产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
人类PD-1抗体
目录 :
AF1086-SP
规格 :
25微克
价格 :
135美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 18
参考文献
Glorieux C, Xia X, He Y, Hu Y, Cremer K, Robert A, et al. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021;38:101780 pubmed 出版商
Takasu C, Nishi M, Yoshikawa K, Tokunaga T, Kashihara H, Yoshimoto T, et al. Impact of sidedness of colorectal cancer on tumor immunity. PLoS ONE. 2020;15:e0240408 pubmed 出版商
Deng R, Zuo C, Li Y, Xue B, Xun Z, Guo Y, et al. The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway. Cell Mol Immunol. 2020;17:1163-1179 pubmed 出版商
Eckel Passow J, Ho T, Serie D, Cheville J, Houston Thompson R, Costello B, et al. Concordance of PD-1 and PD-L1 (B7-H1) in paired primary and metastatic clear cell renal cell carcinoma. Cancer Med. 2020;9:1152-1160 pubmed 出版商
Li S, Folkvord J, Kovács K, Wagstaff R, Mwakalundwa G, Rendahl A, et al. Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection. PLoS Pathog. 2019;15:e1007311 pubmed 出版商
Li B, SONG T, Wang F, Yin C, Li Z, Lin J, et al. Tumor-derived exosomal HMGB1 promotes esophageal squamous cell carcinoma progression through inducing PD1+ TAM expansion. Oncogenesis. 2019;8:17 pubmed 出版商
Sampedro Nuñez M, Serrano Somavilla A, Adrados M, Cameselle Teijeiro J, Blanco Carrera C, Cabezas Agricola J, et al. Analysis of expression of the PD-1/PD-L1 immune checkpoint system and its prognostic impact in gastroenteropancreatic neuroendocrine tumors. Sci Rep. 2018;8:17812 pubmed 出版商
Wang F, Li B, Wei Y, Zhao Y, Wang L, Zhang P, et al. Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression. Oncogenesis. 2018;7:41 pubmed 出版商
Du S, McCall N, Park K, Guan Q, Fontina P, Ertel A, et al. Blockade of Tumor-Expressed PD-1 promotes lung cancer growth. Oncoimmunology. 2018;7:e1408747 pubmed 出版商
Fan W, Demers A, Wan Y, Li Q. Altered Ratio of T Follicular Helper Cells to T Follicular Regulatory Cells Correlates with Autoreactive Antibody Response in Simian Immunodeficiency Virus-Infected Rhesus Macaques. J Immunol. 2018;200:3180-3187 pubmed 出版商
Rahman M, McKinnon K, Karpova T, Ball D, Venzon D, Fan W, et al. Associations of Simian Immunodeficiency Virus (SIV)-Specific Follicular CD8+ T Cells with Other Follicular T Cells Suggest Complex Contributions to SIV Viremia Control. J Immunol. 2018;200:2714-2726 pubmed 出版商
Amodio D, Cotugno N, Macchiarulo G, Rocca S, Dimopoulos Y, Castrucci M, et al. Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza Vaccination. J Immunol. 2018;200:538-550 pubmed 出版商
Liu Y, Cheng Y, Xu Y, Wang Z, Du X, Li C, et al. Increased expression of programmed cell death protein 1 on NK cells inhibits NK-cell-mediated anti-tumor function and indicates poor prognosis in digestive cancers. Oncogene. 2017;36:6143-6153 pubmed 出版商
Silveira E, Rogers K, Gumber S, Amancha P, Xiao P, Woollard S, et al. Immune Cell Dynamics in Rhesus Macaques Infected with a Brazilian Strain of Zika Virus. J Immunol. 2017;199:1003-1011 pubmed 出版商
Martinez Murillo P, Tran K, Guenaga J, Lindgren G, Adori M, Feng Y, et al. Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach. Immunity. 2017;46:804-817.e7 pubmed 出版商
Obeid J, Erdag G, Smolkin M, Deacon D, Patterson J, Chen L, et al. PD-L1, PD-L2 and PD-1 expression in metastatic melanoma: Correlation with tumor-infiltrating immune cells and clinical outcome. Oncoimmunology. 2016;5:e1235107 pubmed 出版商
Nghiem P, Bhatia S, Lipson E, Kudchadkar R, Miller N, Annamalai L, et al. PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma. N Engl J Med. 2016;374:2542-52 pubmed 出版商
Vargas Inchaustegui D, Demers A, Shaw J, Kang G, Ball D, Tuero I, et al. Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques. J Immunol. 2016;196:1700-10 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF1086-SP 图像 1
Detection of Human PD-1 antibody by Western Blot.
产品信息
品牌 :
R&D Systems
master code :
AF1086
SKU号 :
AF1086-SP
产品名称 :
人类PD-1抗体
描述 :
The Human PD-1 Antibody from R&D Systems is a goat polyclonal antibody to PD-1. This antibody reacts with human. The Human PD-1 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, CyTOF-ready, ELISA Capture (Matched Antibody Pair).
靶标 :
PD-1
类别 :
一抗
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human PD-1, Leu25-Gln167, Accession # Q8IX89
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
人类
特异性 :
Detects human PD-1 in ELISAs and Western blots. In sandwich ELISAs, less than 2% cross-reactivity with recombinant mouse PD-1 and less than 0.2% cross-reactivity with recombinant human (rh) CD28, rhICOS, and rhCTLA-4 is observed.
基因符号 :
PDCD1
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
Q8IX89
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Blockade of Receptor-ligand Interaction, CyTOF-ready, ELISA Capture (Matched Antibody Pair)
美元2021 :
129
美元2022 :
135美元
别名 :
CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.