产品简要
公司名称 :
安迪生物R&D
产品类型 :
蛋白
产品名称 :
Caspase-9 Inhibitor Z-LEHD-FMK
目录 :
FMK008
规格 :
1毫克
价格 :
215美元
更多信息或购买 :
文章摘录数: 63
参考文献
Woznicki J, Saini N, Flood P, Rajaram S, Lee C, Stamou P, et al. TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells. Cell Death Dis. 2021;12:864 pubmed 出版商
Woo K, Kim D, Oh M, Park H, Choi C. N-3-Hydroxy Dodecanoyl-DL-homoserine Lactone (OH-dDHL) Triggers Apoptosis of Bone Marrow-Derived Macrophages through the ER- and Mitochondria-Mediated Pathways. Int J Mol Sci. 2021;22: pubmed 出版商
Kauroo S, Govinden Soulange J, Ranghoo Sanmukhiya V, Miranda K, Cotham W, Walla M, et al. Extracts of select endemic plants from the Republic of Mauritius exhibiting anti-cancer and immunomodulatory properties. Sci Rep. 2021;11:4272 pubmed 出版商
Kratochvilova A, Veselá B, Ledvina V, Svandová E, Kleparnik K, Dadakova K, et al. Osteogenic impact of pro-apoptotic caspase inhibitors in MC3T3-E1 cells. Sci Rep. 2020;10:7489 pubmed 出版商
Khan A, Mohamed E, Hakeem I, Nazeer A, Kuttikrishnan S, Prabhu K, et al. Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species. Molecules. 2020;25: pubmed 出版商
Qadir A, Stults A, Murmann A, Peter M. The mechanism of how CD95/Fas activates the Type I IFN/STAT1 axis, driving cancer stemness in breast cancer. Sci Rep. 2020;10:1310 pubmed 出版商
An H, Chung K, Park H, Hong J, Gim J, Choi H, et al. CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis. Autophagy. 2019;:1-20 pubmed 出版商
Del Gaudio N, Di Costanzo A, Liu N, Conte L, Migliaccio A, Vermeulen M, et al. BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition. Cell Death Dis. 2019;10:338 pubmed 出版商
Giebel A, Hu S, Rajaram K, Finethy R, Toh E, Brothwell J, et al. Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture. MBio. 2019;10: pubmed 出版商
Fujiki K, Inamura H, Sugaya T, Matsuoka M. Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms. Cell Death Differ. 2019;: pubmed 出版商
Ross J, Dungen K, Bressler K, Fredriksen M, Khandige Sharma D, Balasingam N, et al. Eukaryotic initiation factor 5B (eIF5B) provides a critical cell survival switch to glioblastoma cells via regulation of apoptosis. Cell Death Dis. 2019;10:57 pubmed 出版商
Kaminski A, Gupta K, Goldufsky J, Lee H, Gupta V, Shafikhani S. Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity. Sci Rep. 2018;8:14047 pubmed 出版商
Danish L, Imig D, Allgöwer F, Scheurich P, Pollak N. Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps. PLoS ONE. 2018;13:e0198203 pubmed 出版商
Rijal D, Ariana A, Wight A, Kim K, Alturki N, Aamir Z, et al. Differentiated macrophages acquire a pro-inflammatory and cell death-resistant phenotype due to increasing XIAP and p38-mediated inhibition of RipK1. J Biol Chem. 2018;293:11913-11927 pubmed 出版商
Gonzalez Juarbe N, Bradley K, Riegler A, Reyes L, Brissac T, Park S, et al. Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia. Sci Rep. 2018;8:5846 pubmed 出版商
Huang W, Deng H, Jin S, Ma X, Zha K, Xie M. The isolation, structural characterization and anti-osteosarcoma activity of a water soluble polysaccharide from Agrimonia pilosa. Carbohydr Polym. 2018;187:19-25 pubmed 出版商
Vaisman C, del Moral Hernández O, Moreno Campuzano S, Arechaga Ocampo E, Bonilla Moreno R, Garcia Aguiar I, et al. C33-A cells transfected with E6*I or E6*II the short forms of HPV-16 E6, displayed opposite effects on cisplatin-induced apoptosis. Virus Res. 2018;247:94-101 pubmed 出版商
Kim J, Kim J, Roh J, Park C, Seoh J, Hwang E. Reactive oxygen species-induced parthanatos of immunocytes by human cytomegalovirus-associated substance. Microbiol Immunol. 2018;62:229-242 pubmed 出版商
Stammer R, Kleinsimon S, Rolff J, Jäger S, Eggert A, Seifert G, et al. Synergistic Antitumour Properties of viscumTT in Alveolar Rhabdomyosarcoma. J Immunol Res. 2017;2017:4874280 pubmed 出版商
Kim H, Hwang K, Park D, Oh S, Jun H, Yoon K, et al. Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells. J Transl Med. 2017;15:123 pubmed 出版商
Kruger H, Bauer G. Lactobacilli enhance reactive oxygen species-dependent apoptosis-inducing signaling. Redox Biol. 2017;11:715-724 pubmed 出版商
Bielaszewska M, Rüter C, Bauwens A, Greune L, Jarosch K, Steil D, et al. Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell injury. PLoS Pathog. 2017;13:e1006159 pubmed 出版商
You B, Han B, Park W. Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-α through up-regulation of TNF receptor 1 in lung cancer cells. Oncotarget. 2017;8:17726-17737 pubmed 出版商
Xuan W, Zhao H, Hankin J, Chen L, Yao S, Ma D. Local anesthetic bupivacaine induced ovarian and prostate cancer apoptotic cell death and underlying mechanisms in vitro. Sci Rep. 2016;6:26277 pubmed 出版商
Arizmendi O, Picking W, Picking W. Macrophage Apoptosis Triggered by IpaD from Shigella flexneri. Infect Immun. 2016;84:1857-1865 pubmed 出版商
Cheung S, Chuang P, Huang H, Hwang Verslues W, Cho C, Yang W, et al. Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells. Proc Natl Acad Sci U S A. 2016;113:960-5 pubmed 出版商
Callaway J, Smith S, Widman D, McKinnon K, Scholle F, Sempowski G, et al. Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model. PLoS ONE. 2015;10:e0136708 pubmed 出版商
Oskarsson M, Singh K, Wang J, Vlodavsky I, Li J, Westermark G. Heparan Sulfate Proteoglycans Are Important for Islet Amyloid Formation and Islet Amyloid Polypeptide-induced Apoptosis. J Biol Chem. 2015;290:15121-32 pubmed 出版商
Yang Z, Balic A, Michon F, Juuri E, Thesleff I. Mesenchymal Wnt/β-Catenin Signaling Controls Epithelial Stem Cell Homeostasis in Teeth by Inhibiting the Antiapoptotic Effect of Fgf10. Stem Cells. 2015;33:1670-81 pubmed 出版商
Harashima N, Minami T, Uemura H, Harada M. Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon-β-mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system. Mol Cancer. 2014;13:217 pubmed 出版商
Mhaidat N, Bouklihacene M, Thorne R. 5-Fluorouracil-induced apoptosis in colorectal cancer cells is caspase-9-dependent and mediated by activation of protein kinase C-δ. Oncol Lett. 2014;8:699-704 pubmed
Teigler J, Kagan J, Barouch D. Late endosomal trafficking of alternative serotype adenovirus vaccine vectors augments antiviral innate immunity. J Virol. 2014;88:10354-63 pubmed 出版商
Lin J, Lin S, Chen W, Yen Y, Lai C, Tao M, et al. Dengue viral protease interaction with NF-?B inhibitor ?/? results in endothelial cell apoptosis and hemorrhage development. J Immunol. 2014;193:1258-67 pubmed 出版商
Jang J, Kim S, Cho E, Jeong S, Park E, Lee W, et al. TRAIL enhances apoptosis of human hepatocellular carcinoma cells sensitized by hepatitis C virus infection: therapeutic implications. PLoS ONE. 2014;9:e98171 pubmed 出版商
Liu B, Meng D, Wei T, Zhang S, Hu Y, Wang M. Apoptosis and pro-inflammatory cytokine response of mast cells induced by influenza A viruses. PLoS ONE. 2014;9:e100109 pubmed 出版商
Seo H, Ku J, Choi H, Woo J, Jang B, Shin Y, et al. Induction of caspase-dependent apoptosis by apigenin by inhibiting STAT3 signaling in HER2-overexpressing MDA-MB-453 breast cancer cells. Anticancer Res. 2014;34:2869-82 pubmed
Ham S, Kim K, Kwon T, Bak Y, Lee D, Song Y, et al. Luteolin induces intrinsic apoptosis via inhibition of E6/E7 oncogenes and activation of extrinsic and intrinsic signaling pathways in HPV-18-associated cells. Oncol Rep. 2014;31:2683-91 pubmed 出版商
Park W. Anti-apoptotic effect of caspase inhibitors on H?O?-treated HeLa cells through early suppression of its oxidative stress. Oncol Rep. 2014;31:2413-21 pubmed 出版商
You B, Park W. Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels. Int J Oncol. 2014;44:1745-55 pubmed 出版商
Stölting D, Borrmann M, Koch M, Wiese M, Royer H, Bendas G. How liposomal Cisplatin overcomes chemoresistance in ovarian tumour cells. Anticancer Res. 2014;34:525-30 pubmed
Shin H, You B, Park W. PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion. Oncol Lett. 2013;6:1804-1810 pubmed
Wang J, Zheng X, Zeng G, Zhou Y, Yuan H. Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma. Oncol Rep. 2014;31:488-96 pubmed 出版商
You B, Shin H, Park W. PX-12 inhibits the growth of A549 lung cancer cells via G2/M phase arrest and ROS-dependent apoptosis. Int J Oncol. 2014;44:301-8 pubmed 出版商
Chakravarthi B, Sujay R, Kuriakose G, Karande A, Jayabaskaran C. Inhibition of cancer cell proliferation and apoptosis-inducing activity of fungal taxol and its precursor baccatin III purified from endophytic Fusarium solani. Cancer Cell Int. 2013;13:105 pubmed 出版商
Jin Y, Xu J, Yin M, Lu Y, Hu L, Li P, et al. Brahma is essential for Drosophila intestinal stem cell proliferation and regulated by Hippo signaling. elife. 2013;2:e00999 pubmed 出版商
Han B, You B, Park W. Valproic acid inhibits the growth of HeLa cervical cancer cells via caspase-dependent apoptosis. Oncol Rep. 2013;30:2999-3005 pubmed 出版商
Bauer G. HOCl-dependent singlet oxygen and hydroxyl radical generation modulate and induce apoptosis of malignant cells. Anticancer Res. 2013;33:3589-602 pubmed
Magnifico S, Saias L, Deléglise B, Duplus E, Kilinc D, Miquel M, et al. NAD+ acts on mitochondrial SirT3 to prevent axonal caspase activation and axonal degeneration. FASEB J. 2013;27:4712-22 pubmed 出版商
Zhou Y, Tian L, Long L, Quan M, Liu F, Cao J. Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress. PLoS ONE. 2013;8:e58855 pubmed 出版商
Liao Y, Lu C, Lai K, Yang J, Kuo S, Wen Y, et al. The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells. Mol Med Rep. 2013;7:1539-44 pubmed 出版商
Koto K, Murata H, Kimura S, Sawai Y, Horie N, Matsui T, et al. Zoledronic acid significantly enhances radiation?induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling. Int J Oncol. 2013;42:525-34 pubmed 出版商
Chang M, Lo J, Juan H, Chang H, Chuang C. Combination of RGD compound and low-dose paclitaxel induces apoptosis in human glioblastoma cells. PLoS ONE. 2012;7:e37935 pubmed 出版商
Liang X, Moseman E, Farrar M, Bachanova V, Weisdorf D, Blazar B, et al. Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells. Blood. 2010;115:5041-52 pubmed 出版商
Tsai W, Yeow W, Chua A, Reddy R, Nguyen D, Schrump D, et al. Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin. Mol Cancer Ther. 2006;5:2977-90 pubmed
Cao Y, Adhikari S, Ang A, Moore P, Bhatia M. Mechanism of induction of pancreatic acinar cell apoptosis by hydrogen sulfide. Am J Physiol Cell Physiol. 2006;291:C503-10 pubmed
Lee S, Chan J, Clement M, Pervaiz S. Functional proteomics of resveratrol-induced colon cancer cell apoptosis: caspase-6-mediated cleavage of lamin A is a major signaling loop. Proteomics. 2006;6:2386-94 pubmed
Conde de la Rosa L, Schoemaker M, Vrenken T, Buist Homan M, Havinga R, Jansen P, et al. Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases. J Hepatol. 2006;44:918-29 pubmed
Attali G, Gancz D, Fishelson Z. Increased sensitivity of early apoptotic cells to complement-mediated lysis. Eur J Immunol. 2004;34:3236-45 pubmed
Chopin V, Slomianny C, Hondermarck H, Le Bourhis X. Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1). Exp Cell Res. 2004;298:560-73 pubmed
Shah N, Asch R, Lysholm A, Lebien T. Enhancement of stress-induced apoptosis in B-lineage cells by caspase-9 inhibitor. Blood. 2004;104:2873-8 pubmed
Aguzzi M, Giampietri C, De Marchis F, Padula F, Gaeta R, Ragone G, et al. RGDS peptide induces caspase 8 and caspase 9 activation in human endothelial cells. Blood. 2004;103:4180-7 pubmed
Sauerwald T, Oyler G, Betenbaugh M. Study of caspase inhibitors for limiting death in mammalian cell culture. Biotechnol Bioeng. 2003;81:329-40 pubmed
Furukawa Y, Nishimura N, Furukawa Y, Satoh M, Endo H, Iwase S, et al. Apaf-1 is a mediator of E2F-1-induced apoptosis. J Biol Chem. 2002;277:39760-8 pubmed
产品信息
品牌 :
R&D Systems
master code :
FMK008
SKU号 :
FMK008
产品名称 :
Caspase-9 Inhibitor Z-LEHD-FMK
靶标 :
胱氨酸-天冬氨酸蛋白酶9
类别 :
单位尺寸 :
1毫克
物种 :
Multi-Species
美元 :
215美元
别名 :
APAF-3APAF3, apoptotic protease activating factor 3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP9, CASP-9, caspase 9, apoptosis-related cysteine peptidase, caspase-9, Caspase9, EC 3.4.22.62, ICE-LAP6CASPASE-9c, ICE-like apoptotic protease 6, MCH6apoptosis-related cysteine protease
储存 :
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.