产品简要
公司名称 :
安迪生物R&D
产品类型 :
抗体
产品名称 :
人类IL-6抗体
目录 :
MAB2061
规格 :
100 ug (also 25 ug, 500 ug)
价格 :
369美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
1936
反应物种 :
人类
应用 :
免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪, 免疫组化-石蜡切片, 抑制或激活实验
更多信息或购买 :
安迪生物R&D 产品网页
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 人类; 5 ug/ml; 图 3d
Eyre R, Alferez D, Santiago Gómez A, Spence K, McConnell J, Hart C, et al. Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling. Nat Commun. 2019;10:5016 pubmed 出版商
  • 抑制或激活实验; 人类; 图 6e
Oon S, Huynh H, Tai T, Ng M, Monaghan K, Biondo M, et al. A cytotoxic anti-IL-3Rα antibody targets key cells and cytokines implicated in systemic lupus erythematosus. JCI Insight. 2016;1:e86131 pubmed 出版商
  • 抑制或激活实验; 人类; 图 6a
Knobloch J, Yanik S, Körber S, Stoelben E, Jungck D, Koch A. TNF?-induced airway smooth muscle cell proliferation depends on endothelin receptor signaling, GM-CSF and IL-6. Biochem Pharmacol. 2016;116:188-99 pubmed 出版商
  • 流式细胞仪; 人类; 图 2g
Piancone F, Saresella M, Marventano I, La Rosa F, Zoppis M, Agostini S, et al. B Lymphocytes in Multiple Sclerosis: Bregs and BTLA/CD272 Expressing-CD19+ Lymphocytes Modulate Disease Severity. Sci Rep. 2016;6:29699 pubmed 出版商
  • 抑制或激活实验; 人类; 图 3d
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 2b
Kobawala T, Trivedi T, Gajjar K, Patel D, Patel G, Ghosh N. Significance of Interleukin-6 in Papillary Thyroid Carcinoma. J Thyroid Res. 2016;2016:6178921 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1
Jhaveri K, Teplinsky E, Silvera D, Valeta Magara A, Arju R, Giashuddin S, et al. Hyperactivated mTOR and JAK2/STAT3 Pathways: Molecular Drivers and Potential Therapeutic Targets of Inflammatory and Invasive Ductal Breast Cancers After Neoadjuvant Chemotherapy. Clin Breast Cancer. 2016;16:113-22.e1 pubmed 出版商
Ashander L, Lie S, Ma Y, Rochet E, Washington J, Furtado J, et al. Neutrophil Activities in Human Ocular Toxoplasmosis: An In Vitro Study With Human Cells. Invest Ophthalmol Vis Sci. 2019;60:4652-4660 pubmed 出版商
Huang H, Zhang Y, Gallegos V, Sorrelle N, Zaid M, Toombs J, et al. Targeting TGFβR2-mutant tumors exposes vulnerabilities to stromal TGFβ blockade in pancreatic cancer. EMBO Mol Med. 2019;11:e10515 pubmed 出版商
Shokri M, Bozorgmehr M, Ghanavatinejad A, Falak R, Aleahmad M, Kazemnejad S, et al. Human menstrual blood-derived stromal/stem cells modulate functional features of natural killer cells. Sci Rep. 2019;9:10007 pubmed 出版商
Blanchette Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, et al. Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer. Oncogene. 2018;37:4013-4032 pubmed 出版商
Hjort M, Hov H, Abdollahi P, Vandsemb E, Fagerli U, Lund B, et al. Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration. Exp Hematol Oncol. 2018;7:8 pubmed 出版商
Tzach Nahman R, Nashef R, Fleissig O, Palmon A, Shapira L, Wilensky A, et al. Oral fibroblasts modulate the macrophage response to bacterial challenge. Sci Rep. 2017;7:11516 pubmed 出版商
Brencicova E, Jagger A, Evans H, Georgouli M, Laios A, Attard Montalto S, et al. Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma. PLoS ONE. 2017;12:e0175712 pubmed 出版商
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed 出版商
Suwara M, Green N, Borthwick L, Mann J, Mayer Barber K, Barron L, et al. IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts. Mucosal Immunol. 2014;7:684-93 pubmed 出版商
Becker T, Boyd S, Mijatov B, Gowrishankar K, Snoyman S, Pupo G, et al. Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor. Oncogene. 2014;33:1158-66 pubmed 出版商
Nakajima N, Van Tin N, Sato Y, Thach H, Katano H, Diep P, et al. Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam. Mod Pathol. 2013;26:357-69 pubmed 出版商
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol. 2012;10:e1001395 pubmed 出版商
Steinbicker A, Sachidanandan C, Vonner A, Yusuf R, Deng D, Lai C, et al. Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood. 2011;117:4915-23 pubmed 出版商
Rodier F, Coppe J, Patil C, Hoeijmakers W, Muñoz D, Raza S, et al. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. Nat Cell Biol. 2009;11:973-9 pubmed 出版商
Maneechotesuwan K, Wamanuttajinda V, Kasetsinsombat K, Huabprasert S, Yaikwawong M, Barnes P, et al. Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. J Allergy Clin Immunol. 2009;123:239-48 pubmed 出版商
Chong D, Boehlke C, Zheng Q, Zhang L, Han Y, Zacks D. Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci. 2008;49:3193-200 pubmed 出版商
Ren Y, Lin C, Li Z, Chen X, Huang X, Lui V, et al. Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis. Histopathology. 2005;46:659-67 pubmed
产品信息
品牌 :
R&D Systems
master code :
MAB2061
SKU号 :
MAB2061-100
产品名称 :
人类IL-6抗体
描述 :
The Human IL-6 Antibody from R&D Systems is a mouse monoclonal antibody to IL-6. This antibody reacts with human. The Human IL-6 Antibody has been validated for the following applications: Immunohistochemistry, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready.
靶标 :
IL-6
类别 :
一抗
单位尺寸 :
100 ug (also 25 ug, 500 ug)
缓冲液 :
Lyophilized from a 0.2 µm filtered solution in PBS and NaCl with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
克隆性 :
单克隆
克隆 :
1936
浓度 :
LYOPH
共轭标签 :
未共轭
宿主 :
小鼠
免疫原 :
E. coli -derived recombinant human IL-6, Val30-Met212, Accession # P05231
抗体亚型 :
IgG2b
纯度 :
Protein A or G purified from hybridoma culture supernatant
物种 :
人类
特异性 :
Detects human IL-6 in direct ELISAs. Does not cross-react with recombinant IL-6 from mouse, rat, or pig.
基因符号 :
白细胞介素-6
功能细节 :
ActivityAssaywCitation not found None None None None
内毒素说明 :
<0.20 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB2061
accessionNumbers :
P05231
应用 :
Immunohistochemistry, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready
2020美元 :
339
2021美元 :
369美元
别名 :
B-cell differentiation factor, B-cell stimulatory factor 2, BSF2, BSF-2, CDF, CTL differentiation factor, HGF, HSF, hybridoma growth factor, IFNB2, IFN-beta-2, IL6, IL-6, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6, MGI-2A
储存 :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
更多信息或购买 :
安迪生物R&D 产品网页
公司信息
安迪生物R&D
上海市长宁区延安西路726号华敏翰尊国际大厦24A1
info@rndsystemschina.com.cn
http://www.rndsystemschina.com.cn
21 52380373
公司总部: 美国
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.