产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
PD-L1/B7-H1抗体
目录 :
AF1019
规格 :
100 ug (also 25 ug)
价格 :
479美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
小鼠
应用 :
免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 26
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 s7f
Taniguchi H, Caeser R, Chavan S, Zhan Y, Chow A, Manoj P, et al. WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC. Cell Rep. 2022;39:110814 pubmed 出版商
  • 免疫印迹; 小鼠; 图 10p, 10q
Liu J, Wang C, Cheng T, Rixiati Y, Ji C, Deng M, et al. Circadian Clock Disruption Suppresses PDL1+ Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer. Cell Mol Gastroenterol Hepatol. 2021;12:251-276 pubmed 出版商
Zhang W, Pan X, Xu Y, Guo H, Zheng M, Chen X, et al. Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA. Acta Pharm Sin B. 2023;13:2585-2600 pubmed 出版商
Shrestha M, Wang D, Ben David Y, Zacksenhaus E. CDK4/6 inhibitors and the pRB-E2F1 axis suppress PVR and PD-L1 expression in triple-negative breast cancer. Oncogenesis. 2023;12:29 pubmed 出版商
Tseng H, Banerjee S, Qian B, Lai M, Wu T, Hsu T, et al. Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma. Eur J Med Chem. 2023;256:115459 pubmed 出版商
Sato M, Maishi N, Hida Y, Yanagawa Matsuda A, Alam M, Sakakibara Konishi J, et al. Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy. Cancer Med. 2023;12:9760-9773 pubmed 出版商
De Burghgrave M, Louren xe7 o C, Berthault C, Aiello V, Villalba A, Fouque A, et al. Pancreatic Islet Cells Response to IFNγ Relies on Their Spatial Location within an Islet. Cells. 2022;12: pubmed 出版商
Li Y, Wu L, Liu Y, Ma S, Huang B, Feng X, et al. A novel multifunctional anti-PD-L1-CD16a-IL15 induces potent cancer cell killing in PD-L1-positive tumour cells. Transl Oncol. 2022;21:101424 pubmed 出版商
Barley T, Murphy P, Wang X, Bowman B, Mormol J, Mager C, et al. Mitogen-activated protein kinase phosphatase-1 controls PD-L1 expression by regulating type I interferon during systemic Escherichia coli infection. J Biol Chem. 2022;298:101938 pubmed 出版商
Pham T, Spaulding C, Shields M, Metropulos A, Shah D, Khalafalla M, et al. Inhibition of MNKs promotes macrophage immunosuppressive phenotype to limit CD8+ T cell antitumor immunity. JCI Insight. 2022;7: pubmed 出版商
Jin J, Sivakumar I, Mironchik Y, Krishnamachary B, Wildes F, Barnett J, et al. PD-L1 near Infrared Photoimmunotherapy of Ovarian Cancer Model. Cancers (Basel). 2022;14: pubmed 出版商
Ishikura N, Sugimoto M, Yorozu K, Kurasawa M, Kondoh O. Anti‑VEGF antibody triggers the effect of anti‑PD‑L1 antibody in PD‑L1low and immune desert‑like mouse tumors. Oncol Rep. 2022;47: pubmed 出版商
Shi Z, Mori Akiyama Y, Du W, Fultz R, Zhao Y, Ruan W, et al. Loss of H2R Signaling Disrupts Neutrophil Homeostasis and Promotes Inflammation-Associated Colonic Tumorigenesis in Mice. Cell Mol Gastroenterol Hepatol. 2022;13:717-737 pubmed 出版商
Kim J, Jang H, Lee G, Hur Y, Keum J, Jo J, et al. A Novel Kinase Inhibitor AX-0085 Inhibits Interferon-γ-Mediated Induction of PD-L1 Expression and Promotes Immune Reaction to Lung Adenocarcinoma Cells. Cells. 2021;11: pubmed 出版商
Fernandes R, Su L, Nishiga Y, Ren J, Bhuiyan A, Cheng N, et al. Immune receptor inhibition through enforced phosphatase recruitment. Nature. 2020;586:779-784 pubmed 出版商
Lerbs T, Cui L, King M, Chai T, Muscat C, Chung L, et al. CD47 prevents the elimination of diseased fibroblasts in scleroderma. JCI Insight. 2020;5: pubmed 出版商
Philippou Y, Sjoberg H, Murphy E, Alyacoubi S, Jones K, Gordon Weeks A, et al. Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model. Br J Cancer. 2020;123:1089-1100 pubmed 出版商
Schreiber L, Urbiola C, Das K, Spiesschaert B, Kimpel J, Heinemann F, et al. The lytic activity of VSV-GP treatment dominates the therapeutic effects in a syngeneic model of lung cancer. Br J Cancer. 2019;121:647-658 pubmed 出版商
Ritzmann F, Jungnickel C, Vella G, Kamyschnikow A, Herr C, Li D, et al. IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer. Sci Rep. 2019;9:10353 pubmed 出版商
Osum K, Burrack A, Martinov T, Sahli N, Mitchell J, Tucker C, et al. Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes. Sci Rep. 2018;8:8295 pubmed 出版商
Srinivasan P, Wu X, Basu M, Rossi C, Sandler A. PD-L1 checkpoint inhibition and anti-CTLA-4 whole tumor cell vaccination counter adaptive immune resistance: A mouse neuroblastoma model that mimics human disease. PLoS Med. 2018;15:e1002497 pubmed 出版商
Dimitrov V, Bouttier M, Boukhaled G, Salehi Tabar R, Avramescu R, Memari B, et al. Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice. J Biol Chem. 2017;292:20657-20668 pubmed 出版商
Bartee M, Dunlap K, Bartee E. Tumor-Localized Secretion of Soluble PD1 Enhances Oncolytic Virotherapy. Cancer Res. 2017;77:2952-2963 pubmed 出版商
Sung S, Ge Y, Dai C, Wang H, Fu S, Sharma R, et al. Dependence of Glomerulonephritis Induction on Novel Intraglomerular Alternatively Activated Bone Marrow-Derived Macrophages and Mac-1 and PD-L1 in Lupus-Prone NZM2328 Mice. J Immunol. 2017;198:2589-2601 pubmed 出版商
Mascia F, Schloemann D, Cataisson C, McKinnon K, Krymskaya L, Wolcott K, et al. Cell autonomous or systemic EGFR blockade alters the immune-environment in squamous cell carcinomas. Int J Cancer. 2016;139:2593-7 pubmed 出版商
Seifert A, Zeng S, Zhang J, Kim T, Cohen N, Beckman M, et al. PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors. Clin Cancer Res. 2017;23:454-465 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF1019 图像 1
Detection of Mouse PD-L1/B7-H1 antibody by Western Blot.
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
AF1019
SKU号 :
AF1019
产品名称 :
PD-L1/B7-H1抗体
描述 :
The Mouse PD-L1/B7-H1 Antibody from R&D Systems is a goat polyclonal antibody to PD-L1. This antibody reacts with mouse. The Mouse PD-L1/B7-H1 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, CyTOF-ready.
靶标 :
PD-L1/B7-H1
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant mouse PD-L1/B7-H1, Phe19-Thr238, Accession # Q9EP73
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
小鼠
特异性 :
Detects mouse PD-L1/B7-H1 in direct ELISAs and Western blots.
基因符号 :
CD274
accessionNumbers :
Q9EP73
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, CyTOF-ready
美元 :
479美元
别名 :
Avelumab, B7-H, B7H1, B7-H1, B7H1PDCD1L1, CD274, CD274 antigenMGC142294, CD274 molecule, PDCD1L1, PDCD1LG1, PDCD1LG1MGC142296, PDL1, PD-L1, PD-L1B7 homolog 1, PDL1PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.