产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
SOST/Sclerostin Antibody
目录 :
AF1589
规格 :
100 ug (also 25 ug)
价格 :
464美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
小鼠
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
文章摘录数: 42
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 4b
Kim S, Henneicke H, Cavanagh L, Macfarlane E, Thai L, Foong D, et al. Osteoblastic glucocorticoid signaling exacerbates high-fat-diet- induced bone loss and obesity. Bone Res. 2021;9:40 pubmed 出版商
  • 免疫组化; 小鼠; 1:100
Teufel S, Köckemann P, Fabritius C, Wolff L, Bertrand J, Pap T, et al. Loss of the WNT9a ligand aggravates the rheumatoid arthritis-like symptoms in hTNF transgenic mice. Cell Death Dis. 2021;12:494 pubmed 出版商
Wei T, Shan Z, Wen X, Zhao N, Shen G. Dynamic alternations of RANKL/OPG ratio expressed by cementocytes in response to orthodontic‑induced external apical root resorption in a rat model. Mol Med Rep. 2022;26: pubmed 出版商
Moriishi T, Ito T, Fukuyama R, Qin X, Komori H, Kaneko H, et al. Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading. Int J Mol Sci. 2022;23: pubmed 出版商
Wang Z, Luo Z, Li F, Cao J, Rao S, Liu Y, et al. Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox. Nat Commun. 2022;13:1453 pubmed 出版商
Kim J, Yang Y, Xie J, Lee O, Kim J, Hong J, et al. Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes. Cell Death Differ. 2022;: pubmed 出版商
Zhao D, Riquelme M, Guda T, Tu C, Xu H, Gu S, et al. Connexin hemichannels with prostaglandin release in anabolic function of bone to mechanical loading. elife. 2022;11: pubmed 出版商
Dixit M, Duran Ortiz S, Yildirim G, Poudel S, Louis L, Bartke A, et al. Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging. Aging Cell. 2021;20:e13505 pubmed 出版商
Jackson E, Lara Castillo N, Akhter M, Dallas M, Scott J, Ganesh T, et al. Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice. Bone Rep. 2021;15:101129 pubmed 出版商
Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, et al. Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020;10:13751 pubmed 出版商
Song J, Pineault K, Dones J, Raines R, Wellik D. Hox genes maintain critical roles in the adult skeleton. Proc Natl Acad Sci U S A. 2020;117:7296-7304 pubmed 出版商
Li J, Xue J, Jing Y, Wang M, Shu R, Xu H, et al. SOST Deficiency Aggravates Osteoarthritis in Mice by Promoting Sclerosis of Subchondral Bone. Biomed Res Int. 2019;2019:7623562 pubmed 出版商
Wehrle E, Tourolle Né Betts D, Kuhn G, Scheuren A, Hofmann S, Muller R. Evaluation of longitudinal time-lapsed in vivo micro-CT for monitoring fracture healing in mouse femur defect models. Sci Rep. 2019;9:17445 pubmed 出版商
Pacicca D, Brown T, Watkins D, Kover K, Yan Y, Prideaux M, et al. Elevated glucose acts directly on osteocytes to increase sclerostin expression in diabetes. Sci Rep. 2019;9:17353 pubmed 出版商
Metzger C, Narayanan S, Elizondo J, Carter A, Zawieja D, Hogan H, et al. DSS-induced colitis produces inflammation-induced bone loss while irisin treatment mitigates the inflammatory state in both gut and bone. Sci Rep. 2019;9:15144 pubmed 出版商
Staines K, Ikpegbu E, Törnqvist A, Dillon S, Javaheri B, Amin A, et al. Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis. BMC Musculoskelet Disord. 2019;20:344 pubmed 出版商
Ohori F, Kitaura H, Marahleh A, Kishikawa A, Ogawa S, Qi J, et al. Effect of TNF-α-Induced Sclerostin on Osteocytes during Orthodontic Tooth Movement. J Immunol Res. 2019;2019:9716758 pubmed 出版商
Pineault K, Song J, Kozloff K, Lucas D, Wellik D. Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life. Nat Commun. 2019;10:3168 pubmed 出版商
Nguyen Yamamoto L, Tanaka K, St Arnaud R, Goltzman D. Vitamin D-regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification. JCI Insight. 2019;4: pubmed 出版商
Lotinun S, Ishihara Y, Nagano K, Kiviranta R, Carpentier V, Neff L, et al. Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression. J Clin Invest. 2019;129:3058-3071 pubmed 出版商
Kamimoto H, Kobayashi Y, Moriyama K. Relaxin 2 carried by magnetically directed liposomes accelerates rat midpalatal suture expansion and subsequent new bone formation. Bone Rep. 2019;10:100202 pubmed 出版商
Saito H, Gasser A, Bolamperti S, Maeda M, Matthies L, Jahn K, et al. TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone. Nat Commun. 2019;10:1354 pubmed 出版商
Inoue M, Ono T, Kameo Y, Sasaki F, Ono T, Adachi T, et al. Forceful mastication activates osteocytes and builds a stout jawbone. Sci Rep. 2019;9:4404 pubmed 出版商
Supakul S, Yao K, Ochi H, Shimada T, Hashimoto K, Sunamura S, et al. Pericytes as a Source of Osteogenic Cells in Bone Fracture Healing. Int J Mol Sci. 2019;20: pubmed 出版商
Kim A, Kim J, Kim A, Sohn Y, Cha J, Bak E, et al. Simvastatin attenuates tibial bone loss in rats with type 1 diabetes and periodontitis. J Transl Med. 2018;16:306 pubmed 出版商
Svandová E, Veselá B, Lesot H, Sadoine J, Poliard A, Matalova E. FasL Modulates Expression of Mmp2 in Osteoblasts. Front Physiol. 2018;9:1314 pubmed 出版商
Xiao L, Fei Y, Hurley M. FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation. Bone Rep. 2018;9:136-144 pubmed 出版商
Yamaguchi Y, Kumagai K, Imai S, Miyatake K, Saito T. Sclerostin is upregulated in the early stage of chondrogenic differentiation, but not required in endochondral ossification in vitro. PLoS ONE. 2018;13:e0201839 pubmed 出版商
Meo Burt P, Xiao L, Hurley M. FGF23 Regulates Wnt/β-Catenin Signaling-Mediated Osteoarthritis in Mice Overexpressing High-Molecular-Weight FGF2. Endocrinology. 2018;159:2386-2396 pubmed 出版商
Javaheri B, Carriero A, Wood M, de Souza R, Lee P, Shefelbine S, et al. Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response. Sci Rep. 2018;8:6636 pubmed 出版商
Narayanan S, Metzger C, Bloomfield S, Zawieja D. Inflammation-induced lymphatic architecture and bone turnover changes are ameliorated by irisin treatment in chronic inflammatory bowel disease. FASEB J. 2018;32:4848-4861 pubmed 出版商
Morrell A, Brown G, Robinson S, Sattler R, Baik A, Zhen G, et al. Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation. Bone Res. 2018;6:6 pubmed 出版商
Nakatani T, Chen T, Johnson J, Westendorf J, Partridge N. The Deletion of Hdac4 in Mouse Osteoblasts Influences Both Catabolic and Anabolic Effects in Bone. J Bone Miner Res. 2018;33:1362-1375 pubmed 出版商
Gardinier J, Rostami N, Juliano L, Zhang C. Bone adaptation in response to treadmill exercise in young and adult mice. Bone Rep. 2018;8:29-37 pubmed 出版商
Sakurai A, Hasegawa T, Kudo A, Shen Z, Nagai T, Abe M, et al. Chronological immunolocalization of sclerostin and FGF23 in the mouse metaphyseal trabecular and cortical bone. Biomed Res. 2017;38:257-267 pubmed 出版商
Cui P, Liu H, Sun J, Amizuka N, Sun Q, Li M. Zoledronate promotes bone formation by blocking osteocyte-osteoblast communication during bone defect healing. Histol Histopathol. 2018;33:89-99 pubmed 出版商
Ramaswamy G, Kim H, Zhang D, Lounev V, WU J, Choi Y, et al. Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways. Sci Rep. 2017;7:45140 pubmed 出版商
Ogura K, Iimura T, Makino Y, Sugie Oya A, Takakura A, Takao Kawabata R, et al. Short-term intermittent administration of parathyroid hormone facilitates osteogenesis by different mechanisms in cancellous and cortical bone. Bone Rep. 2016;5:7-14 pubmed 出版商
Shu R, Bai D, Sheu T, He Y, Yang X, Xue C, et al. Sclerostin Promotes Bone Remodeling in the Process of Tooth Movement. PLoS ONE. 2017;12:e0167312 pubmed 出版商
Metzger C, Narayanan A, Zawieja D, Bloomfield S. Inflammatory Bowel Disease in a Rodent Model Alters Osteocyte Protein Levels Controlling Bone Turnover. J Bone Miner Res. 2017;32:802-813 pubmed 出版商
Chandra A, Lin T, Young T, Tong W, Ma X, Tseng W, et al. Suppression of Sclerostin Alleviates Radiation-Induced Bone Loss by Protecting Bone-Forming Cells and Their Progenitors Through Distinct Mechanisms. J Bone Miner Res. 2017;32:360-372 pubmed 出版商
Amri N, Djolé S, Petit S, Babajko S, Coudert A, Castaneda B, et al. Distorted Patterns of Dentinogenesis and Eruption in Msx2 Null Mutants: Involvement of Sost/Sclerostin. Am J Pathol. 2016;186:2577-87 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF1589 图像 1
Detection of Human and Mouse SOST/Sclerostin antibody by Western Blot.
产品信息
品牌 :
R&D Systems
master code :
AF1589
SKU号 :
AF1589
产品名称 :
SOST/Sclerostin Antibody
描述 :
The Mouse SOST/Sclerostin Antibody from R&D Systems is a goat polyclonal antibody to SOST/Sclerostin. This antibody reacts with mouse. The Mouse SOST/Sclerostin Antibody has been validated for the following applications: Western Blot, Immunohistochemistry.
靶标 :
SOST/Sclerostin
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant mouse SOST/Sclerostin, Gln24-Tyr211, Accession # NP_077769
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
小鼠
特异性 :
Detects mouse SOST/Sclerostin in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human SOST is observed.
基因符号 :
SOST
accessionNumbers :
NP_077769
应用 :
免疫印迹, 免疫组化
美元 :
464美元
别名 :
sclerostin, VBCHsclerosteosis
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.