产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类基质金属蛋白酶-1蛋白, CF
目录 :
901-MP-010
规格 :
10微克
价格 :
410美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 16
参考文献
Wu Y, Tang Y, Zhang X, Chu Z, Liu Y, Tang C. MMP-1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via the JNK and ERK pathway. Int J Biochem Cell Biol. 2020;129:105880 pubmed 出版商
Kumar L, Colomb W, Czerski J, Cox C, Sarkar S. Efficient protease based purification of recombinant matrix metalloprotease-1 in E. coli. Protein Expr Purif. 2018;148:59-67 pubmed 出版商
Willumsen N, Bager C, Leeming D, Bay Jensen A, Karsdal M. Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer. Neoplasia. 2017;19:271-278 pubmed 出版商
Naveed S, Clements D, Jackson D, Philp C, Billington C, Soomro I, et al. Matrix Metalloproteinase-1 Activation Contributes to Airway Smooth Muscle Growth and Asthma Severity. Am J Respir Crit Care Med. 2017;195:1000-1009 pubmed 出版商
Gopal S, Greening D, Zhu H, Simpson R, Mathias R. Transformed MDCK cells secrete elevated MMP1 that generates LAMA5 fragments promoting endothelial cell angiogenesis. Sci Rep. 2016;6:28321 pubmed 出版商
Ichikawa T, Sugiura H, Koarai A, Minakata Y, Kikuchi T, Morishita Y, et al. TLR3 activation augments matrix metalloproteinase production through reactive nitrogen species generation in human lung fibroblasts. J Immunol. 2014;192:4977-88 pubmed 出版商
Djokic J, Fagotto Kaufmann C, Bartels R, Nelea V, Reinhardt D. Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers. J Biol Chem. 2013;288:22821-35 pubmed 出版商
Zhang Y, Mao X, Schwend T, Littlechild S, Conrad G. Resistance of corneal RFUVA–cross-linked collagens and small leucine-rich proteoglycans to degradation by matrix metalloproteinases. Invest Ophthalmol Vis Sci. 2013;54:1014-25 pubmed 出版商
Devel L, Beau F, Amoura M, Vera L, Cassar Lajeunesse E, Garcia S, et al. Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins. J Biol Chem. 2012;287:26647-56 pubmed 出版商
Zhao X, Qureshi F, Eastman P, Manning W, Alexander C, Robinson W, et al. Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis. J Immunol Methods. 2012;378:72-80 pubmed 出版商
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed 出版商
Milward E, Kim K, Szklarczyk A, Nguyen T, Melli G, Nayak M, et al. Cleavage of myelin associated glycoprotein by matrix metalloproteinases. J Neuroimmunol. 2008;193:140-8 pubmed
Lauder S, Carty S, Carpenter C, Hill R, Talamas F, Bondeson J, et al. Interleukin-1beta induced activation of nuclear factor-kappab can be inhibited by novel pharmacological agents in osteoarthritis. Rheumatology (Oxford). 2007;46:752-8 pubmed
Masckauchan T, Agalliu D, Vorontchikhina M, Ahn A, Parmalee N, Li C, et al. Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2. Mol Biol Cell. 2006;17:5163-72 pubmed
Zhou B, Peyton M, He B, Liu C, Girard L, Caudler E, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006;10:39-50 pubmed
Haug C, Lenz C, Diaz F, Bachem M. Oxidized low-density lipoproteins stimulate extracellular matrix metalloproteinase Inducer (EMMPRIN) release by coronary smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004;24:1823-9 pubmed
产品信息
品牌 :
R&D Systems
master code :
901-MP
SKU号 :
901-MP-010
产品名称 :
重组人类基质金属蛋白酶-1蛋白, CF
单位尺寸 :
10微克
描述 :
The Recombinant Human MMP-2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human MMP-2 Protein, CF has been validated for the following applications: Enzyme Activity.
靶标 :
基质金属蛋白酶-1
类别 :
蛋白和酶
别名 :
CLGmatrix metalloprotease 1, CLGN, EC 3.4.24, EC 3.4.24.7, Fibroblast collagenase, interstitial collagenase, matrix metallopeptidase 1 (interstitial collagenase), matrix metalloproteinase 1 (interstitial collagenase), Matrix metalloproteinase-1, MMP1, MMP-1
缓冲液 :
Supplied as a 0.2 µm filtered solution in MES, NaCl, CaCl2 and Brij-35.
共轭标签 :
未共轭
all available conjugate :
未共轭
纯度 :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
物种 :
人类
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
观察到的分子量 :
52-55 kDa, reducing conditions
理论上的分子量 :
52 kDa
基因符号 :
MMP1
功能细节 :
Measured by its ability to cleave a fluorogenic peptide substrate Mca-KPLGL-Dpa-AR-NH2 (Catalog # ES010 ). The specific activity is 400 pmol/min/µg, as measured under the described conditions.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P03956
应用 :
酶活性
来源 :
NS0-derived Recombinant Human MMP-1 Protein, CF
美元 :
379
Jul-22 :
410美元
sizes available :
10微克
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.