产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
小鼠PD-L1抗体
目录 :
AF1019-SP
规格 :
25微克
价格 :
135美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪
更多信息或购买 :
文章摘录数: 12
参考文献
Fernandes R, Su L, Nishiga Y, Ren J, Bhuiyan A, Cheng N, et al. Immune receptor inhibition through enforced phosphatase recruitment. Nature. 2020;586:779-784 pubmed 出版商
Lerbs T, Cui L, King M, Chai T, Muscat C, Chung L, et al. CD47 prevents the elimination of diseased fibroblasts in scleroderma. JCI Insight. 2020;5: pubmed 出版商
Philippou Y, Sjoberg H, Murphy E, Alyacoubi S, Jones K, Gordon Weeks A, et al. Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model. Br J Cancer. 2020;123:1089-1100 pubmed 出版商
Schreiber L, Urbiola C, Das K, Spiesschaert B, Kimpel J, Heinemann F, et al. The lytic activity of VSV-GP treatment dominates the therapeutic effects in a syngeneic model of lung cancer. Br J Cancer. 2019;121:647-658 pubmed 出版商
Ritzmann F, Jungnickel C, Vella G, Kamyschnikow A, Herr C, Li D, et al. IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer. Sci Rep. 2019;9:10353 pubmed 出版商
Osum K, Burrack A, Martinov T, Sahli N, Mitchell J, Tucker C, et al. Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes. Sci Rep. 2018;8:8295 pubmed 出版商
Srinivasan P, Wu X, Basu M, Rossi C, Sandler A. PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neuroblastoma model that mimics human disease. PLoS Med. 2018;15:e1002497 pubmed 出版商
Dimitrov V, Bouttier M, Boukhaled G, Salehi Tabar R, Avramescu R, Memari B, et al. Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice. J Biol Chem. 2017;292:20657-20668 pubmed 出版商
Bartee M, Dunlap K, Bartee E. Tumor-Localized Secretion of Soluble PD1 Enhances Oncolytic Virotherapy. Cancer Res. 2017;77:2952-2963 pubmed 出版商
Sung S, Ge Y, Dai C, Wang H, Fu S, Sharma R, et al. Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice. J Immunol. 2017;198:2589-2601 pubmed 出版商
Mascia F, Schloemann D, Cataisson C, McKinnon K, Krymskaya L, Wolcott K, et al. Cell autonomous or systemic EGFR blockade alters the immune-environment in squamous cell carcinomas. Int J Cancer. 2016;139:2593-7 pubmed 出版商
Seifert A, Zeng S, Zhang J, Kim T, Cohen N, Beckman M, et al. PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors. Clin Cancer Res. 2017;23:454-465 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF1019-SP 图像 1
Detection of Mouse PD-L1/B7-H1 antibody by Western Blot.
产品信息
品牌 :
R&D Systems
master code :
AF1019
SKU号 :
AF1019-SP
产品名称 :
小鼠PD-L1抗体
描述 :
The Mouse PD-L1 Antibody from R&D Systems is a goat polyclonal antibody to PD-L1. This antibody reacts with mouse. The Mouse PD-L1 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, CyTOF-ready.
靶标 :
PD-L1
类别 :
一抗
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant mouse PD-L1/B7-H1, Phe19-Thr238, Accession # Q9EP73
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
小鼠
特异性 :
Detects mouse PD-L1/B7-H1 in direct ELISAs and Western blots. In direct ELISAs, less than 20% cross-reactivity with recombinant human PD-L1/B7-H1 is observed.
基因符号 :
CD274
accessionNumbers :
Q9EP73
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, CyTOF-ready
美元2021 :
129
美元2022 :
135美元
别名 :
Avelumab, B7-H, B7H1, B7-H1, B7H1PDCD1L1, CD274, CD274 antigenMGC142294, CD274 molecule, PDCD1L1, PDCD1LG1, PDCD1LG1MGC142296, PDL1, PD-L1, PD-L1B7 homolog 1, PDL1PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.