产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
HIF-1甲抗体
目录 :
AF1935
规格 :
100微克
价格 :
375美元
克隆性 :
多克隆
宿主 :
山羊
共轭标签 :
nonconjugated
反应物种 :
Domestic guinea pig, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 19
出版应用/物种/样品/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 2a
Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti H, et al. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017;8:14583 pubmed 出版商
  • 免疫印迹; 人类; 图 4f
  • 免疫印迹; Domestic guinea pig; 图 4f
Hunt R, Yalamanoglu A, Tumlin J, Schiller T, Baek J, Wu A, et al. A mechanistic investigation of thrombotic microangiopathy associated with IV abuse of Opana ER. Blood. 2017;129:896-905 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4
Espinoza I, Sakiyama M, Ma T, Fair L, Zhou X, Hassan M, et al. Hypoxia on the Expression of Hepatoma Upregulated Protein in Prostate Cancer Cells. Front Oncol. 2016;6:144 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Tholen M, Wolanski J, Stolze B, Chiabudini M, Gajda M, Bronsert P, et al. Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression. J Biol Chem. 2015;290:15758-69 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Palladino M, Shah A, Tyson R, Horvath J, Dugan C, Karpodinis M. Myeloid cell leukemia-1 (Mc1-1) is a candidate target gene of hypoxia-inducible factor-1 (HIF-1) in the testis. Reprod Biol Endocrinol. 2012;10:104 pubmed 出版商
  • 免疫印迹; 人类
Liang D, Ma Y, Liu J, Tropé C, Holm R, Nesland J, et al. The hypoxic microenvironment upgrades stem-like properties of ovarian cancer cells. BMC Cancer. 2012;12:201 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Robador P, San José G, Rodriguez C, Guadall A, Moreno M, Beaumont J, et al. HIF-1-mediated up-regulation of cardiotrophin-1 is involved in the survival response of cardiomyocytes to hypoxia. Cardiovasc Res. 2011;92:247-55 pubmed 出版商
  • 免疫印迹; 小鼠
Joshi D, Patel H, Baker D, Shiwen X, Abraham D, Tsui J. Development of an in vitro model of myotube ischemia. Lab Invest. 2011;91:1241-52 pubmed 出版商
  • 免疫印迹; 人类
Wang B, Wood I, Trayhurn P. Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes. J Endocrinol. 2008;198:127-34 pubmed 出版商
Nakayama T, Otsuka S, Kobayashi T, Okajima H, Matsumoto K, Hagiya Y, et al. Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy. Sci Rep. 2016;6:36478 pubmed 出版商
Quaranta M, Spinello I, Paolillo R, Macchia G, Boe A, Ceccarini M, et al. Identification of ?-Dystrobrevin as a Direct Target of miR-143: Involvement in Early Stages of Neural Differentiation. PLoS ONE. 2016;11:e0156325 pubmed 出版商
Lopez Haber C, Barrio Real L, Casado Medrano V, Kazanietz M. Heregulin/ErbB3 Signaling Enhances CXCR4-Driven Rac1 Activation and Breast Cancer Cell Motility via Hypoxia-Inducible Factor 1α. Mol Cell Biol. 2016;36:2011-26 pubmed 出版商
Zuo R, Gu X, Qi Q, Wang T, Zhao X, Liu J, et al. Warburg-like Glycolysis and Lactate Shuttle in Mouse Decidua during Early Pregnancy. J Biol Chem. 2015;290:21280-91 pubmed 出版商
Li R, Uttarwar L, Gao B, Charbonneau M, Shi Y, Chan J, et al. High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells. J Biol Chem. 2015;290:21603-14 pubmed 出版商
Paolillo R, Spinello I, Quaranta M, Pasquini L, Pelosi E, Lo Coco F, et al. Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells. PLoS ONE. 2015;10:e0126968 pubmed 出版商
Stahr A, Frahm C, Kretz A, Bondeva T, Witte O, Wolf G. Morg1(+/-) heterozygous mice are protected from experimentally induced focal cerebral ischemia. Brain Res. 2012;1482:22-31 pubmed 出版商
Ho J, Metcalf J, Yan M, Turgeon P, Wang J, Chalsev M, et al. Functional importance of Dicer protein in the adaptive cellular response to hypoxia. J Biol Chem. 2012;287:29003-20 pubmed 出版商
Palladino M, Pirlamarla P, McNamara J, Sottas C, Korah N, Hardy M, et al. Normoxic expression of hypoxia-inducible factor 1 in rat Leydig cells in vivo and in vitro. J Androl. 2011;32:307-23 pubmed 出版商
Bollig Fischer A, Dziubinski M, Boyer A, Haddad R, Giroux C, Ethier S. HER-2 signaling, acquisition of growth factor independence, and regulation of biological networks associated with cell transformation. Cancer Res. 2010;70:7862-73 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF1935 图像 1
Detection of Human HIF-1 alpha by Western Blot. Western blot shows lysates of MCF-7 human breast cancer cell line untreated (-) or treated (+) with 150 ╡M CoCl2 for 16 hours. PVDF membrane was probed with 0.5 ╡g/mL of Goat Anti-Human/Mouse/Rat HIF-1 alpha Antigen-affinity Purified Polyclonal Antibody, followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109 ). A specific band was detected for HIF-1 alpha at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1 .
产品信息
SKU号 :
AF1935
描述 :
The Human/Mouse/Rat HIF-1 alpha Antibody from R&D Systems is a goat polyclonal antibody to HIF-1 alpha. This antibody reacts with human, mouse, rat. The Human/Mouse/Rat HIF-1 alpha Antibody has been validated for the following applications: Western Blot, Simple Western, Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Immunocytochemistry, Knockout Validated.
类别 :
一抗
规格 :
100微克
产品名称 :
HIF-1甲抗体
又名 :
ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, BHLHE78, Class E basic helix-loop-helix protein 78, HIF 1A, HIF1 alpha, HIF-1 alpha, HIF-1a, HIF1A, HIF-1-alpha, HIF1-alpha, hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcriptionfactor), hypoxia-inducible factor 1-alpha, Member of PAS protein 1, member of PAS superfamily 1, MOP1HIF1-ALPHA, PAS domain-containing protein 8, PASD8alpha subunit (basic helix-loop-helix transcriptionfactor)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
E. coli -derived recombinant human HIF-1 alpha , Arg575-Asn826, Accession # Q16665.1
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种活性 :
人类, 小鼠, 大鼠
特异性 :
Detects human, mouse and rat HIF-1 alpha .
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
基因符号 :
缺氧诱导因子1A
靶标 :
HIF-1甲
AccessionNumbers :
Q16665.1
应用 :
Western Blot, Simple Western, Immunoprecipitation, Chromatin Immunoprecipitation (ChIP), Immunocytochemistry, Knockout Validated
美元 :
375美元
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.