产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
VEGFR2/KDR/Flk-1 Antibody
目录 :
AF644
规格 :
100 ug (also 25 ug)
价格 :
489美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 中和反应, 流式细胞仪, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, proximity ligation assay, 免疫组化基因敲除验证
更多信息或购买 :
文章摘录数: 37
出版应用/物种/样本/稀释参考文献
  • proximity ligation assay; 小鼠; 1:50; 图 3a
Harde E, Nicholson L, Furones Cuadrado B, Bissen D, Wigge S, Urban S, et al. EphrinB2 regulates VEGFR2 during dendritogenesis and hippocampal circuitry development. elife. 2019;8: pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 7j
Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed 出版商
  • proximity ligation assay; 人类; 1:80; 图 2b
Segarra M, Aburto M, Cop F, Llaó Cid C, Härtl R, Damm M, et al. Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science. 2018;361: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 s4a
Thion M, Low D, Silvin A, Chen J, Grisel P, Schulte Schrepping J, et al. Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner. Cell. 2018;172:500-516.e16 pubmed 出版商
  • 免疫组化基因敲除验证; 小鼠; 图 s3c
  • 免疫组化-冰冻切片; 小鼠; 图 s3c
Kim J, Park D, Bae H, Park D, Kim D, Lee C, et al. Impaired angiopoietin/Tie2 signaling compromises Schlemm's canal integrity and induces glaucoma. J Clin Invest. 2017;127:3877-3896 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:50; 图 s2d
Hirai M, Arita Y, McGlade C, Lee K, Chen J, Evans S. Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017;127:569-582 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1b
Wang X, Chen D, Chen K, Jubran A, Ramirez A, Astrof S. Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. Dev Biol. 2017;421:108-117 pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 图 5c
Lucitti J, Sealock R, Buckley B, Zhang H, Xiao L, Dudley A, et al. Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016;47:3022-3031 pubmed
  • 免疫组化-冰冻切片; 小鼠; 图 3p
Huang J, Woolf A, Kolatsi Joannou M, Baluk P, Sandford R, Peters D, et al. Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases. J Am Soc Nephrol. 2016;27:69-77 pubmed 出版商
Jannaway M, Iyer D, Mastrogiacomo D, Li K, Sung D, Yang Y, et al. VEGFR3 is required for button junction formation in lymphatic vessels. Cell Rep. 2023;42:112777 pubmed 出版商
Mueller Diesing F, Lederle W, Rix A, Koletnik S, Doleschel D, Snelting M, et al. Molecular Ultrasound Imaging Depicts the Modulation of Tumor Angiogenesis by Acetylsalicylic Acid. Int J Mol Sci. 2023;24: pubmed 出版商
Lee E, Lee E, Kong E, Chon H, Llaiqui Condori M, Park C, et al. An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone. Exp Mol Med. 2023;55:470-484 pubmed 出版商
Arpino J, Yin H, Prescott E, Staples S, Nong Z, Li F, et al. Low-flow intussusception and metastable VEGFR2 signaling launch angiogenesis in ischemic muscle. Sci Adv. 2021;7:eabg9509 pubmed 出版商
Progatzky F, Shapiro M, Chng S, García Cassani B, Classon C, Sevgi S, et al. Regulation of intestinal immunity and tissue repair by enteric glia. Nature. 2021;599:125-130 pubmed 出版商
Yeom D, Lee Y, Ryu I, Lee S, Sung B, Lee H, et al. ABL001, a Bispecific Antibody Targeting VEGF and DLL4, with Chemotherapy, Synergistically Inhibits Tumor Progression in Xenograft Models. Int J Mol Sci. 2020;22: pubmed 出版商
Hong S, Yang M, Cho H, Park I, Bae H, Choe K, et al. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi. Nat Commun. 2020;11:4102 pubmed 出版商
Su L, Lei X, Ma H, Feng C, Jiang J, Jiao J. PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain. Cell Death Differ. 2020;27:2313-2329 pubmed 出版商
Duc D, Vigne S, Bernier Latmani J, Yersin Y, Ruiz F, Gaïa N, et al. Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis. Cell Rep. 2019;29:378-390.e4 pubmed 出版商
Hendrikx S, Coso S, Prat Luri B, Wetterwald L, Sabine A, Franco C, et al. Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2. Cell Rep. 2019;26:1227-1241.e6 pubmed 出版商
Choquet C, Nguyen T, Sicard P, Buttigieg E, Tran T, Kober F, et al. Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy. PLoS Genet. 2018;14:e1007502 pubmed 出版商
Su T, Stanley G, Sinha R, D Amato G, Das S, Rhee S, et al. Single-cell analysis of early progenitor cells that build coronary arteries. Nature. 2018;559:356-362 pubmed 出版商
Rosin J, Kurrasch D. In utero electroporation induces cell death and alters embryonic microglia morphology and expression signatures in the developing hypothalamus. J Neuroinflammation. 2018;15:181 pubmed 出版商
Kim I, Kim K, Lee E, Oh D, Park C, Park S, et al. Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality. J Exp Med. 2018;215:963-983 pubmed 出版商
Rhee S, Chung J, King D, D Amato G, Paik D, Duan A, et al. Endothelial deletion of Ino80 disrupts coronary angiogenesis and causes congenital heart disease. Nat Commun. 2018;9:368 pubmed 出版商
Drummond C, Hanna J, Garcia M, Devine D, Heyrana A, Finkelstein D, et al. Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors. Cancer Cell. 2018;33:108-124.e5 pubmed 出版商
Sones J, Merriam A, Seffens A, Brown Grant D, Butler S, Zhao A, et al. Angiogenic factor imbalance precedes complement deposition in placentae of the BPH/5 model of preeclampsia. FASEB J. 2017;: pubmed 出版商
Chen Y, Xu H, Lin G. Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse. Cell Discov. 2017;3:17046 pubmed 出版商
Chang A, Raftrey B, D Amato G, Surya V, Poduri A, Chen H, et al. DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017;31:1308-1324 pubmed 出版商
Wu H, Zhao J, Fu B, Yin S, Song C, Zhang J, et al. Retinoic acid-induced upregulation of miR-219 promotes the differentiation of embryonic stem cells into neural cells. Cell Death Dis. 2017;8:e2953 pubmed 出版商
Heinolainen K, Karaman S, D Amico G, Tammela T, Sormunen R, Eklund L, et al. VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling. Circ Res. 2017;120:1414-1425 pubmed 出版商
Langen U, Pitulescu M, Kim J, Enriquez Gasca R, Sivaraj K, Kusumbe A, et al. Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017;19:189-201 pubmed 出版商
Ulvmar M, Martínez Corral I, Stanczuk L, Makinen T. Pdgfrb-Cre targets lymphatic endothelial cells of both venous and non-venous origins. Genesis. 2016;54:350-8 pubmed 出版商
Plein A, Calmont A, Fantin A, Denti L, Anderson N, Scambler P, et al. Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation. J Clin Invest. 2015;125:2661-76 pubmed 出版商
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产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
AF644
SKU号 :
AF644
产品名称 :
VEGFR2/KDR/Flk-1 Antibody
描述 :
The Mouse VEGFR2/KDR/Flk-1 Antibody from R&D Systems is a goat polyclonal antibody to VEGFR2/KDR/Flk-1. This antibody reacts with mouse. The Mouse VEGFR2/KDR/Flk-1 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Neutralization, CyTOF-ready.
靶标 :
VEGFR2/KDR/Flk-1
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant mouse VEGFR2, Ala20-Glu762, Accession # P35918
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
小鼠
特异性 :
Detects mouse VEGFR2 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human VEGFR2 is observed and less than 2% cross-reactivity with recombinant mouse (rm) VEGFR1 and rmVEGFR3 is observed.
基因符号 :
激酶插入区受体
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P35918
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Neutralization, CyTOF-ready
美元 :
489美元
别名 :
CD309, CD309 antigen, EC 2.7.10, EC 2.7.10.1, Fetal liver kinase 1, fetal liver kinase-1, Flk1, Flk-1, FLK1tyrosine kinase growth factor receptor, KDR, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), KRD1, Ly73, Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGF R2, VEGFR, VEGFR2, VEGFR-2
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.