产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
Human Progranulin/PGRN Antibody
目录 :
AF2420-SP
规格 :
25微克
价格 :
135美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 7
参考文献
Frew J, Nygaard H. Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun. 2021;9:57 pubmed 出版商
Berger K, Rhost S, Rafnsdóttir S, Hughes E, Magnusson Y, Ekholm M, et al. Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancer. BMC Cancer. 2021;21:185 pubmed 出版商
Frew J, Baradaran Heravi A, Balgi A, Wu X, Yan T, Arns S, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020;15:21 pubmed 出版商
Mendsaikhan A, Tooyama I, Bellier J, Serrano G, Sue L, Lue L, et al. Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology. Acta Neuropathol Commun. 2019;7:215 pubmed 出版商
Nicholson A, Zhou X, Perkerson R, Parsons T, Chew J, Brooks M, et al. Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity. Acta Neuropathol Commun. 2018;6:42 pubmed 出版商
Zhou X, Paushter D, Feng T, Sun L, Reinheckel T, Hu F. Lysosomal processing of progranulin. Mol Neurodegener. 2017;12:62 pubmed 出版商
Lee C, Stankowski J, Chew J, Cook C, Lam Y, Almeida S, et al. The lysosomal protein cathepsin L is a progranulin protease. Mol Neurodegener. 2017;12:55 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF2420-SP 图像 1
Detection of Human Progranulin/PGRN antibody by Western Blot.
产品信息
品牌 :
R&D Systems
master code :
AF2420
SKU号 :
AF2420-SP
产品名称 :
Human Progranulin/PGRN Antibody
描述 :
The Human Progranulin/PGRN Antibody from R&D Systems is a goat polyclonal antibody to Progranulin/PGRN. This antibody reacts with human. The Human Progranulin/PGRN Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Knockout Validated.
靶标 :
Progranulin/PGRN
类别 :
一抗
单位尺寸 :
25微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant human Progranulin/PGRN, Thr18-Leu593, Accession # P28799
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
人类
特异性 :
Detects human Progranulin/PGRN in direct ELISAs and Western blots.
基因符号 :
GRN
accessionNumbers :
P28799
应用 :
免疫印迹, 免疫组化, 基因敲除验证
美元2021 :
129
美元2022 :
135美元
别名 :
Acrogranin, CLN11, GEP, GP88, granulin precursor, GRN, PCDGF, PEPI, PGRN, Proepithelin
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.