
IL-17/IL-17A
类别 :
蛋白和酶
单位尺寸 :
25 ug (also 10 ug, 100 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS.
共轭标签 :
未共轭
纯度 :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
物种 :
人类
观察到的分子量 :
15-23 kDa, reducing conditions 28-38 kDa, non-reducing conditions
理论上的分子量 :
15.1 kDa (monomer)
基因符号 :
IL17A
功能细节 :
Measured by its ability to induce CXCL1/GRO alpha secretion in HT-29 human colon adenocarcinoma cells. The ED50 for this effect is 0.12-1.2 ng/mL. Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. Yao, Z. et al . (1995) Immunity 3 :811. The ED50 for this effect is 1.5-7.5 ng/mL.
内毒素说明 :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q16552
应用 :
Bioactivity
来源 :
HEK293-derived Recombinant Human IL-17A (Human Cell-expressed) Protein, CF
extended description :
Earn double rewards for reviews
美元 :
302美元
产品细节 :
Earn double rewards for reviews
别名 :
CTLA8, CTLA-8, CTLA8cytotoxic T淋巴细胞 丝氨酸酯酶8, 细胞毒性T淋巴细胞 抗原8, 白细胞介素-17, IL17A, IL-17A, IL-17Acytotoxic T淋巴细胞 蛋白8, IL-17CTLA-8, IL17interleukin-17A, 白细胞介素17(细胞毒性T淋巴细胞 丝氨酸酯酶8), 白细胞介素17A
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.