产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
重组人类基质金属蛋白酶-2蛋白, CF
目录 :
902-MP-010
规格 :
10微克
价格 :
410美元
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 31
参考文献
Welter A, Wu W, Maurer R, O Quinn T, Chao M, Boyle D, et al. An Investigation of the Altered Textural Property in Woody Breast Myopathy Using an Integrative Omics Approach. Front Physiol. 2022;13:860868 pubmed 出版商
Spiller S, Wippold T, Bellmann Sickert K, Franz S, Saalbach A, Anderegg U, et al. Protease-Triggered Release of Stabilized CXCL12 from Coated Scaffolds in an Ex Vivo Wound Model. Pharmaceutics. 2021;13: pubmed 出版商
Howng B, Winter M, LePage C, Popova I, Krimm M, Vasiljeva O. Novel Ex Vivo Zymography Approach for Assessment of Protease Activity in Tissues with Activatable Antibodies. Pharmaceutics. 2021;13: pubmed 出版商
Uliana F, Vizovišek M, Acquasaliente L, Ciuffa R, Fossati A, Frommelt F, et al. Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen. Nat Commun. 2021;12:1693 pubmed 出版商
Kareskoski M, Vakkamäki J, Laukkanen K, Palviainen M, Johannisson A, Katila T. Matrix metalloproteinase (MMP)-2, MMP-9, semen quality and sperm longevity in fractionated stallion semen. Theriogenology. 2021;164:93-99 pubmed 出版商
Amaral A, Fernandes C, Rebordão M, Szóstek Mioduchowska A, Lukasik K, Pinto Bravo P, et al. Myeloperoxidase Inhibition Decreases the Expression of Collagen and Metallopeptidase in Mare Endometria under In Vitro Conditions. Animals (Basel). 2021;11: pubmed 出版商
Falkowski K, Bielecka E, Thøgersen I, Bocheńska O, Płaza K, Kalińska M, et al. Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)-A CleavEx Based Analysis. Int J Mol Sci. 2020;21: pubmed 出版商
Amaral A, Fernandes C, Rebordão M, Szóstek Mioduchowska A, Lukasik K, Gawronska Kozak B, et al. The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium. Animals (Basel). 2020;10: pubmed 出版商
Devel L, Almer G, Cabella C, Beau F, Bernes M, Oliva P, et al. Biodistribution of Nanostructured Lipid Carriers in Mice Atherosclerotic Model. Molecules. 2019;24: pubmed 出版商
Huo D, Zhu J, Chen G, Chen Q, Zhang C, Luo X, et al. Eradication of unresectable liver metastasis through induction of tumour specific energy depletion. Nat Commun. 2019;10:3051 pubmed 出版商
Ruiz Gómez G, Vogel S, Moller S, Pisabarro M, Hempel U. Glycosaminoglycans influence enzyme activity of MMP2 and MMP2/TIMP3 complex formation - Insights at cellular and molecular level. Sci Rep. 2019;9:4905 pubmed 出版商
Pintus G, Giordo R, Wang Y, Zhu W, Kim S, Zhang L, et al. Reduced vasorin enhances angiotensin II signaling within the aging arterial wall. Oncotarget. 2018;9:27117-27132 pubmed 出版商
Gioia M, Fasciglione G, Sbardella D, Sciandra F, Casella M, Camerini S, et al. The enzymatic processing of α-dystroglycan by MMP-2 is controlled by two anchoring sites distinct from the active site. PLoS ONE. 2018;13:e0192651 pubmed 出版商
Sasidhar M, Chevooru S, Eickelberg O, Hartung H, Neuhaus O. Downregulation of monocytic differentiation via modulation of CD147 by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors. PLoS ONE. 2017;12:e0189701 pubmed 出版商
Gopcevic K, Rovcanin B, Kekic D, Milasinovic D, Kocic G, Stojanovic I. Gelatinases A and B and Antioxidant Enzyme Activity in the Early Phase of Acute Myocardial Infarction. Folia Biol (Praha). 2017;63:20-26 pubmed
Pei S, Yang X, Wang H, Zhang H, Zhou B, Zhang D, et al. Plantamajoside, a potential anti-tumor herbal medicine inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of matrix metalloproteinase-9 and -2. BMC Cancer. 2015;15:965 pubmed 出版商
Kløverpris S, Mikkelsen J, Pedersen J, Jepsen M, Laursen L, Petersen S, et al. Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A. J Biol Chem. 2015;290:21915-24 pubmed 出版商
Wade R, Bassin E, Rodell C, Burdick J. Protease-degradable electrospun fibrous hydrogels. Nat Commun. 2015;6:6639 pubmed 出版商
Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia A, et al. ADAM8 as a drug target in pancreatic cancer. Nat Commun. 2015;6:6175 pubmed 出版商
Temma T, Hanaoka H, Yonezawa A, Kondo N, Sano K, Sakamoto T, et al. Investigation of a MMP-2 activity-dependent anchoring probe for nuclear imaging of cancer. PLoS ONE. 2014;9:e102180 pubmed 出版商
Gu Z, Liu F, Tonkova E, Lee S, Tschumperlin D, Brenner M. Soft matrix is a natural stimulator for cellular invasiveness. Mol Biol Cell. 2014;25:457-69 pubmed 出版商
Wang L, Cossette S, Rarick K, Gershan J, Dwinell M, Harder D, et al. Astrocytes directly influence tumor cell invasion and metastasis in vivo. PLoS ONE. 2013;8:e80933 pubmed 出版商
Djokic J, Fagotto Kaufmann C, Bartels R, Nelea V, Reinhardt D. Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers. J Biol Chem. 2013;288:22821-35 pubmed 出版商
Zhang Y, Mao X, Schwend T, Littlechild S, Conrad G. Resistance of corneal RFUVA–cross-linked collagens and small leucine-rich proteoglycans to degradation by matrix metalloproteinases. Invest Ophthalmol Vis Sci. 2013;54:1014-25 pubmed 出版商
Devel L, Beau F, Amoura M, Vera L, Cassar Lajeunesse E, Garcia S, et al. Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins. J Biol Chem. 2012;287:26647-56 pubmed 出版商
Tsuchiya S, Simmer J, Hu J, Richardson A, Yamakoshi F, Yamakoshi Y. Astacin proteases cleave dentin sialophosphoprotein (Dspp) to generate dentin phosphoprotein (Dpp). J Bone Miner Res. 2011;26:220-8 pubmed 出版商
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed 出版商
Zhao Z, McCloud B, Fleming R, Klempner M. Borrelia burgdorferi-induced monocyte chemoattractant protein-1 production in vivo and in vitro. Biochem Biophys Res Commun. 2007;358:528-33 pubmed
Borrelli V, di Marzo L, Sapienza P, Colasanti M, Moroni E, Cavallaro A. Role of platelet-derived growth factor and transforming growth factor beta1 the in the regulation of metalloproteinase expressions. Surgery. 2006;140:454-63 pubmed
Zhou B, Peyton M, He B, Liu C, Girard L, Caudler E, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006;10:39-50 pubmed
Haug C, Lenz C, Diaz F, Bachem M. Oxidized low-density lipoproteins stimulate extracellular matrix metalloproteinase Inducer (EMMPRIN) release by coronary smooth muscle cells. Arterioscler Thromb Vasc Biol. 2004;24:1823-9 pubmed
产品信息
品牌 :
R&D Systems
master code :
902-MP
SKU号 :
902-MP-010
产品名称 :
重组人类基质金属蛋白酶-2蛋白, CF
描述 :
The Recombinant Human MMP-2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human MMP-2 Protein, CF has been validated for the following applications: Enzyme Activity.
靶标 :
基质金属蛋白酶-2
类别 :
蛋白和酶
sizes available :
10微克
缓冲液 :
Supplied as a 0.2 µm filtered solution in Tris, CaCl2, NaCl and Brij-35.
共轭标签 :
未共轭
纯度 :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
物种 :
人类
观察到的分子量 :
71 kDa, reducing conditions
理论上的分子量 :
71 kDa
基因符号 :
MMP2
功能细节 :
Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 (Catalog # ES001 ). The specific activity is 1,000 pmol/min/µg, as measured under the described conditions.
内毒素说明 :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P08253
应用 :
酶活性
来源 :
CHO-derived Recombinant Human MMP-2 Protein, CF
美元 :
410
美元2023 :
410美元
别名 :
72 kDa gelatinase, CLG4, CLG4A72 kDa type IV collagenase, collagenase type IV-A, EC 3.4.24, EC 3.4.24.24, Gelatinase A, matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase), matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IVcollagenase), Matrix metalloproteinase-2, matrix metalloproteinase-II, MMP2, MMP-2, MMP-II, MONA, neutrophil gelatinase, TBE-1matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IVcollagenase)
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.