产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
LDLR抗体
目录 :
AF2148
规格 :
100 ug (also 25 ug)
价格 :
464美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 2b
Susan Resiga D, Girard E, Essalmani R, Roubtsova A, Marcinkiewicz J, Derbali R, et al. Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin. J Biol Chem. 2021;297:101177 pubmed 出版商
Levine J, Oleaga C, Eren M, Amaral A, Shang M, Lux E, et al. Role of PAI-1 in hepatic steatosis and dyslipidemia. Sci Rep. 2021;11:430 pubmed 出版商
Huang L, Chambliss K, Gao X, Yuhanna I, Behling Kelly E, Bergaya S, et al. SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis. Nature. 2019;569:565-569 pubmed 出版商
Sachan V, Lodge R, Mihara K, Hamelin J, Power C, Gelman B, et al. HIV-induced neuroinflammation: impact of PAR1 and PAR2 processing by Furin. Cell Death Differ. 2019;: pubmed 出版商
Volkmar N, Thezenas M, Louie S, Juszkiewicz S, Nomura D, Hegde R, et al. The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis. J Cell Sci. 2019;132: pubmed 出版商
Grin P, Dwivedi D, Chathely K, Trigatti B, Prat A, Seidah N, et al. Low-density lipoprotein (LDL)-dependent uptake of Gram-positive lipoteichoic acid and Gram-negative lipopolysaccharide occurs through LDL receptor. Sci Rep. 2018;8:10496 pubmed 出版商
Li X, Guo J, Liang N, Jiang X, Song Y, Ou S, et al. 6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells. Front Pharmacol. 2018;9:159 pubmed 出版商
Liang X, Sun H, Shen W, Wang S, Yao J, Migawa M, et al. Antisense oligonucleotides targeting translation inhibitory elements in 5' UTRs can selectively increase protein levels. Nucleic Acids Res. 2017;45:9528-9546 pubmed 出版商
Felt S, Droby G, Grdzelishvili V. Ruxolitinib and Polycation Combination Treatment Overcomes Multiple Mechanisms of Resistance of Pancreatic Cancer Cells to Oncolytic Vesicular Stomatitis Virus. J Virol. 2017;91: pubmed 出版商
Velázquez Moctezuma R, Law M, Bukh J, Prentoe J. Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A. PLoS Pathog. 2017;13:e1006214 pubmed 出版商
Susan Resiga D, Girard E, Kiss R, Essalmani R, Hamelin J, Asselin M, et al. The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA. J Biol Chem. 2017;292:1573-1590 pubmed 出版商
Fan J, Zareyan S, Zhao W, Shimizu Y, Pfeifer T, Tak J, et al. Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes. PLoS ONE. 2016;11:e0162384 pubmed 出版商
Weider E, Susan Resiga D, Essalmani R, Hamelin J, Asselin M, Nimesh S, et al. Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation. J Biol Chem. 2016;291:16659-71 pubmed 出版商
Ramanathan A, Gusarova V, Stahl N, Gurnett Bander A, Kyratsous C. Alirocumab, a Therapeutic Human Antibody to PCSK9, Does Not Affect CD81 Levels or Hepatitis C Virus Entry and Replication into Hepatocytes. PLoS ONE. 2016;11:e0154498 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF2148 图像 1
LDL R antibody in HepG2 Human Cell Line by Immunocytochemistry (ICC).
产品信息
品牌 :
R&D Systems
master code :
AF2148
SKU号 :
AF2148
产品名称 :
LDLR抗体
描述 :
The Human LDLR Antibody from R&D Systems is a goat polyclonal antibody to LDLR. This antibody reacts with human. The Human LDLR Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Blockade of Receptor-ligand Interaction, Immunocytochemistry.
靶标 :
LDLR
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Chinese hamster ovary cell line CHO-derived recombinant human LDL R, Asp193-Arg788, Accession # P01130
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
人类
特异性 :
Detects human LDL R in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant mouse LDL R is observed.
基因符号 :
LDLR
accessionNumbers :
P01130
应用 :
Western Blot, Immunohistochemistry, Blockade of Receptor-ligand Interaction, Immunocytochemistry
美元 :
464美元
别名 :
FH, FHC, LDL R, LDL receptor, LDLCQ2, low density lipoprotein receptor, low-density lipoprotein receptor, low-density lipoprotein receptor class A domain-containing protein 3
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.