重组人类BACE-1蛋白, CF | 安迪生物R&D 931-AS-050 产品信息

产品简要

公司名称 :

安迪生物R&D

产品类型 :

蛋白

产品名称 :

重组人类BACE-1蛋白, CF

931-AS-050

规格 :

50微克

价格 :

394美元

更多信息或购买 :

安迪生物R&D 产品网页

文章摘录数: 7

参考文献
Kim W, Watanabe H, Lomoio S, Tesco G. Spatiotemporal processing of neural cell adhesion molecules 1 and 2 by BACE1 in vivo. J Biol Chem. 2021;296:100372 pubmed 出版商
Zou Y, Hu J, Huang W, Zhu L, Shao M, Dordoe C, et al. The botanical origin and antioxidant, anti-BACE1 and antiproliferative properties of bee pollen from different regions of South Korea. BMC Complement Med Ther. 2020;20:236 pubmed 出版商
Koirala S, Klein J, Zheng Y, Glenn N, Eisemann T, Fon Tacer K, et al. Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase. Cell Rep. 2020;32:107922 pubmed 出版商
Netzer W, Bettayeb K, Sinha S, Flajolet M, Greengard P, Bustos V. Gleevec shifts APP processing from a Î²-cleavage to a nonamyloidogenic cleavage. Proc Natl Acad Sci U S A. 2017;114:1389-1394 pubmed 出版商
Thomas R, Liddell J, Kidd E. Anti-amyloid precursor protein immunoglobulins inhibit amyloid-? production by steric hindrance. FEBS J. 2011;278:167-78 pubmed 出版商
Ahmed R, Holler C, Webb R, Li F, Beckett T, Murphy M. BACE1 and BACE2 enzymatic activities in Alzheimer's disease. J Neurochem. 2010;112:1045-53 pubmed 出版商
Na C, Jeon S, Zhang G, Olson G, Chae C. Inhibition of amyloid beta-peptide production by blockage of beta-secretase cleavage site of amyloid precursor protein. J Neurochem. 2007;101:1583-95 pubmed

产品信息

品牌 :

R&D Systems

master code :

931-AS

SKU号 :

931-AS-050

产品名称 :

重组人类BACE-1蛋白, CF

描述 :

The Recombinant Human BACE-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human BACE-1 Protein, CF has been validated for the following applications: Enzyme Activity.

靶标 :

BACE-1

类别 :

蛋白和酶

单位尺寸 :

50微克

缓冲液 :

Lyophilized from a 0.2 µm filtered solution in PBS.

共轭标签 :

未共轭

纯度 :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

物种 :

人类

观察到的分子量 :

68-70 kDa and 65-67 kDa, reducing conditions

理论上的分子量 :

50 kDa (Pro form) 47 kDa (Mature form)

基因符号 :

BACE1

功能细节 :

Measured by its ability to cleave a fluorogenic peptide substrate, Mca-SEVNLDAEFRK(Dpn)RR-NH2 (Catalog # ES004 ). The specific activity is 3.5 pmol/min/µg, as measured under the described conditions.

内毒素说明 :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P56817.1

应用 :

酶活性

来源 :

NS0-derived Recombinant Human BACE-1 Protein, CF

美元 :

394美元

别名 :

APP beta-secretase, ASP2, Aspartyl protease 2, BACE1, BACEAsp 2, beta-secretase 1, beta-secretase 1 precursor variant 1, beta-site amyloid beta A4 precursor protein-cleaving enzyme, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, beta-site APP-cleaving enzyme, beta-site APP-cleaving enzyme 1, EC 3.4.23, EC 3.4.23.46, FLJ90568, HSPC104, KIAA1149, Memapsin-2, Membrane-associated aspartic protease 2, transmembrane aspartic proteinase Asp2

储存 :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

更多信息或购买 :

安迪生物R&D 产品网页

公司信息

安迪生物R&D

上海市长宁区延安西路726号华敏翰尊国际大厦24A1

info@rndsystemschina.com.cn

http://www.rndsystemschina.com.cn

21 52380373

公司总部: 美国

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.