产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
TGF乙RII抗体
目录 :
AF-241-NA
规格 :
250 ug (also 25 ug)
价格 :
509美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 中和反应, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 小鼠; 图 4d
Zhang M, Pan X, Fujiwara K, Jurcak N, Muth S, Zhou J, et al. Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism. Signal Transduct Target Ther. 2021;6:366 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 1a
Ma W, Silverman S, Zhao L, Villasmil R, Campos M, Amaral J, et al. Absence of TGFβ signaling in retinal microglia induces retinal degeneration and exacerbates choroidal neovascularization. elife. 2019;8: pubmed 出版商
Windus L, Matigian N, Avery V. Induction of Reactive Bone Stromal Fibroblasts in 3D Models of Prostate Cancer Bone Metastases. Biology (Basel). 2023;12: pubmed 出版商
Kl xfc ck V, Cab x103 u G, Mies L, Bukkems F, van Emst L, Bakker R, et al. TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells. Arthritis Res Ther. 2023;25:30 pubmed 出版商
Trzeciak E, Zimmer N, K xe4 mmerer P, Thiem D, Al Nawas B, Tuettenberg A, et al. GARP Regulates the Immune Capacity of a Human Autologous Platelet Concentrate. Biomedicines. 2022;10: pubmed 出版商
Gringhuis S, Kaptein T, Remmerswaal E, Drewniak A, Wevers B, Theelen B, et al. Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs. Nat Immunol. 2022;23:1735-1748 pubmed 出版商
Zhou X, Li X, Wang R, Hua D, Sun C, Yu L, et al. Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis. Cell Death Dis. 2022;13:818 pubmed 出版商
Hanson I, Pitman K, Altanerova U, Altaner x, Malinen E, Edin N. Low-Dose-Rate Radiation-Induced Secretion of TGF-β3 Together with an Activator in Small Extracellular Vesicles Modifies Low-Dose Hyper-Radiosensitivity through ALK1 Binding. Int J Mol Sci. 2022;23: pubmed 出版商
Ju N, Hayashi H, Shimamura M, Baba S, Yoshida S, Morishita R, et al. Prevention of bleomycin-induced pulmonary fibrosis by a RANKL peptide in mice. Sci Rep. 2022;12:12474 pubmed 出版商
Zimmer N, Krebs F, Zimmer S, Mitzel Rink H, Kumm E, Jurk K, et al. Platelet-Derived GARP Induces Peripheral Regulatory T Cells-Potential Impact on T Cell Suppression in Patients with Melanoma-Associated Thrombocytosis. Cancers (Basel). 2020;12: pubmed 出版商
Lin L, Kost E, Lin C, Valente P, Wang C, Kolonin M, et al. PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer. Cell Rep. 2020;33:108253 pubmed 出版商
Thepmalee C, Panya A, Junking M, Chieochansin T, Yenchitsomanus P. Inhibition of IL-10 and TGF-β receptors on dendritic cells enhances activation of effector T-cells to kill cholangiocarcinoma cells. Hum Vaccin Immunother. 2018;14:1423-1431 pubmed 出版商
Olsen O, Skjærvik A, Størdal B, Sundan A, Holien T. TGF-? contamination of purified recombinant GDF15. PLoS ONE. 2017;12:e0187349 pubmed 出版商
Boyan B, Hyzy S, Pan Q, Scott K, Coutts R, Healey R, et al. 24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats. PLoS ONE. 2016;11:e0161782 pubmed 出版商
Wu S, Majeed S, Evans T, Camus M, Wong N, Schollmeier Y, et al. Clathrin light chains' role in selective endocytosis influences antibody isotype switching. Proc Natl Acad Sci U S A. 2016;113:9816-21 pubmed 出版商
Chaudhry S, Cain S, Morgan A, Dallas S, Shuttleworth C, Kielty C. Fibrillin-1 regulates the bioavailability of TGFbeta1. J Cell Biol. 2007;176:355-67 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
AF-241-NA
SKU号 :
AF-241-NA
产品名称 :
TGF乙RII抗体
描述 :
The Human TGF-beta RII Antibody from R&D Systems is a goat polyclonal antibody to TGF-beta RII. This antibody reacts with human. The Human TGF-beta RII Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair).
靶标 :
TGF乙RII
类别 :
一抗
单位尺寸 :
250 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human TGF-beta RII, Ile24-Asp159, Accession # P37173.2
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
人类
特异性 :
Detects human TGF-beta RII in direct ELISAs and Western blots.
基因符号 :
TGFBR2
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P37173.2
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Neutralization, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
美元 :
509美元
别名 :
AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.