产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
IL-1乙/IL-1F2抗体
目录 :
MAB201-100
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
453美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
8516
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 中和反应
更多信息或购买 :
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 1:1000; 图 4a
Li Y, Li Y, Li L, Yin M, Wang J, Li X. PKR deficiency alleviates pulmonary hypertension via inducing inflammasome adaptor ASC inactivation. Pulm Circ. 2021;11:20458940211046156 pubmed 出版商
Li Y, Zhu Y, Feng S, Ishida Y, Chiu T, Saito T, et al. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3. Cell Rep. 2022;38:110284 pubmed 出版商
Tsuchiya K, Hosojima S, Hara H, Kushiyama H, Mahib M, Kinoshita T, et al. Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomes. Cell Rep. 2021;34:108887 pubmed 出版商
Abrahams V, Tang Z, Mor G, Guller S. NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cells. J Reprod Immunol. 2020;142:103214 pubmed 出版商
Lichtenegger S, Stiehler J, Saiger S, Zauner A, Kleinhappl B, Bernecker C, et al. Burkholderia pseudomallei triggers canonical inflammasome activation in a human primary macrophage-based infection model. PLoS Negl Trop Dis. 2020;14:e0008840 pubmed 出版商
Israelov H, Ravid O, Atrakchi D, Rand D, Elhaik S, Bresler Y, et al. Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair. J Neuroinflammation. 2020;17:267 pubmed 出版商
Pathak S, Vambutas A. Autoimmune inner ear disease patient-associated 28-kDa proinflammatory IL-1β fragment results from caspase-7-mediated cleavage in vitro. JCI Insight. 2020;5: pubmed 出版商
Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed 出版商
Vogel K, Pierau M, Arra A, Lampe K, Schlueter D, Arens C, et al. Developmental induction of human T-cell responses against Candida albicans and Aspergillus fumigatus. Sci Rep. 2018;8:16904 pubmed 出版商
Clancy D, Sullivan G, Moran H, Henry C, Reeves E, McElvaney N, et al. Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing. Cell Rep. 2018;22:2937-2950 pubmed 出版商
Chambers S, O Neill C, Guduric Fuchs J, McLoughlin K, Liew A, Egan A, et al. The Vasoreparative Function of Myeloid Angiogenic Cells Is Impaired in Diabetes Through the Induction of IL1β. Stem Cells. 2018;36:834-843 pubmed 出版商
Uchino Y, Woodward A, Mauris J, Peterson K, Verma P, Nilsson U, et al. Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytes. Immunology. 2018;154:490-499 pubmed 出版商
Reggiani F, Labanca V, Mancuso P, Rabascio C, Talarico G, Orecchioni S, et al. Adipose Progenitor Cell Secretion of GM-CSF and MMP9 Promotes a Stromal and Immunological Microenvironment That Supports Breast Cancer Progression. Cancer Res. 2017;77:5169-5182 pubmed 出版商
Nishijima N, Hirai T, Misato K, Aoyama M, Kuroda E, Ishii K, et al. Human Scavenger Receptor A1-Mediated Inflammatory Response to Silica Particle Exposure Is Size Specific. Front Immunol. 2017;8:379 pubmed 出版商
Naschberger E, Geißdörfer W, Bogdan C, Tripal P, Kremmer E, Sturzl M, et al. Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity. J Cell Mol Med. 2017;21:1954-1966 pubmed 出版商
Garstkiewicz M, Strittmatter G, Grossi S, Sand J, Fenini G, Werner S, et al. Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression. Eur J Immunol. 2017;47:806-817 pubmed 出版商
Hadadi E, Zhang B, Baidžajevas K, Yusof N, Puan K, Ong S, et al. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability. Sci Rep. 2016;6:39035 pubmed 出版商
Huang J, Woods P, Normolle D, Goff J, Benos P, Stehle C, et al. Downregulation of estrogen receptor and modulation of growth of breast cancer cell lines mediated by paracrine stromal cell signals. Breast Cancer Res Treat. 2017;161:229-243 pubmed 出版商
Li W, Hua L, Qu P, Yan W, Ming C, Jun Y, et al. NLRP3 inflammasome: a novel link between lipoproteins and atherosclerosis. Arch Med Sci. 2016;12:950-958 pubmed
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed 出版商
Oliver R, Lovric V, Yu Y, Christou C, Aiken S, Cooper J, et al. Development of a Novel Model for the Assessment of Dead-Space Management in Soft Tissue. PLoS ONE. 2015;10:e0136514 pubmed 出版商
Alfaidi M, Wilson H, Daigneault M, Burnett A, Ridger V, Chamberlain J, et al. Neutrophil elastase promotes interleukin-1β secretion from human coronary endothelium. J Biol Chem. 2015;290:24067-78 pubmed 出版商
Ansari M, Dutta S, Veettil M, Dutta D, Iqbal J, Kumar B, et al. Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses. PLoS Pathog. 2015;11:e1005019 pubmed 出版商
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol. 2012;10:e1001395 pubmed 出版商
Nicolaidou V, Wong M, Redpath A, Ersek A, Baban D, Williams L, et al. Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation. PLoS ONE. 2012;7:e39871 pubmed 出版商
Zielinski C, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, et al. Pathogen-induced human TH17 cells produce IFN-? or IL-10 and are regulated by IL-1?. Nature. 2012;484:514-8 pubmed 出版商
Aliahmadi E, Gramlich R, Grützkau A, Hitzler M, Krüger M, Baumgrass R, et al. TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur J Immunol. 2009;39:1221-30 pubmed 出版商
Li J, Yin H, Yuan J. Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity. J Cell Biol. 2008;181:321-33 pubmed 出版商
Acosta Rodriguez E, Napolitani G, Lanzavecchia A, Sallusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol. 2007;8:942-9 pubmed
van Grevenstein W, Hofland L, van Rossen M, van Koetsveld P, Jeekel J, van Eijck C. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers. Dig Dis Sci. 2007;52:2775-83 pubmed
Lee K, Ho S, Lin H, Lin S, Liu C, Huang C, et al. Neutrophil-derived elastase induces TGF-beta1 secretion in human airway smooth muscle via NF-kappaB pathway. Am J Respir Cell Mol Biol. 2006;35:407-14 pubmed
Banks W, Farr S, La Scola M, Morley J. Intravenous human interleukin-1alpha impairs memory processing in mice: dependence on blood-brain barrier transport into posterior division of the septum. J Pharmacol Exp Ther. 2001;299:536-41 pubmed
Yates S, Burgess L, Kocsis Angle J, Antal J, Dority M, Embury P, et al. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia. J Neurochem. 2000;74:1017-25 pubmed
图像
图像 1 :
安迪生物R&D MAB201-100 图像 1
Detection of Human IL-1ss/IL-1F2 antibody by Western Blot.
产品信息
品牌 :
R&D Systems
master code :
MAB201
SKU号 :
MAB201-100
产品名称 :
IL-1乙/IL-1F2抗体
描述 :
The Human IL-1 beta/IL-1F2 Antibody from R&D Systems is a mouse monoclonal antibody to IL-1 beta/IL-1F2. This antibody reacts with human. The Human IL-1 beta/IL-1F2 Antibody has been validated for the following applications: Western Blot, Simple Western, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready.
靶标 :
IL-1乙/IL-1F2
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
8516
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human IL-1 beta/IL-1F2, aa 117-269, Accession # P01584
抗体亚型 :
IgG1
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human IL-1 beta/IL-1F2 in Western blots. Shows less than 5% cross-reactivity with recombinant mouse (rm) IL-1 beta and rpIL-1 beta and no cross-reactivity with rrIL-1 beta , rmIL-1 alpha , rhIL-1ra, rmIL-1ra, or rrIL-1 alpha .
基因符号 :
IL1B
内毒素说明 :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
P01584
应用 :
Western Blot, Simple Western, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready
美元 :
453美元
别名 :
catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.