产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
CD44 v6抗体
目录 :
BBA13
规格 :
200微克
价格 :
464美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2F10
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 23
参考文献
Di Franco S, Bianca P, Sardina D, Turdo A, Gaggianesi M, Veschi V, et al. Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery. Nat Commun. 2021;12:5006 pubmed 出版商
Manic G, Musella M, Corradi F, Sistigu A, Vitale S, Soliman Abdel Rehim S, et al. Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51. Cell Death Differ. 2021;28:2060-2082 pubmed 出版商
Hu S, Cao M, He Y, Zhang G, Liu Y, Du Y, et al. CD44v6 Targeted by miR-193b-5p in the Coding Region Modulates the Migration and Invasion of Breast Cancer Cells. J Cancer. 2020;11:260-271 pubmed 出版商
Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed 出版商
Wang D, Fu L, Wei J, Xiong Y, DuBois R. PPARδ Mediates the Effect of Dietary Fat in Promoting Colorectal Cancer Metastasis. Cancer Res. 2019;79:4480-4490 pubmed 出版商
Giampieri R, Piva F, Occhipinti G, Bittoni A, Righetti A, Pagliaretta S, et al. Clinical impact of different exosomes' protein expression in pancreatic ductal carcinoma patients treated with standard first line palliative chemotherapy. PLoS ONE. 2019;14:e0215990 pubmed 出版商
Tirella A, Kloc Muniak K, Good L, Ridden J, Ashford M, Puri S, et al. CD44 targeted delivery of siRNA by using HA-decorated nanotechnologies for KRAS silencing in cancer treatment. Int J Pharm. 2019;561:114-123 pubmed 出版商
Navas T, Pfister T, Colantonio S, Aziz A, Dieckman L, Saul R, et al. Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells. PLoS ONE. 2018;13:e0199361 pubmed 出版商
Chiou G, Yang T, Huang C, Tang C, Yen J, Tsai M, et al. Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells. Sci Rep. 2017;7:2172 pubmed 出版商
Whelan K, Chandramouleeswaran P, Tanaka K, Natsuizaka M, Guha M, Srinivasan S, et al. Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance. Oncogene. 2017;36:4843-4858 pubmed 出版商
Hanke Roos M, Fuchs K, Maleschlijski S, Sleeman J, Orian Rousseau V, Rosenhahn A. CD44 mediates the catch-bond activated rolling of HEPG2Iso epithelial cancer cells on hyaluronan. Cell Adh Migr. 2017;11:476-487 pubmed 出版商
Yoo S, Leng L, Kim B, Du X, Tilstam P, Kim K, et al. MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2016;113:E7917-E7926 pubmed
Teye K, Numata S, Ishii N, Krol R, Tsuchisaka A, Hamada T, et al. Isolation of All CD44 Transcripts in Human Epidermis and Regulation of Their Expression by Various Agents. PLoS ONE. 2016;11:e0160952 pubmed 出版商
Eom B, Joo J, Park B, Jo M, Choi S, Cho S, et al. Nomogram Incorporating CD44v6 and Clinicopathological Factors to Predict Lymph Node Metastasis for Early Gastric Cancer. PLoS ONE. 2016;11:e0159424 pubmed 出版商
Francescangeli F, Contavalli P, de Angelis M, Baiocchi M, Gambara G, Pagliuca A, et al. Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer. Cell Death Differ. 2015;22:1700-13 pubmed 出版商
Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed 出版商
Rowehl R, Burke S, Bialkowska A, Pettet D, Rowehl L, Li E, et al. Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. PLoS ONE. 2014;9:e99091 pubmed 出版商
Rizzardi A, Rosener N, Koopmeiners J, Isaksson Vogel R, Metzger G, Forster C, et al. Evaluation of protein biomarkers of prostate cancer aggressiveness. BMC Cancer. 2014;14:244 pubmed 出版商
Todaro M, Gaggianesi M, Catalano V, Benfante A, Iovino F, Biffoni M, et al. CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis. Cell Stem Cell. 2014;14:342-56 pubmed 出版商
Baccelli I, Schneeweiss A, Riethdorf S, Stenzinger A, Schillert A, Vogel V, et al. Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay. Nat Biotechnol. 2013;31:539-44 pubmed 出版商
Barbour A, Reeder J, Walsh M, Fawcett J, Antalis T, Gotley D. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3. Cancer Res. 2003;63:887-92 pubmed
Herrera Gayol A, Jothy S. Effect of hyaluronan on xenotransplanted breast cancer. Exp Mol Pathol. 2002;72:179-85 pubmed
Dingemans K, Ramkema M, Pals S. CD44 is exposed to the extracellular matrix at invasive sites in basal cell carcinomas. Lab Invest. 2002;82:313-22 pubmed
图像
图像 1 :
安迪生物R&D BBA13 图像 1
Detection of CD44 antibody in Human Blood Monocytes antibody by Flow Cytometry.
产品信息
品牌 :
R&D Systems
master code :
BBA13
SKU号 :
BBA13
产品名称 :
CD44 v6抗体
描述 :
The Human CD44v6 Antibody from R&D Systems is a mouse monoclonal antibody to CD44. This antibody reacts with human. The Human CD44v6 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, CyTOF-ready.
靶标 :
CD44
类别 :
一抗
单位尺寸 :
200微克
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose.
克隆性 :
单克隆
克隆 :
2F10
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
重组人类CD44 v3-10
抗体亚型 :
IgG1
纯度 :
蛋白质A或G纯化来自腹水
物种 :
人类
特异性 :
Detects human CD44v6 in Western blots. By flow cytometry analysis using a panel of CD44-transfected COS cells (9), monoclonal antibody clone 2F10 was deduced to be specific for human CD44 protein isoforms containing variant exon 6 (CD44v6).
基因符号 :
CD44
应用 :
Western Blot, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, CyTOF-ready
美元 :
464美元
别名 :
CD44, CD44 antigen, CD44 molecule (Indian blood group), CD44R, CDw44, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, CSPG8, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HCAM, HCELL, hematopoietic cell E- and L-selectin ligand, Heparan sulfate proteoglycan, Hermes antigen, homing function and Indian blood group system, HUTCH-I, Hyaluronate receptor, IN, LHR, MC56, MDU2, MDU2CD44 antigen (homing function and Indian blood group system), MDU3, MDU3CDW44, MIC4, MIC4MGC10468, MUTCH-I, Pgp1, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.