产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
IL-12/IL-35 p35抗体
目录 :
MAB1570-100
规格 :
100 ug (also 500 ug, 25 ug)
价格 :
469美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
27537
反应物种 :
人类, 小鼠
应用 :
免疫印迹
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 14
参考文献
Luo Z, Sol xe4 ng C, Larsson R, Singh K. Interleukin-35 Prevents the Elevation of the M1/M2 Ratio of Macrophages in Experimental Type 1 Diabetes. Int J Mol Sci. 2022;23: pubmed 出版商
Wetzel A, Scholtka B, Schumacher F, Rawel H, Geisendörfer B, Kleuser B. Epigenetic DNA Methylation of EBI3 Modulates Human Interleukin-35 Formation via NFkB Signaling: A Promising Therapeutic Option in Ulcerative Colitis. Int J Mol Sci. 2021;22: pubmed 出版商
Mizoguchi I, Ohashi M, Hasegawa H, Chiba Y, Orii N, Inoue S, et al. EBV-induced gene 3 augments IL-23Rα protein expression through a chaperone calnexin. J Clin Invest. 2020;130:6124-6140 pubmed 出版商
Wang L, Zhu S, Xu G, Feng J, Han T, Zhao F, et al. Gene Expression and Antiviral Activity of Interleukin-35 in Response to Influenza A Virus Infection. J Biol Chem. 2016;291:16863-76 pubmed 出版商
Halpert M, Konduri V, Liang D, Chen Y, Wing J, Paust S, et al. Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7. Stem Cells Dev. 2016;25:774-87 pubmed 出版商
Liu G, Bi Y, Xue L, Zhang Y, Yang H, Chen X, et al. Dendritic cell SIRT1-HIF1α axis programs the differentiation of CD4+ T cells through IL-12 and TGF-β1. Proc Natl Acad Sci U S A. 2015;112:E957-65 pubmed 出版商
Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, et al. Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353 pubmed 出版商
Rossetti M, Spreafico R, Saidin S, Chua C, Moshref M, Leong J, et al. Ex vivo-expanded but not in vitro-induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory T cell-specific demethylated region. J Immunol. 2015;194:113-24 pubmed 出版商
Kochetkova I, Thornburg T, Callis G, Holderness K, Maddaloni M, Pascual D. Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27. J Immunol. 2014;192:804-16 pubmed 出版商
Olson B, Jankowska Gan E, Becker J, Vignali D, Burlingham W, McNeel D. Human prostate tumor antigen-specific CD8+ regulatory T cells are inhibited by CTLA-4 or IL-35 blockade. J Immunol. 2012;189:5590-601 pubmed 出版商
Seyerl M, Kirchberger S, Majdic O, Seipelt J, Jindra C, Schrauf C, et al. Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. Eur J Immunol. 2010;40:321-9 pubmed 出版商
Maneechotesuwan K, Wamanuttajinda V, Kasetsinsombat K, Huabprasert S, Yaikwawong M, Barnes P, et al. Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. J Allergy Clin Immunol. 2009;123:239-48 pubmed 出版商
Liu T, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, et al. Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells. Eur J Immunol. 2008;38:1012-23 pubmed 出版商
Nagarajan S, Selvaraj P. Human tumor membrane vesicles modified to express glycolipid-anchored IL-12 by protein transfer induce T cell proliferation in vitro: a potential approach for local delivery of cytokines during vaccination. Vaccine. 2006;24:2264-74 pubmed
产品信息
品牌 :
R&D Systems, a Bio-Techne Brand
catalog number base :
MAB1570
SKU号 :
MAB1570-100
产品名称 :
IL-12/IL-35 p35抗体
描述 :
The Human/Mouse IL-12/IL-35 p35 Antibody from R&D Systems is a mouse monoclonal antibody to IL-12/IL-35 p35. This antibody reacts with human, mouse. The Human/Mouse IL-12/IL-35 p35 Antibody has been validated for the following applications: Western Blot, Intracellular Staining by Flow Cytometry, CyTOF-ready.
靶标 :
IL-12/IL-35 p35
类别 :
一抗
单位尺寸 :
100 ug (also 500 ug, 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
27537
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-12/IL-35 p35, Arg23-Ser219, Accession # P29459
抗体亚型 :
IgG1
纯度 :
蛋白质A或G纯化来自腹水
物种 :
人类, 小鼠
特异性 :
Detects human IL-12/IL-35 p35 in direct ELISAs and Western blots. Detects the p35 subunit either as part of a p40/p35 heterodimer or as a free subunit after reduction of the heterodimer. This antibody does not recognize IL-12 p40 homodimers but shows strong cross-reactivity with the p35 subunits from porcine and mouse systems.
基因符号 :
IL12A
accessionNumbers :
P29459
应用 :
Western Blot, Intracellular Staining by Flow Cytometry, CyTOF-ready
美元 :
469美元
别名 :
CLMF;IL12A;IL-12A;IL-12p35;Ll12a;NFSK;NKSF1;P35, CLMF1, 白细胞介素-12, IL12A, IL-12A, IL35p35, NKSF1
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.