产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
骨桥蛋白/OPN抗体
目录 :
AF808
规格 :
100 ug (also 25 ug)
价格 :
464美元
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应
更多信息或购买 :
文章摘录数: 83
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:100
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Lee S, Park Y, Paik S, Kim I. Differential Response of Müller Cells and Microglia in a Mouse Retinal Detachment Model and Its Implications in Detached and Non-Detached Regions. Cells. 2021;10: pubmed 出版商
Cordero Espinoza L, Dowbaj A, Kohler T, Strauss B, Sarlidou O, Belenguer G, et al. Dynamic cell contacts between periportal mesenchyme and ductal epithelium act as a rheostat for liver cell proliferation. Cell Stem Cell. 2021;28:1907-1921.e8 pubmed 出版商
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Lu C, Liu Z, Klement J, Yang D, Merting A, Poschel D, et al. WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape. J Immunother Cancer. 2021;9: pubmed 出版商
Jan T, Eltawil Y, Ling A, Chen L, Ellwanger D, Heller S, et al. Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics. Cell Rep. 2021;36:109358 pubmed 出版商
Sivaraj K, Jeong H, Dharmalingam B, Zeuschner D, Adams S, Potente M, et al. Regional specialization and fate specification of bone stromal cells in skeletal development. Cell Rep. 2021;36:109352 pubmed 出版商
Yuan Q, Gu J, Zhang J, Liu S, Wang Q, Tian T, et al. MyD88 in myofibroblasts enhances colitis-associated tumorigenesis via promoting macrophage M2 polarization. Cell Rep. 2021;34:108724 pubmed 出版商
Yu L, Zheng Y, Liu B, Kang M, Millar J, Rhee D. Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facility. PLoS ONE. 2020;15:e0241294 pubmed 出版商
Li Y, He X, Kawaguchi R, Zhang Y, Wang Q, Monavarfeshani A, et al. Microglia-organized scar-free spinal cord repair in neonatal mice. Nature. 2020;587:613-618 pubmed 出版商
Christodoulou Vafeiadou E, Geka C, Ntari L, Kranidioti K, Argyropoulou E, Meier F, et al. Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis. Arthritis Res Ther. 2020;22:232 pubmed 出版商
Mahmud F, Du Y, Greif E, Boucher T, Dannals R, Mathews W, et al. Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection. J Neuroinflammation. 2020;17:273 pubmed 出版商
Filiberti A, Gmyrek G, Montgomery M, Sallack R, Carr D. Loss of Osteopontin Expression Reduces HSV-1-Induced Corneal Opacity. Invest Ophthalmol Vis Sci. 2020;61:24 pubmed 出版商
Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed 出版商
Xu T, Lu Z, Xiao Z, Liu F, Chen Y, Wang Z, et al. Myofibroblast induces hepatocyte-to-ductal metaplasia via laminin-ɑvβ6 integrin in liver fibrosis. Cell Death Dis. 2020;11:199 pubmed 出版商
Song J, Pineault K, Dones J, Raines R, Wellik D. Hox genes maintain critical roles in the adult skeleton. Proc Natl Acad Sci U S A. 2020;117:7296-7304 pubmed 出版商
Kole C, Brommer B, Nakaya N, Sengupta M, Bonet Ponce L, Zhao T, et al. Activating Transcription Factor 3 (ATF3) Protects Retinal Ganglion Cells and Promotes Functional Preservation After Optic Nerve Crush. Invest Ophthalmol Vis Sci. 2020;61:31 pubmed 出版商
Fu D, Wang L, Chouairi F, Rose I, Abetov D, Miller A, et al. Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5-CD44+ cells. Nat Commun. 2020;11:84 pubmed 出版商
Feng D, Ngov C, Henley N, Boufaied N, Gerarduzzi C. Characterization of Matricellular Protein Expression Signatures in Mechanistically Diverse Mouse Models of Kidney Injury. Sci Rep. 2019;9:16736 pubmed 出版商
Dong J, Ma Q. In Vivo Activation and Pro-Fibrotic Function of NF-κB in Fibroblastic Cells During Pulmonary Inflammation and Fibrosis Induced by Carbon Nanotubes. Front Pharmacol. 2019;10:1140 pubmed 出版商
Zhang H, Liao M, Cao M, Qiu Z, Yan X, Zhou Y, et al. ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms. J Am Heart Assoc. 2019;8:e012341 pubmed 出版商
Honda S, Namekata K, Kimura A, Guo X, Harada C, Murakami A, et al. Survival of Alpha and Intrinsically Photosensitive Retinal Ganglion Cells in NMDA-Induced Neurotoxicity and a Mouse Model of Normal Tension Glaucoma. Invest Ophthalmol Vis Sci. 2019;60:3696-3707 pubmed 出版商
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Sayyid Z, Wang T, Chen L, Jones S, Cheng A. Atoh1 Directs Regeneration and Functional Recovery of the Mature Mouse Vestibular System. Cell Rep. 2019;28:312-324.e4 pubmed 出版商
Quilichini E, Fabre M, Dirami T, Stedman A, De Vas M, Ozguc O, et al. Pancreatic ductal deletion of Hnf1b disrupts exocrine homeostasis, leads to pancreatitis and facilitates tumorigenesis. Cell Mol Gastroenterol Hepatol. 2019;: pubmed 出版商
Pepe Mooney B, Dill M, Alemany A, Ordovas Montanes J, Matsushita Y, Rao A, et al. Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. Cell Stem Cell. 2019;: pubmed 出版商
Romeo S, Alawi K, Rodrigues J, Singh A, Kusumbe A, Ramasamy S. Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation. Nat Cell Biol. 2019;21:430-441 pubmed 出版商
Hu H, Liu Z, Liu C. Correlation of OPN gene expression with proliferation and apoptosis of ovarian cancer cells and prognosis of patients. Oncol Lett. 2019;17:2788-2794 pubmed 出版商
Caglayan E, Trappiel M, Behringer A, Berghausen E, Odenthal M, Wellnhofer E, et al. Pulmonary arterial remodelling by deficiency of peroxisome proliferator-activated receptor-γ in murine vascular smooth muscle cells occurs independently of obesity-related pulmonary hypertension. Respir Res. 2019;20:42 pubmed 出版商
Wasgewatte Wijesinghe D, Mackie E, Pagel C. Normal inflammation and regeneration of muscle following injury require osteopontin from both muscle and non-muscle cells. Skelet Muscle. 2019;9:6 pubmed 出版商
Giraud E, Rouault E, Fiette L, Colle J, Smirlis D, Melanitou E. Osteopontin in the host response to Leishmania amazonensis. BMC Microbiol. 2019;19:32 pubmed 出版商
Zhao M, Tao F, Venkatraman A, Li Z, Smith S, Unruh J, et al. N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells. Cell Rep. 2019;26:652-669.e6 pubmed 出版商
Kaylan K, Berg I, Biehl M, Brougham Cook A, Jain I, Jamil S, et al. Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling. elife. 2018;7: pubmed 出版商
Wang L, Niu N, Li L, Shao R, Ouyang H, Zou W. H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells. PLoS Biol. 2018;16:e2006522 pubmed 出版商
Lee M, Hwang H, Oh S, Roshanzadeh A, Kim J, Song J, et al. Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression. Exp Mol Med. 2018;50:142 pubmed 出版商
Dhande O, Stafford B, Franke K, El Danaf R, Percival K, Phan A, et al. Molecular Fingerprinting of On-Off Direction-Selective Retinal Ganglion Cells Across Species and Relevance to Primate Visual Circuits. J Neurosci. 2019;39:78-95 pubmed 出版商
Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed 出版商
Jin Y, Cong Q, Gvozdenovic Jeremic J, Hu J, Zhang Y, Terkeltaub R, et al. Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling. Development. 2018;145: pubmed 出版商
D Souza A, Jiang Y, Cast A, Valanejad L, Wright M, Lewis K, et al. Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte Proliferation. Cell Mol Gastroenterol Hepatol. 2018;6:239-255 pubmed 出版商
Himburg H, Termini C, Schlussel L, Kan J, Li M, Zhao L, et al. Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration. Cell Stem Cell. 2018;23:370-381.e5 pubmed 出版商
Zeng Q, Luo X, Han M, Liu W, Li H. Leptin/Osteopontin Axis Regulated Type 2T Helper Cell Response in Allergic Rhinitis with Obesity. EBioMedicine. 2018;32:43-49 pubmed 出版商
Wen Y, Wang C, Gu J, Yu C, Wang K, Sun X, et al. Metabolic modulation of acetaminophen-induced hepatotoxicity by osteopontin. Cell Mol Immunol. 2019;16:483-494 pubmed 出版商
Kim K, Kim S, Han D, Jo Y, Lee Y, Lee M. Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. Sci Rep. 2018;8:6789 pubmed 出版商
Liu J, Reggiani J, Laboulaye M, Pandey S, Chen B, Rubenstein J, et al. Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. Nat Neurosci. 2018;21:659-670 pubmed 出版商
Ding W, Yousefi K, Goncalves S, Goldstein B, Sabater A, Kloosterboer A, et al. Osteopontin deficiency ameliorates Alport pathology by preventing tubular metabolic deficits. JCI Insight. 2018;3: pubmed 出版商
Kobori T, Hamasaki S, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, et al. Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis. Front Immunol. 2018;9:334 pubmed 出版商
Hernandez C, Huebener P, Pradere J, Antoine D, Friedman R, Schwabe R. HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis. J Clin Invest. 2018;128:2436-2451 pubmed 出版商
Hayes K, Messina L, Schwartz L, Yan J, Burnside A, Witkowski S. Type 2 diabetes impairs the ability of skeletal muscle pericytes to augment postischemic neovascularization in db/db mice. Am J Physiol Cell Physiol. 2018;314:C534-C544 pubmed 出版商
Hulsmans M, Sager H, Roh J, Valero Muñoz M, Houstis N, Iwamoto Y, et al. Cardiac macrophages promote diastolic dysfunction. J Exp Med. 2018;215:423-440 pubmed 出版商
Coutu D, Kokkaliaris K, Kunz L, Schroeder T. Multicolor quantitative confocal imaging cytometry. Nat Methods. 2018;15:39-46 pubmed 出版商
de Souza V, Pereira T, Teixeira V, Carvalho H, de Castro M, D assunção C, et al. Bone marrow-derived monocyte infusion improves hepatic fibrosis by decreasing osteopontin, TGF-β1, IL-13 and oxidative stress. World J Gastroenterol. 2017;23:5146-5157 pubmed 出版商
Krieger B, Qiao M, Rousso D, Sanes J, Meister M. Four alpha ganglion cell types in mouse retina: Function, structure, and molecular signatures. PLoS ONE. 2017;12:e0180091 pubmed 出版商
Norsworthy M, Bei F, Kawaguchi R, Wang Q, Tran N, Li Y, et al. Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others. Neuron. 2017;94:1112-1120.e4 pubmed 出版商
Hosaka K, Rojas K, Fazal H, Schneider M, Shores J, Federico V, et al. Monocyte Chemotactic Protein-1-Interleukin-6-Osteopontin Pathway of Intra-Aneurysmal Tissue Healing. Stroke. 2017;48:1052-1060 pubmed 出版商
Guidi N, Sacma M, Ständker L, Soller K, Marka G, Eiwen K, et al. Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells. EMBO J. 2017;36:840-853 pubmed 出版商
Langen U, Pitulescu M, Kim J, Enriquez Gasca R, Sivaraj K, Kusumbe A, et al. Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017;19:189-201 pubmed 出版商
Yuan G, Chen L, Feng J, Yang G, Ni Q, Xu X, et al. Dentin Sialoprotein is a Novel Substrate of Matrix Metalloproteinase 9 in vitro and in vivo. Sci Rep. 2017;7:42449 pubmed 出版商
Chen C, Sue Y, Cheng C, Chen Y, Liu C, Hsu Y, et al. Oligo-fucoidan prevents renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway. Sci Rep. 2017;7:40183 pubmed 出版商
Hammers D, Sleeper M, Forbes S, Coker C, Jirousek M, Zimmer M, et al. Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle. JCI Insight. 2016;1:e90341 pubmed 出版商
Morisaki Y, Niikura M, Watanabe M, Onishi K, Tanabe S, Moriwaki Y, et al. Selective Expression of Osteopontin in ALS-resistant Motor Neurons is a Critical Determinant of Late Phase Neurodegeneration Mediated by Matrix Metalloproteinase-9. Sci Rep. 2016;6:27354 pubmed 出版商
Ozaki T, Muramatsu R, Sasai M, Yamamoto M, Kubota Y, Fujinaka T, et al. The P2X4 receptor is required for neuroprotection via ischemic preconditioning. Sci Rep. 2016;6:25893 pubmed 出版商
Shiraishi M, Shintani Y, Shintani Y, Ishida H, Saba R, Yamaguchi A, et al. Alternatively activated macrophages determine repair of the infarcted adult murine heart. J Clin Invest. 2016;126:2151-66 pubmed 出版商
Zhao K, Zhang M, Zhang L, Wang P, Song G, Liu B, et al. Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response. Sci Rep. 2016;6:23771 pubmed 出版商
Wirsdörfer F, de Leve S, Cappuccini F, Eldh T, Meyer A, Gau E, et al. Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis. Cancer Res. 2016;76:3045-56 pubmed 出版商
Friedmann Morvinski D, Bhargava V, Gupta S, Verma I, Subramaniam S. Identification of therapeutic targets for glioblastoma by network analysis. Oncogene. 2016;35:608-20 pubmed 出版商
图像
图像 1 :
安迪生物R&D AF808 图像 1
Osteopontin/OPN antibody in C2C12 Mouse Cell Line and Mouse Splenocytes by Immunocytochemistry (ICC).
产品信息
品牌 :
R&D Systems
master code :
AF808
SKU号 :
AF808
产品名称 :
骨桥蛋白/OPN抗体
描述 :
The Mouse Osteopontin/OPN Antibody from R&D Systems is a goat polyclonal antibody to Osteopontin/OPN. This antibody reacts with mouse. The Mouse Osteopontin/OPN Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Neutralization, Immunocytochemistry, ELISA Capture (Matched Antibody Pair).
靶标 :
骨桥蛋白/OPN
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
多克隆
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
山羊
免疫原 :
Mouse myeloma cell line NS0-derived recombinant mouse Osteopontin/OPN (R D Systems, Catalog # 441-OP), Leu17-Asn294 (Glu99Gly), Accession # Q547B5
抗体亚型 :
IgG
纯度 :
抗原亲和纯化
物种 :
小鼠
特异性 :
Detects mouse Osteopontin (OPN) in ELISAs and Western blots.
基因符号 :
SPP1
内毒素说明 :
<0.30 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
Q547B5
应用 :
Western Blot, Immunohistochemistry, Neutralization, Immunocytochemistry, ELISA Capture (Matched Antibody Pair)
美元 :
464美元
别名 :
BNSP, Bone sialoprotein 1, Eta-1, MGC110940, Nephropontin, OPN, osteopontin, secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1), secreted phosphoprotein-1 (osteopontin, bone sialoprotein), Spp1, SPP-1, SPP1/CALPHA1 fusion, Urinary stone protein, uropontin
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.