产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
TrkB Antibody
目录 :
AF1494
规格 :
100 ug (also 25 ug)
价格 :
489美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 41
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2e
Karpinski B, Maynard T, Bryan C, Yitsege G, Horvath A, Lee N, et al. Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome. Dis Model Mech. 2022;15: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1a
Annamneedi A, Del Angel M, Gundelfinger E, Stork O, Caliskan G. The Presynaptic Scaffold Protein Bassoon in Forebrain Excitatory Neurons Mediates Hippocampal Circuit Maturation: Potential Involvement of TrkB Signalling. Int J Mol Sci. 2021;22: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 0.5 ug/ml; 图 1c
Fiedler D, Sasi M, Blum R, Klinke C, Andreatta M, Pape H, et al. Brain-Derived Neurotrophic Factor/Tropomyosin Receptor Kinase B Signaling Controls Excitability and Long-Term Depression in Oval Nucleus of the BNST. J Neurosci. 2021;41:435-445 pubmed 出版商
  • 免疫印迹; 人类; 1:50; 图 9g
Fulgenzi G, Hong Z, Tomassoni Ardori F, Barella L, Becker J, Barrick C, et al. Novel metabolic role for BDNF in pancreatic β-cell insulin secretion. Nat Commun. 2020;11:1950 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 2b
Alshawaf A, Viventi S, Qiu W, D Abaco G, Nayagam B, Erlichster M, et al. Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells. Sci Rep. 2018;8:603 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫组化; 小鼠; 图 7b
Guimarães Camboa N, Cattaneo P, Sun Y, Moore Morris T, Gu Y, Dalton N, et al. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017;20:345-359.e5 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 1
Schütze S, Orozco I, Jentsch T. KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors. J Biol Chem. 2016;291:5566-75 pubmed 出版商
Moliner R, Girych M, Brunello C, Kovaleva V, Biojone C, Enkavi G, et al. Psychedelics promote plasticity by directly binding to BDNF receptor TrkB. Nat Neurosci. 2023;26:1032-1041 pubmed 出版商
Hovhannisyan A, Lindquist K, Belugin S, Mecklenburg J, Ibrahim T, Tram M, et al. Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets. bioRxiv. 2023;: pubmed 出版商
Schmidbauer D, Fink S, Rousset F, L xf6 wenheim H, Senn P, Glueckert R. Closing the Gap between the Auditory Nerve and Cochlear Implant Electrodes: Which Neurotrophin Cocktail Performs Best for Axonal Outgrowth and Is Electrical Stimulation Beneficial?. Int J Mol Sci. 2023;24: pubmed 出版商
Mohamed O, Abdallah D, Fayez A, Mohamed R, El Abhar H. Morin post-treatment surpassed calpeptin in ameliorating 3-NP-induced cortical neurotoxicity via modulation of glutamate/calpain axis, Kidins220, and BDNF/TrkB/AKT/CREB trajectory. Int Immunopharmacol. 2023;116:109771 pubmed 出版商
Biojone C, C Casarotto P, Cannarozzo C, Fred S, Herrera Rodr xed guez R, Lesnikova A, et al. nNOS-induced tyrosine nitration of TRKB impairs BDNF signaling and restrains neuronal plasticity. Prog Neurobiol. 2023;222:102413 pubmed 出版商
Ilchibaeva T, Tsybko A, Zeug A, M xfc ller F, Guseva D, Bischoff S, et al. Serotonin Receptor 5-HT2A Regulates TrkB Receptor Function in Heteroreceptor Complexes. Cells. 2022;11: pubmed 出版商
De Bacco F, Orzan F, Erriquez J, Casanova E, Barault L, Albano R, et al. ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma. Cell Rep. 2021;36:109455 pubmed 出版商
Sultan N, Amin L, Zaher A, Grawish M, Scheven B. Dental pulp stem cells stimulate neuronal differentiation of PC12 cells. Neural Regen Res. 2021;16:1821-1828 pubmed 出版商
Kampanis V, Tolou Dabbaghian B, Zhou L, Roth W, Puttagunta R. Cyclic Stretch of Either PNS or CNS Located Nerves Can Stimulate Neurite Outgrowth. Cells. 2020;10: pubmed 出版商
Faure L, Wang Y, Kastriti M, Fontanet P, Cheung K, Petitpré C, et al. Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates. Nat Commun. 2020;11:4175 pubmed 出版商
Stupack J, Xiong X, Jiang L, Zhang T, Zhou L, Campos A, et al. Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis. J Neurosci. 2020;40:5908-5921 pubmed 出版商
Xiao D, Deng Q, Guo Y, Huang X, Zou M, Zhong J, et al. Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts. Sci Adv. 2020;6:eaaz5858 pubmed 出版商
Pagella P, Caton J, Meisel C, Mitsiadis T. Ameloblastomas Exhibit Stem Cell Potential, Possess Neurotrophic Properties, and Establish Connections with Trigeminal Neurons. Cells. 2020;9: pubmed 出版商
Gómez Fernández P, Lopez de Lapuente Portilla A, Astobiza I, Mena J, Urtasun A, Altmann V, et al. The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis. Cells. 2020;9: pubmed 出版商
Moon G, Kim S, Jeon M, Lee K, Jang I, Nakamura M, et al. Therapeutic Potential of AAV1-Rheb(S16H) Transduction Against Alzheimer's Disease. J Clin Med. 2019;8: pubmed 出版商
Fred S, Laukkanen L, Brunello C, Vesa L, Göös H, Cardon I, et al. Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2. J Biol Chem. 2019;294:18150-18161 pubmed 出版商
Paixão S, Loschek L, Gaitanos L, Alcalà Morales P, Goulding M, Klein R. Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements. Neuron. 2019;104:749-764.e6 pubmed 出版商
Wang Y, Wu H, Fontanet P, Codeluppi S, Akkuratova N, Petitpré C, et al. A cell fitness selection model for neuronal survival during development. Nat Commun. 2019;10:4137 pubmed 出版商
Acton D, Ren X, Di Costanzo S, Dalet A, Bourane S, Bertocchi I, et al. Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch. Cell Rep. 2019;28:625-639.e6 pubmed 出版商
Richner M, Pallesen L, Ulrichsen M, Poulsen E, Holm T, Login H, et al. Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain. Sci Adv. 2019;5:eaav9946 pubmed 出版商
Wiszniak S, Schwarz Q. Notch signalling defines dorsal root ganglia neuroglial fate choice during early neural crest cell migration. BMC Neurosci. 2019;20:21 pubmed 出版商
Takeoka A, Arber S. Functional Local Proprioceptive Feedback Circuits Initiate and Maintain Locomotor Recovery after Spinal Cord Injury. Cell Rep. 2019;27:71-85.e3 pubmed 出版商
Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, et al. Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019;26:3522-3536.e5 pubmed 出版商
Bartesaghi L, Wang Y, Fontanet P, Wanderoy S, Berger F, Wu H, et al. PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis. Cell Rep. 2019;26:3484-3492.e4 pubmed 出版商
Zhang M, Wang Y, Geng J, Zhou S, Xiao B. Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice. Cell Rep. 2019;26:1419-1431.e4 pubmed 出版商
Patil M, Hovhannisyan A, Akopian A. Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines. PLoS ONE. 2018;13:e0198601 pubmed 出版商
Pérez Rando M, Castillo Gomez E, Bueno Fernandez C, Nacher J. The TrkB agonist 7,8-dihydroxyflavone changes the structural dynamics of neocortical pyramidal neurons and improves object recognition in mice. Brain Struct Funct. 2018;223:2393-2408 pubmed 出版商
Kim S, Moon G, Oh Y, Park J, Shin W, Jeong J, et al. Protection of nigral dopaminergic neurons by AAV1 transduction with Rheb(S16H) against neurotoxic inflammation in vivo. Exp Mol Med. 2018;50:e440 pubmed 出版商
Bernal Sierra Y, Haseleu J, Kozlenkov A, Begay V, Lewin G. Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System. Front Mol Neurosci. 2017;10:70 pubmed 出版商
Chen K, Zhang L, Tan M, Lai C, Li A, Ren C, et al. Treadmill exercise suppressed stress-induced dendritic spine elimination in mouse barrel cortex and improved working memory via BDNF/TrkB pathway. Transl Psychiatry. 2017;7:e1069 pubmed 出版商
Price E, Krasowska Zoladek A, Nanda K, Stachel S, Henze D. Development of a pharmacodynamic biomarker to measure target engagement from inhibition of the NGF-TrkA pathway. J Neurosci Methods. 2017;282:34-42 pubmed 出版商
Lao Peregrín C, Ballesteros J, Fernández M, Zamora Moratalla A, Saavedra A, Gomez Lazaro M, et al. Caffeine-mediated BDNF release regulates long-term synaptic plasticity through activation of IRS2 signaling. Addict Biol. 2017;22:1706-1718 pubmed 出版商
Reed Geaghan E, Wright M, See L, Adelman P, Lee K, Koerber H, et al. Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016;36:4362-76 pubmed 出版商
Usoskin D, Furlan A, Islam S, Abdo H, Lönnerberg P, Lou D, et al. Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing. Nat Neurosci. 2015;18:145-53 pubmed 出版商
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
AF1494
SKU号 :
AF1494
产品名称 :
TrkB Antibody
描述 :
The Human/Mouse/Rat TrkB Antibody from R&D Systems is a goat polyclonal antibody to TrkB. This antibody reacts with human, mouse, rat. The Human/Mouse/Rat TrkB Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Blockade of Receptor-ligand Interaction.
靶标 :
TrkB
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant mouse TrkB, Cys32-His429, Accession # P15209
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
人类, 小鼠, 大鼠
特异性 :
Detects mouse TrkB in direct ELISAs. Detects human, mouse, and rat TrkB in Western blots.
基因符号 :
NTRK2
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P15209
应用 :
Western Blot, Simple Western, Immunohistochemistry, Blockade of Receptor-ligand Interaction
美元 :
489美元
别名 :
BDNF/NT-3 growth factors receptor, EC 2.7.10, EC 2.7.10.1, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, NTRK2, trk-B, TrkB tyrosine kinase, TRKBBDNF-tropomyosine receptor kinase B, tyrosine kinase receptor B
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.