产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
趋化因子受体4抗体
目录 :
MAB173-100
规格 :
100 ug (also 25 ug)
价格 :
442美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
44717
反应物种 :
人类
应用 :
中和反应, 流式细胞仪
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 21
参考文献
Shamshirgaran Y, Jonebring A, Svensson A, Leefa I, Bohlooly Y M, Firth M, et al. Rapid target validation in a Cas9-inducible hiPSC derived kidney model. Sci Rep. 2021;11:16532 pubmed 出版商
Armani Tourret M, Zhou Z, Gasser R, Staropoli I, Cantaloube Ferrieu V, Benureau Y, et al. Mechanisms of HIV-1 evasion to the antiviral activity of chemokine CXCL12 indicate potential links with pathogenesis. PLoS Pathog. 2021;17:e1009526 pubmed 出版商
Subramani P, Vartak Sharma N, Sreekumar S, Mathur P, Nayer B, Dakhore S, et al. Plasmodium vivax liver stage assay platforms using Indian clinical isolates. Malar J. 2020;19:214 pubmed 出版商
Facciotti F, Larghi P, Bosotti R, Vasco C, Gagliani N, Cordiglieri C, et al. Evidence for a pathogenic role of extrafollicular, IL-10-producing CCR6+B helper T cells in systemic lupus erythematosus. Proc Natl Acad Sci U S A. 2020;117:7305-7316 pubmed 出版商
Desplantes R, Leveque C, Müller B, Lotierzo M, Ferracci G, Popoff M, et al. Affinity biosensors using recombinant native membrane proteins displayed on exosomes: application to botulinum neurotoxin B receptor. Sci Rep. 2017;7:1032 pubmed 出版商
Huang K, Kiefer C, Kamal A. Novel role for NFAT3 in ERK-mediated regulation of CXCR4. PLoS ONE. 2014;9:e115249 pubmed 出版商
Carrega P, Bonaccorsi I, Di Carlo E, Morandi B, Paul P, Rizzello V, et al. CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph. J Immunol. 2014;192:3805-15 pubmed 出版商
Kulbe H, Chakravarty P, Leinster D, Charles K, Kwong J, Thompson R, et al. A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment. Cancer Res. 2012;72:66-75 pubmed 出版商
Naumann U, Cameroni E, Pruenster M, Mahabaleshwar H, Raz E, Zerwes H, et al. CXCR7 functions as a scavenger for CXCL12 and CXCL11. PLoS ONE. 2010;5:e9175 pubmed 出版商
Kollmar O, Rupertus K, Scheuer C, Nickels R, Haberl G, Tilton B, et al. CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1. Int J Cancer. 2010;126:1302-15 pubmed 出版商
Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, et al. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J Exp Med. 2009;206:249-58 pubmed 出版商
Hansson M, Hermansson M, Svensson H, Elfvin A, Hansson L, Johnsson E, et al. CCL28 is increased in human Helicobacter pylori-induced gastritis and mediates recruitment of gastric immunoglobulin A-secreting cells. Infect Immun. 2008;76:3304-11 pubmed 出版商
Struckmann K, Mertz K, Steu S, Storz M, Staller P, Krek W, et al. pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma. J Pathol. 2008;214:464-71 pubmed 出版商
Kang S, Lim H, Andrisani O, Broxmeyer H, Kim C. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007;179:3724-33 pubmed
Ponte A, Marais E, Gallay N, Langonne A, Delorme B, Herault O, et al. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities. Stem Cells. 2007;25:1737-45 pubmed
Lim H, Hillsamer P, Kim C. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J Clin Invest. 2004;114:1640-9 pubmed
Curiel T, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-9 pubmed
de Parseval A, Ngo S, Sun P, Elder J. Factors that increase the effective concentration of CXCR4 dictate feline immunodeficiency virus tropism and kinetics of replication. J Virol. 2004;78:9132-43 pubmed 出版商
Hatse S, Princen K, Vermeire K, Gerlach L, Rosenkilde M, Schwartz T, et al. Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry. FEBS Lett. 2003;546:300-6 pubmed
Willett B, Cannon C, Hosie M. Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. J Virol. 2003;77:709-12 pubmed
Nguyen D, Taub D. CXCR4 function requires membrane cholesterol: implications for HIV infection. J Immunol. 2002;168:4121-6 pubmed
图像
图像 1 :
安迪生物R&D MAB173-100 图像 1
Chemotaxis Induced by CXCL12/SDF-1a and Neutralization by Human CXCR4 Antibody.
产品信息
品牌 :
R&D Systems
master code :
MAB173
SKU号 :
MAB173-100
产品名称 :
趋化因子受体4抗体
描述 :
The Human CXCR4 Antibody from R&D Systems is a mouse monoclonal antibody to CXCR4. This antibody reacts with human. The Human CXCR4 Antibody has been validated for the following applications: Flow Cytometry, Neutralization, CyTOF-ready.
靶标 :
趋化因子受体4
类别 :
一抗
sizes available :
100 ug (also 25 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
44717
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
3T3 cells transfected with human CXCR4
抗体亚型 :
IgG2b
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Reacts specifically with human and non-human cells expressing human CXCR4 (fusin) as detected by flow cytometry
基因符号 :
趋化因子受体4
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
应用 :
Flow Cytometry, Neutralization, CyTOF-ready
美元 :
442美元
别名 :
CD184, chemokine (C-X-C motif) receptor 4, chemokine (C-X-C motif), receptor 4 (fusin), C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, D2S201E, D2S201ESDF-1 receptor, FB22, Fusin, HM89, HM89NPYRL, HSY3RR, LAP3, LAP-3, LCR1, LESTR, LESTRCD184 antigen, Leukocyte-derived seven transmembrane domain receptor, leukocyte-derived seven-transmembrane-domain receptor, lipopolysaccharide-associated protein 3, neuropeptide Y receptor Y3, NPY3R, NPY3RWHIM, NPYR, NPYRL, NPYY3R, pCXCR4, seven transmembrane helix receptor, seven-transmembrane-segment receptor, spleen, Stromal cell-derived factor 1 receptor, WHIMS
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.