产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
肿瘤坏死因子甲抗体
目录 :
AF-410-NA
规格 :
100 ug (also 25 ug)
价格 :
489美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应, 抑制或激活实验
更多信息或购买 :
文章摘录数: 37
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 人类; 3 ug/ml; 图 4a
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, et al. The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis. Oncogene. 2019;: pubmed 出版商
  • 抑制或激活实验; 小鼠; 0.5 ug/ml; 图 1f
Sul O, Rajasekaran M, Park H, Suh J, Choi H. MicroRNA-29b Enhances Osteoclast Survival by Targeting BCL-2-Modifying Factor after Lipopolysaccharide Stimulation. Oxid Med Cell Longev. 2019;2019:6018180 pubmed 出版商
  • 酶联免疫吸附测定; 小鼠; 图 6
Chuang T, Guo Y, Seki S, Rosen A, Johanson D, Mandell J, et al. LRP1 expression in microglia is protective during CNS autoimmunity. Acta Neuropathol Commun. 2016;4:68 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 5
Xu X, Meng Q, Erben U, Wang P, Glauben R, Kuhl A, et al. Myeloid-derived suppressor cells promote B-cell production of IgA in a TNFR2-dependent manner. Cell Mol Immunol. 2017;14:597-606 pubmed 出版商
Hwang Y, Kim H, Shin E. Effect of rottlerin on astrocyte phenotype polarization after trimethyltin insult in the dentate gyrus of mice. J Neuroinflammation. 2022;19:142 pubmed 出版商
Bai B, Li H, Han L, Mei Y, Hu C, Mei Q, et al. Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis. Mol Med Rep. 2022;25: pubmed 出版商
Theocharidis G, Thomas B, Sarkar D, Mumme H, Pilcher W, Dwivedi B, et al. Single cell transcriptomic landscape of diabetic foot ulcers. Nat Commun. 2022;13:181 pubmed 出版商
Luo Y, Yao F, Hu X, Li Y, Chen Y, Li Z, et al. M1 macrophages impair tight junctions between endothelial cells after spinal cord injury. Brain Res Bull. 2022;180:59-72 pubmed 出版商
AlQranei M, Senbanjo L, Aljohani H, Hamza T, Chellaiah M. Lipopolysaccharide- TLR-4 Axis regulates Osteoclastogenesis independent of RANKL/RANK signaling. BMC Immunol. 2021;22:23 pubmed 出版商
Najjar R, Akhavan N, Pourafshar S, Arjmandi B, Feresin R. Cornus officinalis var. koreana Kitam polyphenol extract decreases pro-inflammatory markers in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages by reducing Akt phosphorylation. J Ethnopharmacol. 2021;270:113734 pubmed 出版商
Yoshida T, Das N, Carpenter A, Izadpanah R, Kumar S, Gautam S, et al. Minocycline reverses IL-17A/TRAF3IP2-mediated p38 MAPK/NF-κB/iNOS/NO-dependent cardiomyocyte contractile depression and death. Cell Signal. 2020;73:109690 pubmed 出版商
Li Z, Zhang C, Du J, Zhao J, Shi M, Jin M, et al. Adipocytes promote tumor progression and induce PD-L1 expression via TNF-α/IL-6 signaling. Cancer Cell Int. 2020;20:179 pubmed 出版商
Takagaki Y, Lee S, Dongqing Z, Kitada M, Kanasaki K, Koya D. Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis. Autophagy. 2020;:1-10 pubmed 出版商
Liu X, Tonello R, Ling Y, Gao Y, Berta T. Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1. J Neuroinflammation. 2019;16:209 pubmed 出版商
Xu Y, Xu Y, Zhu Y, Sun H, Juguilon C, Li F, et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis. Mol Ther. 2020;28:202-216 pubmed 出版商
Wang P, Qi X, Xu G, Liu J, Guo J, Li X, et al. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. Aging (Albany NY). 2019;11:7402-7415 pubmed 出版商
Kim S, Neuendorff N, Earnest D. Role of Proinflammatory Cytokines in Feedback Modulation of Circadian Clock Gene Rhythms by Saturated Fatty Acids. Sci Rep. 2019;9:8909 pubmed 出版商
Zhang X, He D, Gao S, Wei Y, Wang L. Aspergillus fumigatus enhances human NK cell activity by regulating M1 macrophage polarization. Mol Med Rep. 2019;20:1241-1249 pubmed 出版商
Pido Lopez J, Tanudjojo B, Farag S, Bondulich M, Andre R, Tabrizi S, et al. Inhibition of tumour necrosis factor alpha in the R6/2 mouse model of Huntington's disease by etanercept treatment. Sci Rep. 2019;9:7202 pubmed 出版商
Wixey J, Lee K, Miller S, Goasdoue K, Colditz P, Tracey Bjorkman S, et al. Neuropathology in intrauterine growth restricted newborn piglets is associated with glial activation and proinflammatory status in the brain. J Neuroinflammation. 2019;16:5 pubmed 出版商
Widmann C, Gandin C, Petit Paitel A, Lazdunski M, Heurteaux C. The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia. Sci Rep. 2018;8:18062 pubmed 出版商
Righetti R, Dos Santos T, Camargo L, Aristóteles L, Fukuzaki S, de Souza F, et al. Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice. Front Pharmacol. 2018;9:1021 pubmed 出版商
Kremer M, Yalcin I, Goumon Y, Wurtz X, Nexon L, Daniel D, et al. A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline. J Neurosci. 2018;38:9934-9954 pubmed 出版商
Lee C, Moon S, Jeong J, Lee S, Lee M, Yoo S, et al. Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis. Cell Death Dis. 2018;9:401 pubmed 出版商
Zenke K, Muroi M, Tanamoto K. AKT1 distinctively suppresses MyD88-depenedent and TRIF-dependent Toll-like receptor signaling in a kinase activity-independent manner. Cell Signal. 2018;43:32-39 pubmed 出版商
Kottke T, Evgin L, Shim K, Rommelfanger D, Boisgerault N, Zaidi S, et al. Subversion of NK-cell and TNF? Immune Surveillance Drives Tumor Recurrence. Cancer Immunol Res. 2017;5:1029-1045 pubmed 出版商
Lee S, Kwon J, Kim S, Jung K, Cho M. Interferon-gamma regulates inflammatory cell death by targeting necroptosis in experimental autoimmune arthritis. Sci Rep. 2017;7:10133 pubmed 出版商
Oh Y, Kwon Y, Jung B. Anti-inflammatory Effects of the Natural Compounds Cortex Phellodendri and Humulus japonicus on Pelvic Inflammatory Disease in Mice. Int J Med Sci. 2017;14:729-734 pubmed 出版商
Matsushita N, Hassanein M, Martínez Clemente M, Lazaro R, French S, Xie W, et al. Gender difference in NASH susceptibility: Roles of hepatocyte Ikk? and Sult1e1. PLoS ONE. 2017;12:e0181052 pubmed 出版商
Chung K, Chatzigeorgiou A, Economopoulou M, Garcia Martin R, Alexaki V, Mitroulis I, et al. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity. Nat Immunol. 2017;18:654-664 pubmed 出版商
Tsunekawa T, Banno R, Mizoguchi A, Sugiyama M, Tominaga T, Onoue T, et al. Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia. EBioMedicine. 2017;16:172-183 pubmed 出版商
Dempsey C, Rubio Araiz A, Bryson K, Finucane O, Larkin C, Mills E, et al. Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-? and cognitive function in APP/PS1 mice. Brain Behav Immun. 2017;61:306-316 pubmed 出版商
Munoz M, Burghi V, Miquet J, Cervino I, Quiroga D, Mazziotta L, et al. Chronic blockade of the AT2 receptor with PD123319 impairs insulin signaling in C57BL/6 mice. Peptides. 2017;88:37-45 pubmed 出版商
Ha S, Sung J, Choi I, Kim Y. Oryza sativa (Rice) Hull Extract Inhibits Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages by Suppressing Extracellular Signal-regulated Kinase, c-Jun N-terminal Kinase, and Nuclear Factor-κB Activation. Pharmacogn Mag. 2016;12:295-301 pubmed
Lim S, Yuzhalin A, Gordon Weeks A, Muschel R. Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells. Oncogene. 2016;35:5735-5745 pubmed 出版商
Kremer M, Yalcin I, Nexon L, Wurtz X, Ceredig R, Daniel D, et al. The antiallodynic action of pregabalin in neuropathic pain is independent from the opioid system. Mol Pain. 2016;12: pubmed 出版商
Teramachi J, Silbermann R, Yang P, Zhao W, Mohammad K, Guo J, et al. Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo. Leukemia. 2016;30:390-8 pubmed 出版商
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
AF-410-NA
SKU号 :
AF-410-NA
产品名称 :
肿瘤坏死因子甲抗体
描述 :
The Human/Mouse TNF-alpha Antibody from R&D Systems is a goat polyclonal antibody to TNF-alpha. This antibody reacts with human, mouse. The Human/Mouse TNF-alpha Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready, ELISA Capture (Matched Antibody Pair).
靶标 :
肿瘤坏死因子甲
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
E. coli -derived recombinant mouse TNF-alpha , Leu80-Leu235, Accession # P06804
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
人类, 小鼠
特异性 :
Detects mouse TNF-alpha in ELISAs. Detects human and mouse TNF-alpha in Western blots. In sandwich immunoassays, approximately 50% cross-reactivity with recombinant rat TNF-alpha is observed.
基因符号 :
肿瘤坏死因子
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P06804
应用 :
Western Blot, Immunohistochemistry, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
美元 :
489美元
别名 :
APC1 protein, Cachectin, Cachetin, DIF, TNF, TNF, monocyte-derived, TNF-a, TNFA, TNFalpha, TNF-alphacachectin, TNFATNF, macrophage-derived, TNFG1F, TNFSF1A, TNFSF2, TNFSF2TNF superfamily, member 2, tumor necrosis factor, tumor necrosis factor (TNF superfamily, member 2), tumor necrosis factor alpha, Tumor necrosis factor ligand superfamily member 2, tumor necrosis factor-alpha
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.